Motif ID: ETS1,2.p2

Z-value: 1.209


Transcription factors associated with ETS1,2.p2:

Gene SymbolEntrez IDGene Name
ETS1 2113 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
ETS2 2114 v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)



Activity profile for motif ETS1,2.p2.

activity profile for motif ETS1,2.p2


Sorted Z-values histogram for motif ETS1,2.p2

Sorted Z-values for motif ETS1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ETS1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_184756101 1.961 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr14_-_106184988 1.406 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr6_+_31661934 1.334 NM_205838
NM_205839
LST1

leukocyte specific transcript 1

chrX_-_40480005 1.302 MED14
mediator complex subunit 14
chr7_-_3049872 1.223 NM_032415
CARD11
caspase recruitment domain family, member 11
chr10_+_129595349 1.114 PTPRE
protein tyrosine phosphatase, receptor type, E
chr12_-_49853155 1.068 NM_001173452
NM_001173453
NM_005653
TFCP2


transcription factor CP2


chr9_-_129707392 1.038 LOC100131355
ST6GALNAC6
hypothetical protein LOC100131355
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr15_+_72861470 1.028 NM_001127190
NM_004383
CSK

c-src tyrosine kinase

chr2_-_242205556 1.023 NM_001164356
THAP4
THAP domain containing 4
chr6_-_11490487 0.990 NM_001142393
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr13_-_100039008 0.982 NM_001195087
A2LD1
AIG2-like domain 1
chr22_+_35586950 0.972 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr10_+_129595289 0.950 NM_006504
PTPRE
protein tyrosine phosphatase, receptor type, E
chrX_-_40479718 0.949 NM_004229
MED14
mediator complex subunit 14
chr5_+_134012133 0.894 NM_021982
SEC24A
SEC24 family, member A (S. cerevisiae)
chr15_+_79376295 0.870 NM_004513
IL16
interleukin 16 (lymphocyte chemoattractant factor)
chrX_-_40479893 0.865 MED14
mediator complex subunit 14
chrX_-_40479607 0.861 MED14
mediator complex subunit 14
chr12_-_47604930 0.859 NM_001143781
FKBP11
FK506 binding protein 11, 19 kDa
chr14_+_74418345 0.852 NM_001933
DLST
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
chr16_+_1696162 0.834 NM_001040439
NM_015133
MAPK8IP3

mitogen-activated protein kinase 8 interacting protein 3

chr19_-_10311262 0.811 NM_002162
ICAM3
intercellular adhesion molecule 3
chr19_+_16860807 0.807 NM_003950
F2RL3
coagulation factor II (thrombin) receptor-like 3
chr17_-_42621626 0.803 CDC27
cell division cycle 27 homolog (S. cerevisiae)
chr4_+_2783764 0.788 SH3BP2
SH3-domain binding protein 2
chr17_-_42621535 0.777 CDC27
cell division cycle 27 homolog (S. cerevisiae)
chr11_-_3104413 0.760 OSBPL5
oxysterol binding protein-like 5
chr1_+_6008956 0.747 NM_003636
NM_172130
KCNAB2

potassium voltage-gated channel, shaker-related subfamily, beta member 2

chr17_-_42621663 0.742 NM_001114091
NM_001256
CDC27

cell division cycle 27 homolog (S. cerevisiae)

chr11_+_10428799 0.734 NM_000480
AMPD3
adenosine monophosphate deaminase 3
chr16_+_29373365 0.729 NM_001014999
NM_001015000
NM_024044
NM_178044
SLX1A-SULT1A3
SLX1A

SLX1B

SLX1A-SULT1A3 read-through transcript
SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)

SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)

chr3_-_123223658 0.722 NM_175924
ILDR1
immunoglobulin-like domain containing receptor 1
chr12_+_111341084 0.720 PTPN11
protein tyrosine phosphatase, non-receptor type 11
chr17_-_31965375 0.720 NM_001033580
NM_001163735
NM_025109
MYO19


myosin XIX


chr18_-_70416018 0.713 LOC400657
hypothetical LOC400657
chr7_-_37454933 0.709 NM_014800
ELMO1
engulfment and cell motility 1
chr1_+_159899528 0.703 NM_001002273
NM_001002274
NM_001002275
NM_001190828
NM_004001
FCGR2B




FCGR2C
Fc fragment of IgG, low affinity IIb, receptor (CD32)




Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
chr11_+_2877486 0.696 NM_183233
SLC22A18
solute carrier family 22, member 18
chr10_+_71060008 0.690 NM_145306
C10orf35
chromosome 10 open reading frame 35
chr15_+_72620570 0.685 NM_006465
ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chr8_-_146023228 0.679 LOC100130027
hypothetical LOC100130027
chr9_-_139043035 0.678 NM_212533
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr1_+_6008999 0.677 KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr19_+_16860871 0.671 F2RL3
coagulation factor II (thrombin) receptor-like 3
chr19_+_47079089 0.669 NM_004706
NM_198977
ARHGEF1

Rho guanine nucleotide exchange factor (GEF) 1

chr21_+_25856311 0.666 MIR155HG
MIR155 host gene (non-protein coding)
chrX_-_7076146 0.652 NM_001135565
NM_001178135
NM_001178136
NM_012080
HDHD1



haloacid dehalogenase-like hydrolase domain containing 1



chr7_+_50318801 0.650 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr16_+_658158 0.649 RHOT2
ras homolog gene family, member T2
chr16_+_658081 0.647 NM_138769
RHOT2
ras homolog gene family, member T2
chr19_+_47079147 0.639 ARHGEF1
Rho guanine nucleotide exchange factor (GEF) 1
chr12_-_109372481 0.635 ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr6_+_1556543 0.630 FOXC1
forkhead box C1
chr19_+_1200882 0.629 MIDN
midnolin
chr5_-_126437070 0.628 NM_001164478
NM_001164479
FLJ44606

glutaredoxin-like protein YDR286C homolog

chr10_-_98470164 0.625 NM_152309
PIK3AP1
phosphoinositide-3-kinase adaptor protein 1
chr12_-_109372462 0.621 ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr12_+_111340918 0.617 NM_002834
PTPN11
protein tyrosine phosphatase, non-receptor type 11
chr2_+_113648020 0.617 NM_012455
PSD4
pleckstrin and Sec7 domain containing 4
chr15_+_72861767 0.617 CSK
c-src tyrosine kinase
chr12_-_6668085 0.611 NM_001039916
ZNF384
zinc finger protein 384
chr2_+_113648036 0.604 PSD4
pleckstrin and Sec7 domain containing 4
chr4_+_2783743 0.601 NM_001145855
SH3BP2
SH3-domain binding protein 2
chr1_-_31003181 0.599 LAPTM5
lysosomal protein transmembrane 5
chr12_+_111341139 0.598 PTPN11
protein tyrosine phosphatase, non-receptor type 11
chr16_-_1419345 0.594 NM_001010878
C16orf91
chromosome 16 open reading frame 91
chr19_+_17495109 0.587 NM_001098524
NM_173544
FAM129C

family with sequence similarity 129, member C

chr2_-_120697148 0.585 TMEM185B
transmembrane protein 185B (pseudogene)
chr22_-_35875890 0.585 NM_000878
IL2RB
interleukin 2 receptor, beta
chr12_-_109372489 0.581 ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chrX_-_134257624 0.579 NM_001185063
NM_007131
ZNF75D

zinc finger protein 75D

chr7_-_44985202 0.576 NM_033054
MYO1G
myosin IG
chr3_-_27738788 0.568 NM_005442
EOMES
eomesodermin
chr3_-_150533948 0.565 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr18_-_70415788 0.563 LOC400657
hypothetical LOC400657
chr7_-_44985175 0.557 MYO1G
myosin IG
chr10_+_49562866 0.556 WDFY4
WDFY family member 4
chr5_+_57823017 0.556 NM_152687
GAPT
GRB2-binding adaptor protein, transmembrane
chr11_-_19038803 0.551 NM_054030
MRGPRX2
MAS-related GPR, member X2
chr1_-_31003260 0.549 NM_006762
LAPTM5
lysosomal protein transmembrane 5
chr7_-_44985084 0.542 MYO1G
myosin IG
chr9_-_21325239 0.540 NM_018847
KLHL9
kelch-like 9 (Drosophila)
chr12_-_10042956 0.538 NM_001099431
NM_016509
CLEC1B

C-type lectin domain family 1, member B

chrX_+_7075820 0.537 STS
steroid sulfatase (microsomal), isozyme S
chr20_-_61809648 0.537 ARFRP1
ADP-ribosylation factor related protein 1
chr16_-_29664765 0.536 NM_175900
C16orf54
chromosome 16 open reading frame 54
chr12_-_3732614 0.533 NM_001144958
NM_001144959
NM_032680
EFCAB4B


EF-hand calcium binding domain 4B


chr11_-_117628211 0.531 NM_198275
MPZL3
myelin protein zero-like 3
chr6_-_26125939 0.530 NM_005325
HIST1H1A
histone cluster 1, H1a
chr3_-_52248182 0.528 NM_007284
TWF2
twinfilin, actin-binding protein, homolog 2 (Drosophila)
chr22_+_36412277 0.528 NM_024313
NOL12
nucleolar protein 12
chr17_-_959007 0.525 NM_001092
ABR
active BCR-related gene
chr8_+_82355322 0.519 NM_001444
FABP5
fatty acid binding protein 5 (psoriasis-associated)
chr18_+_21967813 0.517 NM_001025096
NM_001025097
NM_144662
PSMA8


proteasome (prosome, macropain) subunit, alpha type, 8


chr12_-_3732478 0.512 EFCAB4B
EF-hand calcium binding domain 4B
chr3_-_131948202 0.509 NM_014602
PIK3R4
phosphoinositide-3-kinase, regulatory subunit 4
chr16_+_19329557 0.508 NM_001105248
NM_001105249
TMC5

transmembrane channel-like 5

chr22_+_30072739 0.507 FLJ20464
hypothetical protein FLJ20464
chr4_-_185921384 0.507 ACSL1
acyl-CoA synthetase long-chain family member 1
chr17_-_60208083 0.504 LOC146880
hypothetical LOC146880
chr17_+_9670105 0.501 NM_004246
GLP2R
glucagon-like peptide 2 receptor
chr11_-_118716736 0.496 C1QTNF5
MFRP
C1q and tumor necrosis factor related protein 5
membrane frizzled-related protein
chr12_-_109372543 0.493 ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr6_+_33347776 0.491 NM_022551
RPS18
ribosomal protein S18
chr12_-_109372517 0.490 ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr22_-_30071565 0.489 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr21_+_17807167 0.488 NM_001338
CXADR
coxsackie virus and adenovirus receptor
chr19_+_12778409 0.488 NM_006397
RNASEH2A
ribonuclease H2, subunit A
chr12_-_53071285 0.487 NM_001130967
NM_001130968
ZNF385A

zinc finger protein 385A

chr14_+_20319049 0.487 NM_005615
RNASE6
ribonuclease, RNase A family, k6
chr11_-_103540275 0.487 PDGFD
platelet derived growth factor D
chr19_+_11407467 0.483 PRKCSH
protein kinase C substrate 80K-H
chr16_+_66128843 0.482 NM_001193524
FAM65A
family with sequence similarity 65, member A
chr1_+_24614831 0.479 NM_020448
NIPAL3
NIPA-like domain containing 3
chr1_-_230717850 0.479 NM_020808
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr11_+_18300689 0.478 GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr19_+_11407465 0.473 PRKCSH
protein kinase C substrate 80K-H
chr12_-_108802561 0.471 NM_016433
GLTP
glycolipid transfer protein
chr20_-_47238310 0.470 NM_001037328
NM_004602
NM_017452
NM_017453
NM_017454
STAU1




staufen, RNA binding protein, homolog 1 (Drosophila)




chr11_-_62251503 0.465 HNRNPUL2
heterogeneous nuclear ribonucleoprotein U-like 2
chr17_+_1906262 0.463 NM_001098202
HIC1
hypermethylated in cancer 1
chr20_+_60810610 0.461 NM_002531
NTSR1
neurotensin receptor 1 (high affinity)
chr8_+_146023706 0.458 NM_003416
ZNF7
zinc finger protein 7
chr21_+_42807052 0.456 SLC37A1
solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr1_+_107400789 0.454 NM_018137
PRMT6
protein arginine methyltransferase 6
chr10_+_124020810 0.453 NM_144587
BTBD16
BTB (POZ) domain containing 16
chr1_+_150428404 0.451


chr18_-_59138192 0.450 BCL2
B-cell CLL/lymphoma 2
chr11_-_62251361 0.449 NM_001079559
HNRNPUL2
heterogeneous nuclear ribonucleoprotein U-like 2
chr14_+_23937766 0.448 NM_025081
NYNRIN
NYN domain and retroviral integrase containing
chr2_-_120697441 0.448 TMEM185B
transmembrane protein 185B (pseudogene)
chr10_-_121292139 0.445 NM_001005339
RGS10
regulator of G-protein signaling 10
chr11_+_62285586 0.445 NM_002696
POLR2G
polymerase (RNA) II (DNA directed) polypeptide G
chr11_+_10428443 0.445 NM_001172431
AMPD3
adenosine monophosphate deaminase 3
chr2_+_152899837 0.443 NM_052905
FMNL2
formin-like 2
chr9_-_137992967 0.441 NM_016172
UBAC1
UBA domain containing 1
chr12_-_109372535 0.441 NM_005719
ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr19_+_11407447 0.441 PRKCSH
protein kinase C substrate 80K-H
chr9_+_139292094 0.440 NM_017723
C9orf167
chromosome 9 open reading frame 167
chr11_+_19095215 0.437 NM_001001483
NM_019028
ZDHHC13

zinc finger, DHHC-type containing 13

chr10_-_118670968 0.436 KIAA1598
KIAA1598
chr2_+_37312277 0.434 NM_001083946
NM_144736
C2orf56

chromosome 2 open reading frame 56

chr1_-_159306037 0.434 ARHGAP30
Rho GTPase activating protein 30
chr6_+_33347833 0.429 RPS18
ribosomal protein S18
chr19_-_10091534 0.428 NM_003755
EIF3G
eukaryotic translation initiation factor 3, subunit G
chr20_-_23014828 0.426 NM_012072
CD93
CD93 molecule
chr7_+_101892372 0.424 NM_152892
LRWD1
leucine-rich repeats and WD repeat domain containing 1
chr11_+_66580884 0.424 RHOD
ras homolog gene family, member D
chr1_-_159306210 0.422 ARHGAP30
Rho GTPase activating protein 30
chr16_-_65818401 0.422 NM_001004055
LRRC29
leucine rich repeat containing 29
chr2_+_108604111 0.422 NM_001193484
LIMS1
LIM and senescent cell antigen-like domains 1
chrX_+_16874651 0.422 NM_001080975
NM_004726
REPS2

RALBP1 associated Eps domain containing 2

chr3_-_181879955 0.420 NM_181426
CCDC39
coiled-coil domain containing 39
chrX_-_31000079 0.420 NM_031894
FTHL17
ferritin, heavy polypeptide-like 17
chr19_-_48976852 0.418 KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr11_+_1607580 0.418 NM_001001480
KRTAP5-5
keratin associated protein 5-5
chr1_-_153107084 0.416


chr22_+_29810981 0.415 SMTN
smoothelin
chr8_-_82916982 0.415 NM_022133
NM_152836
NM_152837
SNX16


sorting nexin 16


chr12_-_56422120 0.412 NM_014770
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr9_+_115396020 0.410 NM_144489
RGS3
regulator of G-protein signaling 3
chr1_-_159306273 0.409 ARHGAP30
Rho GTPase activating protein 30
chr8_+_22493928 0.408 NM_176871
NM_198042
PDLIM2

PDZ and LIM domain 2 (mystique)

chr19_-_5631502 0.404 C19orf70
chromosome 19 open reading frame 70
chr10_-_33287184 0.403 NM_002211
ITGB1
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
chr9_-_113977285 0.402 NM_022486
SUSD1
sushi domain containing 1
chr1_-_94147537 0.402 GCLM
glutamate-cysteine ligase, modifier subunit
chr17_-_72151314 0.402 NM_018414
ST6GALNAC1
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
chr22_-_40652724 0.401 NM_052945
TNFRSF13C
tumor necrosis factor receptor superfamily, member 13C
chr14_+_54588066 0.399 NM_144578
MAPK1IP1L
mitogen-activated protein kinase 1 interacting protein 1-like
chr17_-_34159556 0.399 PCGF2
polycomb group ring finger 2
chr14_+_54588138 0.398 MAPK1IP1L
mitogen-activated protein kinase 1 interacting protein 1-like
chr11_-_32772731 0.397 NM_001008391
CCDC73
coiled-coil domain containing 73
chr1_-_158883666 0.397 NM_003037
SLAMF1
signaling lymphocytic activation molecule family member 1
chr1_-_86394695 0.397 NM_152890
COL24A1
collagen, type XXIV, alpha 1
chr22_-_30018329 0.395 NM_001135911
NM_052880
PIK3IP1

phosphoinositide-3-kinase interacting protein 1

chr14_+_104244998 0.394 INF2
inverted formin, FH2 and WH2 domain containing
chrX_+_51562894 0.394 NM_001005332
MAGED1
melanoma antigen family D, 1
chr2_+_37312318 0.393 C2orf56
chromosome 2 open reading frame 56
chr19_+_41177882 0.391 NM_001042631
SDHAF1
succinate dehydrogenase complex assembly factor 1
chr10_+_97879645 0.391 ZNF518A
zinc finger protein 518A
chr7_+_6380614 0.391 NM_006908
NM_018890
RAC1

ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

chr1_+_43539239 0.390 NM_005424
TIE1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr1_-_94147574 0.389 NM_002061
GCLM
glutamate-cysteine ligase, modifier subunit
chr1_-_181826086 0.388 NCF2
neutrophil cytosolic factor 2
chr5_+_65258316 0.387 ERBB2IP
erbb2 interacting protein
chr12_-_56445653 0.386 CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr6_-_33347417 0.385 VPS52
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr2_-_197883703 0.383 ANKRD44
ankyrin repeat domain 44
chr11_+_62285625 0.381 POLR2G
polymerase (RNA) II (DNA directed) polypeptide G
chr22_+_37747063 0.381 NM_152426
APOBEC3D
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D
chr12_-_6103945 0.380 NM_000552
VWF
von Willebrand factor
chr18_+_59767567 0.379 NM_001123366
HMSD
histocompatibility (minor) serpin domain containing
chr15_-_72922482 0.378 ULK3
unc-51-like kinase 3 (C. elegans)
chr15_-_72922533 0.377 ULK3
unc-51-like kinase 3 (C. elegans)
chr15_-_72922577 0.376 NM_001099436
ULK3
unc-51-like kinase 3 (C. elegans)
chr13_-_59635900 0.376 DIAPH3
diaphanous homolog 3 (Drosophila)
chr16_-_65742323 0.376 NM_033309
B3GNT9
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chrX_-_130792297 0.376 LOC286467
hypothetical LOC286467

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.33 2.03e-07 GO:0048583 regulation of response to stimulus
1.68 3.15e-07 GO:0001775 cell activation
1.36 4.60e-06 GO:0009966 regulation of signal transduction
1.34 2.38e-04 GO:0002376 immune system process
2.31 3.40e-04 GO:0050851 antigen receptor-mediated signaling pathway
1.29 4.11e-04 GO:0023051 regulation of signaling
1.16 4.74e-04 GO:0044260 cellular macromolecule metabolic process
1.77 8.05e-04 GO:0045321 leukocyte activation
1.54 8.05e-04 GO:0070271 protein complex biogenesis
1.85 1.58e-03 GO:0046649 lymphocyte activation
2.15 1.66e-03 GO:0002768 immune response-regulating cell surface receptor signaling pathway
1.52 1.73e-03 GO:0006461 protein complex assembly
2.13 4.38e-03 GO:0002429 immune response-activating cell surface receptor signaling pathway
1.57 5.46e-03 GO:0051056 regulation of small GTPase mediated signal transduction
1.33 6.61e-03 GO:0022607 cellular component assembly
1.72 6.96e-03 GO:0030168 platelet activation
1.48 9.17e-03 GO:0009967 positive regulation of signal transduction
2.30 1.20e-02 GO:0042113 B cell activation
1.46 1.20e-02 GO:0023056 positive regulation of signaling
1.19 1.43e-02 GO:0048518 positive regulation of biological process
1.46 1.44e-02 GO:0010647 positive regulation of cell communication
1.39 1.56e-02 GO:0002682 regulation of immune system process
1.43 1.69e-02 GO:0071822 protein complex subunit organization
1.47 1.76e-02 GO:0007596 blood coagulation
1.47 1.76e-02 GO:0050817 coagulation
1.29 1.88e-02 GO:0044085 cellular component biogenesis
1.12 2.24e-02 GO:0043170 macromolecule metabolic process
1.67 2.34e-02 GO:0002694 regulation of leukocyte activation
1.46 2.48e-02 GO:0007599 hemostasis
1.38 2.52e-02 GO:0065003 macromolecular complex assembly
1.65 2.56e-02 GO:0050865 regulation of cell activation
1.38 2.67e-02 GO:0006915 apoptosis
1.37 2.83e-02 GO:0012501 programmed cell death
1.09 3.13e-02 GO:0050794 regulation of cellular process
1.34 3.59e-02 GO:0008219 cell death
1.36 3.61e-02 GO:0006955 immune response
1.19 4.06e-02 GO:0048522 positive regulation of cellular process
1.15 4.38e-02 GO:0016043 cellular component organization
1.68 4.78e-02 GO:0051249 regulation of lymphocyte activation
1.26 4.86e-02 GO:0035556 intracellular signal transduction
1.33 5.00e-02 GO:0016265 death

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.05 3.83e-03 GO:0005622 intracellular
1.06 4.88e-03 GO:0044424 intracellular part
1.10 1.54e-02 GO:0005634 nucleus

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.12 6.45e-07 GO:0005515 protein binding
1.42 1.54e-03 GO:0046983 protein dimerization activity
1.73 3.56e-02 GO:0005085 guanyl-nucleotide exchange factor activity