Motif ID: HBP1_HMGB_SSRP1_UBTF.p2

Z-value: 2.124


Transcription factors associated with HBP1_HMGB_SSRP1_UBTF.p2:

Gene SymbolEntrez IDGene Name
HBP1 26959 HMG-box transcription factor 1
HMGB2 3148 high-mobility group box 2
HMGB3 3149 high-mobility group box 3
SSRP1 6749 structure specific recognition protein 1
UBTF 7343 upstream binding transcription factor, RNA polymerase I



Activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2.

activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2


Sorted Z-values histogram for motif HBP1_HMGB_SSRP1_UBTF.p2

Sorted Z-values for motif HBP1_HMGB_SSRP1_UBTF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HBP1_HMGB_SSRP1_UBTF.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_81544432 6.595 LPHN2
latrophilin 2
chrX_+_135079461 4.380 NM_001167819
 FHL1
four and a half LIM domains 1
chr9_+_108665168 4.354 NM_021224
 ZNF462
zinc finger protein 462
chr1_+_161305188 4.112 NM_005613
 RGS4
regulator of G-protein signaling 4
chr9_-_23816062 3.578 NM_004432
 ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr1_-_224993498 3.569 NM_002221
 ITPKB
inositol 1,4,5-trisphosphate 3-kinase B
chr4_-_186814852 3.342 SORBS2
sorbin and SH3 domain containing 2
chr2_-_207738858 3.290 NM_003709
 KLF7
Kruppel-like factor 7 (ubiquitous)
chr11_+_131286513 3.007 NTM
neurotrimin
chr8_-_6407882 2.961 NM_001118887
NM_001118888
NM_001147
 ANGPT2


angiopoietin 2


chr7_-_104696678 2.909 NM_182691
 SRPK2
SRSF protein kinase 2
chr7_-_27186400 2.880 NM_153715
 HOXA10
homeobox A10
chrX_+_123062143 2.806 STAG2
stromal antigen 2
chr13_-_73605914 2.734 NM_007249
 KLF12
Kruppel-like factor 12
chr8_-_72436519 2.535 EYA1
eyes absent homolog 1 (Drosophila)
chr6_-_56824672 2.519 DST
dystonin
chr3_+_174598937 2.386 NM_014932
 NLGN1
neuroligin 1
chr2_-_160181206 2.281 NM_013450
 BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr9_+_126460511 2.251


chr7_-_26202626 2.248 HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 123 entries
enrichment   p-value GO term description
3.07 2.67e-06 GO:0048706 embryonic skeletal system development
2.95 2.53e-05 GO:0030336 negative regulation of cell migration
2.95 2.53e-05 GO:2000146 negative regulation of cell motility
2.92 1.22e-05 GO:0051271 negative regulation of cellular component movement
2.69 1.30e-04 GO:0040013 negative regulation of locomotion
2.66 4.80e-02 GO:0048704 embryonic skeletal system morphogenesis
2.40 2.89e-03 GO:0035107 appendage morphogenesis
2.40 2.89e-03 GO:0035108 limb morphogenesis
2.38 2.51e-03 GO:0048736 appendage development
2.38 2.51e-03 GO:0060173 limb development
2.31 4.33e-02 GO:0030326 embryonic limb morphogenesis
2.31 4.33e-02 GO:0035113 embryonic appendage morphogenesis
2.24 1.64e-04 GO:0009952 anterior/posterior pattern formation
2.23 3.43e-03 GO:0048705 skeletal system morphogenesis
2.14 4.46e-02 GO:0006469 negative regulation of protein kinase activity
2.04 3.75e-07 GO:0001501 skeletal system development
2.02 1.43e-04 GO:0003002 regionalization
1.99 3.33e-03 GO:0007517 muscle organ development
1.88 1.70e-03 GO:0030334 regulation of cell migration
1.87 9.15e-06 GO:0009792 embryo development ending in birth or egg hatching

Gene overrepresentation in compartment category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
2.53 5.18e-04 GO:0030027 lamellipodium
2.27 7.87e-04 GO:0044420 extracellular matrix part
2.22 6.92e-03 GO:0005925 focal adhesion
2.17 6.08e-03 GO:0030055 cell-substrate junction
2.12 1.97e-02 GO:0005924 cell-substrate adherens junction
2.02 3.08e-03 GO:0005912 adherens junction
1.87 1.87e-02 GO:0070161 anchoring junction
1.76 4.17e-04 GO:0005578 proteinaceous extracellular matrix
1.66 1.14e-06 GO:0030054 cell junction
1.61 2.37e-03 GO:0045202 synapse
1.61 5.82e-03 GO:0031012 extracellular matrix
1.40 2.15e-02 GO:0044451 nucleoplasm part
1.15 7.95e-03 GO:0071944 cell periphery
1.15 1.23e-02 GO:0005886 plasma membrane
1.14 1.63e-03 GO:0005634 nucleus

Gene overrepresentation in function category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
7.34 4.05e-02 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity
4.59 6.96e-03 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity
4.59 6.96e-03 GO:0019198 transmembrane receptor protein phosphatase activity
1.84 3.64e-05 GO:0003779 actin binding
1.68 7.09e-08 GO:0043565 sequence-specific DNA binding
1.68 6.34e-06 GO:0008092 cytoskeletal protein binding
1.59 2.98e-09 GO:0001071 nucleic acid binding transcription factor activity
1.59 2.98e-09 GO:0003700 sequence-specific DNA binding transcription factor activity
1.50 1.60e-06 GO:0030528 transcription regulator activity
1.22 1.47e-02 GO:0003677 DNA binding
1.15 9.93e-07 GO:0005515 protein binding
1.06 1.98e-02 GO:0005488 binding