Motif ID: PATZ1.p2

Z-value: 2.873


Transcription factors associated with PATZ1.p2:

Gene SymbolEntrez IDGene Name
PATZ1 23598 POZ (BTB) and AT hook containing zinc finger 1



Activity profile for motif PATZ1.p2.

activity profile for motif PATZ1.p2


Sorted Z-values histogram for motif PATZ1.p2

Sorted Z-values for motif PATZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PATZ1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr20_-_51644187 3.957 ZNF217
zinc finger protein 217
chr17_+_34114924 3.125 MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr22_-_21231421 2.760 NM_206955
NM_206956
NM_006115
NM_206953
NM_206954
 PRAME




preferentially expressed antigen in melanoma




chr9_+_132961723 2.686 AIF1L
allograft inflammatory factor 1-like
chr6_+_7052798 2.642 NM_001168344
 RREB1
ras responsive element binding protein 1
chr19_-_1966628 2.630 NM_017797
 BTBD2
BTB (POZ) domain containing 2
chr11_+_63829616 2.442 NM_004451
 ESRRA
estrogen-related receptor alpha
chr6_+_7052985 2.386 NM_001003698
NM_001003699
NM_001003700
 RREB1


ras responsive element binding protein 1


chr20_+_1154763 2.232 NM_001136566
 RAD21L1
RAD21-like 1 (S. pombe)
chr5_-_176671897 2.213 NM_001142935
NM_031300
 MXD3

MAX dimerization protein 3

chr1_-_40903897 2.208 NM_014747
 RIMS3
regulating synaptic membrane exocytosis 3
chr7_-_150305933 2.200 NM_000238
NM_172056
 KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

chr1_-_40903700 2.198 RIMS3
regulating synaptic membrane exocytosis 3
chr9_+_70509925 2.138 NM_003558
 PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr22_+_18081968 2.104 NM_002688
 SEPT5
septin 5
chr17_-_34015631 2.101 NM_025248
 SRCIN1
SRC kinase signaling inhibitor 1
chr9_+_132961683 2.065 NM_001185095
NM_001185096
NM_031426
 AIF1L


allograft inflammatory factor 1-like


chr20_-_39680405 2.031 NM_032221
 CHD6
chromodomain helicase DNA binding protein 6
chr2_+_231968578 1.971 NM_145236
 B3GNT7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr1_-_32574185 1.965 NM_023009
 MARCKSL1
MARCKS-like 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 138 entries
enrichment   p-value GO term description
1.57 1.76e-06 GO:0016569 covalent chromatin modification
1.57 2.65e-06 GO:0016570 histone modification
1.52 1.44e-06 GO:0048011 nerve growth factor receptor signaling pathway
1.50 5.49e-11 GO:0016568 chromatin modification
1.43 4.21e-02 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
1.39 1.06e-02 GO:0051129 negative regulation of cellular component organization
1.37 6.06e-03 GO:0045596 negative regulation of cell differentiation
1.37 2.65e-02 GO:0007507 heart development
1.35 1.58e-04 GO:0007264 small GTPase mediated signal transduction
1.33 3.43e-05 GO:0006325 chromatin organization
1.33 8.12e-05 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.32 9.10e-03 GO:0070647 protein modification by small protein conjugation or removal
1.31 5.38e-06 GO:0045893 positive regulation of transcription, DNA-dependent
1.31 2.33e-04 GO:0000904 cell morphogenesis involved in differentiation
1.31 1.50e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
1.31 2.86e-02 GO:0007411 axon guidance
1.31 4.02e-02 GO:0051098 regulation of binding
1.31 4.14e-02 GO:0051093 negative regulation of developmental process
1.30 5.30e-10 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.30 2.01e-06 GO:0010628 positive regulation of gene expression

Gene overrepresentation in compartment category:

Showing 1 to 20 of 42 entries
enrichment   p-value GO term description
1.65 2.42e-04 GO:0016585 chromatin remodeling complex
1.50 2.57e-02 GO:0005925 focal adhesion
1.47 4.12e-02 GO:0030055 cell-substrate junction
1.42 2.77e-02 GO:0000151 ubiquitin ligase complex
1.40 7.83e-04 GO:0016604 nuclear body
1.40 5.57e-03 GO:0031252 cell leading edge
1.39 1.64e-03 GO:0000228 nuclear chromosome
1.39 1.64e-02 GO:0044454 nuclear chromosome part
1.30 2.44e-03 GO:0048471 perinuclear region of cytoplasm
1.27 1.38e-06 GO:0044451 nucleoplasm part
1.26 6.80e-17 GO:0031981 nuclear lumen
1.26 7.48e-12 GO:0005654 nucleoplasm
1.26 1.91e-04 GO:0044431 Golgi apparatus part
1.25 3.74e-20 GO:0044428 nuclear part
1.25 6.23e-03 GO:0000139 Golgi membrane
1.23 2.70e-06 GO:0005794 Golgi apparatus
1.21 1.40e-14 GO:0070013 intracellular organelle lumen
1.21 2.87e-14 GO:0043233 organelle lumen
1.20 3.72e-13 GO:0031974 membrane-enclosed lumen
1.20 3.68e-12 GO:0005829 cytosol

Gene overrepresentation in function category:

Showing 1 to 20 of 48 entries
enrichment   p-value GO term description
1.67 3.47e-03 GO:0042393 histone binding
1.45 6.01e-04 GO:0003682 chromatin binding
1.43 1.42e-06 GO:0008134 transcription factor binding
1.41 2.83e-09 GO:0019904 protein domain specific binding
1.41 7.97e-04 GO:0003713 transcription coactivator activity
1.40 7.44e-04 GO:0019787 small conjugating protein ligase activity
1.40 2.43e-02 GO:0000287 magnesium ion binding
1.39 2.23e-03 GO:0004842 ubiquitin-protein ligase activity
1.36 2.04e-03 GO:0016881 acid-amino acid ligase activity
1.36 2.45e-02 GO:0000975 regulatory region DNA binding
1.36 2.45e-02 GO:0001067 regulatory region nucleic acid binding
1.36 2.45e-02 GO:0044212 transcription regulatory region DNA binding
1.35 3.55e-04 GO:0016563 transcription activator activity
1.34 9.34e-06 GO:0004674 protein serine/threonine kinase activity
1.34 1.96e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.32 1.32e-08 GO:0043565 sequence-specific DNA binding
1.32 3.12e-04 GO:0003712 transcription cofactor activity
1.32 4.06e-04 GO:0000988 protein binding transcription factor activity
1.32 4.06e-04 GO:0000989 transcription factor binding transcription factor activity
1.32 3.27e-03 GO:0003779 actin binding