Motif ID: MTF1.p2

Z-value: 2.158


Transcription factors associated with MTF1.p2:

Gene SymbolEntrez IDGene Name
MTF1 4520 metal-regulatory transcription factor 1



Activity profile for motif MTF1.p2.

activity profile for motif MTF1.p2


Sorted Z-values histogram for motif MTF1.p2

Sorted Z-values for motif MTF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MTF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_-_87535106 5.136 NM_175931
 CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr8_-_143805371 4.215 LOC100288181
hypothetical LOC100288181
chr22_-_30072217 3.857 NM_014323
NM_032050
NM_032051
NM_032052
 PATZ1



POZ (BTB) and AT hook containing zinc finger 1



chr15_+_77511912 3.403 NM_015206
 KIAA1024
KIAA1024
chr22_-_30072329 3.308 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr10_-_128884411 3.028 NM_001039762
 FAM196A
family with sequence similarity 196, member A
chr12_-_56418295 2.984 NM_001122772
 AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr3_+_191714533 2.898 NM_001167928
NM_001167929
NM_001167930
NM_001167931
NM_002182
NM_134470
 IL1RAP





interleukin 1 receptor accessory protein





chr21_+_41461924 2.794 BACE2
beta-site APP-cleaving enzyme 2
chr9_+_90339835 2.773 NM_001161625
NM_145283
 NXNL2

nucleoredoxin-like 2

chr22_-_30071761 2.731 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr13_+_97593469 2.387 FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr13_+_97593411 2.363 NM_001001715
NM_005766
 FARP1

FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)

chr7_-_27136876 2.360 NM_002141
 HOXA4
homeobox A4
chr13_-_100125103 2.358 NM_001079669
NM_032813
 TMTC4

transmembrane and tetratricopeptide repeat containing 4

chr3_+_160964574 2.355 SCHIP1
schwannomin interacting protein 1
chr2_+_207016525 2.335 NM_003812
 ADAM23
ADAM metallopeptidase domain 23
chr3_-_127677451 2.294 NM_001040653
NM_025112
 ZXDC

ZXD family zinc finger C

chr8_-_82186832 2.253 NM_018440
 PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr13_-_25523164 2.233 NM_001007538
 SHISA2
shisa homolog 2 (Xenopus laevis)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 134 entries
enrichment   p-value GO term description
3.54 6.28e-03 GO:0002040 sprouting angiogenesis
2.08 2.90e-03 GO:0060828 regulation of canonical Wnt receptor signaling pathway
2.01 4.63e-05 GO:0030111 regulation of Wnt receptor signaling pathway
2.01 2.58e-02 GO:0050769 positive regulation of neurogenesis
1.98 2.21e-03 GO:0010720 positive regulation of cell development
1.93 7.45e-04 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.91 1.03e-03 GO:0022604 regulation of cell morphogenesis
1.78 4.45e-02 GO:0010975 regulation of neuron projection development
1.76 2.57e-08 GO:0007411 axon guidance
1.74 2.44e-05 GO:0050767 regulation of neurogenesis
1.74 5.07e-04 GO:0045664 regulation of neuron differentiation
1.71 5.85e-10 GO:0048812 neuron projection morphogenesis
1.71 2.12e-09 GO:0007409 axonogenesis
1.70 1.56e-06 GO:0060284 regulation of cell development
1.70 2.22e-05 GO:0051960 regulation of nervous system development
1.70 6.27e-03 GO:0035239 tube morphogenesis
1.68 5.64e-09 GO:0048667 cell morphogenesis involved in neuron differentiation
1.68 1.90e-06 GO:0045597 positive regulation of cell differentiation
1.67 1.44e-03 GO:0002009 morphogenesis of an epithelium
1.66 2.34e-02 GO:0014070 response to organic cyclic compound

Gene overrepresentation in compartment category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
1.73 2.53e-03 GO:0005912 adherens junction
1.61 2.15e-02 GO:0070161 anchoring junction
1.40 1.53e-02 GO:0045202 synapse
1.33 1.37e-02 GO:0030054 cell junction
1.17 6.03e-03 GO:0005829 cytosol
1.17 7.87e-03 GO:0044459 plasma membrane part
1.12 1.46e-11 GO:0005737 cytoplasm
1.09 6.87e-14 GO:0044424 intracellular part
1.09 8.32e-03 GO:0044444 cytoplasmic part
1.08 2.40e-13 GO:0005622 intracellular
1.06 1.45e-03 GO:0043226 organelle
1.06 1.83e-03 GO:0043229 intracellular organelle
1.06 6.42e-03 GO:0043227 membrane-bounded organelle
1.06 7.46e-03 GO:0043231 intracellular membrane-bounded organelle
1.03 6.35e-05 GO:0044464 cell part
1.03 6.77e-05 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
1.94 1.89e-02 GO:0019199 transmembrane receptor protein kinase activity
1.92 9.08e-03 GO:0019887 protein kinase regulator activity
1.87 5.76e-03 GO:0019207 kinase regulator activity
1.73 1.58e-04 GO:0010843 promoter binding
1.70 2.26e-04 GO:0000975 regulatory region DNA binding
1.70 2.26e-04 GO:0001067 regulatory region nucleic acid binding
1.70 2.26e-04 GO:0044212 transcription regulatory region DNA binding
1.50 3.90e-02 GO:0016791 phosphatase activity
1.49 4.96e-03 GO:0016563 transcription activator activity
1.46 8.23e-03 GO:0042578 phosphoric ester hydrolase activity
1.39 1.33e-04 GO:0043565 sequence-specific DNA binding
1.33 2.98e-05 GO:0001071 nucleic acid binding transcription factor activity
1.33 2.98e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.30 3.07e-04 GO:0030528 transcription regulator activity
1.26 2.20e-02 GO:0030234 enzyme regulator activity
1.13 9.09e-11 GO:0005515 protein binding
1.07 1.53e-10 GO:0005488 binding