Motif ID: PAX2.p2

Z-value: 1.550


Transcription factors associated with PAX2.p2:

Gene SymbolEntrez IDGene Name
PAX2 5076 paired box 2



Activity profile for motif PAX2.p2.

activity profile for motif PAX2.p2


Sorted Z-values histogram for motif PAX2.p2

Sorted Z-values for motif PAX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_141136691 1.202 NM_022131
 CLSTN2
calsyntenin 2
chr15_+_41597097 0.997 NM_002373
 MAP1A
microtubule-associated protein 1A
chr16_+_2503994 0.993 ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr16_+_29726962 0.951 MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr11_+_66915997 0.907 NM_004584
 RAD9A
RAD9 homolog A (S. pombe)
chr20_+_43953428 0.894 CTSA
cathepsin A
chr12_+_28234657 0.881


chr17_-_39556535 0.872 NM_001015053
NM_005474
 HDAC5

histone deacetylase 5

chr10_+_69314347 0.864 NM_012238
 SIRT1
sirtuin 1
chr17_-_39556483 0.859 HDAC5
histone deacetylase 5
chr16_-_5023914 0.803 NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr16_-_5023934 0.802 NM_016256
 NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr10_-_3817418 0.801 NM_001160124
NM_001160125
NM_001300
 KLF6


Kruppel-like factor 6


chr1_+_221168388 0.786 NM_032890
 DISP1
dispatched homolog 1 (Drosophila)
chr1_+_159550789 0.767 NM_001035511
NM_001035512
NM_001035513
NM_003001
 SDHC



succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa



chrX_-_102205736 0.750 BEX1
brain expressed, X-linked 1
chr6_-_33493898 0.732 CUTA
cutA divalent cation tolerance homolog (E. coli)
chr17_-_38081967 0.715 NM_024927
 PLEKHH3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr1_-_153477511 0.692 GBA
glucosidase, beta, acid
chr12_-_113330574 0.682 NM_000192
NM_080717
 TBX5

T-box 5


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
1.67 1.93e-02 GO:0032870 cellular response to hormone stimulus
1.47 8.34e-04 GO:0046907 intracellular transport
1.34 1.55e-02 GO:0051649 establishment of localization in cell
1.31 2.04e-02 GO:0033036 macromolecule localization
1.28 2.01e-03 GO:0010467 gene expression
1.28 6.49e-03 GO:0016070 RNA metabolic process
1.27 4.40e-04 GO:0090304 nucleic acid metabolic process
1.26 2.25e-05 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.23 6.68e-05 GO:0006807 nitrogen compound metabolic process
1.23 8.49e-05 GO:0034641 cellular nitrogen compound metabolic process
1.18 3.48e-04 GO:0044260 cellular macromolecule metabolic process
1.16 6.10e-04 GO:0043170 macromolecule metabolic process
1.13 7.92e-04 GO:0044237 cellular metabolic process
1.11 6.29e-03 GO:0008152 metabolic process
1.10 5.64e-08 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 21 entries
enrichment   p-value GO term description
1.26 2.80e-02 GO:0005739 mitochondrion
1.23 3.77e-03 GO:0005829 cytosol
1.22 4.41e-03 GO:0044428 nuclear part
1.22 3.21e-02 GO:0031981 nuclear lumen
1.21 6.10e-03 GO:0031974 membrane-enclosed lumen
1.21 8.61e-03 GO:0043233 organelle lumen
1.21 8.89e-03 GO:0070013 intracellular organelle lumen
1.21 1.37e-02 GO:0031090 organelle membrane
1.18 2.93e-08 GO:0044422 organelle part
1.18 1.35e-07 GO:0044446 intracellular organelle part
1.18 1.60e-03 GO:0032991 macromolecular complex
1.18 6.59e-03 GO:0043234 protein complex
1.17 1.25e-07 GO:0044444 cytoplasmic part
1.14 1.57e-10 GO:0043231 intracellular membrane-bounded organelle
1.14 1.76e-10 GO:0043227 membrane-bounded organelle
1.14 8.26e-10 GO:0005737 cytoplasm
1.14 2.40e-04 GO:0005634 nucleus
1.13 5.24e-11 GO:0043229 intracellular organelle
1.12 5.93e-11 GO:0043226 organelle
1.11 1.27e-13 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
1.52 4.19e-02 GO:0000988 protein binding transcription factor activity
1.52 4.19e-02 GO:0000989 transcription factor binding transcription factor activity
1.38 2.37e-02 GO:0019899 enzyme binding
1.22 5.66e-19 GO:0005515 protein binding
1.09 5.35e-09 GO:0005488 binding