Motif ID: SP1.p2

Z-value: 0.917


Transcription factors associated with SP1.p2:

Gene SymbolEntrez IDGene Name
SP1 6667 Sp1 transcription factor



Activity profile for motif SP1.p2.

activity profile for motif SP1.p2


Sorted Z-values histogram for motif SP1.p2

Sorted Z-values for motif SP1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SP1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_63829616 5.000 NM_004451
ESRRA
estrogen-related receptor alpha
chr1_-_32574185 4.342 NM_023009
MARCKSL1
MARCKS-like 1
chr1_-_40903897 4.325 NM_014747
RIMS3
regulating synaptic membrane exocytosis 3
chr1_-_40903700 3.949 RIMS3
regulating synaptic membrane exocytosis 3
chr19_-_55524445 3.862 NM_004977
KCNC3
potassium voltage-gated channel, Shaw-related subfamily, member 3
chr20_+_1154763 3.374 NM_001136566
RAD21L1
RAD21-like 1 (S. pombe)
chr16_-_8870343 3.328 NM_014316
CARHSP1
calcium regulated heat stable protein 1, 24kDa
chr16_-_88295595 3.257 NM_152339
SPATA2L
spermatogenesis associated 2-like
chr20_-_3102169 3.216 ProSAPiP1
ProSAPiP1 protein
chr21_+_42946719 3.010 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A



















chr6_-_31805547 2.939 DDAH2
dimethylarginine dimethylaminohydrolase 2
chr20_-_51644187 2.891 ZNF217
zinc finger protein 217
chr17_+_77582774 2.781 NM_005052
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr2_+_46623396 2.746 RHOQ
ras homolog gene family, member Q
chr21_-_44583696 2.732 NM_004928
C21orf2
chromosome 21 open reading frame 2
chr1_+_27925054 2.677 NM_001143912
NM_001143913
NM_001143914
NM_001143915
NM_152660
FAM76A




family with sequence similarity 76, member A




chr17_+_52266451 2.647 NM_003647
DGKE
diacylglycerol kinase, epsilon 64kDa
chr6_+_7052798 2.566 NM_001168344
RREB1
ras responsive element binding protein 1
chr19_+_659766 2.553 NM_001040134
NM_002579
PALM

paralemmin

chr21_-_44583662 2.538 C21orf2
chromosome 21 open reading frame 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 113 entries
enrichment   p-value GO term description
1.44 1.05e-02 GO:0008286 insulin receptor signaling pathway
1.36 4.28e-02 GO:0032869 cellular response to insulin stimulus
1.31 3.86e-03 GO:0060284 regulation of cell development
1.31 3.39e-02 GO:0050767 regulation of neurogenesis
1.30 1.02e-02 GO:0048285 organelle fission
1.30 2.62e-02 GO:0051960 regulation of nervous system development
1.29 2.36e-02 GO:0000087 M phase of mitotic cell cycle
1.29 3.58e-02 GO:0000280 nuclear division
1.29 3.58e-02 GO:0007067 mitosis
1.28 7.45e-03 GO:0051301 cell division
1.26 3.21e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.25 2.46e-04 GO:0000278 mitotic cell cycle
1.25 1.50e-03 GO:0000904 cell morphogenesis involved in differentiation
1.25 9.61e-03 GO:0000279 M phase
1.25 1.53e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
1.24 5.07e-06 GO:0022402 cell cycle process
1.24 4.78e-05 GO:0022403 cell cycle phase
1.24 4.45e-04 GO:0000902 cell morphogenesis
1.24 7.42e-04 GO:0010629 negative regulation of gene expression
1.24 4.18e-03 GO:0048858 cell projection morphogenesis

Gene overrepresentation in compartment category:

Showing 1 to 20 of 39 entries
enrichment   p-value GO term description
1.47 2.23e-02 GO:0042470 melanosome
1.47 2.23e-02 GO:0048770 pigment granule
1.45 3.78e-02 GO:0016585 chromatin remodeling complex
1.34 1.27e-02 GO:0005819 spindle
1.31 1.01e-02 GO:0005813 centrosome
1.30 3.52e-02 GO:0000228 nuclear chromosome
1.27 2.65e-08 GO:0015630 microtubule cytoskeleton
1.27 1.37e-02 GO:0005874 microtubule
1.26 5.39e-03 GO:0005815 microtubule organizing center
1.23 1.89e-03 GO:0005730 nucleolus
1.20 7.77e-04 GO:0044451 nucleoplasm part
1.19 1.62e-02 GO:0005694 chromosome
1.18 8.72e-12 GO:0044428 nuclear part
1.18 1.38e-10 GO:0031981 nuclear lumen
1.18 2.14e-06 GO:0005654 nucleoplasm
1.17 4.39e-10 GO:0005829 cytosol
1.16 1.57e-10 GO:0070013 intracellular organelle lumen
1.16 4.34e-10 GO:0043233 organelle lumen
1.16 5.03e-10 GO:0031974 membrane-enclosed lumen
1.15 4.17e-03 GO:0005783 endoplasmic reticulum

Gene overrepresentation in function category:

Showing 1 to 20 of 25 entries
enrichment   p-value GO term description
1.29 1.62e-03 GO:0016563 transcription activator activity
1.26 3.94e-02 GO:0008134 transcription factor binding
1.26 4.04e-02 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.25 1.40e-03 GO:0019904 protein domain specific binding
1.21 7.42e-04 GO:0043565 sequence-specific DNA binding
1.18 7.72e-03 GO:0019899 enzyme binding
1.17 3.78e-04 GO:0030528 transcription regulator activity
1.17 2.57e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.16 7.35e-03 GO:0001071 nucleic acid binding transcription factor activity
1.16 7.35e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.16 4.43e-02 GO:0016301 kinase activity
1.12 4.33e-29 GO:0005515 protein binding
1.12 2.32e-05 GO:0000166 nucleotide binding
1.12 1.04e-03 GO:0032553 ribonucleotide binding
1.12 1.04e-03 GO:0032555 purine ribonucleotide binding
1.12 1.31e-03 GO:0017076 purine nucleotide binding
1.12 1.58e-03 GO:0016740 transferase activity
1.12 2.06e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.12 1.01e-02 GO:0030554 adenyl nucleotide binding
1.12 1.03e-02 GO:0032559 adenyl ribonucleotide binding