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• Activity deltas table
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Motif ID: HOXA9_MEIS1.p2

Z-value: 0.823

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr20_-_60435983	2.238	NM_080833	C20orf151	chromosome 20 open reading frame 151
chr3_-_191650291	1.939	NM_207316	TMEM207	transmembrane protein 207
chr6_-_29451042	1.535	NM_030959	OR12D3	olfactory receptor, family 12, subfamily D, member 3
chr2_+_114916368	1.290	NM_020868	DPP10	dipeptidyl-peptidase 10 (non-functional)
chr18_+_9875722	1.102	NM_001098529 NM_032243	TXNDC2	thioredoxin domain containing 2 (spermatozoa)
chr11_+_27019084	1.081	NM_003986	BBOX1	butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr9_+_6205804	1.001		IL33	interleukin 33
chr4_+_47403107	0.990
chr19_+_61624	0.942	NM_001005240	OR4F4 OR4F17	olfactory receptor, family 4, subfamily F, member 4 olfactory receptor, family 4, subfamily F, member 17
chr12_-_49708279	0.916	NM_001174125	SLC11A2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr2_+_237143118	0.899	NM_020311	CXCR7	chemokine (C-X-C motif) receptor 7
chr1_-_148854503	0.801
chr3_-_150952944	0.787	NM_016094	COMMD2	COMM domain containing 2
chr19_+_10689763	0.769		DNM2	dynamin 2
chrX_-_131181141	0.741		RAP2C	RAP2C, member of RAS oncogene family
chr17_+_18700385	0.736		PRPSAP2	phosphoribosyl pyrophosphate synthetase-associated protein 2
chr6_-_138581319	0.690	NM_021635	PBOV1	prostate and breast cancer overexpressed 1
chr4_+_123311207	0.668	NM_015312	KIAA1109	KIAA1109
chr1_-_93172119	0.640
chr3_-_150952920	0.624		COMMD2	COMM domain containing 2
chr5_+_132460779	0.621		HSPA4	heat shock 70kDa protein 4
chr19_+_10689750	0.621		DNM2	dynamin 2
chr20_-_44575599	0.617	NM_018102 NM_199441	ZNF334	zinc finger protein 334
chr4_-_166253453	0.607	NM_001100389	TMEM192	transmembrane protein 192
chr12_-_101115677	0.587	NM_002674	PMCH	pro-melanin-concentrating hormone
chr19_+_10689813	0.567		DNM2	dynamin 2
chr11_-_104515670	0.564	NM_021571	CARD18	caspase recruitment domain family, member 18
chr1_+_245818284	0.559	NM_001001915	OR2G2	olfactory receptor, family 2, subfamily G, member 2
chr15_+_64481270	0.559		MAP2K1	mitogen-activated protein kinase kinase 1
chr6_+_73133152	0.538	NM_001168411	RIMS1	regulating synaptic membrane exocytosis 1
chr10_-_76488277	0.533	NM_001003892	DUPD1	dual specificity phosphatase and pro isomerase domain containing 1
chr18_+_18989786	0.521	NM_138375	CABLES1	Cdk5 and Abl enzyme substrate 1
chr12_-_51332214	0.512	NM_000423	KRT2	keratin 2
chr15_-_56093477	0.508	NM_170697	ALDH1A2	aldehyde dehydrogenase 1 family, member A2
chr5_-_160044844	0.506		ATP10B	ATPase, class V, type 10B
chr4_-_39199527	0.506		UGDH	UDP-glucose 6-dehydrogenase
chr19_+_10689772	0.503		DNM2	dynamin 2
chr4_-_166253374	0.493		TMEM192	transmembrane protein 192
chr12_-_10453409	0.493	NM_013431	KLRC4-KLRK1 KLRC4	KLRC4-KLRK1 read-through transcript killer cell lectin-like receptor subfamily C, member 4
chr1_+_144152864	0.489		TXNIP	thioredoxin interacting protein
chr2_-_37269193	0.487	NM_001032377	SULT6B1	sulfotransferase family, cytosolic, 6B, member 1
chr11_+_68124400	0.485		PPP6R3	protein phosphatase 6, regulatory subunit 3
chr3_+_14691609	0.482	NM_001184957 NM_001184958 NM_032137	C3orf20	chromosome 3 open reading frame 20
chr19_+_10689725	0.469	NM_001005360 NM_001005361 NM_001005362 NM_001190716 NM_004945	DNM2	dynamin 2
chr18_+_19826734	0.467	NM_153211	TTC39C	tetratricopeptide repeat domain 39C
chr1_-_115039614	0.448	NM_000036 NM_001172626	AMPD1	adenosine monophosphate deaminase 1
chr8_-_17599438	0.445	NM_020749	MTUS1	microtubule associated tumor suppressor 1
chr6_+_125346208	0.417	NM_152553	RNF217	ring finger protein 217
chr20_+_9406460	0.403		PLCB4	phospholipase C, beta 4
chr9_-_99740243	0.398	NM_197978	HEMGN	hemogen
chr1_-_196776697	0.396	NM_133262 NM_133326	ATP6V1G3	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
chr19_-_3723208	0.396	NM_032753	RAX2	retina and anterior neural fold homeobox 2
chr11_+_56224436	0.388	NM_001005213 NM_001013358	OR9G1 OR9G9	olfactory receptor, family 9, subfamily G, member 1 olfactory receptor, family 9, subfamily G, member 9
chr6_+_29382381	0.386	NM_030946	OR14J1	olfactory receptor, family 14, subfamily J, member 1
chr3_-_121445831	0.375	NM_001168271 NM_153002	GPR156	G protein-coupled receptor 156
chr1_-_150463292	0.366	NM_001009931	HRNR	hornerin
chr14_-_94669547	0.353	NM_001195573	DICER1	dicer 1, ribonuclease type III
chr7_-_84589182	0.348	NM_152754	SEMA3D	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr10_+_35524835	0.345	NM_182721 NM_182722 NM_182723 NM_182724 NM_182725	CREM	cAMP responsive element modulator
chr21_-_31175722	0.342	NM_175858	KRTAP11-1	keratin associated protein 11-1
chr2_-_165133239	0.338		GRB14	growth factor receptor-bound protein 14
chrX_-_130792297	0.336		LOC286467	hypothetical LOC286467
chr3_-_173723754	0.336	NM_001190943 NM_001190942 NM_003810	TNFSF10	tumor necrosis factor (ligand) superfamily, member 10
chr10_+_80942362	0.335	NM_001099692	EIF5AL1	eukaryotic translation initiation factor 5A-like 1
chr18_-_29882555	0.330	NM_001198549	NOL4	nucleolar protein 4
chr3_+_123279439	0.317	NM_006889	CD86	CD86 molecule
chr2_+_88605283	0.311	NM_152670	C2orf51	chromosome 2 open reading frame 51
chr15_-_100280784	0.308	NM_001004195	OR4F4 OR4F17	olfactory receptor, family 4, subfamily F, member 4 olfactory receptor, family 4, subfamily F, member 17
chr22_+_36422940	0.305	NM_001039141	TRIOBP	TRIO and F-actin binding protein
chr4_-_70115037	0.303	NM_001073	UGT2B11	UDP glucuronosyltransferase 2 family, polypeptide B11
chr7_+_143646150	0.302	NM_001005287 NM_001001802	OR2A1 OR2A42	olfactory receptor, family 2, subfamily A, member 1 olfactory receptor, family 2, subfamily A, member 42
chr21_-_46849413	0.299	NM_006272	S100B	S100 calcium binding protein B
chr2_+_169631777	0.298	NM_199204	DHRS9	dehydrogenase/reductase (SDR family) member 9
chr5_+_140780720	0.296	NM_018914 NM_032091 NM_032092	PCDHGA11	protocadherin gamma subfamily A, 11
chr12_-_16649211	0.294		LMO3	LIM domain only 3 (rhombotin-like 2)
chrX_-_137777382	0.291	NM_001139502	FGF13	fibroblast growth factor 13
chr3_+_99484421	0.290	NM_001005482	OR5H2	olfactory receptor, family 5, subfamily H, member 2
chr18_+_54681040	0.287	NM_018181	ZNF532	zinc finger protein 532
chr3_+_58459131	0.283	NM_153331	KCTD6	potassium channel tetramerisation domain containing 6
chr7_+_154351087	0.282		LOC100132707	hypothetical LOC100132707
chr12_+_8866416	0.276	NM_144670	A2ML1	alpha-2-macroglobulin-like 1
chr4_-_122357104	0.276	NM_001128843	TNIP3	TNFAIP3 interacting protein 3
chr17_+_38247493	0.275		PSME3	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chrX_-_71709335	0.272		HDAC8	histone deacetylase 8
chr1_+_24522116	0.266	NM_021180	GRHL3	grainyhead-like 3 (Drosophila)
chrX_-_77469635	0.263	NM_006639	CYSLTR1	cysteinyl leukotriene receptor 1
chr2_+_219432789	0.261	NM_006522	WNT6	wingless-type MMTV integration site family, member 6
chr17_+_53587492	0.259	NM_012374	OR4D1	olfactory receptor, family 4, subfamily D, member 1
chr7_+_90177082	0.258		CDK14	cyclin-dependent kinase 14
chr1_+_151117421	0.253	NM_030663	SMCP	sperm mitochondria-associated cysteine-rich protein
chr11_+_5862076	0.252	NM_001005165	OR52E4	olfactory receptor, family 52, subfamily E, member 4
chr2_+_68445821	0.246	NM_002664	PLEK	pleckstrin
chr1_+_227506751	0.234	NM_006542	SPHAR	S-phase response (cyclin related)
chr21_+_30910614	0.233	NM_181615	KRTAP20-1	keratin associated protein 20-1
chr12_+_7348194	0.230	NM_001080454	ACSM4	acyl-CoA synthetase medium-chain family member 4
chr21_-_35174742	0.230		RUNX1	runt-related transcription factor 1
chr6_+_18495559	0.230	NM_182757	RNF144B	ring finger protein 144B
chr11_-_3104413	0.229		OSBPL5	oxysterol binding protein-like 5
chr17_-_60439764	0.223		GNA13	guanine nucleotide binding protein (G protein), alpha 13
chr17_+_63338500	0.222		BPTF	bromodomain PHD finger transcription factor
chr1_-_84099261	0.220
chr15_+_46285789	0.218	NM_000338 NM_001184832	SLC12A1	solute carrier family 12 (sodium/potassium/chloride transporters), member 1
chr1_-_167865973	0.217	NM_003005	SELP	selectin P (granule membrane protein 140kDa, antigen CD62)
chr5_-_134290789	0.217
chr11_-_7804094	0.214	NM_153445	OR5P3	olfactory receptor, family 5, subfamily P, member 3
chr4_-_40211324	0.213		RBM47	RNA binding motif protein 47
chr6_+_12622286	0.208
chr2_-_43756964	0.207	NM_001101330	LOC728819	hCG1645220
chr11_-_4933518	0.203	NM_001004748	OR51A2	olfactory receptor, family 51, subfamily A, member 2
chr16_-_70306198	0.200	NM_015020	PHLPP2	PH domain and leucine rich repeat protein phosphatase 2
chrX_-_83644054	0.200	NM_001177478 NM_001177479 NM_144657	HDX	highly divergent homeobox
chr19_-_57181862	0.199	NM_021632	ZNF350	zinc finger protein 350
chr12_-_66839589	0.198	NM_000619	IFNG	interferon, gamma
chr8_-_13018123	0.195	NM_001164271	DLC1	deleted in liver cancer 1
chrX_-_43717864	0.191	NM_000266	NDP	Norrie disease (pseudoglioma)
chr22_+_23921072	0.190		KIAA1671	KIAA1671
chr2_+_61243132	0.188	NM_001143959	C2orf74	chromosome 2 open reading frame 74
chr17_+_16061190	0.187	NM_004278	PIGL	phosphatidylinositol glycan anchor biosynthesis, class L
chr3_-_126215069	0.186		HEG1	HEG homolog 1 (zebrafish)
chr11_-_16387001	0.186	NM_001145811	SOX6	SRY (sex determining region Y)-box 6
chr3_+_69895310	0.185	NM_001184967	MITF	microphthalmia-associated transcription factor
chr4_-_120445047	0.184	NM_001170330	C4orf3	chromosome 4 open reading frame 3
chr16_-_71639670	0.184	NM_006885	ZFHX3	zinc finger homeobox 3
chr3_+_99699137	0.182	NM_001004737	OR5K2	olfactory receptor, family 5, subfamily K, member 2
chr1_+_13903936	0.182	NM_012231 NM_015866	PRDM2	PR domain containing 2, with ZNF domain
chr8_+_133856738	0.181	NM_016018 NM_032205 NM_198513	PHF20L1	PHD finger protein 20-like 1
chr11_-_4675524	0.174	NM_030774	OR51E2	olfactory receptor, family 51, subfamily E, member 2
chr4_-_56948345	0.173	NM_181806	AASDH	aminoadipate-semialdehyde dehydrogenase
chr9_+_124321239	0.173	NM_001004452	OR1J4	olfactory receptor, family 1, subfamily J, member 4
chr5_-_9683462	0.173	NM_019599	TAS2R1	taste receptor, type 2, member 1
chr2_+_31310485	0.172		EHD3	EH-domain containing 3
chr3_-_194579207	0.170	NM_198505	ATP13A5	ATPase type 13A5
chr8_+_76614757	0.167	NM_004133	HNF4G	hepatocyte nuclear factor 4, gamma
chr12_+_92595281	0.164	NM_003805	CRADD	CASP2 and RIPK1 domain containing adaptor with death domain
chr8_+_17874128	0.163		PCM1	pericentriolar material 1
chr12_+_53809731	0.158	NM_001005243	OR9K2	olfactory receptor, family 9, subfamily K, member 2
chr5_+_140733664	0.156	NM_018919 NM_032086	PCDHGA6	protocadherin gamma subfamily A, 6
chr12_+_84792203	0.156	NM_006183	NTS	neurotensin
chr9_-_21197141	0.153	NM_002171	IFNA10	interferon, alpha 10
chr11_+_5714253	0.151	NM_001005180	OR56B1	olfactory receptor, family 56, subfamily B, member 1
chr3_+_153014550	0.151	NM_001086	AADAC	arylacetamide deacetylase (esterase)
chr6_+_31698447	0.150
chr8_+_32905027	0.150
chr5_+_140730014	0.146	NM_018924 NM_032097	PCDHGB3	protocadherin gamma subfamily B, 3
chr3_-_52694554	0.143	NM_018313	PBRM1	polybromo 1
chr1_+_67404756	0.142	NM_144701	IL23R	interleukin 23 receptor
chr4_+_70180805	0.142	NM_053039	UGT2B28	UDP glucuronosyltransferase 2 family, polypeptide B28
chr14_+_77939845	0.141	NM_004796	NRXN3	neurexin 3
chr3_-_137395966	0.141	NM_001145417	MSL2	male-specific lethal 2 homolog (Drosophila)
chr10_+_89409332	0.139	NM_001015880 NM_004670	PAPSS2	3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr19_-_51856129	0.135	NM_145056	DACT3	dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)
chr11_+_6854431	0.135	NM_207186	OR10A4	olfactory receptor, family 10, subfamily A, member 4
chrX_+_37750778	0.133	NM_001163335 NM_138780	SYTL5	synaptotagmin-like 5
chr6_+_25760352	0.133	NM_006998	SCGN	secretagogin, EF-hand calcium binding protein
chr5_-_22889192	0.133		CDH12	cadherin 12, type 2 (N-cadherin 2)
chr9_+_102987137	0.132	NM_017753	LPPR1	lipid phosphate phosphatase-related protein type 1
chr14_-_19553191	0.130	NM_001004712	OR4K14	olfactory receptor, family 4, subfamily K, member 14
chr5_+_147695314	0.129	NM_001040433	SPINK9	serine peptidase inhibitor, Kazal type 9
chr18_-_49944986	0.129		MBD2	methyl-CpG binding domain protein 2
chr21_-_44836811	0.128	NM_198688	KRTAP10-6	keratin associated protein 10-6
chr15_+_42815851	0.128	NM_080745 NM_182985	TRIM69	tripartite motif containing 69
chr15_-_23204887	0.126	NM_000462	UBE3A	ubiquitin protein ligase E3A
chr11_-_47502115	0.125	NM_001172639	CELF1	CUGBP, Elav-like family member 1
chr4_+_71298187	0.125	NM_021225	PROL1	proline rich, lacrimal 1
chr2_+_68445936	0.125		PLEK	pleckstrin
chr15_+_36776090	0.124	NM_207444	C15orf53	chromosome 15 open reading frame 53
chrX_+_100361588	0.123	NM_001171184 NM_001939	DRP2	dystrophin related protein 2
chr2_-_160764819	0.118	NM_000888	ITGB6	integrin, beta 6
chr20_+_19818209	0.117	NM_018993	RIN2	Ras and Rab interactor 2
chr11_-_111287657	0.116	NM_001885	CRYAB	crystallin, alpha B
chr16_-_52877868	0.116	NM_024336	IRX3	iroquois homeobox 3
chr19_-_14813688	0.115	NM_001005190	OR7A10	olfactory receptor, family 7, subfamily A, member 10
chr17_+_36647795	0.114	NM_031963	KRTAP9-8	keratin associated protein 9-8
chr5_+_140494971	0.113	NM_015669	PCDHB5	protocadherin beta 5
chr13_-_97916768	0.113		STK24	serine/threonine kinase 24
chr10_-_23673777	0.112	NM_153714	C10orf67	chromosome 10 open reading frame 67
chr6_+_70633168	0.112	NM_001858	COL19A1	collagen, type XIX, alpha 1
chr5_+_127012611	0.111	NM_001048252	CTXN3	cortexin 3
chr6_+_54281161	0.109	NM_014464	TINAG	tubulointerstitial nephritis antigen
chr22_-_39587944	0.109	NM_145174	DNAJB7	DnaJ (Hsp40) homolog, subfamily B, member 7
chr9_+_92629525	0.107	NM_001174167	SYK	spleen tyrosine kinase
chr2_+_28678274	0.105		PLB1	phospholipase B1
chr1_-_157313179	0.105	NM_004833	AIM2	absent in melanoma 2
chr2_-_135498716	0.101	NM_001018046 NM_025052	YSK4	YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)
chr21_+_30724442	0.101	NM_181600	KRTAP13-4	keratin associated protein 13-4
chr18_+_70317548	0.099		CNDP2	CNDP dipeptidase 2 (metallopeptidase M20 family)
chr1_+_144374513	0.098		RNF115	ring finger protein 115
chr12_-_119826433	0.096	NM_139015	SPPL3	signal peptide peptidase 3
chr1_-_144426918	0.095	NM_007053	CD160	CD160 molecule
chr10_+_70517823	0.095	NM_002727	SRGN	serglycin
chr5_+_128328685	0.095		SLC27A6	solute carrier family 27 (fatty acid transporter), member 6
chr15_-_41346346	0.094	NM_004245 NM_201631	TGM5	transglutaminase 5
chr12_+_76749199	0.094	NM_014903	NAV3	neuron navigator 3
chr6_-_29163027	0.093	NM_001005226	OR2B3	olfactory receptor, family 2, subfamily B, member 3
chr1_+_42896634	0.091	NM_006347	PPIH	peptidylprolyl isomerase H (cyclophilin H)
chr1_-_150564302	0.090	NM_002016	FLG	filaggrin
chr12_+_63084317	0.090	NM_007235	XPOT	exportin, tRNA (nuclear export receptor for tRNAs)
chr1_+_169747788	0.090		PRRC2C	proline-rich coiled-coil 2C
chr5_+_179065282	0.089		CANX	calnexin
chr7_+_143287952	0.086	NM_012369	OR2F1	olfactory receptor, family 2, subfamily F, member 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
4.49	6.21e-09	GO:0007608	sensory perception of smell
4.15	2.04e-08	GO:0007606	sensory perception of chemical stimulus
3.09	2.06e-07	GO:0007600	sensory perception
2.31	3.57e-07	GO:0003008	system process
2.50	3.87e-07	GO:0050877	neurological system process
1.51	9.88e-05	GO:0032501	multicellular organismal process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.43	1.03e-02	GO:0005886	plasma membrane
1.41	1.81e-02	GO:0071944	cell periphery

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
4.71	4.09e-10	GO:0004984	olfactory receptor activity
2.83	1.53e-06	GO:0004930	G-protein coupled receptor activity
2.16	2.18e-04	GO:0004888	transmembrane receptor activity
1.96	3.06e-04	GO:0004872	receptor activity
1.78	1.39e-03	GO:0004871	signal transducer activity
1.78	1.39e-03	GO:0060089	molecular transducer activity