Motif ID: NANOG.p2

Z-value: 0.861


Transcription factors associated with NANOG.p2:

Gene SymbolEntrez IDGene Name
NANOG 79923 Nanog homeobox



Activity profile for motif NANOG.p2.

activity profile for motif NANOG.p2


Sorted Z-values histogram for motif NANOG.p2

Sorted Z-values for motif NANOG.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NANOG.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_177106702 1.356 NM_004673
ANGPTL1
angiopoietin-like 1
chr14_+_100365162 1.313 MEG3
maternally expressed 3 (non-protein coding)
chrX_+_28515479 1.265 NM_014271
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr7_-_13996166 1.205 NM_001163147
NM_004956
ETV1

ets variant 1

chr2_-_144994038 1.077 ZEB2
zinc finger E-box binding homeobox 2
chr2_-_110665188 1.043 NM_033514
LIMS3-LOC440895
LIMS3
LIMS3-LOC440895 read-through
LIM and senescent cell antigen-like domains 3
chr4_+_114190233 0.928 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr9_+_117955890 0.916 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr5_+_176744037 0.889 NM_001167579
NM_003052
SLC34A1

solute carrier family 34 (sodium phosphate), member 1

chr4_-_186815116 0.884 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr9_-_8723893 0.881 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chr1_+_168898898 0.865 PRRX1
paired related homeobox 1
chr16_+_51690564 0.839 CHD9
chromodomain helicase DNA binding protein 9
chr21_-_30836051 0.823 NM_181612
KRTAP19-6
keratin associated protein 19-6
chr5_+_155686333 0.791 NM_000337
NM_001128209
NM_172244
SGCD


sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)


chr13_+_100902942 0.739 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr3_+_161040343 0.698 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr3_+_116824840 0.689 NM_001130064
NM_002045
GAP43

growth associated protein 43

chr4_-_138673014 0.671 PCDH18
protocadherin 18
chr4_+_114433551 0.647 ANK2
ankyrin 2, neuronal

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 29 entries
enrichment   p-value GO term description
5.78 3.54e-02 GO:0051149 positive regulation of muscle cell differentiation
3.84 9.07e-04 GO:0001503 ossification
3.77 5.51e-06 GO:0007517 muscle organ development
3.39 2.10e-02 GO:0060537 muscle tissue development
3.27 4.01e-06 GO:0061061 muscle structure development
3.03 3.27e-02 GO:0030155 regulation of cell adhesion
2.53 8.67e-03 GO:0060284 regulation of cell development
2.42 2.14e-02 GO:0045597 positive regulation of cell differentiation
2.39 2.01e-06 GO:0045595 regulation of cell differentiation
2.20 2.25e-02 GO:0051094 positive regulation of developmental process
2.13 6.05e-06 GO:0050793 regulation of developmental process
2.05 1.19e-04 GO:0009888 tissue development
2.05 9.42e-04 GO:2000026 regulation of multicellular organismal development
1.74 3.10e-06 GO:0048513 organ development
1.69 8.89e-03 GO:0051239 regulation of multicellular organismal process
1.61 2.44e-04 GO:0030154 cell differentiation
1.61 1.68e-02 GO:0009653 anatomical structure morphogenesis
1.59 5.37e-03 GO:0003008 system process
1.59 3.49e-02 GO:0007399 nervous system development
1.58 5.88e-04 GO:0048869 cellular developmental process

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.45 1.08e-02 GO:0005576 extracellular region
1.31 4.57e-03 GO:0005886 plasma membrane
1.30 5.31e-03 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.94 2.94e-03 GO:0043565 sequence-specific DNA binding
1.81 8.01e-04 GO:0001071 nucleic acid binding transcription factor activity
1.81 8.01e-04 GO:0003700 sequence-specific DNA binding transcription factor activity