Motif ID: SOX2.p2

Z-value: 1.084


Transcription factors associated with SOX2.p2:

Gene SymbolEntrez IDGene Name
SOX2 6657 SRY (sex determining region Y)-box 2



Activity profile for motif SOX2.p2.

activity profile for motif SOX2.p2


Sorted Z-values histogram for motif SOX2.p2

Sorted Z-values for motif SOX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_110968594 1.784 NM_006583
 RRH
retinal pigment epithelium-derived rhodopsin homolog
chr6_-_128263868 1.603 NM_001010923
NM_001164685
 THEMIS

thymocyte selection associated

chr17_-_1195096 1.526 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr4_-_101658094 1.439 NM_001159694
NM_016242
 EMCN

endomucin

chr3_-_150533948 1.244 NM_001184723
NM_138786
 TM4SF18

transmembrane 4 L six family member 18

chr3_-_150422474 1.217 NM_000096
 CP
ceruloplasmin (ferroxidase)
chr5_+_140460240 1.175 NM_018937
 PCDHB3
protocadherin beta 3
chr1_-_197173159 1.173 LOC100131234
familial acute myelogenous leukemia related factor
chr3_+_142587973 1.087


chr10_-_32707549 1.081 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr5_+_140454382 0.993 NM_018936
 PCDHB2
protocadherin beta 2
chr14_-_64479198 0.951 NM_002083
 GPX2
glutathione peroxidase 2 (gastrointestinal)
chr7_+_106897737 0.949 NM_005295
 GPR22
G protein-coupled receptor 22
chr15_+_49760841 0.930 NM_001165257
NM_013243
 SCG3

secretogranin III

chr6_-_130072971 0.907 NM_033515
 ARHGAP18
Rho GTPase activating protein 18
chr9_+_112470871 0.896 NM_001166280
NM_001166281
NM_005592
 MUSK


muscle, skeletal, receptor tyrosine kinase


chr12_+_79362256 0.892 NM_001145026
 PTPRQ
protein tyrosine phosphatase, receptor type, Q
chr3_+_182900081 0.889 SOX2OT
SOX2 overlapping transcript (non-protein coding)
chr10_-_62002672 0.863 ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr2_-_165768798 0.846 NM_001081676
NM_001081677
NM_006922
 SCN3A


sodium channel, voltage-gated, type III, alpha subunit



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
3.87 4.73e-03 GO:0016339 calcium-dependent cell-cell adhesion
2.43 3.67e-06 GO:0007156 homophilic cell adhesion
1.76 2.30e-03 GO:0030029 actin filament-based process
1.76 1.47e-02 GO:0030036 actin cytoskeleton organization
1.33 1.41e-03 GO:0007399 nervous system development
1.21 4.65e-04 GO:0007275 multicellular organismal development
1.20 1.82e-02 GO:0048731 system development
1.19 2.02e-02 GO:0048856 anatomical structure development
1.18 8.35e-06 GO:0032501 multicellular organismal process
1.18 2.17e-03 GO:0032502 developmental process

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
2.65 4.01e-02 GO:0008013 beta-catenin binding
2.57 4.14e-02 GO:0005070 SH3/SH2 adaptor activity
2.43 2.99e-02 GO:0035591 signaling adaptor activity