Motif ID: MAFB.p2

Z-value: 2.906


Transcription factors associated with MAFB.p2:

Gene SymbolEntrez IDGene Name
MAFB 9935 v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)



Activity profile for motif MAFB.p2.

activity profile for motif MAFB.p2


Sorted Z-values histogram for motif MAFB.p2

Sorted Z-values for motif MAFB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAFB.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_-_22382497 5.245 NM_001142730
 KCTD1
potassium channel tetramerisation domain containing 1
chr13_-_76358370 3.638 KCTD12
potassium channel tetramerisation domain containing 12
chr2_-_192767494 3.387 TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr3_+_195889845 3.156 FAM43A
family with sequence similarity 43, member A
chrX_-_83329562 2.584 NM_014496
 RPS6KA6
ribosomal protein S6 kinase, 90kDa, polypeptide 6
chr3_-_185025989 2.468 NM_024871
 MAP6D1
MAP6 domain containing 1
chr3_-_64186151 2.368 NM_198859
 PRICKLE2
prickle homolog 2 (Drosophila)
chr3_+_106568243 2.203 ALCAM
activated leukocyte cell adhesion molecule
chr6_-_78229838 2.084 NM_000863
 HTR1B
5-hydroxytryptamine (serotonin) receptor 1B
chr13_-_25523164 2.073 NM_001007538
 SHISA2
shisa homolog 2 (Xenopus laevis)
chr18_-_24010944 2.041 CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr20_-_22978141 1.982 NM_000361
 THBD
thrombomodulin
chr21_-_43671355 1.971 NM_173354
 SIK1
salt-inducible kinase 1
chr14_-_60817709 1.968 TMEM30B
transmembrane protein 30B
chr8_+_32525269 1.964 NM_001160002
NM_001160004
NM_001160005
NM_001160007
NM_001160008
NM_004495
NM_013956
NM_013957
NM_013958
NM_013960
NM_013964
 NRG1










neuregulin 1










chr8_-_11096257 1.927 NM_173683
 XKR6
XK, Kell blood group complex subunit-related family, member 6
chr11_+_65594361 1.906 NM_018026
 PACS1
phosphofurin acidic cluster sorting protein 1
chrX_+_153767803 1.890 NM_001007523
NM_001007524
NM_012151
 F8A2
F8A3
F8A1
coagulation factor VIII-associated (intronic transcript) 2
coagulation factor VIII-associated (intronic transcript) 3
coagulation factor VIII-associated (intronic transcript) 1
chr6_+_71434192 1.880 NM_001044305
NM_021940
 SMAP1

small ArfGAP 1

chr10_+_120957084 1.814 NM_005308
 GRK5
G protein-coupled receptor kinase 5

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 139 entries
enrichment   p-value GO term description
1.85 2.04e-03 GO:0060537 muscle tissue development
1.81 1.93e-02 GO:0014706 striated muscle tissue development
1.74 1.47e-04 GO:0048514 blood vessel morphogenesis
1.72 1.38e-03 GO:0007517 muscle organ development
1.69 1.27e-05 GO:0001944 vasculature development
1.68 1.27e-06 GO:0007411 axon guidance
1.66 1.44e-04 GO:0001568 blood vessel development
1.65 1.50e-04 GO:0061061 muscle structure development
1.65 1.53e-02 GO:0043408 regulation of MAPKKK cascade
1.64 1.26e-02 GO:0045664 regulation of neuron differentiation
1.61 1.04e-06 GO:0007409 axonogenesis
1.60 4.09e-08 GO:0000904 cell morphogenesis involved in differentiation
1.60 2.21e-07 GO:0072358 cardiovascular system development
1.60 2.21e-07 GO:0072359 circulatory system development
1.60 2.28e-04 GO:0060284 regulation of cell development
1.60 2.81e-04 GO:0022603 regulation of anatomical structure morphogenesis
1.59 1.19e-06 GO:0048667 cell morphogenesis involved in neuron differentiation
1.58 2.51e-06 GO:0048812 neuron projection morphogenesis
1.56 6.11e-08 GO:0048666 neuron development
1.56 1.92e-02 GO:0000165 MAPKKK cascade

Gene overrepresentation in compartment category:

Showing 1 to 20 of 26 entries
enrichment   p-value GO term description
2.24 3.03e-02 GO:0044306 neuron projection terminus
1.97 8.52e-03 GO:0033267 axon part
1.94 4.68e-02 GO:0030427 site of polarized growth
1.66 1.16e-02 GO:0005912 adherens junction
1.62 8.08e-03 GO:0030424 axon
1.60 2.17e-02 GO:0070161 anchoring junction
1.59 4.53e-07 GO:0045202 synapse
1.57 2.46e-02 GO:0031252 cell leading edge
1.54 4.59e-02 GO:0030425 dendrite
1.49 5.27e-03 GO:0044456 synapse part
1.48 2.69e-04 GO:0043005 neuron projection
1.37 7.00e-04 GO:0030054 cell junction
1.28 5.80e-03 GO:0005626 insoluble fraction
1.27 1.96e-02 GO:0005624 membrane fraction
1.19 2.86e-02 GO:0005856 cytoskeleton
1.17 3.66e-03 GO:0044459 plasma membrane part
1.17 1.06e-02 GO:0005829 cytosol
1.13 4.47e-02 GO:0043234 protein complex
1.10 1.26e-08 GO:0005737 cytoplasm
1.09 2.39e-02 GO:0005634 nucleus

Gene overrepresentation in function category:

Showing 1 to 20 of 22 entries
enrichment   p-value GO term description
1.95 1.12e-02 GO:0019199 transmembrane receptor protein kinase activity
1.74 7.77e-05 GO:0010843 promoter binding
1.73 5.20e-05 GO:0000975 regulatory region DNA binding
1.73 5.20e-05 GO:0001067 regulatory region nucleic acid binding
1.73 5.20e-05 GO:0044212 transcription regulatory region DNA binding
1.69 1.98e-02 GO:0005516 calmodulin binding
1.64 2.19e-02 GO:0005085 guanyl-nucleotide exchange factor activity
1.50 6.46e-09 GO:0043565 sequence-specific DNA binding
1.48 8.23e-03 GO:0016564 transcription repressor activity
1.48 1.34e-02 GO:0008134 transcription factor binding
1.46 1.34e-02 GO:0016563 transcription activator activity
1.38 2.17e-07 GO:0030528 transcription regulator activity
1.36 4.28e-02 GO:0030695 GTPase regulator activity
1.34 5.82e-04 GO:0019899 enzyme binding
1.34 2.63e-02 GO:0008092 cytoskeletal protein binding
1.31 1.60e-04 GO:0001071 nucleic acid binding transcription factor activity
1.31 1.60e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.31 4.29e-02 GO:0004672 protein kinase activity
1.17 4.50e-02 GO:0017076 purine nucleotide binding
1.15 5.83e-15 GO:0005515 protein binding