Motif ID: MYBL2.p2

Z-value: 1.011


Transcription factors associated with MYBL2.p2:

Gene SymbolEntrez IDGene Name
MYBL2 4605 v-myb myeloblastosis viral oncogene homolog (avian)-like 2



Activity profile for motif MYBL2.p2.

activity profile for motif MYBL2.p2


Sorted Z-values histogram for motif MYBL2.p2

Sorted Z-values for motif MYBL2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYBL2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_15814678 1.733 NM_001195098
ANKRD28
ankyrin repeat domain 28
chr11_-_10487212 1.703 NM_001190702
MTRNR2L8
MT-RNR2-like 8
chr10_+_17310263 1.601 NM_003380
VIM
vimentin
chr5_-_79982584 1.465 NM_001190470
MTRNR2L2
MT-RNR2-like 2
chr1_-_197173159 1.414 LOC100131234
familial acute myelogenous leukemia related factor
chr9_-_94338072 1.404 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr5_+_73145098 1.385 RGNEF
190 kDa guanine nucleotide exchange factor
chr17_-_15495534 1.321 TRIM16
tripartite motif containing 16
chr3_-_49372584 1.224 RHOA
ras homolog gene family, member A
chr1_+_143326315 1.143 NM_001037675
NBPF10
NBPF9
NBPF8
neuroblastoma breakpoint family, member 10
neuroblastoma breakpoint family, member 9
neuroblastoma breakpoint family, member 8
chr1_+_557269 1.039


chr1_+_159943385 1.032 NM_001184866
NM_001184867
NM_001184870
NM_001184871
NM_001184872
NM_001184873
NM_032738
FCRLA






Fc receptor-like A






chr3_-_130600931 1.024 RPL32P3
ribosomal protein L32 pseudogene 3
chr5_-_90645974 1.019 LOC100505994
hypothetical LOC100505994
chr1_-_171838802 1.012 NM_178527
SLC9A11
solute carrier family 9, member 11
chr6_+_152053323 0.965 NM_001122742
ESR1
estrogen receptor 1
chr4_-_41579325 0.922


chr12_+_79362256 0.911 NM_001145026
PTPRQ
protein tyrosine phosphatase, receptor type, Q
chr4_+_120276386 0.911 NM_016599
MYOZ2
myozenin 2
chr1_+_146843980 0.889 NM_001102663
NBPF15
NBPF8
NBPF16
neuroblastoma breakpoint family, member 15
neuroblastoma breakpoint family, member 8
neuroblastoma breakpoint family, member 16
chr17_+_21946563 0.854 NM_001190452
MTRNR2L1
MT-RNR2-like 1
chr6_+_53043729 0.807 NM_012347
FBXO9
F-box protein 9
chr11_+_100367929 0.793 NM_032021
TMEM133
transmembrane protein 133
chr3_+_182900081 0.778 SOX2OT
SOX2 overlapping transcript (non-protein coding)
chr3_+_142525744 0.761 NM_001080412
ZBTB38
zinc finger and BTB domain containing 38
chr11_+_111543304 0.741 NM_031275
TEX12
testis expressed 12
chr1_+_172060440 0.736 DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr2_+_138438277 0.735 NM_001024074
NM_001024075
NM_006895
HNMT


histamine N-methyltransferase


chr2_+_151922350 0.734 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr11_+_32994303 0.730 NM_139160
DEPDC7
DEP domain containing 7
chr22_+_42900168 0.730 NM_001137605
PARVG
parvin, gamma
chr7_-_93027057 0.728 NM_001164738
CALCR
calcitonin receptor
chr10_-_69762654 0.723 NM_001033083
NM_022129
PBLD

phenazine biosynthesis-like protein domain containing

chr1_-_208046011 0.705 NM_006147
IRF6
interferon regulatory factor 6
chr11_+_27019084 0.699 NM_003986
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr11_+_20005704 0.694 NAV2
neuron navigator 2
chr10_+_17310475 0.683 VIM
vimentin
chr11_-_123261549 0.672 NM_001013743
TMEM225
transmembrane protein 225
chr1_+_556968 0.660


chr17_-_1195096 0.658 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr7_+_142053693 0.655 NM_001190487
MTRNR2L6
MT-RNR2-like 6
chr3_-_113495763 0.654 NM_183061
SLC9A10
solute carrier family 9, member 10
chr14_-_74669864 0.637 TMED10
transmembrane emp24-like trafficking protein 10 (yeast)
chr10_-_95231933 0.634 NM_013451
NM_133337
MYOF

myoferlin

chr1_-_172060077 0.632 CENPL
centromere protein L
chr15_-_23201740 0.631 NM_130838
UBE3A
ubiquitin protein ligase E3A
chr7_+_28418668 0.626 NM_182898
CREB5
cAMP responsive element binding protein 5
chr2_+_170074457 0.626 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr12_-_14858358 0.625 NM_001013698
C12orf69
chromosome 12 open reading frame 69
chr1_+_226352179 0.619 ARF1
ADP-ribosylation factor 1
chr3_+_14691609 0.618 NM_001184957
NM_001184958
NM_032137
C3orf20


chromosome 3 open reading frame 20


chr1_+_172060563 0.611 DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr5_+_155686750 0.607 SGCD
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr1_-_115102084 0.603 CSDE1
cold shock domain containing E1, RNA-binding
chr16_+_14187965 0.593 MKL2
MKL/myocardin-like 2
chr4_+_38740246 0.592 NM_015990
NM_199039
KLHL5

kelch-like 5 (Drosophila)

chr16_+_55373241 0.587 NUP93
nucleoporin 93kDa
chr10_-_98021144 0.581 NM_001114094
NM_013314
BLNK

B-cell linker

chr1_+_172060389 0.579 NM_018122
DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr1_-_149047329 0.575 NM_000396
CTSK
cathepsin K
chr1_+_149877955 0.574 SNX27
sorting nexin family member 27
chr15_-_40537002 0.567 NM_022473
ZFP106
zinc finger protein 106 homolog (mouse)
chr9_+_122923864 0.567 CEP110
centrosomal protein 110kDa
chr1_+_171871283 0.562 NM_001195190
LOC730159
hypothetical protein LOC730159
chr12_-_119733062 0.557 SPPL3
signal peptide peptidase 3
chr20_+_36408237 0.554 NM_004139
LBP
lipopolysaccharide binding protein
chr14_+_102871740 0.553 EIF5
eukaryotic translation initiation factor 5
chr10_-_98315090 0.553 TM9SF3
transmembrane 9 superfamily member 3
chr1_+_559618 0.548


chr6_+_45404031 0.546 NM_001015051
NM_001024630
RUNX2

runt-related transcription factor 2

chr7_+_129771865 0.546 NM_001127441
NM_001127442
NM_080385
CPA5


carboxypeptidase A5


chr12_-_48902692 0.542 NM_001113547
LIMA1
LIM domain and actin binding 1
chr12_-_69317441 0.540 NM_001109754
PTPRB
protein tyrosine phosphatase, receptor type, B
chr12_+_49922592 0.531 DAZAP2
DAZ associated protein 2
chr16_+_24475129 0.527 RBBP6
retinoblastoma binding protein 6
chr1_+_35623688 0.525 ZMYM4
zinc finger, MYM-type 4
chr1_+_50344550 0.521 NM_001144775
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr11_-_35503720 0.521 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr4_-_39199527 0.518 UGDH
UDP-glucose 6-dehydrogenase
chr14_+_64523700 0.513


chr4_+_3341521 0.513 NM_198227
RGS12
regulator of G-protein signaling 12
chr15_+_47502666 0.512 NM_002009
FGF7
fibroblast growth factor 7
chr12_+_381001 0.508 NM_001130146
NM_032358
CCDC77

coiled-coil domain containing 77

chr12_+_32578513 0.503 FGD4
FYVE, RhoGEF and PH domain containing 4
chr17_+_3065661 0.496 NM_014565
OR1A1
olfactory receptor, family 1, subfamily A, member 1
chr22_+_38903825 0.496 NM_001162501
NM_015088
TNRC6B

trinucleotide repeat containing 6B

chr1_-_115102106 0.495 CSDE1
cold shock domain containing E1, RNA-binding
chr7_+_28497272 0.494 CREB5
cAMP responsive element binding protein 5
chr10_+_90414125 0.486 NM_001198828
NM_001198829
NM_001198830
NM_004190
LIPF



lipase, gastric



chr8_+_110168828 0.485 NM_003301
TRHR
thyrotropin-releasing hormone receptor
chr1_+_173111306 0.482 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr12_-_9804682 0.477 NM_001781
CD69
CD69 molecule
chr1_-_42157077 0.471 NM_001127714
NM_024503
HIVEP3

human immunodeficiency virus type I enhancer binding protein 3

chr12_+_55201854 0.471 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr10_-_32707549 0.464 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr12_+_94200306 0.461 VEZT
vezatin, adherens junctions transmembrane protein
chr1_-_115102109 0.457 CSDE1
cold shock domain containing E1, RNA-binding
chr12_+_14429499 0.457 ATF7IP
activating transcription factor 7 interacting protein
chr1_-_115102124 0.457 CSDE1
cold shock domain containing E1, RNA-binding
chr9_+_106496480 0.456 NM_001004484
OR13D1
olfactory receptor, family 13, subfamily D, member 1
chr6_-_112186977 0.452 NM_153048
FYN
FYN oncogene related to SRC, FGR, YES
chr20_+_58146916 0.452 LOC284757
hypothetical protein LOC284757
chr12_-_101115677 0.450 NM_002674
PMCH
pro-melanin-concentrating hormone
chr1_+_559129 0.449


chr13_-_48873735 0.448 NM_030925
CAB39L
calcium binding protein 39-like
chr15_+_55298908 0.447 NM_207040
TCF12
transcription factor 12
chr6_+_126143971 0.443 NCOA7
nuclear receptor coactivator 7
chr6_-_169392771 0.442


chr1_-_166149867 0.440 NM_001167749
NM_018417
ADCY10

adenylate cyclase 10 (soluble)

chr17_-_70901303 0.438 GRB2
growth factor receptor-bound protein 2
chr12_-_38300109 0.437 NM_005164
ABCD2
ATP-binding cassette, sub-family D (ALD), member 2
chr5_+_132456293 0.433 HSPA4
heat shock 70kDa protein 4
chr11_+_65024889 0.431 MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr6_-_33016561 0.430 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr3_+_142175329 0.429 SLC25A36
solute carrier family 25, member 36
chr1_-_21373816 0.429 NM_001198803
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr21_-_29179482 0.429 NM_013240
NM_182749
N6AMT1

N-6 adenine-specific DNA methyltransferase 1 (putative)

chr3_+_142569988 0.427 ZBTB38
zinc finger and BTB domain containing 38
chr9_-_72219359 0.426 NM_001206
KLF9
Kruppel-like factor 9
chr1_-_110735158 0.425 NM_004696
SLC16A4
solute carrier family 16, member 4 (monocarboxylic acid transporter 5)
chr11_-_104332631 0.423 NM_033306
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr7_+_50106227 0.422 NM_001161834
C7orf72
chromosome 7 open reading frame 72
chrX_+_130505630 0.421 NM_001004486
OR13H1
olfactory receptor, family 13, subfamily H, member 1
chr4_-_151993422 0.418


chr17_-_16038607 0.415 NM_001190438
NM_001190440
NCOR1

nuclear receptor corepressor 1

chr14_+_66901237 0.410 EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr12_+_100512877 0.408 NM_002465
NM_206819
NM_206820
NM_206821
MYBPC1



myosin binding protein C, slow type



chr13_-_59223074 0.408


chr11_-_5321329 0.407 NM_001005567
OR51B5
olfactory receptor, family 51, subfamily B, member 5
chr1_-_157551072 0.407 NM_001004467
OR10J3
olfactory receptor, family 10, subfamily J, member 3
chr5_-_94443300 0.406 NM_001002796
MCTP1
multiple C2 domains, transmembrane 1
chr13_-_19244398 0.403 PSPC1
paraspeckle component 1
chr3_-_27473248 0.403 NM_003615
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr17_+_46176105 0.403 LUC7L3
LUC7-like 3 (S. cerevisiae)
chrX_-_19598912 0.400 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr4_-_184480572 0.395 NM_001185149
CLDN24
claudin 24
chr9_-_5958367 0.395


chr12_-_16649211 0.384 LMO3
LIM domain only 3 (rhombotin-like 2)
chr2_-_73346215 0.382 FBXO41
F-box protein 41
chr4_-_47709717 0.381 NM_000087
CNGA1
cyclic nucleotide gated channel alpha 1
chr9_+_124551839 0.381 NM_001004453
OR1L6
olfactory receptor, family 1, subfamily L, member 6
chr13_+_75232797 0.376 NM_015842
LMO7
LIM domain 7
chr1_+_20269239 0.375 NM_000929
PLA2G5
phospholipase A2, group V
chr6_-_46155937 0.369 NM_001114086
CLIC5
chloride intracellular channel 5
chr1_+_108794426 0.368 NM_001143987
NM_001143988
NBPF4
NBPF6

neuroblastoma breakpoint family, member 4
neuroblastoma breakpoint family, member 6

chr1_+_147006065 0.366 NM_001102663
NBPF15
NBPF8
NBPF16
neuroblastoma breakpoint family, member 15
neuroblastoma breakpoint family, member 8
neuroblastoma breakpoint family, member 16
chr2_-_40510923 0.363 NM_001112800
NM_001112801
NM_021097
SLC8A1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr11_+_54867202 0.360 NM_001005274
OR4A16
olfactory receptor, family 4, subfamily A, member 16
chr7_-_23020199 0.360 FAM126A
family with sequence similarity 126, member A
chr17_-_55958274 0.357 NM_006380
APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr1_-_42156913 0.357


chr1_-_42156957 0.354 HIVEP3
human immunodeficiency virus type I enhancer binding protein 3
chr1_-_120189301 0.354 NM_001047980
NBPF7
neuroblastoma breakpoint family, member 7
chr1_-_143708467 0.352 NM_001195260
PDE4DIP
phosphodiesterase 4D interacting protein
chr9_+_5646582 0.350 NM_020829
KIAA1432
KIAA1432
chr2_-_36929520 0.350 STRN
striatin, calmodulin binding protein
chr7_+_93388951 0.349 NM_004126
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr2_-_10860093 0.347 PDIA6
protein disulfide isomerase family A, member 6
chr2_+_165804157 0.345 NM_001040142
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr8_-_17599438 0.344 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr1_-_115102138 0.342 NM_001007553
NM_007158
NM_001130523
CSDE1


cold shock domain containing E1, RNA-binding


chr11_-_8911110 0.340 NM_020643
C11orf16
chromosome 11 open reading frame 16
chr3_+_29297806 0.339 NM_001003792
NM_001003793
NM_001177711
NM_001177712
NM_014483
RBMS3




RNA binding motif, single stranded interacting protein 3




chrX_+_74410774 0.338


chr3_+_189413414 0.337 NM_005578
LPP
LIM domain containing preferred translocation partner in lipoma
chr9_-_99740243 0.335 NM_197978
HEMGN
hemogen
chr15_+_65205107 0.334 NM_001145102
SMAD3
SMAD family member 3
chrX_-_102396704 0.331 NM_001006684
NM_153333
TCEAL8

transcription elongation factor A (SII)-like 8

chr2_-_198248828 0.331 NM_144629
RFTN2
raftlin family member 2
chr1_-_93172119 0.330


chr11_-_4675524 0.329 NM_030774
OR51E2
olfactory receptor, family 51, subfamily E, member 2
chr1_+_239762179 0.328 NM_003679
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr1_-_103269356 0.325 COL11A1
collagen, type XI, alpha 1
chr18_+_70471906 0.324 NM_001146189
NM_001146190
NM_017757
ZNF407


zinc finger protein 407


chr1_-_108588186 0.323 NM_001143989
NBPF4
NBPF6
neuroblastoma breakpoint family, member 4
neuroblastoma breakpoint family, member 6
chr3_+_45902999 0.322 NM_006641
NM_031200
CCR9

chemokine (C-C motif) receptor 9

chr9_+_119506446 0.321 TLR4
toll-like receptor 4
chr9_+_78246401 0.318 NM_001097634
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr11_+_18374388 0.318 NM_001165414
LDHA
lactate dehydrogenase A
chr9_+_119506428 0.317 TLR4
toll-like receptor 4
chr17_+_45221118 0.317 MYST2
MYST histone acetyltransferase 2
chr2_-_169596078 0.316 NM_003742
ABCB11
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr8_+_32905027 0.315


chr17_-_36587965 0.314 NM_033062
KRTAP4-2
keratin associated protein 4-2
chr10_+_35524835 0.313 NM_182721
NM_182722
NM_182723
NM_182724
NM_182725
CREM




cAMP responsive element modulator




chr4_-_148086413 0.313 NM_031956
TTC29
tetratricopeptide repeat domain 29
chr4_+_69996780 0.312 NM_001074
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr1_-_150398327 0.312 NM_001122965
RPTN
repetin
chr2_-_189752575 0.312 NM_000393
COL5A2
collagen, type V, alpha 2
chr12_+_21175394 0.311 NM_006446
SLCO1B1
solute carrier organic anion transporter family, member 1B1
chr4_-_122357104 0.311 NM_001128843
TNIP3
TNFAIP3 interacting protein 3
chr6_-_24827265 0.311 NM_030939
C6orf62
chromosome 6 open reading frame 62
chr3_-_56673113 0.310 NM_015224
C3orf63
chromosome 3 open reading frame 63
chrX_+_51562894 0.310 NM_001005332
MAGED1
melanoma antigen family D, 1
chr7_-_111216180 0.310 DOCK4
dedicator of cytokinesis 4
chr4_+_123380569 0.306 KIAA1109
KIAA1109
chr11_-_85107569 0.304 NM_206929
SYTL2
synaptotagmin-like 2
chr12_+_118515646 0.302 NM_001136534
TMEM233
transmembrane protein 233
chr8_-_10550026 0.302 NM_178857
RP1L1
retinitis pigmentosa 1-like 1
chr11_+_64950074 0.299 NEAT1
nuclear paraspeckle assembly transcript 1 (non-protein coding)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.55 4.04e-03 GO:0003008 system process
2.19 6.41e-03 GO:0007608 sensory perception of smell
2.01 3.98e-02 GO:0007606 sensory perception of chemical stimulus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.30 1.51e-03 GO:0071944 cell periphery
1.29 2.31e-03 GO:0005886 plasma membrane
3.32 2.37e-03 GO:0030016 myofibril
3.14 5.43e-03 GO:0043292 contractile fiber
3.03 2.37e-02 GO:0044449 contractile fiber part

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.24 1.15e-03 GO:0004984 olfactory receptor activity