Motif ID: HAND1,2.p2

Z-value: 1.610


Transcription factors associated with HAND1,2.p2:

Gene SymbolEntrez IDGene Name
HAND1 9421 heart and neural crest derivatives expressed 1
HAND2 9464 heart and neural crest derivatives expressed 2



Activity profile for motif HAND1,2.p2.

activity profile for motif HAND1,2.p2


Sorted Z-values histogram for motif HAND1,2.p2

Sorted Z-values for motif HAND1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HAND1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_105845570 2.985 IGHA1
immunoglobulin heavy constant alpha 1
chrX_+_49718954 1.963 NM_000084
CLCN5
chloride channel 5
chr16_-_20246309 1.807 NM_001007240
NM_001007241
NM_001007242
NM_001502
GP2



glycoprotein 2 (zymogen granule membrane)



chr14_+_19365447 1.439 NM_001004723
OR4N2
olfactory receptor, family 4, subfamily N, member 2
chr20_-_43370333 1.373 NM_003833
NM_030590
NM_030592
MATN4


matrilin 4


chr6_-_39180390 1.348 C6orf64
chromosome 6 open reading frame 64
chr4_+_76700281 1.324 NM_178497
C4orf26
chromosome 4 open reading frame 26
chr16_-_28515868 1.254 NM_001054
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr16_-_45339605 1.185 NM_182493
MYLK3
myosin light chain kinase 3
chr17_+_16259812 1.171 TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr14_-_87806913 1.156 NM_138318
KCNK10
potassium channel, subfamily K, member 10
chr19_+_59107802 1.111 NM_031896
CACNG7
calcium channel, voltage-dependent, gamma subunit 7
chr2_-_138762909 1.110


chr6_-_25940247 1.093 NM_005074
SLC17A1
solute carrier family 17 (sodium phosphate), member 1
chr12_-_56496107 1.040 NM_006576
AVIL
advillin
chr17_+_16259636 1.033 TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr9_-_135074364 1.025 NM_014581
OBP2B
OBP2A
odorant binding protein 2B
odorant binding protein 2A
chr17_-_39630951 1.004 NM_001098833
NM_020218
ATXN7L3

ataxin 7-like 3

chr1_-_92724181 0.997 NM_001127216
GFI1
growth factor independent 1 transcription repressor
chr20_-_1113116 0.978 NM_018354
C20orf46
chromosome 20 open reading frame 46
chr12_+_111900650 0.964 NM_001032731
NM_002535
NM_016817
OAS2


2'-5'-oligoadenylate synthetase 2, 69/71kDa


chr17_+_16259573 0.941 NM_016113
TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr22_+_23329113 0.940 NM_001032364
NM_005265
GGT1

gamma-glutamyltransferase 1

chr11_-_62753574 0.917 NM_199352
SLC22A25
solute carrier family 22, member 25
chr7_-_1562272 0.917 NM_001097620
TMEM184A
transmembrane protein 184A
chr21_+_41616590 0.910 FAM3B
family with sequence similarity 3, member B
chr16_+_56286212 0.900 NM_032269
CCDC135
coiled-coil domain containing 135
chr2_-_108972048 0.896 EDAR
ectodysplasin A receptor
chr10_+_118946989 0.888 NM_181840
KCNK18
potassium channel, subfamily K, member 18
chr14_-_105589467 0.880 LOC100126583
IGHA1
IGHG1
IGHG2
IGHM
hypothetical LOC100126583
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant mu
chr18_+_59571256 0.870 NM_001040147
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr19_+_3659358 0.857 TJP3
tight junction protein 3 (zona occludens 3)
chr14_-_64479198 0.854 NM_002083
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr14_-_105712630 0.841 IGHV4-31
IGHA1
IGHA2
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
chrX_+_106030049 0.823 NM_001171092
CLDN2
claudin 2
chr7_+_133982070 0.823 NM_001724
NM_199186
BPGM

2,3-bisphosphoglycerate mutase

chr2_-_73781974 0.823 NM_016347
NAT8B
N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene)
chr14_-_105862080 0.822 IGHV4-31
IGHA1
IGHD
IGHG1
IGHG2
IGHG3
IGHM
SCFV
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
single-chain Fv fragment
chr14_+_23527866 0.809 NM_198083
DHRS4
DHRS4L2
dehydrogenase/reductase (SDR family) member 4
dehydrogenase/reductase (SDR family) member 4 like 2
chr13_+_112860968 0.789 NM_003891
PROZ
protein Z, vitamin K-dependent plasma glycoprotein
chr1_+_154573728 0.772 NM_144627
C1orf182
chromosome 1 open reading frame 182
chr1_-_154988647 0.768 NM_001126051
NM_001126050
HDGF

hepatoma-derived growth factor

chr6_-_133161318 0.764 NM_052831
C6orf192
chromosome 6 open reading frame 192
chr12_-_55134692 0.739 NM_012064
MIP
major intrinsic protein of lens fiber
chr2_+_228386800 0.734 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr20_+_29420081 0.712 NM_054112
DEFB118
defensin, beta 118
chr20_+_16676997 0.709 NM_020157
OTOR
otoraplin
chr16_-_20495126 0.703 NM_001105069
NM_182617
ACSM2B

acyl-CoA synthetase medium-chain family member 2B

chr9_-_111253484 0.701 NM_001145369
NM_001145370
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr22_+_23333610 0.699 NM_001032365
GGT1
gamma-glutamyltransferase 1
chr1_+_52642802 0.683 NM_032864
PRPF38A
PRP38 pre-mRNA processing factor 38 (yeast) domain containing A
chr1_+_52642826 0.676 PRPF38A
PRP38 pre-mRNA processing factor 38 (yeast) domain containing A
chr19_+_17906904 0.667 NM_138442
CCDC124
coiled-coil domain containing 124
chr16_+_28413421 0.666 NM_018690
APOBR
apolipoprotein B receptor
chr16_-_31054321 0.653 PRSS8
protease, serine, 8
chr6_-_30760413 0.647 KIAA1949
KIAA1949
chr1_+_205038837 0.647 NM_153758
IL19
interleukin 19
chr1_+_557269 0.625


chr11_+_22646229 0.624 NM_177553
GAS2
growth arrest-specific 2
chrX_-_48213508 0.624 SLC38A5
solute carrier family 38, member 5
chr16_+_21152516 0.617 NM_145865
ANKS4B
ankyrin repeat and sterile alpha motif domain containing 4B
chr17_+_71232370 0.616 NM_001005619
ITGB4
integrin, beta 4
chr17_-_36587965 0.613 NM_033062
KRTAP4-2
keratin associated protein 4-2
chrX_+_130505630 0.611 NM_001004486
OR13H1
olfactory receptor, family 13, subfamily H, member 1
chr10_+_95507555 0.607 NM_005097
LGI1
leucine-rich, glioma inactivated 1
chr6_-_167491305 0.603 NM_005299
GPR31
G protein-coupled receptor 31
chr22_+_43451600 0.601 PRR5
proline rich 5 (renal)
chr2_+_218954995 0.595 NM_000578
SLC11A1
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
chr1_-_166149867 0.587 NM_001167749
NM_018417
ADCY10

adenylate cyclase 10 (soluble)

chr15_+_34720097 0.579 NM_032499
C15orf41
chromosome 15 open reading frame 41
chr2_-_42441798 0.577 NM_004718
COX7A2L
cytochrome c oxidase subunit VIIa polypeptide 2 like
chr16_+_20370359 0.570 NM_001010845
ACSM2A
acyl-CoA synthetase medium-chain family member 2A
chr15_+_67393795 0.569 NM_001104554
PAQR5
progestin and adipoQ receptor family member V
chr9_+_137577805 0.569 NM_014582
OBP2A
odorant binding protein 2A
chr11_+_5558682 0.563 NM_001005162
OR52B6
olfactory receptor, family 52, subfamily B, member 6
chr6_+_167445284 0.561 NM_004367
CCR6
chemokine (C-C motif) receptor 6
chr6_+_6533932 0.555 NM_004271
LY86
lymphocyte antigen 86
chr7_-_100630912 0.554 NM_178176
MOGAT3
monoacylglycerol O-acyltransferase 3
chr11_+_359723 0.544 NM_178537
B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr12_+_56114724 0.543 NM_005538
INHBC
inhibin, beta C
chr14_-_22947320 0.542 NM_002471
MYH6
myosin, heavy chain 6, cardiac muscle, alpha
chr11_-_63087430 0.540 NM_017878
HRASLS2
HRAS-like suppressor 2
chr3_+_51870684 0.539 NM_203424
IQCF2
IQ motif containing F2
chr1_+_556968 0.529


chr8_-_38577891 0.522


chr10_-_73149505 0.522 NM_001164375
C10orf105
chromosome 10 open reading frame 105
chr17_-_35328368 0.516 NM_001042471
NM_001165958
NM_001165959
GSDMB


gasdermin B


chr2_-_127817143 0.515 NM_006609
MAP3K2
mitogen-activated protein kinase kinase kinase 2
chr19_+_41085221 0.514 NM_001007469
NM_014266
HCST

hematopoietic cell signal transducer

chr10_+_18669619 0.507 NM_201590
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr5_+_140200995 0.506 NM_018911
NM_031856
PCDHA8

protocadherin alpha 8

chr5_-_147266257 0.504 NM_206966
C5orf46
chromosome 5 open reading frame 46
chr1_+_154178103 0.496 NM_181885
RXFP4
relaxin/insulin-like family peptide receptor 4
chr6_+_44299482 0.493 SLC29A1
solute carrier family 29 (nucleoside transporters), member 1
chrX_-_48213545 0.489 NM_033518
SLC38A5
solute carrier family 38, member 5
chr22_+_40286957 0.488 NM_014460
CSDC2
cold shock domain containing C2, RNA binding
chr15_-_88023576 0.481 NM_001145311
NM_002666
PLIN1

perilipin 1

chr14_-_23846993 0.477 CIDEB
cell death-inducing DFFA-like effector b
chr1_-_155936904 0.475 NM_052939
FCRL3
Fc receptor-like 3
chr2_-_144768529 0.472 NM_001006636
GTDC1
glycosyltransferase-like domain containing 1
chr16_-_86527608 0.470 NM_001739
CA5A
carbonic anhydrase VA, mitochondrial
chr1_+_159899528 0.470 NM_001002273
NM_001002274
NM_001002275
NM_001190828
NM_004001
FCGR2B




FCGR2C
Fc fragment of IgG, low affinity IIb, receptor (CD32)




Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
chr7_+_111879348 0.463 NM_001197079
IFRD1
interferon-related developmental regulator 1
chr20_+_2309553 0.462 NM_198994
TGM6
transglutaminase 6
chr14_+_22845851 0.461 NM_004050
BCL2L2-PABPN1
BCL2L2
BCL2L2-PABPN1 read-through transcript
BCL2-like 2
chr2_+_74913289 0.450 NM_000189
HK2
hexokinase 2
chr6_-_34632061 0.447 NM_012391
SPDEF
SAM pointed domain containing ets transcription factor
chr4_-_40326603 0.447 NM_001098634
RBM47
RNA binding motif protein 47
chrX_-_32083506 0.443 NM_004013
NM_004020
NM_004021
NM_004022
NM_004023
DMD




dystrophin




chr17_-_36346240 0.442 KRT23
keratin 23 (histone deacetylase inducible)
chr19_+_40465249 0.440 NM_021175
HAMP
hepcidin antimicrobial peptide
chr20_+_71230 0.436 NM_030931
DEFB126
defensin, beta 126
chrX_+_129363575 0.434 NM_016024
RBMX2
RNA binding motif protein, X-linked 2
chr11_-_64459910 0.433 NM_130769
GPHA2
glycoprotein hormone alpha 2
chr20_+_36643251 0.430 NM_001018082
ADIG
adipogenin
chr3_+_40522533 0.427 NM_175888
ZNF620
zinc finger protein 620
chr7_-_150385867 0.422 CDK5
cyclin-dependent kinase 5
chr11_-_60880799 0.419 NM_001161452
CYBASC3
cytochrome b, ascorbate dependent 3
chr8_-_82769761 0.419 NM_001010893
SLC10A5
solute carrier family 10 (sodium/bile acid cotransporter family), member 5
chr14_-_106240998 0.416 IGHV1-69
IGHG1
immunoglobulin heavy variable 1-69
immunoglobulin heavy constant gamma 1 (G1m marker)
chr2_+_113591940 0.415 NM_000577
NM_173841
NM_173843
IL1RN


interleukin 1 receptor antagonist


chr19_-_56196611 0.415 NM_007196
NM_144505
NM_144506
NM_144507
KLK8



kallikrein-related peptidase 8



chr12_-_51629874 0.414 KRT8
keratin 8
chr19_-_7702977 0.407 NM_198492
CLEC4G
C-type lectin domain family 4, member G
chr11_-_64520964 0.406 NM_138456
BATF2
basic leucine zipper transcription factor, ATF-like 2
chr14_-_106241445 0.405 IGHV4-31
IGHV1-69
IGHA1
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 1-69
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr1_-_181540631 0.402 NM_170706
NMNAT2
nicotinamide nucleotide adenylyltransferase 2
chr14_-_20694023 0.401 NM_001004731
OR5AU1
olfactory receptor, family 5, subfamily AU, member 1
chr1_-_110085182 0.400 NM_000849
GSTM3
glutathione S-transferase mu 3 (brain)
chr3_+_99733432 0.397 NM_005290
GPR15
G protein-coupled receptor 15
chr1_-_199348316 0.397 NM_000069
CACNA1S
calcium channel, voltage-dependent, L type, alpha 1S subunit
chr14_-_30927931 0.395 NM_015473
HEATR5A
HEAT repeat containing 5A
chr16_-_29817841 0.391 NM_001114099
NM_001114100
NM_012410
NM_201575
SEZ6L2



seizure related 6 homolog (mouse)-like 2



chr6_+_31016755 0.391 NM_080870
DPCR1
diffuse panbronchiolitis critical region 1
chr14_+_23838900 0.390 NM_174913
C14orf21
chromosome 14 open reading frame 21
chr11_+_55617328 0.389 NM_001003750
OR8I2
olfactory receptor, family 8, subfamily I, member 2
chr19_-_40996040 0.389 NM_021232
PRODH2
proline dehydrogenase (oxidase) 2
chr1_-_158948176 0.384 NM_001778
CD48
CD48 molecule
chr16_-_31054563 0.383 NM_002773
PRSS8
protease, serine, 8
chr19_-_63715135 0.377 NM_012254
SLC27A5
solute carrier family 27 (fatty acid transporter), member 5
chr14_-_23846904 0.377 CIDEB
cell death-inducing DFFA-like effector b
chr20_+_9236446 0.376 NM_000933
PLCB4
phospholipase C, beta 4
chr6_+_29732736 0.376 NM_001008228
NM_001008229
NM_001170418
NM_002433
NM_206809
NM_206810
NM_206811
NM_206812
NM_206814
MOG








myelin oligodendrocyte glycoprotein








chr11_+_118463906 0.375 NM_001024382
HMBS
hydroxymethylbilane synthase
chr14_+_23492780 0.375 NM_021004
DHRS4
dehydrogenase/reductase (SDR family) member 4
chr1_+_199519202 0.374 NM_000299
NM_001005337
PKP1

plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)

chr11_+_18150959 0.372 NM_054032
MRGPRX4
MAS-related GPR, member X4
chr10_+_82287637 0.372 NM_207372
SH2D4B
SH2 domain containing 4B
chr2_+_68815416 0.365 NM_001007231
NM_001166277
ARHGAP25

Rho GTPase activating protein 25

chr20_+_764710 0.364 NM_207121
FAM110A
family with sequence similarity 110, member A
chr6_-_135312899 0.364 NM_001193480
NM_022568
NM_170771
ALDH8A1


aldehyde dehydrogenase 8 family, member A1


chr17_+_35038276 0.363 NM_181505
PPP1R1B
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr11_-_5130174 0.354 NM_012375
OR52A1
olfactory receptor, family 52, subfamily A, member 1
chr17_-_36899641 0.353 NM_003771
KRT36
keratin 36
chr20_+_43764068 0.349 NM_172005
WFDC13
WAP four-disulfide core domain 13
chr16_+_14835087 0.349 NM_014287
NOMO1
NOMO2
NODAL modulator 1
NODAL modulator 2
chr21_+_43024936 0.348 PDE9A
phosphodiesterase 9A
chr10_+_124135574 0.347 NM_001195608
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr19_+_10404110 0.346 NM_001111309
PDE4A
phosphodiesterase 4A, cAMP-specific
chr8_-_145661545 0.346 NM_032687
NM_001129888
CYHR1

cysteine/histidine-rich 1

chr7_-_83108682 0.345 NM_001178129
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr19_-_51236113 0.344 NM_001002923
IGFL4
IGF-like family member 4
chr20_-_29441946 0.340 NM_153289
NM_153323
NM_173460
DEFB119


defensin, beta 119


chr5_-_150928697 0.336 NM_001447
FAT2
FAT tumor suppressor homolog 2 (Drosophila)
chr20_-_1257809 0.334 NM_080489
SDCBP2
syndecan binding protein (syntenin) 2
chr3_+_134976965 0.332 TF
transferrin
chr2_+_113533155 0.332 NM_012275
IL1F5
interleukin 1 family, member 5 (delta)
chr19_-_47623340 0.331 NM_005357
LIPE
lipase, hormone-sensitive
chr5_-_176769094 0.330 F12
coagulation factor XII (Hageman factor)
chr19_-_56163815 0.329 NM_001012964
NM_001012965
KLK6

kallikrein-related peptidase 6

chr2_-_88208650 0.327 NM_001443
FABP1
fatty acid binding protein 1, liver
chr2_-_31293882 0.325 NM_001145122
CAPN14
calpain 14
chr11_+_89624017 0.325


chr2_-_73723001 0.324 NM_003960
NAT8
N-acetyltransferase 8 (GCN5-related, putative)
chr8_-_30121741 0.323 NM_001100916
MBOAT4
membrane bound O-acyltransferase domain containing 4
chr6_-_41781655 0.323 TFEB
transcription factor EB
chr14_+_87560646 0.323 LOC283587
hypothetical protein LOC283587
chr11_-_113082233 0.322 NM_030770
TMPRSS5
transmembrane protease, serine 5
chr20_-_1257782 0.322 SDCBP2
syndecan binding protein (syntenin) 2
chr2_+_218929822 0.321 NM_198559
C2orf62
chromosome 2 open reading frame 62
chr11_+_45899747 0.321 NM_152312
GYLTL1B
glycosyltransferase-like 1B
chr3_+_196933422 0.320 NM_152673
MUC20
mucin 20, cell surface associated
chr20_+_43943254 0.318 NM_080603
ZSWIM1
zinc finger, SWIM-type containing 1
chr11_+_117720268 0.316 NM_000073
CD3G
CD3g molecule, gamma (CD3-TCR complex)
chr14_-_105542441 0.313 IGLJ3
IGHA1
IGHG1
IGHM
immunoglobulin lambda joining 3
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr20_-_62052922 0.311 NM_001193379
UCKL1
uridine-cytidine kinase 1-like 1
chr16_+_6009095 0.309 NM_001142333
NM_018723
RBFOX1

RNA binding protein, fox-1 homolog (C. elegans) 1

chr22_+_43451351 0.308 NM_001017530
NM_001198721
NM_015366
PRR5


proline rich 5 (renal)


chr16_+_76613912 0.307 NM_005752
CLEC3A
C-type lectin domain family 3, member A
chr8_-_19584373 0.306 NM_018371
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr20_+_2744947 0.306 NM_001167670
LOC100288797
hypothetical protein LOC100288797
chr22_-_21814208 0.305 NM_014433
RTDR1
rhabdoid tumor deletion region gene 1
chr18_+_9092618 0.305 NM_021074
NDUFV2
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
chr16_+_2450081 0.304 NM_025108
C16orf59
chromosome 16 open reading frame 59
chrX_-_69396241 0.303 NM_002565
P2RY4
pyrimidinergic receptor P2Y, G-protein coupled, 4
chr11_-_119504726 0.303 TRIM29
tripartite motif containing 29
chr6_-_43384507 0.303 NM_206922
CRIP3
cysteine-rich protein 3
chr6_+_30964441 0.302 NM_013994
DDR1
discoidin domain receptor tyrosine kinase 1
chr1_+_157676135 0.298 NM_012351
OR10J1
olfactory receptor, family 10, subfamily J, member 1
chr1_-_41722883 0.297 NM_001956
EDN2
endothelin 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.14 7.41e-05 GO:0007606 sensory perception of chemical stimulus
2.11 8.66e-04 GO:0007608 sensory perception of smell
1.72 2.44e-03 GO:0007600 sensory perception
2.28 3.59e-02 GO:0008202 steroid metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.50 4.27e-06 GO:0005576 extracellular region
1.32 5.00e-06 GO:0071944 cell periphery
1.32 5.39e-06 GO:0005886 plasma membrane
1.22 2.13e-05 GO:0044425 membrane part
1.18 6.62e-05 GO:0016020 membrane
1.22 3.61e-04 GO:0031224 intrinsic to membrane
1.23 4.37e-04 GO:0016021 integral to membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.60 7.22e-07 GO:0004872 receptor activity
1.43 2.71e-04 GO:0004871 signal transducer activity
1.43 2.71e-04 GO:0060089 molecular transducer activity
2.08 6.38e-04 GO:0004984 olfactory receptor activity
4.85 1.75e-03 GO:0003823 antigen binding
2.67 4.93e-03 GO:0004252 serine-type endopeptidase activity
2.40 2.11e-02 GO:0008236 serine-type peptidase activity
2.36 2.85e-02 GO:0017171 serine hydrolase activity
12.92 3.63e-02 GO:0032052 bile acid binding
1.56 3.95e-02 GO:0004930 G-protein coupled receptor activity
1.44 4.81e-02 GO:0004888 transmembrane receptor activity