Motif ID: MAFB.p2

Z-value: 2.906


Transcription factors associated with MAFB.p2:

Gene SymbolEntrez IDGene Name
MAFB 9935 v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)



Activity profile for motif MAFB.p2.

activity profile for motif MAFB.p2


Sorted Z-values histogram for motif MAFB.p2

Sorted Z-values for motif MAFB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAFB.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_-_22382497 5.245 NM_001142730
KCTD1
potassium channel tetramerisation domain containing 1
chr13_-_76358370 3.638 KCTD12
potassium channel tetramerisation domain containing 12
chr2_-_192767494 3.387 TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr3_+_195889845 3.156 FAM43A
family with sequence similarity 43, member A
chrX_-_83329562 2.584 NM_014496
RPS6KA6
ribosomal protein S6 kinase, 90kDa, polypeptide 6
chr3_-_185025989 2.468 NM_024871
MAP6D1
MAP6 domain containing 1
chr3_-_64186151 2.368 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr3_+_106568243 2.203 ALCAM
activated leukocyte cell adhesion molecule
chr6_-_78229838 2.084 NM_000863
HTR1B
5-hydroxytryptamine (serotonin) receptor 1B
chr13_-_25523164 2.073 NM_001007538
SHISA2
shisa homolog 2 (Xenopus laevis)
chr18_-_24010944 2.041 CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr20_-_22978141 1.982 NM_000361
THBD
thrombomodulin
chr21_-_43671355 1.971 NM_173354
SIK1
salt-inducible kinase 1
chr14_-_60817709 1.968 TMEM30B
transmembrane protein 30B
chr8_+_32525269 1.964 NM_001160002
NM_001160004
NM_001160005
NM_001160007
NM_001160008
NM_004495
NM_013956
NM_013957
NM_013958
NM_013960
NM_013964
NRG1










neuregulin 1










chr8_-_11096257 1.927 NM_173683
XKR6
XK, Kell blood group complex subunit-related family, member 6
chr11_+_65594361 1.906 NM_018026
PACS1
phosphofurin acidic cluster sorting protein 1
chrX_+_153767803 1.890 NM_001007523
NM_001007524
NM_012151
F8A2
F8A3
F8A1
coagulation factor VIII-associated (intronic transcript) 2
coagulation factor VIII-associated (intronic transcript) 3
coagulation factor VIII-associated (intronic transcript) 1
chr6_+_71434192 1.880 NM_001044305
NM_021940
SMAP1

small ArfGAP 1

chr10_+_120957084 1.814 NM_005308
GRK5
G protein-coupled receptor kinase 5
chr17_-_28644118 1.779 NM_183377
ACCN1
amiloride-sensitive cation channel 1, neuronal
chr7_-_127458231 1.751 NM_022143
LRRC4
leucine rich repeat containing 4
chr15_+_97009194 1.737 IGF1R
insulin-like growth factor 1 receptor
chr18_-_21185968 1.727 ZNF521
zinc finger protein 521
chr8_+_99508425 1.718 NM_020697
KCNS2
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2
chr5_-_138758783 1.715 NM_001161546
LOC389333
hypothetical protein LOC389333
chrX_-_154341451 1.692 NM_001007523
NM_001007524
NM_012151
F8A2
F8A3
F8A1
coagulation factor VIII-associated (intronic transcript) 2
coagulation factor VIII-associated (intronic transcript) 3
coagulation factor VIII-associated (intronic transcript) 1
chr2_-_31215074 1.688 NM_024572
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr8_+_1936549 1.661 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr11_-_47531179 1.557 CELF1
CUGBP, Elav-like family member 1
chr2_+_207016525 1.540 NM_003812
ADAM23
ADAM metallopeptidase domain 23
chr2_+_176665694 1.530 NM_000523
HOXD13
homeobox D13
chr5_+_140780797 1.524 PCDHGA11
protocadherin gamma subfamily A, 11
chr7_+_33911636 1.511 NM_133468
BMPER
BMP binding endothelial regulator
chr10_-_35970363 1.502 NM_031866
FZD8
frizzled homolog 8 (Drosophila)
chr15_-_37999519 1.495


chr18_-_21186107 1.495 NM_015461
ZNF521
zinc finger protein 521
chr12_-_26166485 1.483 BHLHE41
basic helix-loop-helix family, member e41
chr1_-_1324511 1.457 NM_001039577
NM_030937
CCNL2

cyclin L2

chr12_-_93568336 1.443 NM_020698
TMCC3
transmembrane and coiled-coil domain family 3
chr5_+_129268352 1.441 NM_175856
CHSY3
chondroitin sulfate synthase 3
chr4_-_141293572 1.439 MAML3
mastermind-like 3 (Drosophila)
chrX_-_74062005 1.435 NM_001008537
KIAA2022
KIAA2022
chr8_+_60194328 1.425


chr4_+_166519392 1.417 NM_001873
CPE
carboxypeptidase E
chr16_+_81218142 1.411 CDH13
cadherin 13, H-cadherin (heart)
chr5_-_139402909 1.408 NRG2
neuregulin 2
chr6_+_72653126 1.402 RIMS1
regulating synaptic membrane exocytosis 1
chr15_-_37999717 1.400 GPR176
G protein-coupled receptor 176
chr2_-_31214868 1.400


chr5_+_17270474 1.395 NM_006317
BASP1
brain abundant, membrane attached signal protein 1
chr7_-_27206249 1.388 NM_000522
HOXA13
homeobox A13
chr16_+_81218074 1.380 NM_001257
CDH13
cadherin 13, H-cadherin (heart)
chr4_-_140696740 1.365 NM_030648
SETD7
SET domain containing (lysine methyltransferase) 7
chr6_+_72653369 1.360 NM_014989
RIMS1
regulating synaptic membrane exocytosis 1
chr2_+_112749655 1.354 ZC3H6
zinc finger CCCH-type containing 6
chr19_-_13478037 1.351 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr9_-_92444886 1.350 NM_017594
DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr2_-_73350103 1.336 NM_001080410
FBXO41
F-box protein 41
chr8_+_74369647 1.336 NM_172037
RDH10
retinol dehydrogenase 10 (all-trans)
chr15_+_45796802 1.335 SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr3_+_49002285 1.329 NM_177938
NM_177939
P4HTM

prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)

chr17_-_41626032 1.313 NM_015443
KIAA1267
KIAA1267
chr2_+_112749617 1.312 NM_198581
ZC3H6
zinc finger CCCH-type containing 6
chr2_+_23461802 1.289 NM_052920
KLHL29
kelch-like 29 (Drosophila)
chr5_+_140780720 1.285 NM_018914
NM_032091
NM_032092
PCDHGA11


protocadherin gamma subfamily A, 11


chr3_-_124650081 1.284 NM_183357
ADCY5
adenylate cyclase 5
chr1_+_64012154 1.282 NM_001083592
NM_005012
ROR1

receptor tyrosine kinase-like orphan receptor 1

chr7_-_27149750 1.271 NM_019102
HOXA5
homeobox A5
chr4_-_83569476 1.249 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr5_-_37875538 1.243 NM_000514
GDNF
glial cell derived neurotrophic factor
chr6_+_1556543 1.237 FOXC1
forkhead box C1
chr17_-_39652449 1.231 NM_001076684
UBTF
upstream binding transcription factor, RNA polymerase I
chr5_-_59225377 1.228 NM_001104631
PDE4D
phosphodiesterase 4D, cAMP-specific
chr2_-_227371698 1.228 NM_005544
IRS1
insulin receptor substrate 1
chr5_+_113726203 1.214 KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr10_-_102978678 1.209 NM_006562
LBX1
ladybird homeobox 1
chr11_-_47531342 1.209 NM_006560
CELF1
CUGBP, Elav-like family member 1
chr17_+_27795607 1.194 NM_002815
PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr17_+_27795598 1.193 PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr8_+_31616809 1.170 NM_013962
NRG1
neuregulin 1
chr6_+_43247168 1.167 SRF
serum response factor (c-fos serum response element-binding transcription factor)
chr3_+_141136896 1.166 CLSTN2
calsyntenin 2
chr17_+_27795632 1.164 PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr1_+_6191506 1.160 RNF207
ring finger protein 207
chr18_-_22383066 1.145 NM_001136205
KCTD1
potassium channel tetramerisation domain containing 1
chr17_+_27795645 1.144 PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr1_-_38285033 1.143 NM_002699
POU3F1
POU class 3 homeobox 1
chr3_+_49002774 1.141 P4HTM
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr11_+_122936145 1.131 GRAMD1B
GRAM domain containing 1B
chr3_-_53054999 1.127 SFMBT1
Scm-like with four mbt domains 1
chr4_-_83569572 1.122 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr17_+_6858779 1.111 NM_001142798
NM_001142799
NM_174893
C17orf49


chromosome 17 open reading frame 49


chr17_+_27795633 1.110 PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr3_+_49566901 1.109 NM_003458
BSN
bassoon (presynaptic cytomatrix protein)
chr4_-_83569853 1.097 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr5_-_95323353 1.095 NM_012081
ELL2
elongation factor, RNA polymerase II, 2
chr3_+_106568334 1.092 NM_001627
ALCAM
activated leukocyte cell adhesion molecule
chr12_+_62524778 1.077 NM_020762
SRGAP1
SLIT-ROBO Rho GTPase activating protein 1
chr5_-_95323180 1.071 ELL2
elongation factor, RNA polymerase II, 2
chr17_+_1905104 1.069 NM_006497
HIC1
hypermethylated in cancer 1
chr6_+_71434305 1.066 SMAP1
small ArfGAP 1
chr12_+_52665196 1.062 NM_017409
HOXC10
homeobox C10
chr14_+_64949447 1.059 FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr5_-_127447197 1.053 FLJ33630
hypothetical LOC644873
chr9_-_25668230 1.046 TUSC1
tumor suppressor candidate 1
chr11_+_131285747 1.041 NM_001144058
NM_001144059
NM_016522
NTM


neurotrimin


chr8_+_106400322 1.032 NM_012082
ZFPM2
zinc finger protein, multitype 2
chr5_-_146869811 1.020 NM_001197294
DPYSL3
dihydropyrimidinase-like 3
chr14_+_57932396 1.009 NM_207377
TOMM20L
translocase of outer mitochondrial membrane 20 homolog (yeast)-like
chr6_-_91063301 0.993 NM_001170794
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr11_+_66643311 0.989 NM_012308
KDM2A
lysine (K)-specific demethylase 2A
chr5_-_159478967 0.980 NM_001130864
NM_052927
PWWP2A

PWWP domain containing 2A

chr14_+_37748345 0.978 SSTR1
somatostatin receptor 1
chr10_+_96152175 0.975 NM_015188
TBC1D12
TBC1 domain family, member 12
chr7_-_127833231 0.974 NM_001142573
NM_001142574
NM_001142575
IMPDH1


IMP (inosine 5'-monophosphate) dehydrogenase 1


chr2_-_192767844 0.973 NM_016192
TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr21_+_41461962 0.971 BACE2
beta-site APP-cleaving enzyme 2
chr8_-_108579270 0.960 NM_001146
ANGPT1
angiopoietin 1
chr1_-_153798776 0.947 ASH1L
ash1 (absent, small, or homeotic)-like (Drosophila)
chr11_+_94141151 0.932 NM_130847
AMOTL1
angiomotin like 1
chr1_-_32176275 0.932 PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr3_+_16901455 0.927 NM_001144382
PLCL2
phospholipase C-like 2
chr3_+_154035425 0.925 NM_002563
P2RY1
purinergic receptor P2Y, G-protein coupled, 1
chr5_-_139402989 0.924 NM_001184935
NM_004883
NM_013981
NM_013982
NM_013983
NRG2




neuregulin 2




chr10_-_17536181 0.920 NM_001004470
ST8SIA6
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr9_-_84867604 0.920 RASEF
RAS and EF-hand domain containing
chr5_+_159276317 0.916 NM_000679
ADRA1B
adrenergic, alpha-1B-, receptor
chr5_-_107034484 0.913 NM_001962
EFNA5
ephrin-A5
chr6_-_85530617 0.909 NM_001080508
TBX18
T-box 18
chr1_+_26895108 0.907 NM_006015
NM_139135
ARID1A

AT rich interactive domain 1A (SWI-like)

chr15_-_98699628 0.906 NM_139057
ADAMTS17
ADAM metallopeptidase with thrombospondin type 1 motif, 17
chr1_-_32176562 0.903 NM_080391
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr10_+_52504239 0.901 NM_006258
PRKG1
protein kinase, cGMP-dependent, type I
chr1_-_72521079 0.897


chr12_+_38905053 0.892 NM_198578
LRRK2
leucine-rich repeat kinase 2
chr12_-_68369322 0.884 NM_152439
BEST3
bestrophin 3
chr12_+_56406296 0.882 LOC100130776
hypothetical LOC100130776
chr7_-_11838260 0.882 NM_015204
THSD7A
thrombospondin, type I, domain containing 7A
chr7_+_27190688 0.882


chr16_+_1524162 0.877 NM_024600
TMEM204
transmembrane protein 204
chr5_-_72779585 0.877 FOXD1
forkhead box D1
chr10_-_118021532 0.871 NM_145793
GFRA1
GDNF family receptor alpha 1
chr5_-_146813343 0.870 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr19_+_1022208 0.867 HMHA1
histocompatibility (minor) HA-1
chr4_+_48038095 0.862 SLAIN2
SLAIN motif family, member 2
chr3_+_106568430 0.861 ALCAM
activated leukocyte cell adhesion molecule
chr5_-_146869613 0.860 DPYSL3
dihydropyrimidinase-like 3
chr11_-_10272256 0.859 NM_030962
SBF2
SET binding factor 2
chr1_-_72520735 0.858 NM_173808
NEGR1
neuronal growth regulator 1
chr19_-_60587414 0.855 NM_001190764
LOC388564
hypothetical protein LOC388564
chr9_+_99656013 0.855


chr22_+_47350781 0.852 NM_015381
FAM19A5
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr12_-_48387459 0.850 NM_175736
NM_198900
FMNL3

formin-like 3

chr5_+_66160359 0.849 NM_015183
MAST4
microtubule associated serine/threonine kinase family member 4
chr6_+_45498262 0.841 RUNX2
runt-related transcription factor 2
chr2_+_30223304 0.838 YPEL5
yippee-like 5 (Drosophila)
chr4_+_126457016 0.834 NM_024582
FAT4
FAT tumor suppressor homolog 4 (Drosophila)
chr4_-_111763356 0.834 PITX2
paired-like homeodomain 2
chrX_-_30237403 0.829 NM_000475
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr7_-_19123765 0.827 TWIST1
twist homolog 1 (Drosophila)
chr9_-_109291575 0.824 KLF4
Kruppel-like factor 4 (gut)
chr17_+_27795635 0.817 PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr5_+_113725914 0.815 NM_021614
KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr10_-_17536351 0.813 ST8SIA6
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr7_-_19123787 0.812 NM_000474
TWIST1
twist homolog 1 (Drosophila)
chr3_-_16530132 0.809 NM_015150
RFTN1
raftlin, lipid raft linker 1
chr4_+_3738093 0.808 NM_000683
ADRA2C
adrenergic, alpha-2C-, receptor
chr2_+_30223372 0.806 YPEL5
yippee-like 5 (Drosophila)
chr19_+_54996613 0.805


chr7_+_148613304 0.805 LOC155060
AI894139 pseudogene
chr11_+_131286513 0.805 NTM
neurotrimin
chr1_+_64709063 0.804 NM_020925
CACHD1
cache domain containing 1
chr17_-_39652391 0.802 UBTF
upstream binding transcription factor, RNA polymerase I
chr9_+_966963 0.796 NM_021240
DMRT3
doublesex and mab-3 related transcription factor 3
chr9_-_128924706 0.796 ANGPTL2
angiopoietin-like 2
chr15_-_32875040 0.794 NM_005159
ACTC1
actin, alpha, cardiac muscle 1
chr14_+_103674812 0.793 NM_015656
KIF26A
kinesin family member 26A
chr1_+_120055941 0.789 NM_006623
PHGDH
phosphoglycerate dehydrogenase
chr9_-_5823065 0.789 ERMP1
endoplasmic reticulum metallopeptidase 1
chr10_+_96152262 0.788 TBC1D12
TBC1 domain family, member 12
chr14_+_64949192 0.788 NM_004480
NM_178154
FUT8

fucosyltransferase 8 (alpha (1,6) fucosyltransferase)

chr4_-_122063118 0.787 NM_018699
PRDM5
PR domain containing 5
chrX_+_37315740 0.786 NM_001170331
NM_198511
LANCL3

LanC lantibiotic synthetase component C-like 3 (bacterial)

chr6_+_72653420 0.782 RIMS1
regulating synaptic membrane exocytosis 1
chr9_-_5823072 0.782 NM_024896
ERMP1
endoplasmic reticulum metallopeptidase 1
chr18_+_19523526 0.782 NM_001127717
NM_198129
LAMA3

laminin, alpha 3

chr17_-_959007 0.780 NM_001092
ABR
active BCR-related gene
chr9_-_16717887 0.772 BNC2
basonuclin 2
chr11_-_76800525 0.768 PAK1
p21 protein (Cdc42/Rac)-activated kinase 1
chr3_-_69674412 0.766 FRMD4B
FERM domain containing 4B
chr1_-_32176475 0.764 PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr8_+_27238964 0.760 NM_173176
PTK2B
PTK2B protein tyrosine kinase 2 beta
chr9_-_128924782 0.758 ANGPTL2
angiopoietin-like 2
chr18_-_24011349 0.758 NM_001792
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr5_-_112658200 0.753 MCC
mutated in colorectal cancers
chr14_+_85066265 0.753 FLRT2
fibronectin leucine rich transmembrane protein 2
chr9_-_5822840 0.751 ERMP1
endoplasmic reticulum metallopeptidase 1
chr13_+_100902942 0.750 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr1_+_199108705 0.742 NM_005298
GPR25
G protein-coupled receptor 25

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.27 5.83e-17 GO:0032502 developmental process
1.32 8.47e-17 GO:0048731 system development
1.27 1.47e-15 GO:0007275 multicellular organismal development
1.29 2.13e-15 GO:0048856 anatomical structure development
1.10 2.33e-14 GO:0009987 cellular process
1.41 3.99e-13 GO:0009653 anatomical structure morphogenesis
1.15 6.59e-13 GO:0050794 regulation of cellular process
1.34 9.67e-13 GO:0030154 cell differentiation
1.40 4.92e-12 GO:0007399 nervous system development
1.32 8.58e-12 GO:0048869 cellular developmental process
1.51 1.54e-11 GO:0022008 neurogenesis
1.31 5.23e-11 GO:0048523 negative regulation of cellular process
1.51 1.28e-10 GO:0048699 generation of neurons
1.49 1.34e-10 GO:0048468 cell development
1.13 1.37e-10 GO:0065007 biological regulation
1.13 2.08e-10 GO:0050789 regulation of biological process
1.22 2.96e-10 GO:0023052 signaling
1.28 6.15e-10 GO:0048522 positive regulation of cellular process
1.31 5.72e-09 GO:0006464 protein modification process
1.26 1.24e-08 GO:0044267 cellular protein metabolic process
1.26 2.13e-08 GO:0048519 negative regulation of biological process
1.60 4.09e-08 GO:0000904 cell morphogenesis involved in differentiation
1.24 4.94e-08 GO:0048518 positive regulation of biological process
1.50 5.22e-08 GO:0030182 neuron differentiation
1.56 6.11e-08 GO:0048666 neuron development
1.21 7.18e-08 GO:0007165 signal transduction
1.28 7.75e-08 GO:0043412 macromolecule modification
1.17 1.31e-07 GO:0044260 cellular macromolecule metabolic process
1.60 2.21e-07 GO:0072358 cardiovascular system development
1.60 2.21e-07 GO:0072359 circulatory system development
1.28 3.12e-07 GO:0048513 organ development
1.40 5.57e-07 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.55 6.83e-07 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.61 1.04e-06 GO:0007409 axonogenesis
1.21 1.18e-06 GO:0019538 protein metabolic process
1.59 1.19e-06 GO:0048667 cell morphogenesis involved in neuron differentiation
1.68 1.27e-06 GO:0007411 axon guidance
1.40 1.27e-06 GO:0050793 regulation of developmental process
1.14 1.48e-06 GO:0032501 multicellular organismal process
1.55 1.71e-06 GO:0031175 neuron projection development
1.33 2.41e-06 GO:0051239 regulation of multicellular organismal process
1.58 2.51e-06 GO:0048812 neuron projection morphogenesis
1.29 3.90e-06 GO:0023051 regulation of signaling
1.45 5.28e-06 GO:0045595 regulation of cell differentiation
1.32 5.83e-06 GO:0009893 positive regulation of metabolic process
1.46 6.36e-06 GO:0007167 enzyme linked receptor protein signaling pathway
1.34 7.80e-06 GO:0010604 positive regulation of macromolecule metabolic process
1.46 8.14e-06 GO:0030030 cell projection organization
1.14 9.52e-06 GO:0043170 macromolecule metabolic process
1.46 1.22e-05 GO:0032989 cellular component morphogenesis
1.69 1.27e-05 GO:0001944 vasculature development
1.44 1.46e-05 GO:0010628 positive regulation of gene expression
1.47 1.58e-05 GO:0000902 cell morphogenesis
1.41 3.47e-05 GO:0010557 positive regulation of macromolecule biosynthetic process
1.15 5.00e-05 GO:0051716 cellular response to stimulus
1.44 6.37e-05 GO:0045893 positive regulation of transcription, DNA-dependent
1.37 6.45e-05 GO:0040011 locomotion
1.40 6.93e-05 GO:2000026 regulation of multicellular organismal development
1.37 7.96e-05 GO:0009888 tissue development
1.49 1.01e-04 GO:0048858 cell projection morphogenesis
1.31 1.07e-04 GO:0031325 positive regulation of cellular metabolic process
1.28 1.09e-04 GO:0009966 regulation of signal transduction
1.39 1.10e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.33 1.16e-04 GO:0010646 regulation of cell communication
1.33 1.38e-04 GO:0007154 cell communication
1.66 1.44e-04 GO:0001568 blood vessel development
1.74 1.47e-04 GO:0048514 blood vessel morphogenesis
1.65 1.50e-04 GO:0061061 muscle structure development
1.50 1.74e-04 GO:0048646 anatomical structure formation involved in morphogenesis
1.47 1.96e-04 GO:0032990 cell part morphogenesis
1.60 2.28e-04 GO:0060284 regulation of cell development
1.47 2.30e-04 GO:0007417 central nervous system development
1.36 2.53e-04 GO:0031328 positive regulation of cellular biosynthetic process
1.60 2.81e-04 GO:0022603 regulation of anatomical structure morphogenesis
1.40 3.82e-04 GO:0051254 positive regulation of RNA metabolic process
1.37 4.07e-04 GO:0051173 positive regulation of nitrogen compound metabolic process
1.16 4.40e-04 GO:0016043 cellular component organization
1.16 4.48e-04 GO:0080090 regulation of primary metabolic process
1.35 5.02e-04 GO:0009891 positive regulation of biosynthetic process
1.49 5.08e-04 GO:0023057 negative regulation of signaling
1.15 5.60e-04 GO:0031323 regulation of cellular metabolic process
1.49 6.01e-04 GO:0010648 negative regulation of cell communication
1.19 6.62e-04 GO:0071842 cellular component organization at cellular level
1.31 6.96e-04 GO:0006793 phosphorus metabolic process
1.31 6.96e-04 GO:0006796 phosphate metabolic process
1.50 7.39e-04 GO:0009968 negative regulation of signal transduction
1.38 7.40e-04 GO:0009790 embryo development
1.23 9.38e-04 GO:0007166 cell surface receptor linked signaling pathway
1.16 1.11e-03 GO:0060255 regulation of macromolecule metabolic process
1.49 1.14e-03 GO:0016477 cell migration
1.72 1.38e-03 GO:0007517 muscle organ development
1.42 1.76e-03 GO:0051253 negative regulation of RNA metabolic process
1.85 2.04e-03 GO:0060537 muscle tissue development
1.39 2.45e-03 GO:0009887 organ morphogenesis
1.44 2.72e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.29 2.76e-03 GO:0010941 regulation of cell death
1.29 2.77e-03 GO:0043067 regulation of programmed cell death
1.39 3.11e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.41 3.25e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.15 3.59e-03 GO:0071840 cellular component organization or biogenesis
1.18 3.79e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.29 3.86e-03 GO:0042981 regulation of apoptosis
1.17 3.90e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.17 6.05e-03 GO:0009889 regulation of biosynthetic process
1.25 6.27e-03 GO:0035556 intracellular signal transduction
1.17 6.41e-03 GO:0031326 regulation of cellular biosynthetic process
1.17 7.40e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.13 7.49e-03 GO:0019222 regulation of metabolic process
1.37 7.69e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.16 8.22e-03 GO:0071841 cellular component organization or biogenesis at cellular level
1.34 8.32e-03 GO:0006468 protein phosphorylation
1.29 8.85e-03 GO:0042127 regulation of cell proliferation
1.16 1.11e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.34 1.22e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.64 1.26e-02 GO:0045664 regulation of neuron differentiation
1.36 1.27e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.37 1.31e-02 GO:0010629 negative regulation of gene expression
1.35 1.33e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.09 1.46e-02 GO:0044238 primary metabolic process
1.65 1.53e-02 GO:0043408 regulation of MAPKKK cascade
1.34 1.53e-02 GO:0009890 negative regulation of biosynthetic process
1.42 1.74e-02 GO:0051094 positive regulation of developmental process
1.41 1.81e-02 GO:0048870 cell motility
1.41 1.81e-02 GO:0051674 localization of cell
1.53 1.86e-02 GO:0051960 regulation of nervous system development
1.56 1.92e-02 GO:0000165 MAPKKK cascade
1.81 1.93e-02 GO:0014706 striated muscle tissue development
1.44 2.06e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.39 2.15e-02 GO:0006935 chemotaxis
1.39 2.15e-02 GO:0042330 taxis
1.13 2.39e-02 GO:0051179 localization
1.49 2.45e-02 GO:0001501 skeletal system development
1.56 2.51e-02 GO:0050767 regulation of neurogenesis
1.42 3.07e-02 GO:0008285 negative regulation of cell proliferation
1.31 3.09e-02 GO:0007267 cell-cell signaling
1.52 3.46e-02 GO:0035295 tube development
1.36 3.73e-02 GO:0006928 cellular component movement
1.29 4.33e-02 GO:0016310 phosphorylation
1.37 4.84e-02 GO:0043068 positive regulation of programmed cell death

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.07 2.17e-09 GO:0044424 intracellular part
1.10 1.26e-08 GO:0005737 cytoplasm
1.07 2.84e-08 GO:0005622 intracellular
1.59 4.53e-07 GO:0045202 synapse
1.48 2.69e-04 GO:0043005 neuron projection
1.37 7.00e-04 GO:0030054 cell junction
1.17 3.66e-03 GO:0044459 plasma membrane part
1.06 4.27e-03 GO:0043226 organelle
1.06 5.27e-03 GO:0043229 intracellular organelle
1.49 5.27e-03 GO:0044456 synapse part
1.28 5.80e-03 GO:0005626 insoluble fraction
1.62 8.08e-03 GO:0030424 axon
1.97 8.52e-03 GO:0033267 axon part
1.17 1.06e-02 GO:0005829 cytosol
1.66 1.16e-02 GO:0005912 adherens junction
1.27 1.96e-02 GO:0005624 membrane fraction
1.60 2.17e-02 GO:0070161 anchoring junction
1.09 2.39e-02 GO:0005634 nucleus
1.57 2.46e-02 GO:0031252 cell leading edge
1.03 2.83e-02 GO:0044464 cell part
1.19 2.86e-02 GO:0005856 cytoskeleton
1.03 2.98e-02 GO:0005623 cell
2.24 3.03e-02 GO:0044306 neuron projection terminus
1.13 4.47e-02 GO:0043234 protein complex
1.54 4.59e-02 GO:0030425 dendrite
1.94 4.68e-02 GO:0030427 site of polarized growth

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.15 5.83e-15 GO:0005515 protein binding
1.08 2.16e-11 GO:0005488 binding
1.50 6.46e-09 GO:0043565 sequence-specific DNA binding
1.38 2.17e-07 GO:0030528 transcription regulator activity
1.73 5.20e-05 GO:0000975 regulatory region DNA binding
1.73 5.20e-05 GO:0001067 regulatory region nucleic acid binding
1.73 5.20e-05 GO:0044212 transcription regulatory region DNA binding
1.74 7.77e-05 GO:0010843 promoter binding
1.31 1.60e-04 GO:0001071 nucleic acid binding transcription factor activity
1.31 1.60e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.34 5.82e-04 GO:0019899 enzyme binding
1.48 8.23e-03 GO:0016564 transcription repressor activity
1.95 1.12e-02 GO:0019199 transmembrane receptor protein kinase activity
1.48 1.34e-02 GO:0008134 transcription factor binding
1.46 1.34e-02 GO:0016563 transcription activator activity
1.69 1.98e-02 GO:0005516 calmodulin binding
1.64 2.19e-02 GO:0005085 guanyl-nucleotide exchange factor activity
1.34 2.63e-02 GO:0008092 cytoskeletal protein binding
1.15 3.16e-02 GO:0000166 nucleotide binding
1.36 4.28e-02 GO:0030695 GTPase regulator activity
1.31 4.29e-02 GO:0004672 protein kinase activity
1.17 4.50e-02 GO:0017076 purine nucleotide binding