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Motif ID: NFE2L2.p2

Z-value: 2.356

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr22_+_21484240	6.020
chr22_+_21340757	5.504
chr22_+_21094094	4.633
chr22_+_21393107	3.850		IGLJ3	immunoglobulin lambda joining 3
chr22_+_21079355	3.840
chr22_+_21359175	3.797		IGLV3-25	immunoglobulin lambda variable 3-25
chr22_+_21370394	3.556		IGL@	immunoglobulin lambda locus
chr22_+_21065202	3.135
chr22_+_21065207	3.098		IGLJ3	immunoglobulin lambda joining 3
chr22_+_21065134	3.074		LOC100290481	immunoglobulin lambda light chain-like
chr22_+_21053972	2.703
chr22_+_21407066	2.524
chr14_-_105712630	2.437		IGHV4-31 IGHA1 IGHA2 IGHG1	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant alpha 2 (A2m marker) immunoglobulin heavy constant gamma 1 (G1m marker)
chr22_+_20316968	2.368	NM_152612	CCDC116	coiled-coil domain containing 116
chr14_-_105804211	2.287		IGHG1	immunoglobulin heavy constant gamma 1 (G1m marker)
chr22_+_21042091	2.231		IGLV1-44 IGL@	immunoglobulin lambda variable 1-44 immunoglobulin lambda locus
chr10_-_76538859	2.183	NM_001007271 NM_001007272 NM_001007273	DUSP13	dual specificity phosphatase 13
chr22_+_20899155	2.180
chr4_-_977163	2.147	NM_022042 NM_134425 NM_213613	SLC26A1	solute carrier family 26 (sulfate transporter), member 1
chr12_+_54361685	2.086		METTL7B	methyltransferase like 7B
chr8_-_11242408	2.053		LOC100129129	hypothetical LOC100129129
chr12_+_54361596	2.047	NM_152637	METTL7B	methyltransferase like 7B
chr22_+_21116283	1.988
chr20_+_2744947	1.933	NM_001167670	LOC100288797	hypothetical protein LOC100288797
chr22_+_18388656	1.832		C22orf25	chromosome 22 open reading frame 25
chr6_-_32121784	1.823	NM_032470	TNXB	tenascin XB
chr1_+_17571277	1.782	NM_207421	PADI6	peptidyl arginine deiminase, type VI
chr7_+_139175420	1.734	NM_001061 NM_001166253 NM_030984	TBXAS1	thromboxane A synthase 1 (platelet)
chr14_+_19365447	1.683	NM_001004723	OR4N2	olfactory receptor, family 4, subfamily N, member 2
chr22_+_21559959	1.609	NM_001178126	IGLL5 IGLC1	immunoglobulin lambda-like polypeptide 5 immunoglobulin lambda constant 1 (Mcg marker)
chr9_+_129962292	1.605	NM_024112	C9orf16	chromosome 9 open reading frame 16
chr6_-_31853027	1.573	NM_025258	C6orf27	chromosome 6 open reading frame 27
chr3_-_46582806	1.571	NM_024512	LRRC2	leucine rich repeat containing 2
chr22_+_21011653	1.567
chr22_+_21495273	1.519
chr22_+_21552897	1.515		LOC100290481	immunoglobulin lambda light chain-like
chr14_+_19681734	1.495	NM_001004724	OR4N5	olfactory receptor, family 4, subfamily N, member 5
chr22_+_19699441	1.459	NM_001159554 NM_005446	P2RX6	purinergic receptor P2X, ligand-gated ion channel, 6
chr6_+_32229599	1.438	NM_005155	PPT2-EGFL8 PPT2	PPT2-EGFL8 read-through transcript palmitoyl-protein thioesterase 2
chr17_+_77910411	1.396	NM_207459	TEX19	testis expressed 19
chr6_+_44322831	1.394		HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1
chr14_-_105862080	1.377		IGHV4-31 IGHA1 IGHD IGHG1 IGHG2 IGHG3 IGHM SCFV	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 2 (G2m marker) immunoglobulin heavy constant gamma 3 (G3m marker) immunoglobulin heavy constant mu single-chain Fv fragment
chr19_-_54350457	1.377	NM_002152	HRC	histidine rich calcium binding protein
chr12_-_51629874	1.363		KRT8	keratin 8
chr22_+_20880159	1.324		IGLV6-57	immunoglobulin lambda variable 6-57
chr6_+_44322764	1.315	NM_007355	HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1
chr6_+_32229278	1.305	NM_138717	PPT2	palmitoyl-protein thioesterase 2
chr5_+_140594121	1.303		PCDHB18	protocadherin beta 18 pseudogene
chr14_-_106084085	1.235		IGHV4-31 IGHG1	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant gamma 1 (G1m marker)
chr16_+_82544327	1.235	NM_182981	OSGIN1	oxidative stress induced growth inhibitor 1
chr16_-_1369613	1.225	NM_001193389 NM_023076	UNKL	unkempt homolog (Drosophila)-like
chr16_-_28528780	1.224	NM_001055 NM_177529	SULT1A1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr3_-_195571748	1.215	NM_001135057 NM_130830	LRRC15	leucine rich repeat containing 15
chr17_+_71109734	1.197		MYO15B	myosin XVB pseudogene
chr4_+_22608252	1.171
chr14_-_95011790	1.168	NM_152592	C14orf49	chromosome 14 open reading frame 49
chr7_+_72883128	1.162	NM_001305	CLDN4	claudin 4
chr11_+_66764064	1.155		KDM2A	lysine (K)-specific demethylase 2A
chr14_-_106084519	1.141		IGHA1 IGHG1	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker)
chr18_+_148480	1.122	NM_001037334 NM_005151	USP14	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
chr8_-_145097031	1.118	NM_201380	PLEC	plectin
chr12_-_51585004	1.094	NM_002273	KRT8	keratin 8
chr6_-_29563657	1.091	NM_052967	MAS1L	MAS1 oncogene-like
chr1_+_27591738	1.078	NM_005281	GPR3	G protein-coupled receptor 3
chr7_+_111850367	1.074	NM_001007245 NM_001197080	IFRD1	interferon-related developmental regulator 1
chr9_-_139042526	1.061	NM_001606	ABCA2	ATP-binding cassette, sub-family A (ABC1), member 2
chr22_-_17846711	1.051		UFD1L	ubiquitin fusion degradation 1 like (yeast)
chr6_+_36518778	1.051		KCTD20	potassium channel tetramerisation domain containing 20
chr6_-_33655995	1.036	NM_001188	BAK1	BCL2-antagonist/killer 1
chr19_-_53914768	1.032	NM_001130915	MAMSTR	MEF2 activating motif and SAP domain containing transcriptional regulator
chr1_-_156784518	1.030	NM_001005189	OR6Y1	olfactory receptor, family 6, subfamily Y, member 1
chr22_+_43451600	1.028		PRR5	proline rich 5 (renal)
chr6_+_150112537	1.026		PCMT1	protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr11_-_66898223	1.012	NM_001166212	CLCF1	cardiotrophin-like cytokine factor 1
chr6_-_33655811	1.011		BAK1	BCL2-antagonist/killer 1
chr22_-_17846725	1.008	NM_001035247 NM_005659	UFD1L	ubiquitin fusion degradation 1 like (yeast)
chr16_+_72888161	1.004	NM_002811	PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr16_+_88696172	0.994		FAM157C	family with sequence similarity 157, member C
chr11_+_66764060	0.984		LOC100131150	hypothetical protein LOC100131150
chr22_-_17846621	0.980		UFD1L	ubiquitin fusion degradation 1 like (yeast)
chr19_-_56260135	0.969	NM_015596	KLK13	kallikrein-related peptidase 13
chr18_+_148586	0.961		USP14	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
chr19_-_40696393	0.942	NM_001126056 NM_001126057 NM_001126058 NM_001190347 NM_001190348 NM_001190349 NM_033317	DMKN	dermokine
chr2_+_161873031	0.940	NM_005805	PSMD14	proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
chrX_-_100527799	0.939	NM_000061	BTK	Bruton agammaglobulinemia tyrosine kinase
chr1_-_6585268	0.925		KLHL21	kelch-like 21 (Drosophila)
chr1_-_199259447	0.917	NM_017596	KIF21B	kinesin family member 21B
chr9_-_139202855	0.914	NM_013366	ANAPC2	anaphase promoting complex subunit 2
chr16_+_30326864	0.903		ZNF771	zinc finger protein 771
chr1_+_3378030	0.895		ARHGEF16	Rho guanine nucleotide exchange factor (GEF) 16
chr9_+_139202874	0.884	NM_003731	SSNA1	Sjogren syndrome nuclear autoantigen 1
chr20_+_41621119	0.878		SGK2	serum/glucocorticoid regulated kinase 2
chr1_-_45760115	0.872	NM_002574 NM_181696 NM_181697	PRDX1	peroxiredoxin 1
chr19_-_43926953	0.869	NM_144691	CAPN12	calpain 12
chr16_-_30032330	0.866	NM_024307	GDPD3	glycerophosphodiester phosphodiesterase domain containing 3
chr9_-_139202804	0.857		ANAPC2	anaphase promoting complex subunit 2
chr9_-_139202831	0.852		ANAPC2	anaphase promoting complex subunit 2
chr15_-_62173041	0.848	NM_001014812 NM_032231	FAM96A	family with sequence similarity 96, member A
chr8_-_144887876	0.840	NM_198488	FAM83H	family with sequence similarity 83, member H
chr7_-_75280962	0.835	NM_002991	CCL24	chemokine (C-C motif) ligand 24
chr6_+_31782618	0.829	NM_001003693	LY6G6F	lymphocyte antigen 6 complex, locus G6F
chr20_+_41621079	0.827	NM_170693	SGK2	serum/glucocorticoid regulated kinase 2
chr17_-_43254132	0.815	NM_145798	OSBPL7	oxysterol binding protein-like 7
chr6_+_34314545	0.815	NM_145905	HMGA1	high mobility group AT-hook 1
chr16_-_28528149	0.813	NM_177530 NM_177534	SULT1A1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr17_-_43254117	0.810		OSBPL7	oxysterol binding protein-like 7
chr10_-_73280964	0.805		PSAP	prosaposin
chr10_-_73281047	0.805		PSAP	prosaposin
chr2_+_161873190	0.801		PSMD14	proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
chr1_-_199259133	0.794		KIF21B	kinesin family member 21B
chr16_+_72888231	0.793		PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr6_-_170704251	0.793		PSMB1	proteasome (prosome, macropain) subunit, beta type, 1
chr9_-_139042416	0.775		ABCA2	ATP-binding cassette, sub-family A (ABC1), member 2
chr21_-_35181956	0.774		RUNX1	runt-related transcription factor 1
chr22_+_21006814	0.769
chr6_-_28999621	0.756		TRIM27	tripartite motif containing 27
chr16_+_30326077	0.755	NM_001142305 NM_016643	ZNF771	zinc finger protein 771
chr6_+_44302973	0.754		SLC29A1	solute carrier family 29 (nucleoside transporters), member 1
chr6_+_150112511	0.748	NM_005389	PCMT1	protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr3_+_122794859	0.747	NM_016298	FBXO40	F-box protein 40
chr19_-_51820133	0.744	NM_000960	PTGIR	prostaglandin I2 (prostacyclin) receptor (IP)
chr10_+_134751398	0.738	NM_001083909	GPR123	G protein-coupled receptor 123
chr22_+_20880112	0.732
chr16_+_65869558	0.729	NM_001129727	PLEKHG4	pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr16_+_30876115	0.726	NM_014712	SETD1A	SET domain containing 1A
chr15_-_38417564	0.717		C15orf52	chromosome 15 open reading frame 52
chr3_+_46894239	0.716	NM_000316	PTH1R	parathyroid hormone 1 receptor
chr7_+_130445394	0.712	NM_001145354	MKLN1	muskelin 1, intracellular mediator containing kelch motifs
chr17_-_59258762	0.709	NM_017647	FTSJ3	FtsJ homolog 3 (E. coli)
chr9_+_138760432	0.700		LOC100128593	hypothetical LOC100128593
chr10_-_73281056	0.700	NM_001042465 NM_001042466 NM_002778	PSAP	prosaposin
chr15_+_39638445	0.699	NM_006293	TYRO3	TYRO3 protein tyrosine kinase
chr6_-_30793436	0.697	NM_014641	MDC1	mediator of DNA-damage checkpoint 1
chr2_-_70901186	0.694	NM_173535	CLEC4F	C-type lectin domain family 4, member F
chr16_+_30326386	0.690		ZNF771	zinc finger protein 771
chr6_+_36518521	0.689	NM_173562	KCTD20	potassium channel tetramerisation domain containing 20
chr10_-_73281011	0.681		PSAP	prosaposin
chr22_-_25344037	0.678		CRYBB1	crystallin, beta B1
chr6_-_36518643	0.677	NM_152990	PXT1	peroxisomal, testis specific 1
chr7_-_150352484	0.671	NM_173681	ATG9B	ATG9 autophagy related 9 homolog B (S. cerevisiae)
chr1_-_6585485	0.666	NM_014851	KLHL21	kelch-like 21 (Drosophila)
chr2_+_161873239	0.665		PSMD14	proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
chr1_-_93030538	0.661	NM_005665	EVI5	ecotropic viral integration site 5
chr17_-_53764867	0.661
chr16_+_88511787	0.653	NM_002386	MC1R	melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
chr6_-_28999388	0.652		TRIM27	tripartite motif containing 27
chr3_+_142569988	0.649		ZBTB38	zinc finger and BTB domain containing 38
chr9_-_85512937	0.649	NM_013438 NM_053067	UBQLN1	ubiquilin 1
chr19_+_45564549	0.647		PLD3	phospholipase D family, member 3
chr9_-_115880372	0.640		AMBP	alpha-1-microglobulin/bikunin precursor
chr11_+_123600553	0.635	NM_001007249	OR8G2	olfactory receptor, family 8, subfamily G, member 2
chr16_+_85983499	0.629		MAP1LC3B	microtubule-associated protein 1 light chain 3 beta
chr9_-_129381086	0.626	NM_001035534	FAM129B	family with sequence similarity 129, member B
chr22_+_43451351	0.625	NM_001017530 NM_001198721 NM_015366	PRR5	proline rich 5 (renal)
chr17_-_70401299	0.619	NM_178128	FADS6	fatty acid desaturase domain family, member 6
chr6_+_150112549	0.619		PCMT1	protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr20_+_48240772	0.610	NM_005194	CEBPB	CCAAT/enhancer binding protein (C/EBP), beta
chr16_+_88515917	0.607	NM_001197181	TUBB3	tubulin, beta 3
chr11_-_62539857	0.606	NM_001184732 NM_001184733 NM_001184736 NM_004254	SLC22A8	solute carrier family 22 (organic anion transporter), member 8
chr6_-_33374275	0.606		RGL2	ral guanine nucleotide dissociation stimulator-like 2
chr7_+_44045202	0.594		FLJ35390	hypothetical LOC255031
chr6_+_56927665	0.593	NM_152731	BEND6	BEN domain containing 6
chr11_-_14498443	0.587		PSMA1	proteasome (prosome, macropain) subunit, alpha type, 1
chr7_-_100667750	0.587	NM_014343	CLDN15	claudin 15
chr1_+_153232685	0.586	NM_018655	LENEP	lens epithelial protein
chr4_-_84152985	0.581	NM_001115007	LIN54	lin-54 homolog (C. elegans)
chr20_+_34206070	0.576	NM_012156	EPB41L1	erythrocyte membrane protein band 4.1-like 1
chr5_+_10406980	0.575
chr15_+_86983038	0.575	NM_002201	ISG20	interferon stimulated exonuclease gene 20kDa
chr22_-_18687511	0.566	NM_033257	DGCR6L	DiGeorge syndrome critical region gene 6-like
chr7_-_75826251	0.566	NM_012479	YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
chr16_+_85983375	0.565		MAP1LC3B	microtubule-associated protein 1 light chain 3 beta
chr22_+_18090118	0.563		SEPT5-GP1BB	SEPT5-GP1BB read-through transcript
chr8_+_144888275	0.562		LOC100128338	hypothetical LOC100128338
chr22_-_39189369	0.559		MKL1	megakaryoblastic leukemia (translocation) 1
chr19_-_4510713	0.558		SEMA6B	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chrX_-_154216929	0.554	NM_001289	CLIC2	chloride intracellular channel 2
chr20_+_48240867	0.551		CEBPB	CCAAT/enhancer binding protein (C/EBP), beta
chr14_-_105589467	0.544		LOC100126583 IGHA1 IGHG1 IGHG2 IGHM	hypothetical LOC100126583 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 2 (G2m marker) immunoglobulin heavy constant mu
chr11_+_72660894	0.542	NM_004154	P2RY6	pyrimidinergic receptor P2Y, G-protein coupled, 6
chr2_+_27358800	0.540	NM_032546 NM_187841	TRIM54	tripartite motif containing 54
chr14_-_106193403	0.538		IGKV3-20	immunoglobulin kappa variable 3-20
chr11_-_14498462	0.536	NM_001143937 NM_002786	PSMA1	proteasome (prosome, macropain) subunit, alpha type, 1
chr11_+_62405736	0.535		SLC3A2	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr16_-_66075216	0.527	NM_001138	AGRP	agouti related protein homolog (mouse)
chr16_+_29984647	0.527		ALDOA	aldolase A, fructose-bisphosphate
chr6_+_32003380	0.523		C2	complement component 2
chr1_-_161105174	0.522	NM_178550	C1orf110	chromosome 1 open reading frame 110
chr7_-_96177010	0.522		SHFM1	split hand/foot malformation (ectrodactyly) type 1
chr1_+_46578976	0.512	NM_199044	NSUN4	NOP2/Sun domain family, member 4
chr11_+_60309396	0.510	NM_206893	MS4A10	membrane-spanning 4-domains, subfamily A, member 10
chr4_-_26100986	0.507	NM_000730	CCKAR	cholecystokinin A receptor
chr19_+_56337368	0.507	NM_014385 NM_016543	SIGLEC7	sialic acid binding Ig-like lectin 7
chr15_-_71830868	0.502	NM_001039614	C15orf59	chromosome 15 open reading frame 59
chr20_+_48240705	0.500		CEBPB	CCAAT/enhancer binding protein (C/EBP), beta
chr19_-_59438411	0.495	NM_024318	LILRB3 LILRA6	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
chr14_-_105785639	0.491
chrX_-_15421279	0.486	NM_001018109 NM_003662	PIR	pirin (iron-binding nuclear protein)
chr9_-_126309510	0.482	NM_004959	NR5A1	nuclear receptor subfamily 5, group A, member 1
chr11_+_74548472	0.481	NM_001145211	SLCO2B1	solute carrier organic anion transporter family, member 2B1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
5.38	7.97e-03	GO:0032313	regulation of Rab GTPase activity
5.38	7.97e-03	GO:0032483	regulation of Rab protein signal transduction
3.30	2.77e-02	GO:0032318	regulation of Ras GTPase activity
3.87	4.91e-02	GO:0051351	positive regulation of ligase activity

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
5.43	5.97e-05	GO:0000502	proteasome complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
6.11	1.50e-03	GO:0003823	antigen binding
5.27	2.33e-03	GO:0005097	Rab GTPase activator activity