Motif ID: POU5F1.p2

Z-value: 1.556


Transcription factors associated with POU5F1.p2:

Gene SymbolEntrez IDGene Name
POU5F1 5460 POU class 5 homeobox 1



Activity profile for motif POU5F1.p2.

activity profile for motif POU5F1.p2


Sorted Z-values histogram for motif POU5F1.p2

Sorted Z-values for motif POU5F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_64922420 2.735 NM_002758
 MAP2K6
mitogen-activated protein kinase kinase 6
chr12_+_14409875 2.588 NM_018179
 ATF7IP
activating transcription factor 7 interacting protein
chrX_-_33267646 2.527 NM_000109
 DMD
dystrophin
chr3_-_64186151 2.463 NM_198859
 PRICKLE2
prickle homolog 2 (Drosophila)
chr13_-_101852028 1.965 NM_175929
 FGF14
fibroblast growth factor 14
chr10_+_68355797 1.753 NM_178011
 LRRTM3
leucine rich repeat transmembrane neuronal 3
chr7_-_76667045 1.668 NM_006682
 FGL2
fibrinogen-like 2
chr5_+_54491702 1.665 NM_001008397
 GPX8
glutathione peroxidase 8 (putative)
chr13_-_85271329 1.644 NM_032229
 SLITRK6
SLIT and NTRK-like family, member 6
chr1_+_161305188 1.470 NM_005613
 RGS4
regulator of G-protein signaling 4
chr12_-_48902692 1.432 NM_001113547
 LIMA1
LIM domain and actin binding 1
chr1_+_161305558 1.410 NM_001113381
 RGS4
regulator of G-protein signaling 4
chr16_-_3783475 1.391 CREBBP
CREB binding protein
chr18_-_45271938 1.383 RPL17-C18ORF32
RPL17
RPL17-C18orf32 read-through transcript
ribosomal protein L17
chrX_+_135397790 1.352 NM_001727
 BRS3
bombesin-like receptor 3
chr19_-_54835162 1.311 NM_006270
 RRAS
related RAS viral (r-ras) oncogene homolog
chr6_-_26151863 1.304 NM_021062
 HIST1H2BB
histone cluster 1, H2bb
chr1_-_215329569 1.291 NM_206594
NM_206595
 ESRRG

estrogen-related receptor gamma

chr1_+_81544432 1.169 LPHN2
latrophilin 2
chr3_-_58175437 1.158 NM_004944
 DNASE1L3
deoxyribonuclease I-like 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 61 entries
enrichment   p-value GO term description
3.24 6.94e-03 GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
1.97 2.17e-02 GO:0003002 regionalization
1.79 1.08e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.77 1.41e-04 GO:0051253 negative regulation of RNA metabolic process
1.77 1.46e-02 GO:0009792 embryo development ending in birth or egg hatching
1.77 1.99e-02 GO:0043009 chordate embryonic development
1.74 3.52e-02 GO:0060429 epithelium development
1.73 3.50e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.73 2.22e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.71 2.06e-04 GO:0045893 positive regulation of transcription, DNA-dependent
1.70 1.89e-02 GO:0032583 regulation of gene-specific transcription
1.67 2.52e-04 GO:0010628 positive regulation of gene expression
1.66 1.83e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.66 1.92e-03 GO:0010629 negative regulation of gene expression
1.65 6.06e-04 GO:0031327 negative regulation of cellular biosynthetic process
1.65 1.75e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.64 1.52e-06 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.64 1.72e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.62 4.47e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.61 1.71e-03 GO:0009890 negative regulation of biosynthetic process

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.55 5.69e-03 GO:0030054 cell junction
1.17 3.80e-04 GO:0005634 nucleus
1.16 4.40e-02 GO:0005886 plasma membrane
1.16 4.47e-02 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
3.43 1.13e-03 GO:0003707 steroid hormone receptor activity
3.24 2.90e-03 GO:0004879 ligand-dependent nuclear receptor activity
1.69 8.67e-06 GO:0043565 sequence-specific DNA binding
1.66 2.97e-08 GO:0001071 nucleic acid binding transcription factor activity
1.66 2.97e-08 GO:0003700 sequence-specific DNA binding transcription factor activity
1.54 2.44e-05 GO:0030528 transcription regulator activity
1.40 4.00e-08 GO:0003677 DNA binding
1.27 2.24e-05 GO:0003676 nucleic acid binding
1.27 1.75e-02 GO:0008270 zinc ion binding