Motif ID: SP1.p2

Z-value: 0.917


Transcription factors associated with SP1.p2:

Gene SymbolEntrez IDGene Name
SP1 6667 Sp1 transcription factor



Activity profile for motif SP1.p2.

activity profile for motif SP1.p2


Sorted Z-values histogram for motif SP1.p2

Sorted Z-values for motif SP1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SP1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_63829616 5.000 NM_004451
ESRRA
estrogen-related receptor alpha
chr1_-_32574185 4.342 NM_023009
MARCKSL1
MARCKS-like 1
chr1_-_40903897 4.325 NM_014747
RIMS3
regulating synaptic membrane exocytosis 3
chr1_-_40903700 3.949 RIMS3
regulating synaptic membrane exocytosis 3
chr19_-_55524445 3.862 NM_004977
KCNC3
potassium voltage-gated channel, Shaw-related subfamily, member 3
chr20_+_1154763 3.374 NM_001136566
RAD21L1
RAD21-like 1 (S. pombe)
chr16_-_8870343 3.328 NM_014316
CARHSP1
calcium regulated heat stable protein 1, 24kDa
chr16_-_88295595 3.257 NM_152339
SPATA2L
spermatogenesis associated 2-like
chr20_-_3102169 3.216 ProSAPiP1
ProSAPiP1 protein
chr21_+_42946719 3.010 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A



















chr6_-_31805547 2.939 DDAH2
dimethylarginine dimethylaminohydrolase 2
chr20_-_51644187 2.891 ZNF217
zinc finger protein 217
chr17_+_77582774 2.781 NM_005052
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr2_+_46623396 2.746 RHOQ
ras homolog gene family, member Q
chr21_-_44583696 2.732 NM_004928
C21orf2
chromosome 21 open reading frame 2
chr1_+_27925054 2.677 NM_001143912
NM_001143913
NM_001143914
NM_001143915
NM_152660
FAM76A




family with sequence similarity 76, member A




chr17_+_52266451 2.647 NM_003647
DGKE
diacylglycerol kinase, epsilon 64kDa
chr6_+_7052798 2.566 NM_001168344
RREB1
ras responsive element binding protein 1
chr19_+_659766 2.553 NM_001040134
NM_002579
PALM

paralemmin

chr21_-_44583662 2.538 C21orf2
chromosome 21 open reading frame 2
chr8_+_144706699 2.514 NM_001166237
GSDMD
gasdermin D
chr22_+_20101661 2.495 NM_015094
HIC2
hypermethylated in cancer 2
chr22_-_21231421 2.465 NM_206955
NM_206956
NM_006115
NM_206953
NM_206954
PRAME




preferentially expressed antigen in melanoma




chr10_+_76256305 2.453 NM_012330
MYST4
MYST histone acetyltransferase (monocytic leukemia) 4
chr22_-_20419975 2.417 NM_013313
YPEL1
yippee-like 1 (Drosophila)
chr8_-_144722141 2.414 C8orf73
chromosome 8 open reading frame 73
chr3_+_47004457 2.374 NBEAL2
neurobeachin-like 2
chr9_+_132961723 2.353 AIF1L
allograft inflammatory factor 1-like
chr20_-_62151216 2.304 NM_018419
SOX18
SRY (sex determining region Y)-box 18
chr5_-_175969697 2.273 NM_052899
GPRIN1
G protein regulated inducer of neurite outgrowth 1
chr3_+_173240983 2.261 NM_001135095
FNDC3B
fibronectin type III domain containing 3B
chr12_-_123617962 2.239 NM_001077261
NM_006312
NCOR2

nuclear receptor corepressor 2

chr3_-_38041281 2.229 NM_001130964
PLCD1
phospholipase C, delta 1
chr19_-_60350122 2.207 TNNT1
troponin T type 1 (skeletal, slow)
chr17_-_24062998 2.201 NM_152465
PROCA1
protein interacting with cyclin A1
chr19_+_54786723 2.192 NM_020719
PRR12
proline rich 12
chr5_+_176446425 2.184 NM_002011
NM_213647
FGFR4

fibroblast growth factor receptor 4

chr9_-_122679387 2.138 NM_001009936
NM_015651
PHF19

PHD finger protein 19

chr6_-_31805932 2.107 DDAH2
dimethylarginine dimethylaminohydrolase 2
chr6_-_31806012 2.095 NM_013974
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr12_+_119562737 2.042 NM_001033677
CABP1
calcium binding protein 1
chr16_-_65287967 2.035 NM_178818
NM_181521
CMTM4

CKLF-like MARVEL transmembrane domain containing 4

chr19_+_12805747 1.979 MAST1
microtubule associated serine/threonine kinase 1
chr6_+_34312979 1.946 HMGA1
high mobility group AT-hook 1
chr19_-_60350118 1.943 TNNT1
troponin T type 1 (skeletal, slow)
chr2_+_46623325 1.940 NM_012249
RHOQ
ras homolog gene family, member Q
chr9_-_122679283 1.936 PHF19
PHD finger protein 19
chr16_+_29373365 1.933 NM_001014999
NM_001015000
NM_024044
NM_178044
SLX1A-SULT1A3
SLX1A

SLX1B

SLX1A-SULT1A3 read-through transcript
SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)

SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)

chr17_-_77421980 1.931 NM_001185077
ARHGDIA
Rho GDP dissociation inhibitor (GDI) alpha
chr17_-_34157962 1.898 NM_007144
PCGF2
polycomb group ring finger 2
chr22_-_17546296 1.870 NM_005984
SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr1_+_945331 1.825 NM_198576
AGRN
agrin
chr19_-_47619992 1.809 LIPE
lipase, hormone-sensitive
chr17_-_75427644 1.807 NM_003655
CBX4
chromobox homolog 4
chr1_-_1840564 1.801 NM_178545
TMEM52
transmembrane protein 52
chr7_-_4889772 1.799 NM_018059
RADIL
Ras association and DIL domains
chr8_-_146023228 1.789 LOC100130027
hypothetical LOC100130027
chr22_-_18807805 1.788 PI4KAP2
PI4KAP1
phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 2
phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 1
chr2_+_112372671 1.785 MERTK
c-mer proto-oncogene tyrosine kinase
chr9_+_138680064 1.783 EGFL7
EGF-like-domain, multiple 7
chr1_+_945399 1.782


chr19_+_59064471 1.764 NM_001020821
NM_001020818
MYADM

myeloid-associated differentiation marker

chr16_+_1143241 1.754 NM_001005407
NM_021098
CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

chr7_-_86526880 1.742 NM_001142749
KIAA1324L
KIAA1324-like
chr9_+_132961683 1.735 NM_001185095
NM_001185096
NM_031426
AIF1L


allograft inflammatory factor 1-like


chr8_-_71478041 1.733 NCOA2
nuclear receptor coactivator 2
chr7_+_64136078 1.731 CCT6P3
chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3
chr20_-_61600834 1.730 NM_001958
EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chr20_+_44083667 1.721 NM_001134771
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr21_-_44583505 1.706 C21orf2
chromosome 21 open reading frame 2
chr8_-_124355670 1.702 NM_001017926
NM_007222
ZHX1

zinc fingers and homeoboxes 1

chr1_-_52791309 1.693 NM_001009881
NM_015269
ZCCHC11

zinc finger, CCHC domain containing 11

chr11_+_45900731 1.692 GYLTL1B
glycosyltransferase-like 1B
chrX_+_9392980 1.687 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr19_+_45389356 1.677 NM_002446
MAP3K10
mitogen-activated protein kinase kinase kinase 10
chr6_-_18263262 1.675 NM_000367
TPMT
thiopurine S-methyltransferase
chr22_-_17546276 1.673 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr14_+_104337923 1.659 NM_001137601
ZBTB42
zinc finger and BTB domain containing 42
chr6_+_34313007 1.655 HMGA1
high mobility group AT-hook 1
chr19_-_43570503 1.653 NM_152657
GGN
gametogenetin
chr22_+_19649417 1.646 NM_001018060
NM_144704
AIFM3

apoptosis-inducing factor, mitochondrion-associated, 3

chr22_-_17545872 1.639 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr19_-_54636425 1.635 NM_020309
SLC17A7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr8_-_145609737 1.634 SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr19_-_45642078 1.633 NM_203344
SERTAD3
SERTA domain containing 3
chr1_+_945472 1.631 AGRN
agrin
chr5_-_176671897 1.621 NM_001142935
NM_031300
MXD3

MAX dimerization protein 3

chr22_-_18635614 1.620 NM_023004
RTN4R
reticulon 4 receptor
chr1_-_39910296 1.617 NM_032526
NT5C1A
5'-nucleotidase, cytosolic IA
chr8_-_144722027 1.613 C8orf73
chromosome 8 open reading frame 73
chr19_+_59064795 1.601 MYADM
myeloid-associated differentiation marker
chr22_-_20551722 1.592 MAPK1
mitogen-activated protein kinase 1
chr22_+_18085891 1.591 SEPT5
septin 5
chr17_-_39556535 1.589 NM_001015053
NM_005474
HDAC5

histone deacetylase 5

chr12_-_112057650 1.584 NM_001193521
RASAL1
RAS protein activator like 1 (GAP1 like)
chr2_+_112372651 1.573 NM_006343
MERTK
c-mer proto-oncogene tyrosine kinase
chr18_+_75256702 1.572 NM_006162
NM_172388
NM_172390
NFATC1


nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1


chr11_-_69228286 1.564 NM_005117
FGF19
fibroblast growth factor 19
chr11_+_64705989 1.562 CAPN1
calpain 1, (mu/I) large subunit
chr19_-_3013191 1.553 NM_001130
NM_198970
AES

amino-terminal enhancer of split

chr1_+_243200275 1.543 EFCAB2
EF-hand calcium binding domain 2
chr2_+_69995656 1.541 NM_002357
MXD1
MAX dimerization protein 1
chr22_+_18081968 1.540 NM_002688
SEPT5
septin 5
chr22_-_17546234 1.538 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr19_-_10540620 1.537 NM_001800
NM_079421
CDKN2D

cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)

chr1_+_46485946 1.533 NM_001142548
NM_003579
RAD54L

RAD54-like (S. cerevisiae)

chr3_-_185461768 1.532 NM_033259
CAMK2N2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr6_+_7052985 1.532 NM_001003698
NM_001003699
NM_001003700
RREB1


ras responsive element binding protein 1


chr6_-_31890765 1.514 NM_005527
HSPA1L
heat shock 70kDa protein 1-like
chr16_-_1404635 1.512 NM_001037125
NM_001193388
UNKL

unkempt homolog (Drosophila)-like

chr20_+_34357604 1.510 DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr9_+_70509925 1.504 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr17_-_34015631 1.500 NM_025248
SRCIN1
SRC kinase signaling inhibitor 1
chr1_-_203579932 1.493 KLHDC8A
kelch domain containing 8A
chr8_-_144887876 1.488 NM_198488
FAM83H
family with sequence similarity 83, member H
chr1_-_1699723 1.487 NM_023018
NADK
NAD kinase
chr12_-_46499834 1.485 NM_001098416
NM_015401
HDAC7

histone deacetylase 7

chr22_+_18085990 1.484 SEPT5-GP1BB
SEPT5
SEPT5-GP1BB read-through transcript
septin 5
chrX_+_138060 1.482 NM_018390
PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr19_+_50702525 1.481 NM_003370
VASP
vasodilator-stimulated phosphoprotein
chr1_+_46486020 1.477 RAD54L
RAD54-like (S. cerevisiae)
chr19_-_45416112 1.475 NM_152479
TTC9B
tetratricopeptide repeat domain 9B
chr6_-_35572694 1.469 NM_003214
TEAD3
TEA domain family member 3
chr8_-_145661545 1.468 NM_032687
NM_001129888
CYHR1

cysteine/histidine-rich 1

chr19_-_18409788 1.468 NM_001170939
ISYNA1
inositol-3-phosphate synthase 1
chr11_+_359723 1.467 NM_178537
B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr6_+_34313347 1.465 HMGA1
high mobility group AT-hook 1
chr1_+_32979930 1.459 NM_020888
KIAA1522
KIAA1522
chr22_-_18384251 1.443 NM_001670
ARVCF
armadillo repeat gene deleted in velocardiofacial syndrome
chr3_-_38040999 1.438 PLCD1
phospholipase C, delta 1
chr4_+_1330957 1.431 NM_020894
KIAA1530
KIAA1530
chr1_+_243200251 1.430 NM_001143943
EFCAB2
EF-hand calcium binding domain 2
chr4_+_995395 1.428 FGFRL1
fibroblast growth factor receptor-like 1
chr14_+_102659464 1.426 TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr17_+_24944605 1.424 NM_152345
ANKRD13B
ankyrin repeat domain 13B
chr6_+_33495824 1.421 NM_006772
SYNGAP1
synaptic Ras GTPase activating protein 1
chr5_+_172193826 1.416 NM_001031711
ERGIC1
endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr12_+_110328126 1.416 NM_005475
SH2B3
SH2B adaptor protein 3
chr7_-_97868101 1.414 BAIAP2L1
BAI1-associated protein 2-like 1
chr3_+_157071173 1.403 GMPS
guanine monphosphate synthetase
chr16_+_2016807 1.402 NM_001130012
NM_004785
SLC9A3R2

solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2

chr1_-_23683214 1.399 ASAP3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr19_+_540849 1.391 NM_001194
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr1_+_199259664 1.387


chr17_+_75366524 1.383 NM_005189
NM_032647
CBX2

chromobox homolog 2

chr14_-_36059084 1.383 NM_001079668
NKX2-1
NK2 homeobox 1
chr9_+_108665168 1.377 NM_021224
ZNF462
zinc finger protein 462
chr18_-_43711452 1.372 NM_001003652
NM_001135937
SMAD2

SMAD family member 2

chr1_-_21868380 1.372 NM_001145657
NM_002885
RAP1GAP

RAP1 GTPase activating protein

chr19_+_50692325 1.366


chr2_-_70848621 1.358 NM_001185055
NM_001617
NM_017482
NM_017488
ADD2



adducin 2 (beta)



chr1_+_9217444 1.358 NM_004285
H6PD
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chrX_+_118254233 1.351 NM_006667
PGRMC1
progesterone receptor membrane component 1
chr19_+_45996881 1.350 NM_080732
EGLN2
egl nine homolog 2 (C. elegans)
chr19_-_3013441 1.346 AES
amino-terminal enhancer of split
chr1_+_9217384 1.346 H6PD
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr12_+_55896844 1.344 NM_007224
NXPH4
neurexophilin 4
chr5_+_154115046 1.342 LARP1
La ribonucleoprotein domain family, member 1
chr21_+_34367678 1.337 NM_032476
NM_006933
MRPS6
SLC5A3
mitochondrial ribosomal protein S6
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
chr7_-_97868362 1.334 NM_018842
BAIAP2L1
BAI1-associated protein 2-like 1
chr19_+_868285 1.332 NM_032551
KISS1R
KISS1 receptor
chr1_+_210525397 1.324 PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr2_+_10360471 1.322 NM_002149
HPCAL1
hippocalcin-like 1
chr2_+_136005423 1.320 NM_015361
R3HDM1
R3H domain containing 1
chr17_-_39556483 1.319 HDAC5
histone deacetylase 5
chr22_-_17659183 1.316 NM_001835
NM_007098
CLTCL1

clathrin, heavy chain-like 1

chr6_+_3204184 1.316 PSMG4
proteasome (prosome, macropain) assembly chaperone 4
chr8_+_126511739 1.313 NM_025195
TRIB1
tribbles homolog 1 (Drosophila)
chr22_+_19649460 1.312 AIFM3
apoptosis-inducing factor, mitochondrion-associated, 3
chr5_+_140997171 1.310 RELL2
RELT-like 2
chr9_+_130142607 1.303 NM_005094
SLC27A4
solute carrier family 27 (fatty acid transporter), member 4
chr16_+_2504001 1.301 ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr10_-_43224312 1.300 NM_001098205
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr1_-_36624071 1.300 NM_032017
STK40
serine/threonine kinase 40
chr3_-_50624114 1.298 NM_013324
NM_145071
CISH

cytokine inducible SH2-containing protein

chr19_-_47450991 1.298 ERF
Ets2 repressor factor
chr18_+_75256931 1.297 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr9_-_100510657 1.296 NM_005458
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr6_+_33486750 1.295 NM_002636
NM_024165
PHF1

PHD finger protein 1

chr6_+_33046636 1.294 NM_001113182
BRD2
bromodomain containing 2
chr19_-_13977875 1.289 RFX1
regulatory factor X, 1 (influences HLA class II expression)
chr1_+_46485972 1.287 RAD54L
RAD54-like (S. cerevisiae)
chr11_-_64167361 1.280 NM_138734
NRXN2
neurexin 2
chr1_+_210525792 1.278 PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr3_-_48569213 1.270 NM_004567
PFKFB4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr7_+_73080362 1.264 NM_000501
NM_001081752
NM_001081753
NM_001081754
NM_001081755
ELN




elastin




chr6_-_29703913 1.263 NM_021903
GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr4_+_52403922 1.263 NM_001040402
NM_015115
DCUN1D4

DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)

chr22_+_21742364 1.261 NM_002073
GNAZ
guanine nucleotide binding protein (G protein), alpha z polypeptide
chr7_-_100262971 1.256 NM_004444
EPHB4
EPH receptor B4
chr16_+_4948318 1.249 NM_014692
SEC14L5
SEC14-like 5 (S. cerevisiae)
chr16_+_31036474 1.247 NM_032188
NM_182958
MYST1

MYST histone acetyltransferase 1

chr17_-_76622967 1.241 FLJ90757
hypothetical LOC440465
chr11_+_131286513 1.236 NTM
neurotrimin
chr3_+_31549123 1.233 STT3B
STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
chr16_+_1143738 1.231 CACNA1H
calcium channel, voltage-dependent, T type, alpha 1H subunit
chr6_+_33046706 1.231 BRD2
bromodomain containing 2
chr16_+_83618804 1.231 NM_014732
KIAA0513
KIAA0513
chr5_-_121440704 1.227 NM_001178102
LOX
lysyl oxidase
chr19_-_17306538 1.224 NM_020959
ANO8
anoctamin 8

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.07 2.66e-22 GO:0009987 cellular process
1.12 2.15e-19 GO:0044237 cellular metabolic process
1.13 6.94e-15 GO:0044260 cellular macromolecule metabolic process
1.09 5.98e-13 GO:0008152 metabolic process
1.08 1.88e-12 GO:0065007 biological regulation
1.09 1.93e-12 GO:0050789 regulation of biological process
1.10 2.17e-12 GO:0044238 primary metabolic process
1.09 1.52e-11 GO:0050794 regulation of cellular process
1.12 1.82e-10 GO:0019222 regulation of metabolic process
1.13 2.13e-10 GO:0031323 regulation of cellular metabolic process
1.16 3.76e-10 GO:0048519 negative regulation of biological process
1.13 4.37e-10 GO:0080090 regulation of primary metabolic process
1.13 6.79e-10 GO:0060255 regulation of macromolecule metabolic process
1.17 1.03e-09 GO:0048523 negative regulation of cellular process
1.10 2.10e-09 GO:0043170 macromolecule metabolic process
1.13 3.29e-09 GO:0016043 cellular component organization
1.18 4.70e-09 GO:0006464 protein modification process
1.14 4.81e-08 GO:0071842 cellular component organization at cellular level
1.17 5.38e-08 GO:0043412 macromolecule modification
1.14 7.76e-08 GO:0044267 cellular protein metabolic process
1.12 9.28e-08 GO:0071840 cellular component organization or biogenesis
1.15 1.17e-07 GO:0044249 cellular biosynthetic process
1.14 1.20e-07 GO:0009058 biosynthetic process
1.12 1.23e-07 GO:0006807 nitrogen compound metabolic process
1.13 1.51e-07 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.12 1.86e-07 GO:0034641 cellular nitrogen compound metabolic process
1.14 4.36e-07 GO:0010468 regulation of gene expression
1.13 8.85e-07 GO:0071841 cellular component organization or biogenesis at cellular level
1.14 1.76e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.24 5.07e-06 GO:0022402 cell cycle process
1.21 9.95e-06 GO:0007049 cell cycle
1.16 1.30e-05 GO:0034645 cellular macromolecule biosynthetic process
1.16 1.30e-05 GO:0009059 macromolecule biosynthetic process
1.13 1.97e-05 GO:0010556 regulation of macromolecule biosynthetic process
1.12 2.09e-05 GO:0048518 positive regulation of biological process
1.13 2.21e-05 GO:0051252 regulation of RNA metabolic process
1.12 2.57e-05 GO:0031326 regulation of cellular biosynthetic process
1.17 2.75e-05 GO:0007399 nervous system development
1.13 2.81e-05 GO:0048522 positive regulation of cellular process
1.20 3.30e-05 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.24 4.78e-05 GO:0022403 cell cycle phase
1.12 5.22e-05 GO:0051171 regulation of nitrogen compound metabolic process
1.12 5.90e-05 GO:0009889 regulation of biosynthetic process
1.13 7.66e-05 GO:0048869 cellular developmental process
1.09 7.92e-05 GO:0032502 developmental process
1.12 9.25e-05 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.20 1.25e-04 GO:0022008 neurogenesis
1.20 1.31e-04 GO:0032774 RNA biosynthetic process
1.13 1.33e-04 GO:0006355 regulation of transcription, DNA-dependent
1.20 1.52e-04 GO:0010605 negative regulation of macromolecule metabolic process
1.13 1.93e-04 GO:0090304 nucleic acid metabolic process
1.15 2.23e-04 GO:0006996 organelle organization
1.25 2.46e-04 GO:0000278 mitotic cell cycle
1.19 3.57e-04 GO:0009892 negative regulation of metabolic process
1.17 3.60e-04 GO:0010604 positive regulation of macromolecule metabolic process
1.19 3.93e-04 GO:0032268 regulation of cellular protein metabolic process
1.13 4.35e-04 GO:0030154 cell differentiation
1.20 4.40e-04 GO:0006351 transcription, DNA-dependent
1.24 4.45e-04 GO:0000902 cell morphogenesis
1.09 4.95e-04 GO:0007275 multicellular organismal development
1.20 6.10e-04 GO:0048699 generation of neurons
1.14 6.70e-04 GO:0016070 RNA metabolic process
1.15 6.97e-04 GO:0009966 regulation of signal transduction
1.24 7.42e-04 GO:0010629 negative regulation of gene expression
1.23 9.37e-04 GO:0032989 cellular component morphogenesis
1.23 1.00e-03 GO:0030030 cell projection organization
1.16 1.09e-03 GO:0009893 positive regulation of metabolic process
1.14 1.14e-03 GO:0023051 regulation of signaling
1.17 1.30e-03 GO:0051246 regulation of protein metabolic process
1.23 1.38e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.25 1.50e-03 GO:0000904 cell morphogenesis involved in differentiation
1.10 1.61e-03 GO:0048856 anatomical structure development
1.10 1.88e-03 GO:0019538 protein metabolic process
1.14 1.99e-03 GO:0065009 regulation of molecular function
1.16 2.37e-03 GO:0031325 positive regulation of cellular metabolic process
1.10 2.62e-03 GO:0048731 system development
1.18 3.17e-03 GO:0031324 negative regulation of cellular metabolic process
1.31 3.86e-03 GO:0060284 regulation of cell development
1.24 4.18e-03 GO:0048858 cell projection morphogenesis
1.24 4.35e-03 GO:0032990 cell part morphogenesis
1.14 4.65e-03 GO:0009653 anatomical structure morphogenesis
1.18 4.78e-03 GO:0048468 cell development
1.24 4.82e-03 GO:0031175 neuron projection development
1.22 7.25e-03 GO:0048666 neuron development
1.28 7.45e-03 GO:0051301 cell division
1.21 8.14e-03 GO:0051726 regulation of cell cycle
1.21 9.13e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.25 9.61e-03 GO:0000279 M phase
1.30 1.02e-02 GO:0048285 organelle fission
1.44 1.05e-02 GO:0008286 insulin receptor signaling pathway
1.23 1.33e-02 GO:0045892 negative regulation of transcription, DNA-dependent
1.23 1.40e-02 GO:0051338 regulation of transferase activity
1.25 1.53e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
1.16 1.79e-02 GO:0010646 regulation of cell communication
1.20 1.87e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.24 2.09e-02 GO:0048812 neuron projection morphogenesis
1.22 2.21e-02 GO:0051253 negative regulation of RNA metabolic process
1.29 2.36e-02 GO:0000087 M phase of mitotic cell cycle
1.19 2.39e-02 GO:0009890 negative regulation of biosynthetic process
1.18 2.62e-02 GO:0031399 regulation of protein modification process
1.30 2.62e-02 GO:0051960 regulation of nervous system development
1.20 3.10e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.26 3.21e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.19 3.29e-02 GO:0010628 positive regulation of gene expression
1.31 3.39e-02 GO:0050767 regulation of neurogenesis
1.08 3.39e-02 GO:0051179 localization
1.24 3.44e-02 GO:0007409 axonogenesis
1.29 3.58e-02 GO:0000280 nuclear division
1.29 3.58e-02 GO:0007067 mitosis
1.20 3.91e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
1.36 4.28e-02 GO:0032869 cellular response to insulin stimulus
1.17 4.61e-02 GO:0051128 regulation of cellular component organization
1.19 4.70e-02 GO:0051254 positive regulation of RNA metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.09 2.07e-52 GO:0005622 intracellular
1.10 2.13e-51 GO:0044424 intracellular part
1.10 5.39e-38 GO:0043229 intracellular organelle
1.10 6.37e-38 GO:0043226 organelle
1.11 2.51e-37 GO:0043227 membrane-bounded organelle
1.11 5.23e-37 GO:0043231 intracellular membrane-bounded organelle
1.11 6.29e-30 GO:0005737 cytoplasm
1.13 1.58e-22 GO:0005634 nucleus
1.12 3.20e-17 GO:0044446 intracellular organelle part
1.12 3.37e-17 GO:0044422 organelle part
1.11 9.32e-17 GO:0044444 cytoplasmic part
1.03 1.87e-13 GO:0044464 cell part
1.03 2.20e-13 GO:0005623 cell
1.18 8.72e-12 GO:0044428 nuclear part
1.18 1.38e-10 GO:0031981 nuclear lumen
1.16 1.57e-10 GO:0070013 intracellular organelle lumen
1.16 4.34e-10 GO:0043233 organelle lumen
1.17 4.39e-10 GO:0005829 cytosol
1.16 5.03e-10 GO:0031974 membrane-enclosed lumen
1.27 2.65e-08 GO:0015630 microtubule cytoskeleton
1.11 2.33e-07 GO:0032991 macromolecular complex
1.12 2.70e-07 GO:0043234 protein complex
1.18 2.14e-06 GO:0005654 nucleoplasm
1.12 4.79e-06 GO:0043228 non-membrane-bounded organelle
1.12 4.79e-06 GO:0043232 intracellular non-membrane-bounded organelle
1.14 2.48e-04 GO:0012505 endomembrane system
1.11 5.72e-04 GO:0031090 organelle membrane
1.20 7.77e-04 GO:0044451 nucleoplasm part
1.23 1.89e-03 GO:0005730 nucleolus
1.15 4.17e-03 GO:0005783 endoplasmic reticulum
1.26 5.39e-03 GO:0005815 microtubule organizing center
1.31 1.01e-02 GO:0005813 centrosome
1.34 1.27e-02 GO:0005819 spindle
1.27 1.37e-02 GO:0005874 microtubule
1.19 1.62e-02 GO:0005694 chromosome
1.47 2.23e-02 GO:0042470 melanosome
1.47 2.23e-02 GO:0048770 pigment granule
1.30 3.52e-02 GO:0000228 nuclear chromosome
1.45 3.78e-02 GO:0016585 chromatin remodeling complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.12 4.33e-29 GO:0005515 protein binding
1.06 5.70e-18 GO:0005488 binding
1.09 8.02e-10 GO:0003824 catalytic activity
1.12 2.32e-05 GO:0000166 nucleotide binding
1.10 3.11e-05 GO:0003676 nucleic acid binding
1.17 3.78e-04 GO:0030528 transcription regulator activity
1.21 7.42e-04 GO:0043565 sequence-specific DNA binding
1.11 9.09e-04 GO:0003677 DNA binding
1.12 1.04e-03 GO:0032553 ribonucleotide binding
1.12 1.04e-03 GO:0032555 purine ribonucleotide binding
1.12 1.31e-03 GO:0017076 purine nucleotide binding
1.25 1.40e-03 GO:0019904 protein domain specific binding
1.12 1.58e-03 GO:0016740 transferase activity
1.29 1.62e-03 GO:0016563 transcription activator activity
1.12 2.06e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.17 2.57e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.16 7.35e-03 GO:0001071 nucleic acid binding transcription factor activity
1.16 7.35e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.18 7.72e-03 GO:0019899 enzyme binding
1.12 1.01e-02 GO:0030554 adenyl nucleotide binding
1.12 1.03e-02 GO:0032559 adenyl ribonucleotide binding
1.12 1.76e-02 GO:0005524 ATP binding
1.26 3.94e-02 GO:0008134 transcription factor binding
1.26 4.04e-02 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.16 4.43e-02 GO:0016301 kinase activity