Motif ID: RXR{A,B,G}.p2

Z-value: 1.372


Transcription factors associated with RXR{A,B,G}.p2:

Gene SymbolEntrez IDGene Name
RXRA 6256 retinoid X receptor, alpha
RXRB 6257 retinoid X receptor, beta
RXRG 6258 retinoid X receptor, gamma



Activity profile for motif RXR{A,B,G}.p2.

activity profile for motif RXR{A,B,G}.p2


Sorted Z-values histogram for motif RXR{A,B,G}.p2

Sorted Z-values for motif RXR{A,B,G}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RXR{A,B,G}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_24602995 2.046 ALDH5A1
aldehyde dehydrogenase 5 family, member A1
chr11_+_65162114 1.801 NM_006747
 SIPA1
signal-induced proliferation-associated 1
chr22_+_18085891 1.703 SEPT5
septin 5
chr6_+_24603145 1.672 NM_001080
NM_170740
 ALDH5A1

aldehyde dehydrogenase 5 family, member A1

chr11_-_62136778 1.667 NM_153265
 EML3
echinoderm microtubule associated protein like 3
chr22_+_18085990 1.574 SEPT5-GP1BB
SEPT5
SEPT5-GP1BB read-through transcript
septin 5
chr11_+_75157450 1.236 DGAT2
diacylglycerol O-acyltransferase 2
chr11_+_62136788 1.212 NM_000327
 ROM1
retinal outer segment membrane protein 1
chr20_+_48032918 1.197 NM_005985
 SNAI1
snail homolog 1 (Drosophila)
chr11_-_75595098 1.130 NM_004626
 WNT11
wingless-type MMTV integration site family, member 11
chr11_-_63440891 1.125 NM_173587
 RCOR2
REST corepressor 2
chr11_+_14621972 1.091 PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr22_+_18081968 1.080 NM_002688
 SEPT5
septin 5
chr17_-_33179118 1.071 NM_000458
NM_001165923
 HNF1B

HNF1 homeobox B

chr17_-_33178987 1.064 HNF1B
HNF1 homeobox B
chr3_-_48573556 1.053 PFKFB4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr6_-_167289659 1.052


chr10_+_76256305 1.012 NM_012330
 MYST4
MYST histone acetyltransferase (monocytic leukemia) 4
chr4_+_134292630 1.012 PCDH10
protocadherin 10
chr17_+_40192072 1.010 NM_002390
 ADAM11
ADAM metallopeptidase domain 11

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 35 entries
enrichment   p-value GO term description
1.73 8.06e-03 GO:0071495 cellular response to endogenous stimulus
1.70 4.07e-02 GO:0032870 cellular response to hormone stimulus
1.65 3.45e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.58 4.46e-02 GO:0032583 regulation of gene-specific transcription
1.57 3.28e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.56 1.04e-06 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.54 5.73e-03 GO:0009725 response to hormone stimulus
1.53 2.99e-03 GO:0009719 response to endogenous stimulus
1.51 6.62e-03 GO:0010628 positive regulation of gene expression
1.51 1.38e-02 GO:0045893 positive regulation of transcription, DNA-dependent
1.46 1.90e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.43 3.38e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.36 4.87e-02 GO:0010646 regulation of cell communication
1.32 2.86e-02 GO:0009966 regulation of signal transduction
1.30 3.90e-04 GO:0048523 negative regulation of cellular process
1.29 4.46e-02 GO:0023051 regulation of signaling
1.27 9.84e-04 GO:0048519 negative regulation of biological process
1.26 2.59e-03 GO:0048522 positive regulation of cellular process
1.25 1.38e-02 GO:0051252 regulation of RNA metabolic process
1.24 4.44e-03 GO:0048518 positive regulation of biological process

Gene overrepresentation in compartment category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
1.42 9.83e-03 GO:0031975 envelope
1.40 2.53e-02 GO:0031967 organelle envelope
1.20 4.91e-02 GO:0031974 membrane-enclosed lumen
1.13 2.63e-03 GO:0044444 cytoplasmic part
1.10 4.11e-04 GO:0043231 intracellular membrane-bounded organelle
1.10 4.29e-04 GO:0043227 membrane-bounded organelle
1.10 3.61e-03 GO:0005737 cytoplasm
1.08 1.07e-02 GO:0043229 intracellular organelle
1.08 1.09e-02 GO:0043226 organelle
1.07 9.31e-04 GO:0044424 intracellular part
1.06 4.38e-03 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.74 1.45e-03 GO:0016563 transcription activator activity
1.43 2.03e-02 GO:0043565 sequence-specific DNA binding
1.40 1.96e-03 GO:0001071 nucleic acid binding transcription factor activity
1.40 1.96e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.38 4.20e-03 GO:0030528 transcription regulator activity
1.14 1.27e-05 GO:0005515 protein binding
1.06 4.86e-02 GO:0005488 binding