Motif ID: RREB1.p2

Z-value: 1.540


Transcription factors associated with RREB1.p2:

Gene SymbolEntrez IDGene Name
RREB1 6239 ras responsive element binding protein 1



Activity profile for motif RREB1.p2.

activity profile for motif RREB1.p2


Sorted Z-values histogram for motif RREB1.p2

Sorted Z-values for motif RREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RREB1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr20_-_22512893 2.458 FOXA2
forkhead box A2
chr3_+_187917791 2.011 NM_000893
NM_001102416
NM_001166451
 KNG1


kininogen 1


chr2_+_233443237 1.955 NM_206895
 C2orf82
chromosome 2 open reading frame 82
chr20_-_22513050 1.822 NM_021784
 FOXA2
forkhead box A2
chr14_-_36059084 1.557 NM_001079668
 NKX2-1
NK2 homeobox 1
chr22_-_30929463 1.544 NM_001098527
 RFPL2
ret finger protein-like 2
chrX_+_17665483 1.266 NM_001037535
NM_001037536
NM_001037540
NM_006746
 SCML1



sex comb on midleg-like 1 (Drosophila)



chr8_-_139995417 1.214 NM_152888
 COL22A1
collagen, type XXII, alpha 1
chr20_+_44070946 1.138 NM_004994
 MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr20_-_51644187 1.125 ZNF217
zinc finger protein 217
chr11_+_10428799 1.059 NM_000480
 AMPD3
adenosine monophosphate deaminase 3
chr2_+_72998111 0.877 NM_004097
 EMX1
empty spiracles homeobox 1
chr16_-_3225070 0.867 NM_001145447
NM_003454
 ZNF200

zinc finger protein 200

chr20_-_49592444 0.864 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr16_-_10183616 0.853 NM_001134407
 GRIN2A
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
chr3_+_50629593 0.844 MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr6_-_29703725 0.834 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr6_-_32659958 0.802 HLA-DRB1
HLA-DRB5
major histocompatibility complex, class II, DR beta 1
major histocompatibility complex, class II, DR beta 5
chr1_+_3378030 0.801 ARHGEF16
Rho guanine nucleotide exchange factor (GEF) 16
chr3_-_10522267 0.780 NM_001001331
NM_001683
 ATP2B2

ATPase, Ca++ transporting, plasma membrane 2


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 76 entries
enrichment   p-value GO term description
1.90 1.36e-02 GO:0042692 muscle cell differentiation
1.64 8.60e-03 GO:0045596 negative regulation of cell differentiation
1.62 3.86e-02 GO:0050767 regulation of neurogenesis
1.61 2.91e-03 GO:0060284 regulation of cell development
1.55 5.42e-03 GO:0007420 brain development
1.54 3.73e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.54 4.32e-02 GO:0032940 secretion by cell
1.53 1.75e-06 GO:0045595 regulation of cell differentiation
1.53 4.89e-02 GO:0051093 negative regulation of developmental process
1.52 2.49e-03 GO:0007268 synaptic transmission
1.51 2.76e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.48 3.24e-03 GO:0007417 central nervous system development
1.48 5.01e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.47 6.92e-03 GO:0019226 transmission of nerve impulse
1.47 6.92e-03 GO:0035637 multicellular organismal signaling
1.45 1.98e-03 GO:0009887 organ morphogenesis
1.45 1.47e-02 GO:0000904 cell morphogenesis involved in differentiation
1.43 2.55e-06 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.43 3.92e-02 GO:0048858 cell projection morphogenesis
1.41 4.12e-02 GO:0045892 negative regulation of transcription, DNA-dependent

Gene overrepresentation in compartment category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
1.81 2.54e-03 GO:0005912 adherens junction
1.73 6.97e-03 GO:0070161 anchoring junction
1.62 4.74e-03 GO:0016323 basolateral plasma membrane
1.44 2.10e-04 GO:0030054 cell junction
1.31 1.35e-02 GO:0005624 membrane fraction
1.28 4.93e-02 GO:0005626 insoluble fraction
1.19 8.32e-03 GO:0005829 cytosol
1.17 1.29e-03 GO:0043234 protein complex
1.14 5.11e-06 GO:0005634 nucleus
1.06 2.15e-04 GO:0044424 intracellular part
1.06 2.52e-04 GO:0005622 intracellular
1.06 1.66e-02 GO:0043226 organelle
1.06 1.91e-02 GO:0043229 intracellular organelle

Gene overrepresentation in function category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
1.77 9.81e-04 GO:0003682 chromatin binding
1.75 2.17e-02 GO:0008022 protein C-terminus binding
1.71 4.12e-03 GO:0010843 promoter binding
1.64 1.82e-02 GO:0000975 regulatory region DNA binding
1.64 1.82e-02 GO:0001067 regulatory region nucleic acid binding
1.64 1.82e-02 GO:0044212 transcription regulatory region DNA binding
1.50 6.61e-04 GO:0019904 protein domain specific binding
1.48 2.80e-06 GO:0043565 sequence-specific DNA binding
1.35 1.34e-04 GO:0030528 transcription regulator activity
1.33 4.47e-04 GO:0001071 nucleic acid binding transcription factor activity
1.33 4.47e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.18 2.95e-17 GO:0005515 protein binding
1.07 2.57e-07 GO:0005488 binding