Motif ID: PAX5.p2

Z-value: 1.537


Transcription factors associated with PAX5.p2:

Gene SymbolEntrez IDGene Name
PAX5 5079 paired box 5



Activity profile for motif PAX5.p2.

activity profile for motif PAX5.p2


Sorted Z-values histogram for motif PAX5.p2

Sorted Z-values for motif PAX5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX5.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_133923758 6.937 NCRNA00119
non-protein coding RNA 119
chr3_-_133923992 5.837 NPHP3-ACAD11
NPHP3-ACAD11 read-through transcript
chr3_-_133923906 5.802 NM_153240
 NPHP3
nephronophthisis 3 (adolescent)
chrX_+_43399101 4.344 MAOA
monoamine oxidase A
chr21_-_43671355 3.621 NM_173354
 SIK1
salt-inducible kinase 1
chr12_-_93568336 3.236 NM_020698
 TMCC3
transmembrane and coiled-coil domain family 3
chr19_+_61742111 2.983 NM_020828
 ZFP28
zinc finger protein 28 homolog (mouse)
chr4_+_7245218 2.514 NM_020777
 SORCS2
sortilin-related VPS10 domain containing receptor 2
chr9_+_139566129 2.468 NM_032477
 MRPL41
mitochondrial ribosomal protein L41
chr17_-_59131194 2.440 LIMD2
LIM domain containing 2
chrX_+_118486390 2.357 NM_001152
 SLC25A5
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr14_+_102128741 2.322 RCOR1
REST corepressor 1
chr14_+_99329198 2.280 NM_001008707
NM_004434
 EML1

echinoderm microtubule associated protein like 1

chr14_+_102128844 2.276 NM_015156
 RCOR1
REST corepressor 1
chr17_+_40565492 2.105 NM_001135704
 ACBD4
acyl-CoA binding domain containing 4
chrX_+_118486419 2.086 SLC25A5
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr4_-_186629841 2.027 NM_001145411
NM_152775
 CCDC110

coiled-coil domain containing 110

chr16_+_65790514 2.004 NM_024712
 ELMO3
engulfment and cell motility 3
chr10_+_129595349 1.982 PTPRE
protein tyrosine phosphatase, receptor type, E
chr1_-_233879617 1.943 NM_001098722
 GNG4
guanine nucleotide binding protein (G protein), gamma 4

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 111 entries
enrichment   p-value GO term description
2.75 3.47e-02 GO:0002040 sprouting angiogenesis
2.18 2.22e-02 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway
1.91 4.47e-02 GO:0042058 regulation of epidermal growth factor receptor signaling pathway
1.87 8.92e-04 GO:0060828 regulation of canonical Wnt receptor signaling pathway
1.85 9.49e-03 GO:0007173 epidermal growth factor receptor signaling pathway
1.77 1.61e-03 GO:0010720 positive regulation of cell development
1.72 6.42e-04 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.71 9.73e-04 GO:0022604 regulation of cell morphogenesis
1.69 1.27e-03 GO:0030111 regulation of Wnt receptor signaling pathway
1.61 2.34e-05 GO:0048011 nerve growth factor receptor signaling pathway
1.58 1.73e-07 GO:0060284 regulation of cell development
1.56 2.98e-09 GO:0009968 negative regulation of signal transduction
1.55 5.81e-03 GO:0035239 tube morphogenesis
1.52 7.84e-03 GO:0045664 regulation of neuron differentiation
1.50 5.53e-03 GO:0002009 morphogenesis of an epithelium
1.49 3.42e-03 GO:0050767 regulation of neurogenesis
1.47 8.25e-07 GO:0010648 negative regulation of cell communication
1.47 1.23e-06 GO:0023057 negative regulation of signaling
1.47 2.22e-03 GO:0035295 tube development
1.46 6.64e-08 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway

Gene overrepresentation in compartment category:

Showing 1 to 20 of 25 entries
enrichment   p-value GO term description
1.62 2.97e-02 GO:0005925 focal adhesion
1.60 7.30e-04 GO:0005912 adherens junction
1.50 9.98e-03 GO:0070161 anchoring junction
1.38 4.02e-02 GO:0005635 nuclear envelope
1.32 2.23e-03 GO:0000139 Golgi membrane
1.27 1.13e-05 GO:0005794 Golgi apparatus
1.27 6.10e-03 GO:0044431 Golgi apparatus part
1.25 8.52e-03 GO:0015630 microtubule cytoskeleton
1.22 2.81e-09 GO:0005829 cytosol
1.20 3.95e-05 GO:0012505 endomembrane system
1.15 1.34e-03 GO:0031090 organelle membrane
1.15 1.75e-03 GO:0044428 nuclear part
1.14 7.99e-15 GO:0044444 cytoplasmic part
1.13 1.30e-22 GO:0005737 cytoplasm
1.12 4.87e-10 GO:0005634 nucleus
1.11 4.54e-17 GO:0043227 membrane-bounded organelle
1.11 6.38e-17 GO:0043231 intracellular membrane-bounded organelle
1.09 1.67e-24 GO:0005622 intracellular
1.09 1.12e-22 GO:0044424 intracellular part
1.09 8.96e-15 GO:0043226 organelle

Gene overrepresentation in function category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
1.65 6.80e-03 GO:0017124 SH3 domain binding
1.54 6.97e-03 GO:0005085 guanyl-nucleotide exchange factor activity
1.43 2.76e-06 GO:0019904 protein domain specific binding
1.39 2.84e-05 GO:0030695 GTPase regulator activity
1.38 3.80e-05 GO:0060589 nucleoside-triphosphatase regulator activity
1.27 2.97e-05 GO:0030234 enzyme regulator activity
1.26 2.74e-03 GO:0042802 identical protein binding
1.23 3.71e-02 GO:0019899 enzyme binding
1.14 1.80e-20 GO:0005515 protein binding
1.07 3.65e-15 GO:0005488 binding