Motif ID: GLI1..3.p2

Z-value: 1.793


Transcription factors associated with GLI1..3.p2:

Gene SymbolEntrez IDGene Name
GLI1 2735 glioma-associated oncogene homolog 1 (zinc finger protein)
GLI2 2736 GLI-Kruppel family member GLI2
GLI3 2737 GLI-Kruppel family member GLI3



Activity profile for motif GLI1..3.p2.

activity profile for motif GLI1..3.p2


Sorted Z-values histogram for motif GLI1..3.p2

Sorted Z-values for motif GLI1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GLI1..3.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_3732614 1.896 NM_001144958
NM_001144959
NM_032680
 EFCAB4B


EF-hand calcium binding domain 4B


chr22_+_18090118 1.680 SEPT5-GP1BB
SEPT5-GP1BB read-through transcript
chr7_-_110989582 1.654 NM_032549
 IMMP2L
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr1_-_209818675 1.650 NM_021194
 SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr12_-_3732478 1.590 EFCAB4B
EF-hand calcium binding domain 4B
chr1_-_209818576 1.556 SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr9_+_130056513 1.483


chr19_+_13124889 1.370 IER2
immediate early response 2
chr11_-_85053709 1.295 CREBZF
CREB/ATF bZIP transcription factor
chr11_-_64268126 1.281 NM_001098671
 RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr19_+_3490154 1.245 NM_001135580
 C19orf71
chromosome 19 open reading frame 71
chr12_-_113330574 1.220 NM_000192
NM_080717
 TBX5

T-box 5

chr16_+_56259657 1.192 NM_170776
 GPR97
G protein-coupled receptor 97
chr17_+_77582774 1.182 NM_005052
 RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr1_-_75854281 1.181 SLC44A5
solute carrier family 44, member 5
chr19_-_54618410 1.181 NM_178449
 PTH2
parathyroid hormone 2
chr19_+_13124870 1.170 IER2
immediate early response 2
chr1_-_1300680 1.150 NM_017900
 AURKAIP1
aurora kinase A interacting protein 1
chr11_-_32413486 1.097 WT1
Wilms tumor 1
chr16_-_3049336 1.090



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 25 entries
enrichment   p-value GO term description
1.53 1.08e-03 GO:0010628 positive regulation of gene expression
1.50 9.86e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.46 6.92e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.45 4.13e-02 GO:0051254 positive regulation of RNA metabolic process
1.44 1.40e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.31 2.08e-02 GO:0009966 regulation of signal transduction
1.29 4.98e-04 GO:0048523 negative regulation of cellular process
1.28 2.34e-02 GO:0023051 regulation of signaling
1.27 6.22e-04 GO:0048519 negative regulation of biological process
1.25 3.90e-04 GO:0048518 positive regulation of biological process
1.25 3.62e-02 GO:0048583 regulation of response to stimulus
1.24 6.53e-03 GO:0048522 positive regulation of cellular process
1.22 4.19e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.21 2.23e-02 GO:0031326 regulation of cellular biosynthetic process
1.21 2.23e-02 GO:0009889 regulation of biosynthetic process
1.21 3.88e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.20 1.12e-03 GO:0031323 regulation of cellular metabolic process
1.20 4.82e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.19 7.04e-04 GO:0019222 regulation of metabolic process
1.19 3.96e-03 GO:0080090 regulation of primary metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.08 1.17e-02 GO:0005737 cytoplasm
1.07 7.27e-04 GO:0044424 intracellular part
1.06 2.35e-03 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
1.72 1.41e-03 GO:0016563 transcription activator activity
1.44 7.10e-03 GO:0043565 sequence-specific DNA binding
1.35 1.19e-02 GO:0001071 nucleic acid binding transcription factor activity
1.35 1.19e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.17 3.94e-10 GO:0005515 protein binding