Motif ID: NKX3-1.p2

Z-value: 1.754


Transcription factors associated with NKX3-1.p2:

Gene SymbolEntrez IDGene Name
NKX3-1 4824 NK3 homeobox 1



Activity profile for motif NKX3-1.p2.

activity profile for motif NKX3-1.p2


Sorted Z-values histogram for motif NKX3-1.p2

Sorted Z-values for motif NKX3-1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX3-1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr20_+_58146916 4.445 LOC284757
hypothetical protein LOC284757
chr11_-_62668268 3.710 NM_001136506
 SLC22A24
solute carrier family 22, member 24
chr2_+_165858586 3.056 NM_021007
 SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr17_-_53847937 2.996 RNF43
ring finger protein 43
chr14_-_74669864 2.942 TMED10
transmembrane emp24-like trafficking protein 10 (yeast)
chr6_+_26548678 2.890 NM_006994
NM_197974
 BTN3A3

butyrophilin, subfamily 3, member A3

chr6_-_52060327 2.876 NM_138694
NM_170724
 PKHD1

polycystic kidney and hepatic disease 1 (autosomal recessive)

chr4_+_119174947 2.756 NM_004784
 NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr6_+_53043729 2.688 NM_012347
 FBXO9
F-box protein 9
chr7_+_141457977 2.590 LOC93432
maltase-glucoamylase-like pseudogene
chr14_+_66901237 2.499 EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr12_+_79362256 2.478 NM_001145026
 PTPRQ
protein tyrosine phosphatase, receptor type, Q
chr10_+_116687904 2.463 NM_139169
 TRUB1
TruB pseudouridine (psi) synthase homolog 1 (E. coli)
chr8_+_23157094 2.427 NM_152272
 CHMP7
CHMP family, member 7
chr11_-_104332631 2.398 NM_033306
 CASP4
caspase 4, apoptosis-related cysteine peptidase
chr5_-_160044844 2.285 ATP10B
ATPase, class V, type 10B
chr12_-_18134319 2.280 NM_024730
 RERGL
RERG/RAS-like
chr20_+_29309127 2.231 NM_001037730
 DEFB115
defensin, beta 115
chr2_+_114390975 2.221 ACTR3
ARP3 actin-related protein 3 homolog (yeast)
chr2_+_69974581 2.124 NM_006857
 SNRNP27
small nuclear ribonucleoprotein 27kDa (U4/U6.U5)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
3.29 1.36e-15 GO:0007608 sensory perception of smell
3.16 9.05e-16 GO:0007606 sensory perception of chemical stimulus
2.33 1.35e-11 GO:0007600 sensory perception
1.78 7.01e-07 GO:0050877 neurological system process
1.68 1.10e-06 GO:0003008 system process
1.31 7.65e-06 GO:0032501 multicellular organismal process
1.25 1.13e-04 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.52 8.52e-06 GO:0005576 extracellular region
1.38 2.14e-07 GO:0005886 plasma membrane
1.37 2.59e-07 GO:0071944 cell periphery
1.21 1.04e-03 GO:0044425 membrane part
1.21 1.02e-02 GO:0016021 integral to membrane
1.20 1.23e-02 GO:0031224 intrinsic to membrane
1.17 3.26e-03 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
16.09 5.16e-06 GO:0005132 interferon-alpha/beta receptor binding
3.40 8.90e-17 GO:0004984 olfactory receptor activity
3.13 3.66e-02 GO:0004867 serine-type endopeptidase inhibitor activity
2.43 9.54e-15 GO:0004930 G-protein coupled receptor activity
1.94 1.26e-10 GO:0004888 transmembrane receptor activity
1.74 3.76e-09 GO:0004872 receptor activity
1.60 1.08e-07 GO:0004871 signal transducer activity
1.60 1.08e-07 GO:0060089 molecular transducer activity