Motif ID: NKX3-2.p2

Z-value: 2.104


Transcription factors associated with NKX3-2.p2:

Gene SymbolEntrez IDGene Name
NKX3-2 579 NK3 homeobox 2



Activity profile for motif NKX3-2.p2.

activity profile for motif NKX3-2.p2


Sorted Z-values histogram for motif NKX3-2.p2

Sorted Z-values for motif NKX3-2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX3-2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_238861830 1.633 NM_022817
 PER2
period homolog 2 (Drosophila)
chr8_+_32905027 1.546


chr2_+_17585462 1.463 VSNL1
visinin-like 1
chr2_+_228386800 1.401 NM_001130046
NM_004591
 CCL20

chemokine (C-C motif) ligand 20

chr16_-_71650034 1.376 NM_001164766
 ZFHX3
zinc finger homeobox 3
chr5_+_68746694 1.162 NM_001038603
 MARVELD2
MARVEL domain containing 2
chr3_+_48482213 1.151 NM_016381
NM_033629
 TREX1

three prime repair exonuclease 1

chr2_+_171280944 1.125 SP5
Sp5 transcription factor
chr16_+_55963883 1.111 CX3CL1
chemokine (C-X3-C motif) ligand 1
chr14_+_61653827 1.102 FLJ43390
hypothetical LOC646113
chr16_+_55963899 1.026 NM_002996
 CX3CL1
chemokine (C-X3-C motif) ligand 1
chr14_-_20642214 1.010


chr2_+_17585287 0.982 NM_003385
 VSNL1
visinin-like 1
chr2_-_136005238 0.972 NM_032143
 ZRANB3
zinc finger, RAN-binding domain containing 3
chr3_+_48482625 0.963 TREX1
three prime repair exonuclease 1
chr3_+_106568430 0.960 ALCAM
activated leukocyte cell adhesion molecule
chr3_+_106568334 0.938 NM_001627
 ALCAM
activated leukocyte cell adhesion molecule
chr14_-_22840249 0.896


chr14_+_30098079 0.894 NM_017769
 G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr3_+_106568243 0.886 ALCAM
activated leukocyte cell adhesion molecule

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
1.63 1.38e-02 GO:0060284 regulation of cell development
1.45 7.84e-03 GO:0032989 cellular component morphogenesis
1.44 4.72e-03 GO:0045595 regulation of cell differentiation
1.43 3.23e-02 GO:0000902 cell morphogenesis
1.38 2.88e-02 GO:2000026 regulation of multicellular organismal development
1.37 9.32e-03 GO:0022008 neurogenesis
1.36 1.01e-02 GO:0050793 regulation of developmental process
1.36 1.92e-02 GO:0048699 generation of neurons
1.31 1.02e-03 GO:0007399 nervous system development
1.27 2.29e-02 GO:0009653 anatomical structure morphogenesis
1.23 9.36e-03 GO:0048869 cellular developmental process
1.22 2.48e-02 GO:0030154 cell differentiation
1.20 1.03e-02 GO:0048518 positive regulation of biological process
1.20 3.15e-02 GO:0048519 negative regulation of biological process
1.10 4.51e-03 GO:0065007 biological regulation
1.10 1.44e-02 GO:0050789 regulation of biological process
1.06 1.31e-02 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.05 2.23e-02 GO:0044424 intracellular part
1.05 2.46e-02 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.45 5.78e-03 GO:0008092 cytoskeletal protein binding
1.13 2.17e-06 GO:0005515 protein binding
1.05 1.09e-02 GO:0005488 binding