Motif ID: MZF1.p2

Z-value: 2.669


Transcription factors associated with MZF1.p2:

Gene SymbolEntrez IDGene Name
MZF1 7593 myeloid zinc finger 1



Activity profile for motif MZF1.p2.

activity profile for motif MZF1.p2


Sorted Z-values histogram for motif MZF1.p2

Sorted Z-values for motif MZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MZF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_108665168 7.560 NM_021224
 ZNF462
zinc finger protein 462
chr18_-_22382497 6.039 NM_001142730
 KCTD1
potassium channel tetramerisation domain containing 1
chr8_+_22513043 4.099 NM_001013842
NM_001198827
NM_173686
 C8orf58


chromosome 8 open reading frame 58


chr13_+_113574925 3.963 NM_001143945
 GAS6
growth arrest-specific 6
chr10_-_105604942 3.596 NM_014631
 SH3PXD2A
SH3 and PX domains 2A
chr4_-_158111916 3.079 PDGFC
platelet derived growth factor C
chr13_-_39075200 3.011 LHFP
lipoma HMGIC fusion partner
chr4_-_158111995 2.977 NM_016205
 PDGFC
platelet derived growth factor C
chr4_-_11039600 2.940 NM_005114
 HS3ST1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chrX_-_1291526 2.929 NM_001012288
NM_022148
 CRLF2

cytokine receptor-like factor 2

chr15_+_66658626 2.517 NM_006091
 CORO2B
coronin, actin binding protein, 2B
chr5_+_17270474 2.433 NM_006317
 BASP1
brain abundant, membrane attached signal protein 1
chr7_-_27136876 2.373 NM_002141
 HOXA4
homeobox A4
chr1_-_72521079 2.347


chr21_-_27261276 2.335 NM_007038
 ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr11_-_68537243 2.332 NM_001098515
NM_145015
 MRGPRF

MAS-related GPR, member F

chr13_-_43259032 2.183 NM_017993
 ENOX1
ecto-NOX disulfide-thiol exchanger 1
chr5_+_92944680 2.177 NM_005654
 NR2F1
nuclear receptor subfamily 2, group F, member 1
chr11_+_61352209 2.158 NM_004265
 FADS2
fatty acid desaturase 2
chr6_-_10523203 2.157 TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 219 entries
enrichment   p-value GO term description
1.92 3.30e-03 GO:0048738 cardiac muscle tissue development
1.80 1.12e-02 GO:0001657 ureteric bud development
1.77 3.68e-02 GO:0042326 negative regulation of phosphorylation
1.72 1.26e-04 GO:0014706 striated muscle tissue development
1.70 5.41e-05 GO:0060537 muscle tissue development
1.69 1.01e-02 GO:0030278 regulation of ossification
1.68 4.49e-03 GO:0001822 kidney development
1.67 3.12e-02 GO:0030326 embryonic limb morphogenesis
1.67 3.12e-02 GO:0035113 embryonic appendage morphogenesis
1.64 1.02e-02 GO:0072001 renal system development
1.63 4.19e-04 GO:0001655 urogenital system development
1.61 4.99e-02 GO:0035107 appendage morphogenesis
1.61 4.99e-02 GO:0035108 limb morphogenesis
1.60 2.43e-07 GO:0030036 actin cytoskeleton organization
1.60 1.34e-05 GO:0044087 regulation of cellular component biogenesis
1.59 2.74e-02 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
1.57 6.40e-06 GO:0051129 negative regulation of cellular component organization
1.57 3.11e-03 GO:0030335 positive regulation of cell migration
1.57 3.11e-03 GO:2000147 positive regulation of cell motility
1.57 5.41e-03 GO:0045165 cell fate commitment

Gene overrepresentation in compartment category:

Showing 1 to 20 of 44 entries
enrichment   p-value GO term description
2.09 1.72e-02 GO:0032432 actin filament bundle
2.07 9.10e-03 GO:0042641 actomyosin
2.00 5.66e-03 GO:0000781 chromosome, telomeric region
1.92 2.33e-02 GO:0043679 axon terminus
1.90 2.36e-02 GO:0044306 neuron projection terminus
1.79 1.66e-05 GO:0005925 focal adhesion
1.73 7.80e-05 GO:0005924 cell-substrate adherens junction
1.72 6.97e-05 GO:0030055 cell-substrate junction
1.65 3.16e-02 GO:0033267 axon part
1.55 8.63e-04 GO:0005912 adherens junction
1.49 4.19e-05 GO:0016323 basolateral plasma membrane
1.47 4.14e-03 GO:0031252 cell leading edge
1.47 8.27e-03 GO:0070161 anchoring junction
1.46 1.50e-02 GO:0030136 clathrin-coated vesicle
1.43 1.77e-02 GO:0030424 axon
1.41 3.45e-06 GO:0045202 synapse
1.41 1.78e-02 GO:0030135 coated vesicle
1.39 8.92e-04 GO:0044456 synapse part
1.37 1.00e-04 GO:0043005 neuron projection
1.37 3.94e-03 GO:0015629 actin cytoskeleton

Gene overrepresentation in function category:

Showing 1 to 20 of 20 entries
enrichment   p-value GO term description
1.48 1.30e-03 GO:0010843 promoter binding
1.47 1.79e-03 GO:0000975 regulatory region DNA binding
1.47 1.79e-03 GO:0001067 regulatory region nucleic acid binding
1.47 1.79e-03 GO:0044212 transcription regulatory region DNA binding
1.46 3.27e-06 GO:0003779 actin binding
1.43 2.70e-12 GO:0043565 sequence-specific DNA binding
1.40 8.44e-04 GO:0008134 transcription factor binding
1.38 3.62e-07 GO:0008092 cytoskeletal protein binding
1.35 6.95e-03 GO:0016563 transcription activator activity
1.34 4.82e-12 GO:0030528 transcription regulator activity
1.34 2.01e-11 GO:0001071 nucleic acid binding transcription factor activity
1.34 2.01e-11 GO:0003700 sequence-specific DNA binding transcription factor activity
1.33 4.70e-03 GO:0000988 protein binding transcription factor activity
1.33 4.70e-03 GO:0000989 transcription factor binding transcription factor activity
1.32 1.49e-03 GO:0019904 protein domain specific binding
1.32 6.33e-03 GO:0003712 transcription cofactor activity
1.26 3.79e-04 GO:0019899 enzyme binding
1.14 8.87e-23 GO:0005515 protein binding
1.13 5.70e-03 GO:0003677 DNA binding
1.07 2.69e-17 GO:0005488 binding