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• Activity deltas table
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Motif ID: PAX6.p2

Z-value: 0.511

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr5_-_94250357	0.693		MCTP1	multiple C2 domains, transmembrane 1
chr4_-_174557191	0.677	NM_007281	SCRG1	stimulator of chondrogenesis 1
chr15_+_49760841	0.580	NM_001165257 NM_013243	SCG3	secretogranin III
chr6_-_42270671	0.508	NM_002098	GUCA1B	guanylate cyclase activator 1B (retina)
chr2_+_214984705	0.432	NM_001080500	VWC2L	von Willebrand factor C domain containing protein 2-like
chr16_+_70646008	0.404	NM_001126102 NM_005143	HP	haptoglobin
chr6_-_131333173	0.378		EPB41L2	erythrocyte membrane protein band 4.1-like 2
chr19_+_15920817	0.335	NM_001004465	OR10H4	olfactory receptor, family 10, subfamily H, member 4
chr5_-_141318810	0.314	NM_016580	PCDH12	protocadherin 12
chr12_-_68379331	0.294	NM_032735	BEST3	bestrophin 3
chr6_+_147568795	0.260		STXBP5	syntaxin binding protein 5 (tomosyn)
chr11_+_55776251	0.255	NM_001004747	OR5T3	olfactory receptor, family 5, subfamily T, member 3
chr1_+_246703249	0.239	NM_001005495	OR2T3	olfactory receptor, family 2, subfamily T, member 3
chr2_+_39000007	0.236	NM_001145451	ARHGEF33	Rho guanine nucleotide exchange factor (GEF) 33
chr16_+_52037186	0.229		RBL2	retinoblastoma-like 2 (p130)
chr4_+_70896236	0.227	NM_001009181 NM_003154	STATH	statherin
chr5_-_22248630	0.214		CDH12	cadherin 12, type 2 (N-cadherin 2)
chr3_-_120861959	0.203	NM_022135	POPDC2	popeye domain containing 2
chr8_+_18123456	0.198	NM_001160174	NAT1	N-acetyltransferase 1 (arylamine N-acetyltransferase)
chr9_+_102380156	0.197	NM_001018116	MURC	muscle-related coiled-coil protein
chr12_+_55201854	0.195	NM_002898	RBMS2	RNA binding motif, single stranded interacting protein 2
chr1_+_97033103	0.193
chr12_-_69317441	0.191	NM_001109754	PTPRB	protein tyrosine phosphatase, receptor type, B
chr19_-_56825400	0.184	NM_003830	SIGLEC5	sialic acid binding Ig-like lectin 5
chr19_+_59941785	0.184	NM_015868	KIR2DS2 KIR2DL3	killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
chr11_-_123130435	0.182	NM_001005188	OR6X1	olfactory receptor, family 6, subfamily X, member 1
chr17_-_1195096	0.174		PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr6_+_25760352	0.168	NM_006998	SCGN	secretagogin, EF-hand calcium binding protein
chr2_+_170074457	0.164	NM_006063	KBTBD10	kelch repeat and BTB (POZ) domain containing 10
chr16_+_70654625	0.164	NM_020995	HPR	haptoglobin-related protein
chr20_-_43577677	0.158	NM_006652	SPINT3	serine peptidase inhibitor, Kunitz type, 3
chr4_-_64957595	0.155	NM_001010874	TECRL	trans-2,3-enoyl-CoA reductase-like
chr10_-_82039158	0.147	NM_000429	MAT1A	methionine adenosyltransferase I, alpha
chr8_+_39911630	0.144	NM_194294	IDO2	indoleamine 2,3-dioxygenase 2
chr1_-_12830728	0.143	NM_001146181	HNRNPCL1 LOC649330	heterogeneous nuclear ribonucleoprotein C-like 1 heterogeneous nuclear ribonucleoprotein C-like
chr14_-_30927931	0.140	NM_015473	HEATR5A	HEAT repeat containing 5A
chrX_-_148604506	0.138	NM_001011544	MAGEA11	melanoma antigen family A, 11
chr5_+_79651545	0.131	NM_032567	SPZ1	spermatogenic leucine zipper 1
chr20_-_32877029	0.119	NM_014071	NCOA6	nuclear receptor coactivator 6
chr3_-_147805715	0.119		PLSCR5	phospholipid scramblase family, member 5
chr3_-_58627509	0.116	NM_138805	FAM3D	family with sequence similarity 3, member D
chr10_+_118340460	0.115	NM_006229	PNLIPRP1	pancreatic lipase-related protein 1
chr3_+_153499883	0.113	NM_207293 NM_207294 NM_207295 NM_207296 NM_207297	MBNL1	muscleblind-like (Drosophila)
chr12_-_10433852	0.108	NM_007360	KLRK1	killer cell lectin-like receptor subfamily K, member 1
chr1_+_87153025	0.108		HS2ST1	heparan sulfate 2-O-sulfotransferase 1
chr19_+_56990222	0.100	NM_002030	FPR3	formyl peptide receptor 3
chr8_-_62764839	0.098	NM_001164750 NM_001164751 NM_001164752 NM_001164753 NM_020164 NM_032467 NM_032468	ASPH	aspartate beta-hydroxylase
chr12_+_67366989	0.097	NM_020401	NUP107	nucleoporin 107kDa
chr1_+_108794426	0.096	NM_001143987 NM_001143988	NBPF4 NBPF6	neuroblastoma breakpoint family, member 4 neuroblastoma breakpoint family, member 6
chr5_-_58918031	0.096	NM_006203	PDE4D	phosphodiesterase 4D, cAMP-specific
chr15_-_23204887	0.093	NM_000462	UBE3A	ubiquitin protein ligase E3A
chr16_-_18845223	0.091	NM_015092	SMG1	SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
chr17_-_36294962	0.090	NM_019010	KRT20	keratin 20
chr4_+_77575276	0.088	NM_020859	SHROOM3	shroom family member 3
chr7_+_90176647	0.086	NM_012395	CDK14	cyclin-dependent kinase 14
chr1_-_87152396	0.082		SEP15	15 kDa selenoprotein
chr3_-_148605996	0.082	NM_001168379	ZIC4	Zic family member 4
chr19_-_14800275	0.081	NM_017506	OR7A5	olfactory receptor, family 7, subfamily A, member 5
chr3_-_150533948	0.081	NM_001184723 NM_138786	TM4SF18	transmembrane 4 L six family member 18
chr4_-_10295412	0.078	NM_052964	CLNK	cytokine-dependent hematopoietic cell linker
chr2_-_171631728	0.078	NM_001136555	TLK1	tousled-like kinase 1
chr18_+_59571256	0.078	NM_001040147	SERPINB7	serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr1_+_93830106	0.078		LOC100129046	hypothetical LOC100129046
chr2_-_133256097	0.076		NCKAP5	NCK-associated protein 5
chr5_+_57823017	0.074	NM_152687	GAPT	GRB2-binding adaptor protein, transmembrane
chr12_-_18134319	0.073	NM_024730	RERGL	RERG/RAS-like
chr7_-_26198673	0.072		HNRNPA2B1	heterogeneous nuclear ribonucleoprotein A2/B1
chr17_-_33602374	0.072	NM_032258	TBC1D3C TBC1D3G TBC1D3 TBC1D3F	TBC1 domain family, member 3C TBC1 domain family, member 3G TBC1 domain family, member 3 TBC1 domain family, member 3F
chr20_+_31106797	0.072	NM_182658	C20orf185	chromosome 20 open reading frame 185
chr20_+_31713750	0.071	NM_080825	C20orf144	chromosome 20 open reading frame 144
chr7_-_72761367	0.071		STX1A	syntaxin 1A (brain)
chrX_+_50670474	0.070	NM_005448	BMP15	bone morphogenetic protein 15
chr20_-_45360903	0.069		ZMYND8	zinc finger, MYND-type containing 8
chr9_-_115901157	0.068	NM_138424	KIF12	kinesin family member 12
chr6_-_50097606	0.067	NM_001037497 NM_001037728	DEFB110	defensin, beta 110 locus
chr3_+_122769467	0.065	NM_001012659	ARGFX	arginine-fifty homeobox
chrX_-_52700674	0.064	NM_173358	SSX7	synovial sarcoma, X breakpoint 7
chr1_+_145841569	0.062	NM_005267	GJA8	gap junction protein, alpha 8, 50kDa
chr17_-_31616071	0.061	NM_001001418 NM_032258	TBC1D3B TBC1D3C TBC1D3G TBC1D3F	TBC1 domain family, member 3B TBC1 domain family, member 3C TBC1 domain family, member 3G TBC1 domain family, member 3F
chr2_-_138762909	0.061
chr1_+_35623688	0.061		ZMYM4	zinc finger, MYM-type 4
chr11_+_117680504	0.061	NM_000733	CD3E	CD3e molecule, epsilon (CD3-TCR complex)
chr1_-_54861656	0.060	NM_176782	FAM151A	family with sequence similarity 151, member A
chr4_-_26100986	0.059	NM_000730	CCKAR	cholecystokinin A receptor
chr10_-_79298876	0.058		DLG5	discs, large homolog 5 (Drosophila)
chr10_+_102212787	0.056	NM_003393	WNT8B	wingless-type MMTV integration site family, member 8B
chr4_+_71298187	0.056	NM_021225	PROL1	proline rich, lacrimal 1
chr20_+_18070867	0.055	NM_020536	CSRP2BP	CSRP2 binding protein
chr14_+_28311740	0.055		C14orf23	chromosome 14 open reading frame 23
chr16_-_46823682	0.053	NM_033151	ABCC11	ATP-binding cassette, sub-family C (CFTR/MRP), member 11
chr13_-_109600709	0.052		COL4A1	collagen, type IV, alpha 1
chr1_-_87152596	0.051	NM_004261 NM_203341	SEP15	15 kDa selenoprotein
chr10_-_45350804	0.051	NM_001002266	MARCH8	membrane-associated ring finger (C3HC4) 8
chr9_+_122923864	0.051		CEP110	centrosomal protein 110kDa
chr6_-_48186868	0.051		C6orf138	chromosome 6 open reading frame 138
chr17_-_31831093	0.049	NM_001123392 NM_032258	TBC1D3C TBC1D3G TBC1D3 TBC1D3H TBC1D3F	TBC1 domain family, member 3C TBC1 domain family, member 3G TBC1 domain family, member 3 TBC1 domain family, member 3H TBC1 domain family, member 3F
chr4_-_170314382	0.049		SH3RF1	SH3 domain containing ring finger 1
chr17_-_31528027	0.049	NM_001001417	TBC1D3B TBC1D3C TBC1D3G TBC1D3F	TBC1 domain family, member 3B TBC1 domain family, member 3C TBC1 domain family, member 3G TBC1 domain family, member 3F
chr4_+_130236731	0.048	NM_001099783	C4orf33	chromosome 4 open reading frame 33
chrX_-_138742050	0.046	NM_001010986 NM_173694	ATP11C	ATPase, class VI, type 11C
chr1_-_87152372	0.044		SEP15	15 kDa selenoprotein
chr16_-_11282595	0.044	NM_002761	PRM1	protamine 1
chr13_+_52500830	0.043	NM_006418	OLFM4	olfactomedin 4
chr11_-_4827013	0.042	NM_001004758	OR51S1	olfactory receptor, family 51, subfamily S, member 1
chr1_+_165564904	0.040	NM_001198783	POU2F1	POU class 2 homeobox 1
chr2_+_119416214	0.039	NM_006770	MARCO	macrophage receptor with collagenous structure
chr20_+_9236446	0.038	NM_000933	PLCB4	phospholipase C, beta 4
chr3_+_109498082	0.037		HHLA2	HERV-H LTR-associating 2
chrX_+_49718954	0.037	NM_000084	CLCN5	chloride channel 5
chr10_+_18280773	0.037	NM_001145195 NM_152725	SLC39A12	solute carrier family 39 (zinc transporter), member 12
chr10_-_7699192	0.036		ITIH5	inter-alpha (globulin) inhibitor H5
chr2_+_178893216	0.036	NM_145739	OSBPL6	oxysterol binding protein-like 6
chr11_-_5178505	0.034	NM_001004760	OR51V1	olfactory receptor, family 51, subfamily V, member 1
chr5_+_180399871	0.034		BTNL9	butyrophilin-like 9
chr1_-_89230844	0.034		RBMXL1 CCBL2	RNA binding motif protein, X-linked-like 1 cysteine conjugate-beta lyase 2
chr6_-_134415311	0.034	NM_145176	SLC2A12	solute carrier family 2 (facilitated glucose transporter), member 12
chr1_-_209732881	0.033	NM_001164688 NM_183059	RD3	retinal degeneration 3
chr9_+_123088217	0.033		GSN	gelsolin
chr6_+_167624792	0.033	NM_001143947 NM_018974	UNC93A	unc-93 homolog A (C. elegans)
chr1_+_93830169	0.033		LOC100129046	hypothetical LOC100129046
chr3_+_134601479	0.031	NM_003571	BFSP2	beaded filament structural protein 2, phakinin
chr15_+_63124760	0.030	NM_178859	OSTBETA	organic solute transporter beta
chr5_-_125956996	0.030		ALDH7A1	aldehyde dehydrogenase 7 family, member A1
chrX_+_52797004	0.030	NM_003147 NM_175698 NM_001164417	SSX2 SSX2B	synovial sarcoma, X breakpoint 2 synovial sarcoma, X breakpoint 2B
chr11_+_55617328	0.029	NM_001003750	OR8I2	olfactory receptor, family 8, subfamily I, member 2
chr12_+_119224506	0.028	NM_012240	SIRT4	sirtuin 4
chr1_-_161105174	0.028	NM_178550	C1orf110	chromosome 1 open reading frame 110
chr16_-_49742008	0.027	NM_001127892	SALL1	sal-like 1 (Drosophila)
chr19_+_54299686	0.027		SNRNP70	small nuclear ribonucleoprotein 70kDa (U1)
chr17_-_34209671	0.025	NM_003559	PIP4K2B	phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr2_+_38746742	0.025		GALM	galactose mutarotase (aldose 1-epimerase)
chr15_+_43331719	0.024	NM_004212	SLC28A2	solute carrier family 28 (sodium-coupled nucleoside transporter), member 2
chr4_+_187385618	0.024	NM_000892	KLKB1	kallikrein B, plasma (Fletcher factor) 1
chr14_-_20694023	0.024	NM_001004731	OR5AU1	olfactory receptor, family 5, subfamily AU, member 1
chr8_-_59575249	0.024	NM_000780	CYP7A1	cytochrome P450, family 7, subfamily A, polypeptide 1
chr8_-_7710547	0.023	NM_001037668 NM_001040705	DEFB107A DEFB107B	defensin, beta 107A defensin, beta 107B
chrX_-_130251068	0.023	NM_001170961 NM_001170962 NM_001555 NM_205833	IGSF1	immunoglobulin superfamily, member 1
chr3_-_195670256	0.021	NM_024524	ATP13A3	ATPase type 13A3
chrX_-_135783496	0.021
chrX_-_130250880	0.021		IGSF1	immunoglobulin superfamily, member 1
chr8_-_27525084	0.021	NM_001171138	CLU	clusterin
chr12_-_16321885	0.021	NM_001170798	SLC15A5	solute carrier family 15, member 5
chr12_+_103206625	0.021		TXNRD1	thioredoxin reductase 1
chr2_-_157890400	0.020	NM_020711	ERMN	ermin, ERM-like protein
chr6_-_155818728	0.020	NM_015718	NOX3	NADPH oxidase 3
chr17_-_33552166	0.020	NM_001123391 NM_032258	TBC1D3C TBC1D3G TBC1D3 TBC1D3F	TBC1 domain family, member 3C TBC1 domain family, member 3G TBC1 domain family, member 3 TBC1 domain family, member 3F
chr1_+_78888064	0.019	NM_006417	IFI44	interferon-induced protein 44
chr12_+_108035424	0.019
chr3_+_115495522	0.018	NM_173799	TIGIT	T cell immunoreceptor with Ig and ITIM domains
chr20_+_4650499	0.017	NM_012409	PRND	prion protein 2 (dublet)
chr1_-_245902965	0.017	NM_001005487	OR13G1	olfactory receptor, family 13, subfamily G, member 1
chr11_-_49960646	0.017	NM_001005270	OR4C12	olfactory receptor, family 4, subfamily C, member 12
chr10_+_83627422	0.016	NM_001165973	NRG3	neuregulin 3
chr19_-_62659665	0.015	NM_020633	VN1R1	vomeronasal 1 receptor 1
chr4_+_100714995	0.015		MTTP	microsomal triglyceride transfer protein
chr14_-_87806913	0.014	NM_138318	KCNK10	potassium channel, subfamily K, member 10
chr4_-_91979113	0.014	NM_183049	TMSL3	thymosin-like 3
chr21_-_30855478	0.014	NM_181614	KRTAP19-7	keratin associated protein 19-7
chr17_+_8154280	0.012	NM_173728	ARHGEF15	Rho guanine nucleotide exchange factor (GEF) 15
chrX_-_84250629	0.012	NM_001012980	SATL1	spermidine/spermine N1-acetyl transferase-like 1
chr5_+_180399830	0.012	NM_152547	BTNL9	butyrophilin-like 9
chr6_-_28591542	0.009	NM_182701	GPX6	glutathione peroxidase 6 (olfactory)
chrX_+_103243762	0.009	NM_001143978	ZCCHC18	zinc finger, CCHC domain containing 18
chr12_+_9925354	0.009	NM_001190765	KLRF2	killer cell lectin-like receptor subfamily F, member 2
chr17_-_36276987	0.009	NM_000223	KRT12	keratin 12
chr16_-_29514140	0.008
chr3_-_121117647	0.008		GSK3B	glycogen synthase kinase 3 beta
chr7_+_45033757	0.007	NM_001029835	CCM2	cerebral cavernous malformation 2
chr3_-_109730858	0.007	NM_014981	MYH15	myosin, heavy chain 15
chr5_+_121493113	0.006	NM_207317	ZNF474	zinc finger protein 474
chr2_-_215951161	0.005		FN1	fibronectin 1
chr8_+_7340777	0.005	NM_001037668 NM_001040705	DEFB107A DEFB107B	defensin, beta 107A defensin, beta 107B
chr4_+_71261066	0.004	NM_012390	SMR3B SMR3A	submaxillary gland androgen regulated protein 3B submaxillary gland androgen regulated protein 3A
chr11_+_4859624	0.004	NM_001004759	OR51T1	olfactory receptor, family 51, subfamily T, member 1
chr8_+_21972804	0.004		EPB49	erythrocyte membrane protein band 4.9 (dematin)
chr21_-_38792173	0.004	NM_001136155 NM_182918	ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr12_+_8557402	0.003	NM_080387	CLEC4D	C-type lectin domain family 4, member D
chr11_+_19328846	0.003	NM_001111018	NAV2	neuron navigator 2
chr1_-_13263334	0.002	NM_001012276	PRAMEF8 PRAMEF7	PRAME family member 8 PRAME family member 7
chr1_+_84382562	0.002		PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr22_+_29696662	0.002
chrX_-_48156287	0.001	NM_001034832 NM_001040612 NM_005636 NM_175729	SSX4B SSX4	synovial sarcoma, X breakpoint 4B synovial sarcoma, X breakpoint 4
chr3_-_129668780	0.001	NM_153330	DNAJB8	DnaJ (Hsp40) homolog, subfamily B, member 8
chr1_+_207944807	0.000	NM_005525	HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
12.17	5.55e-03	GO:0032313	regulation of Rab GTPase activity
12.17	5.55e-03	GO:0032483	regulation of Rab protein signal transduction
6.44	2.04e-02	GO:0032318	regulation of Ras GTPase activity
11.52	4.25e-02	GO:0031333	negative regulation of protein complex assembly

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
11.93	1.58e-03	GO:0005097	Rab GTPase activator activity