Motif ID: NRF1.p2

Z-value: 4.424


Transcription factors associated with NRF1.p2:

Gene SymbolEntrez IDGene Name
NRF1 4899 nuclear respiratory factor 1



Activity profile for motif NRF1.p2.

activity profile for motif NRF1.p2


Sorted Z-values histogram for motif NRF1.p2

Sorted Z-values for motif NRF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NRF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_260408 10.177 NM_001013672
C17orf97
chromosome 17 open reading frame 97
chr1_-_3763480 4.896 KIAA0562
KIAA0562
chr1_+_3763704 4.140 NM_004402
DFFB
DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
chr6_+_33044353 3.937


chr21_+_33066281 3.744 C21orf49
chromosome 21 open reading frame 49
chr21_-_33065849 3.661 NM_013329
NM_016631
GCFC1

GC-rich sequence DNA-binding factor 1

chr20_+_48781457 3.396 NM_032521
PARD6B
par-6 partitioning defective 6 homolog beta (C. elegans)
chr19_-_7874426 3.007


chr14_+_22633728 3.002 C14orf119
chromosome 14 open reading frame 119
chr6_+_33044378 2.999 NM_005104
BRD2
bromodomain containing 2
chr1_-_3763620 2.987 NM_014704
KIAA0562
KIAA0562
chr12_-_52356375 2.977 NM_005176
ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr6_-_31728121 2.899 NM_001098534
BAG6
BCL2-associated athanogene 6
chr22_-_21814208 2.783 NM_014433
RTDR1
rhabdoid tumor deletion region gene 1
chr6_-_31728363 2.589 BAG6
BCL2-associated athanogene 6
chr7_+_99865340 2.579 MEPCE
methylphosphate capping enzyme
chr6_-_31728405 2.560 BAG6
BCL2-associated athanogene 6
chr19_-_40928131 2.544 NM_001040425
NM_144987
U2AF1L4

U2 small nuclear RNA auxiliary factor 1-like 4

chr6_-_41148061 2.538 NM_145063
C6orf130
chromosome 6 open reading frame 130
chr6_-_39305203 2.517 NM_003740
KCNK5
potassium channel, subfamily K, member 5
chr6_-_31728418 2.513 BAG6
BCL2-associated athanogene 6
chr19_+_40928300 2.484 NM_172341
PSENEN
presenilin enhancer 2 homolog (C. elegans)
chr20_+_36534871 2.449 NM_020336
RALGAPB
Ral GTPase activating protein, beta subunit (non-catalytic)
chr22_+_19078397 2.428 NM_003426
ZNF74
zinc finger protein 74
chr1_+_210275541 2.406 NM_016448
DTL
denticleless homolog (Drosophila)
chr12_-_52356123 2.367 ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chrX_-_73429101 2.361 MIR374AHG
mir-374a-545 cluster host gene (non-protein coding)
chr20_-_51644187 2.353 ZNF217
zinc finger protein 217
chr12_+_129922510 2.337 NM_006325
RAN
RAN, member RAS oncogene family
chr21_+_33619147 2.290 IFNAR1
interferon (alpha, beta and omega) receptor 1
chr1_-_210275402 2.261 NM_015434
INTS7
integrator complex subunit 7
chr9_+_132990760 2.244 NM_005085
NUP214
nucleoporin 214kDa
chr22_-_19686351 2.229 NM_001008695
NM_030573
THAP7

THAP domain containing 7

chr3_+_157875063 2.228 TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr11_+_63829616 2.164 NM_004451
ESRRA
estrogen-related receptor alpha
chr10_+_86078136 2.141 NM_018999
FAM190B
family with sequence similarity 190, member B
chr9_+_132990834 2.079 NUP214
nucleoporin 214kDa
chr14_-_22634134 2.066 ACIN1
apoptotic chromatin condensation inducer 1
chr3_-_197201497 2.048 SDHAP1
SDHAP2
succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 1
succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 2
chr1_-_201124848 2.004 NM_002871
RABIF
RAB interacting factor
chr19_+_1358664 1.998 DAZAP1
DAZ associated protein 1
chr19_+_7874701 1.995 MAP2K7
mitogen-activated protein kinase kinase 7
chr6_-_36623223 1.994 NM_007271
STK38
serine/threonine kinase 38
chr3_+_43707362 1.991 NM_016006
ABHD5
abhydrolase domain containing 5
chr3_+_49424757 1.965 TCTA
T-cell leukemia translocation altered gene
chr19_+_7874774 1.954 MAP2K7
mitogen-activated protein kinase kinase 7
chr6_-_163754903 1.939 LOC100526820
hypothetical LOC100526820
chr6_-_33787413 1.891 C6orf125
chromosome 6 open reading frame 125
chr19_+_7874765 1.891 MAP2K7
mitogen-activated protein kinase kinase 7
chr2_-_74588006 1.873 PCGF1
polycomb group ring finger 1
chr5_-_176365971 1.869 NM_016290
UIMC1
ubiquitin interaction motif containing 1
chr6_-_36623038 1.861 STK38
serine/threonine kinase 38
chr1_-_28842103 1.859 NM_001135218
NM_005644
TAF12

TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa

chr6_-_43651578 1.839 XPO5
exportin 5
chr22_-_21193037 1.814 ZNF280B
zinc finger protein 280B
chr3_-_47530083 1.811 NM_001031703
C3orf75
chromosome 3 open reading frame 75
chr3_-_47529810 1.804 C3orf75
chromosome 3 open reading frame 75
chr19_+_18655483 1.780 CRTC1
CREB regulated transcription coactivator 1
chr6_-_33787479 1.767 NM_032340
C6orf125
chromosome 6 open reading frame 125
chr7_-_156125876 1.759 C7orf13
chromosome 7 open reading frame 13
chr19_+_7874764 1.756 NM_145185
MAP2K7
mitogen-activated protein kinase kinase 7
chr21_+_46703192 1.747 NM_001146114
NM_001146115
NM_001146116
NM_015151
NM_206889
NM_206890
NM_206891
DIP2A






DIP2 disco-interacting protein 2 homolog A (Drosophila)






chr22_-_21193504 1.747 NM_080764
ZNF280B
zinc finger protein 280B
chr16_+_88102305 1.737 NM_003119
NM_199367
SPG7

spastic paraplegia 7 (pure and complicated autosomal recessive)

chr2_-_74588293 1.713 NM_032673
PCGF1
polycomb group ring finger 1
chr2_+_71148915 1.708 NM_017567
NAGK
N-acetylglucosamine kinase
chr10_-_74526662 1.685 NM_000917
NM_001017962
NM_001142595
NM_001142596
P4HA1



prolyl 4-hydroxylase, alpha polypeptide I



chr6_-_43651727 1.684 XPO5
exportin 5
chr6_-_153346283 1.674 NM_001142522
FBXO5
F-box protein 5
chr18_+_9465528 1.670 NM_006788
RALBP1
ralA binding protein 1
chr5_+_271428 1.665 SDHA
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr6_-_31882558 1.655 LSM2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr22_-_19685998 1.649 THAP7
THAP domain containing 7
chr7_-_149201696 1.645 LOC401431
hypothetical LOC401431
chr19_+_7874762 1.627 MAP2K7
mitogen-activated protein kinase kinase 7
chr7_+_44802834 1.617 PPIA
peptidylprolyl isomerase A (cyclophilin A)
chr20_+_25176698 1.588 NM_002862
PYGB
phosphorylase, glycogen; brain
chr14_+_92883289 1.584 NM_182971
COX8C
cytochrome c oxidase subunit 8C
chr6_-_43651745 1.575 NM_020750
XPO5
exportin 5
chr21_+_33619067 1.565 NM_000629
IFNAR1
interferon (alpha, beta and omega) receptor 1
chr21_-_46703020 1.560


chr19_+_18655391 1.558 NM_001098482
NM_015321
CRTC1

CREB regulated transcription coactivator 1

chr6_-_31728447 1.545 NM_004639
NM_080702
NM_080703
BAG6


BCL2-associated athanogene 6


chr6_-_99979850 1.540 NM_015491
NM_032870
SFRS18

splicing factor, arginine/serine-rich 18

chr2_-_37164919 1.537 HEATR5B
HEAT repeat containing 5B
chr1_-_247119516 1.535 NM_001136036
ZNF692
zinc finger protein 692
chr6_-_31882704 1.535 NM_021177
LSM2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr15_+_39739864 1.532 NM_001080541
NM_001164273
MGA

MAX gene associated

chr8_-_96350575 1.531 NM_177965
C8orf37
chromosome 8 open reading frame 37
chr7_+_99865189 1.522 NM_019606
MEPCE
methylphosphate capping enzyme
chr2_+_99124379 1.516 NM_144706
C2orf15
chromosome 2 open reading frame 15
chr2_-_99124466 1.514 NM_182911
TSGA10
testis specific, 10
chr5_+_271355 1.499 NM_004168
SDHA
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr7_-_27669029 1.487 NM_152740
HIBADH
3-hydroxyisobutyrate dehydrogenase
chr19_+_18655487 1.485 CRTC1
CREB regulated transcription coactivator 1
chr16_+_2419388 1.484 NM_001761
CCNF
cyclin F
chr15_+_39739933 1.475 MGA
MAX gene associated
chr10_-_74526596 1.475 P4HA1
prolyl 4-hydroxylase, alpha polypeptide I
chr16_+_28472780 1.467 CCDC101
coiled-coil domain containing 101
chr22_-_19543069 1.466 NM_058004
PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr19_+_7874820 1.463 MAP2K7
mitogen-activated protein kinase kinase 7
chr6_-_150011450 1.460 KATNA1
katanin p60 (ATPase containing) subunit A 1
chr1_-_229540101 1.458 NM_175876
EXOC8
exocyst complex component 8
chr19_+_63590446 1.452 NM_001009
RPS5
ribosomal protein S5
chr6_+_24775241 1.429 NM_001160094
NM_018473
ACOT13

acyl-CoA thioesterase 13

chr2_+_37165097 1.409 NM_174931
CCDC75
coiled-coil domain containing 75
chr1_+_210275735 1.407 DTL
denticleless homolog (Drosophila)
chr1_-_21868380 1.392 NM_001145657
NM_002885
RAP1GAP

RAP1 GTPase activating protein

chr5_+_134209628 1.386 C5orf24
chromosome 5 open reading frame 24
chr7_+_156126157 1.386 NM_030936
NM_001184996
RNF32

ring finger protein 32

chr6_+_43651855 1.376 NM_006502
POLH
polymerase (DNA directed), eta
chr2_-_37164962 1.362 NM_019024
HEATR5B
HEAT repeat containing 5B
chr6_-_33276416 1.354 RXRB
retinoid X receptor, beta
chr6_-_24774797 1.346 NM_016614
TDP2
tyrosyl-DNA phosphodiesterase 2
chr17_-_24302597 1.345 NM_001033561
NM_020889
PHF12

PHD finger protein 12

chr7_+_107171514 1.344 NM_024814
CBLL1
Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1
chr6_+_43651899 1.340 POLH
polymerase (DNA directed), eta
chr17_-_18526296 1.339 NM_001145045
ZNF286B
zinc finger protein 286B
chr19_+_45996881 1.333 NM_080732
EGLN2
egl nine homolog 2 (C. elegans)
chr19_-_18294933 1.310 NM_012321
LSM4
LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr10_-_73280964 1.302 PSAP
prosaposin
chr10_-_71663076 1.300 NM_021129
PPA1
pyrophosphatase (inorganic) 1
chr4_+_26471410 1.298 NM_001169117
NM_001169118
NM_020860
STIM2


stromal interaction molecule 2


chr6_-_33276347 1.297 NM_021976
RXRB
retinoid X receptor, beta
chr6_+_237033 1.297 NM_020185
DUSP22
dual specificity phosphatase 22
chr1_-_25446509 1.297 C1orf63
chromosome 1 open reading frame 63
chr2_+_71149193 1.296 NAGK
N-acetylglucosamine kinase
chr6_-_33276426 1.294 RXRB
retinoid X receptor, beta
chr14_+_22305570 1.292 NM_005015
OXA1L
oxidase (cytochrome c) assembly 1-like
chr5_+_134209444 1.287 NM_001135586
C5orf24
chromosome 5 open reading frame 24
chr16_+_27122796 1.284 NM_001145348
JMJD5
jumonji domain containing 5
chr5_+_271447 1.283 SDHA
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr20_+_25124333 1.282 NM_001114089
NM_001247
ENTPD6

ectonucleoside triphosphate diphosphohydrolase 6 (putative)

chr1_+_32251988 1.277 NM_006559
KHDRBS1
KH domain containing, RNA binding, signal transduction associated 1
chr2_+_71148936 1.273 NAGK
N-acetylglucosamine kinase
chr2_+_100545827 1.272 NM_024065
PDCL3
phosducin-like 3
chr6_-_150011551 1.263 KATNA1
katanin p60 (ATPase containing) subunit A 1
chr19_+_10932792 1.260 NM_001128849
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr1_-_1699723 1.259 NM_023018
NADK
NAD kinase
chr2_-_69518108 1.256 NFU1
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr22_+_19686434 1.255 FLJ39582
hypothetical LOC439931
chr8_-_22054939 1.254 NM_025232
REEP4
receptor accessory protein 4
chr6_+_44463418 1.251 CDC5L
CDC5 cell division cycle 5-like (S. pombe)
chr16_+_88280594 1.248 CDK10
cyclin-dependent kinase 10
chr5_+_271441 1.239 SDHA
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr16_+_88280569 1.230 NM_001098533
NM_001160367
NM_052987
NM_052988
CDK10



cyclin-dependent kinase 10



chr22_-_19543012 1.228 PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr3_+_49701965 1.227 RNF123
ring finger protein 123
chr1_-_40903897 1.226 NM_014747
RIMS3
regulating synaptic membrane exocytosis 3
chr6_-_24775106 1.224 TDP2
tyrosyl-DNA phosphodiesterase 2
chr19_-_47619992 1.221 LIPE
lipase, hormone-sensitive
chr20_-_35013589 1.216 SAMHD1
SAM domain and HD domain 1
chr10_-_73281047 1.215 PSAP
prosaposin
chr7_+_44802798 1.213 PPIA
peptidylprolyl isomerase A (cyclophilin A)
chr1_-_40903700 1.205 RIMS3
regulating synaptic membrane exocytosis 3
chr10_-_73281056 1.196 NM_001042465
NM_001042466
NM_002778
PSAP


prosaposin


chr1_-_229181203 1.190 TTC13
tetratricopeptide repeat domain 13
chr7_+_149651202 1.188 NM_001142928
NM_023942
LRRC61

leucine rich repeat containing 61

chr3_+_196870122 1.187 SDHAP2
succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 2
chr16_-_82736186 1.184 NM_001146051
NM_031463
HSDL1

hydroxysteroid dehydrogenase like 1

chr21_+_44377974 1.184 C21orf33
chromosome 21 open reading frame 33
chr3_+_49701978 1.182 NM_022064
RNF123
ring finger protein 123
chr22_-_19543099 1.177 PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr5_-_1852902 1.175 MRPL36
mitochondrial ribosomal protein L36
chr6_+_44463265 1.174 NM_001253
CDC5L
CDC5 cell division cycle 5-like (S. pombe)
chr1_+_231152942 1.166 NM_032324
NTPCR
nucleoside-triphosphatase, cancer-related
chr16_+_28472726 1.163 NM_138414
CCDC101
coiled-coil domain containing 101
chr12_+_123023521 1.160 NM_152437
ZNF664
zinc finger protein 664
chr2_-_69518051 1.160 NFU1
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr20_-_35013600 1.157 NM_015474
SAMHD1
SAM domain and HD domain 1
chr8_+_21833162 1.149 XPO7
exportin 7
chr3_-_198839026 1.149 LOC220729
succinate dehydrogenase complex, subunit A, flavoprotein pseudogene
chr1_+_210275752 1.147 DTL
denticleless homolog (Drosophila)
chr14_-_22127902 1.137 DAD1
defender against cell death 1
chr16_+_23754997 1.132 PRKCB
protein kinase C, beta
chr16_+_29734785 1.129 C16orf53
chromosome 16 open reading frame 53
chr5_-_271235 1.128 NM_145265
CCDC127
coiled-coil domain containing 127
chr7_+_138675644 1.126 LUC7L2
LUC7-like 2 (S. cerevisiae)
chr3_+_25806552 1.124 NM_001145391
NM_017897
OXSM

3-oxoacyl-ACP synthase, mitochondrial

chr16_-_4106186 1.117 NM_001116
ADCY9
adenylate cyclase 9
chr10_-_16899342 1.114 RSU1
Ras suppressor protein 1
chr2_+_197212522 1.110 NM_001080539
CCDC150
coiled-coil domain containing 150
chr7_-_149651594 1.107 NM_001164458
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr7_-_86526880 1.101 NM_001142749
KIAA1324L
KIAA1324-like
chr6_-_150011542 1.099 KATNA1
katanin p60 (ATPase containing) subunit A 1
chr1_-_218329773 1.096 NM_006085
BPNT1
3'(2'), 5'-bisphosphate nucleotidase 1
chr12_-_40824699 1.090 NM_001099650
NM_173601
GXYLT1

glucoside xylosyltransferase 1

chr7_+_149651481 1.085 LRRC61
leucine rich repeat containing 61
chr16_+_82736365 1.083 NM_178452
LRRC50
leucine rich repeat containing 50
chr10_-_73281011 1.082 PSAP
prosaposin
chr16_+_88566485 1.081 AFG3L1P
AFG3 ATPase family gene 3-like 1 (S. cerevisiae), pseudogene
chr1_-_115102109 1.077 CSDE1
cold shock domain containing E1, RNA-binding
chr16_-_88566370 1.071 NM_145039
CENPBD1
CENPB DNA-binding domains containing 1
chr7_-_139523187 1.066 NM_030647
JHDM1D
jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr17_+_55325268 1.061 RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr1_-_229181219 1.061 TTC13
tetratricopeptide repeat domain 13
chr22_+_19543248 1.057 NM_004782
SNAP29
synaptosomal-associated protein, 29kDa
chr1_-_115102106 1.047 CSDE1
cold shock domain containing E1, RNA-binding
chr16_+_29734990 1.047 NM_024516
C16orf53
chromosome 16 open reading frame 53
chr9_+_130491291 1.045 NM_003011
SET
SET nuclear oncogene

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.49 3.02e-34 GO:0044260 cellular macromolecule metabolic process
1.40 1.05e-26 GO:0043170 macromolecule metabolic process
1.33 4.43e-26 GO:0044237 cellular metabolic process
1.56 3.28e-23 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.64 3.62e-23 GO:0090304 nucleic acid metabolic process
1.28 3.51e-19 GO:0044238 primary metabolic process
1.46 9.35e-19 GO:0034641 cellular nitrogen compound metabolic process
1.25 1.30e-18 GO:0008152 metabolic process
1.45 1.88e-18 GO:0006807 nitrogen compound metabolic process
1.61 4.30e-17 GO:0010467 gene expression
1.60 6.92e-15 GO:0016070 RNA metabolic process
1.45 2.12e-13 GO:0044267 cellular protein metabolic process
1.53 4.85e-11 GO:0034645 cellular macromolecule biosynthetic process
1.52 7.29e-11 GO:0009059 macromolecule biosynthetic process
1.98 1.54e-10 GO:0016071 mRNA metabolic process
1.88 2.14e-10 GO:0006396 RNA processing
2.14 5.96e-10 GO:0006397 mRNA processing
1.88 3.02e-09 GO:0006259 DNA metabolic process
1.85 4.29e-09 GO:0051276 chromosome organization
2.22 1.10e-08 GO:0008380 RNA splicing
2.52 1.18e-08 GO:0000375 RNA splicing, via transesterification reactions
1.78 1.27e-08 GO:0022403 cell cycle phase
2.50 3.79e-08 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.50 3.79e-08 GO:0000398 nuclear mRNA splicing, via spliceosome
1.32 5.00e-08 GO:0019538 protein metabolic process
1.46 8.52e-08 GO:0006996 organelle organization
1.36 1.95e-07 GO:0044249 cellular biosynthetic process
1.85 2.47e-07 GO:0006974 response to DNA damage stimulus
1.10 4.82e-07 GO:0009987 cellular process
1.40 5.18e-07 GO:0043412 macromolecule modification
1.63 1.02e-06 GO:0033554 cellular response to stress
1.81 1.04e-06 GO:0044265 cellular macromolecule catabolic process
1.76 1.19e-06 GO:0000278 mitotic cell cycle
1.73 1.86e-06 GO:0009057 macromolecule catabolic process
1.32 2.98e-06 GO:0009058 biosynthetic process
1.39 3.35e-06 GO:0006464 protein modification process
1.53 7.95e-06 GO:0007049 cell cycle
1.60 8.65e-06 GO:0022402 cell cycle process
1.96 9.69e-06 GO:0006281 DNA repair
3.05 1.15e-05 GO:0051168 nuclear export
3.30 1.54e-05 GO:0006405 RNA export from nucleus
2.09 1.81e-05 GO:0016567 protein ubiquitination
2.04 2.34e-05 GO:0032446 protein modification by small protein conjugation
1.81 3.15e-05 GO:0000279 M phase
2.30 3.37e-05 GO:0051169 nuclear transport
2.28 6.47e-05 GO:0006913 nucleocytoplasmic transport
1.57 7.78e-05 GO:0046907 intracellular transport
2.51 1.09e-04 GO:0006403 RNA localization
1.89 1.13e-04 GO:0070647 protein modification by small protein conjugation or removal
2.61 1.22e-04 GO:0051028 mRNA transport
3.28 1.23e-04 GO:0006406 mRNA export from nucleus
2.53 1.35e-04 GO:0050657 nucleic acid transport
2.53 1.35e-04 GO:0050658 RNA transport
2.53 1.35e-04 GO:0051236 establishment of RNA localization
1.27 3.31e-04 GO:0071841 cellular component organization or biogenesis at cellular level
1.71 3.38e-04 GO:0006325 chromatin organization
1.48 3.42e-04 GO:0032774 RNA biosynthetic process
1.50 4.93e-04 GO:0045184 establishment of protein localization
1.43 5.53e-04 GO:0044248 cellular catabolic process
1.27 6.62e-04 GO:0071842 cellular component organization at cellular level
1.49 9.68e-04 GO:0006351 transcription, DNA-dependent
2.30 1.04e-03 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
1.49 1.31e-03 GO:0015031 protein transport
1.85 1.42e-03 GO:0000087 M phase of mitotic cell cycle
2.27 1.99e-03 GO:0006310 DNA recombination
1.85 2.33e-03 GO:0006366 transcription from RNA polymerase II promoter
2.94 2.35e-03 GO:0031124 mRNA 3'-end processing
1.38 3.08e-03 GO:0051641 cellular localization
1.78 3.19e-03 GO:0044257 cellular protein catabolic process
1.41 3.60e-03 GO:0051649 establishment of localization in cell
1.36 4.76e-03 GO:0033036 macromolecule localization
1.82 5.02e-03 GO:0000280 nuclear division
1.82 5.02e-03 GO:0007067 mitosis
1.76 6.57e-03 GO:0051603 proteolysis involved in cellular protein catabolic process
1.77 6.58e-03 GO:0043632 modification-dependent macromolecule catabolic process
1.79 7.38e-03 GO:0048285 organelle fission
2.09 9.57e-03 GO:0010498 proteasomal protein catabolic process
2.09 9.57e-03 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
2.62 9.68e-03 GO:0000956 nuclear-transcribed mRNA catabolic process
1.75 1.06e-02 GO:0019941 modification-dependent protein catabolic process
1.76 1.06e-02 GO:0006511 ubiquitin-dependent protein catabolic process
1.76 1.20e-02 GO:0051325 interphase
2.65 1.88e-02 GO:0006302 double-strand break repair
1.38 1.94e-02 GO:0008104 protein localization
1.68 1.97e-02 GO:0030163 protein catabolic process
2.58 2.00e-02 GO:0031123 RNA 3'-end processing
1.32 2.11e-02 GO:0009056 catabolic process
1.19 2.30e-02 GO:0071840 cellular component organization or biogenesis
1.74 2.76e-02 GO:0051329 interphase of mitotic cell cycle
1.66 3.34e-02 GO:0016568 chromatin modification
2.43 4.28e-02 GO:0006402 mRNA catabolic process
1.19 4.66e-02 GO:0016043 cellular component organization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.30 4.64e-45 GO:0043231 intracellular membrane-bounded organelle
1.30 4.95e-45 GO:0043227 membrane-bounded organelle
1.21 1.74e-41 GO:0044424 intracellular part
1.20 6.27e-41 GO:0005622 intracellular
1.25 1.74e-40 GO:0043229 intracellular organelle
1.25 3.15e-40 GO:0043226 organelle
1.42 2.37e-37 GO:0005634 nucleus
1.67 1.11e-26 GO:0044428 nuclear part
1.35 1.16e-25 GO:0044446 intracellular organelle part
1.33 2.84e-24 GO:0044422 organelle part
1.60 2.84e-22 GO:0070013 intracellular organelle lumen
1.67 3.65e-22 GO:0031981 nuclear lumen
1.58 8.62e-22 GO:0031974 membrane-enclosed lumen
1.57 4.85e-21 GO:0043233 organelle lumen
1.78 2.47e-20 GO:0005654 nucleoplasm
1.18 1.70e-13 GO:0005737 cytoplasm
1.34 1.45e-12 GO:0032991 macromolecular complex
1.91 1.53e-10 GO:0005694 chromosome
1.20 1.86e-09 GO:0044444 cytoplasmic part
1.89 2.67e-08 GO:0044427 chromosomal part
1.70 2.75e-08 GO:0044451 nucleoplasm part
1.81 1.29e-07 GO:0030529 ribonucleoprotein complex
1.26 1.39e-05 GO:0043234 protein complex
1.04 2.26e-05 GO:0044464 cell part
1.04 2.36e-05 GO:0005623 cell
1.31 3.81e-05 GO:0005829 cytosol
2.01 5.96e-05 GO:0000785 chromatin
1.25 2.43e-04 GO:0043228 non-membrane-bounded organelle
1.25 2.43e-04 GO:0043232 intracellular non-membrane-bounded organelle
2.31 5.94e-04 GO:0016607 nuclear speck
2.05 6.34e-04 GO:0005819 spindle
1.72 1.63e-03 GO:0005815 microtubule organizing center
2.18 1.88e-03 GO:0005681 spliceosomal complex
2.55 2.91e-03 GO:0071013 catalytic step 2 spliceosome
1.99 3.89e-03 GO:0044454 nuclear chromosome part
2.09 5.57e-03 GO:0000151 ubiquitin ligase complex
1.82 7.87e-03 GO:0005813 centrosome
1.84 8.69e-03 GO:0000228 nuclear chromosome
2.45 9.64e-03 GO:0031461 cullin-RING ubiquitin ligase complex
1.45 1.10e-02 GO:0015630 microtubule cytoskeleton
2.24 1.73e-02 GO:0032993 protein-DNA complex
2.53 1.88e-02 GO:0000922 spindle pole
1.76 3.07e-02 GO:0016604 nuclear body
1.29 3.95e-02 GO:0005739 mitochondrion

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.41 6.91e-17 GO:0003676 nucleic acid binding
1.22 7.31e-16 GO:0005515 protein binding
1.74 8.58e-11 GO:0003723 RNA binding
1.90 3.06e-08 GO:0016874 ligase activity
1.34 2.34e-07 GO:0003677 DNA binding
1.34 6.81e-07 GO:0000166 nucleotide binding
1.08 1.98e-06 GO:0005488 binding
1.97 8.78e-06 GO:0016879 ligase activity, forming carbon-nitrogen bonds
2.00 1.83e-05 GO:0016881 acid-amino acid ligase activity
1.17 3.16e-05 GO:0003824 catalytic activity
2.00 1.36e-04 GO:0019787 small conjugating protein ligase activity
2.01 2.47e-04 GO:0004842 ubiquitin-protein ligase activity
1.25 2.66e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.59 3.36e-02 GO:0003712 transcription cofactor activity
1.24 3.57e-02 GO:0032553 ribonucleotide binding
1.24 3.57e-02 GO:0032555 purine ribonucleotide binding
1.58 3.68e-02 GO:0000988 protein binding transcription factor activity
1.58 3.68e-02 GO:0000989 transcription factor binding transcription factor activity
2.43 3.68e-02 GO:0042393 histone binding
2.43 3.68e-02 GO:0047485 protein N-terminus binding
1.24 3.98e-02 GO:0017076 purine nucleotide binding