Motif ID: SPZ1.p2

Z-value: 1.170


Transcription factors associated with SPZ1.p2:

Gene SymbolEntrez IDGene Name
SPZ1 84654 spermatogenic leucine zipper 1



Activity profile for motif SPZ1.p2.

activity profile for motif SPZ1.p2


Sorted Z-values histogram for motif SPZ1.p2

Sorted Z-values for motif SPZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPZ1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_29373365 1.746 NM_001014999
NM_001015000
NM_024044
NM_178044
 SLX1A-SULT1A3
SLX1A

SLX1B

SLX1A-SULT1A3 read-through transcript
SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)

SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)

chr17_+_35075124 1.576 NM_003673
 TCAP
titin-cap (telethonin)
chr3_+_152287365 1.545 NM_053002
 MED12L
mediator complex subunit 12-like
chr10_+_123862430 1.161 TACC2
transforming, acidic coiled-coil containing protein 2
chr16_-_66535457 1.115 NM_000229
 LCAT
lecithin-cholesterol acyltransferase
chr19_+_59077241 0.896 NM_002739
 PRKCG
protein kinase C, gamma
chr17_-_40344203 0.889 GFAP
glial fibrillary acidic protein
chr4_+_184257337 0.888 NM_024949
 WWC2
WW and C2 domain containing 2
chr16_-_66535923 0.861 SLC12A4
solute carrier family 12 (potassium/chloride transporters), member 4
chr17_-_36469869 0.836 NM_001165252
 LOC730755
keratin associated protein 2-4-like
chr5_-_45731976 0.830 NM_021072
 HCN1
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr4_-_22126437 0.808 NM_145290
 GPR125
G protein-coupled receptor 125
chr4_-_158111995 0.792 NM_016205
 PDGFC
platelet derived growth factor C
chr8_-_22145795 0.792 NM_001099335
NM_014759
 PHYHIP

phytanoyl-CoA 2-hydroxylase interacting protein

chr4_-_187884721 0.788


chr5_-_176914143 0.777 NM_001190946
 FAM193B
family with sequence similarity 193, member B
chr19_+_45799060 0.761 NM_001042545
 LTBP4
latent transforming growth factor beta binding protein 4
chr5_+_139473873 0.760 NM_005859
 PURA
purine-rich element binding protein A
chr5_-_45731588 0.757 HCN1
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr22_-_22970850 0.752 NM_001099781
NM_001099782
NM_004121
 GGT5


gamma-glutamyltransferase 5



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 118 entries
enrichment   p-value GO term description
2.57 2.78e-03 GO:0032368 regulation of lipid transport
2.34 3.38e-03 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway
2.04 2.94e-03 GO:0030324 lung development
2.03 2.87e-03 GO:0030323 respiratory tube development
1.96 2.38e-03 GO:0060541 respiratory system development
1.94 1.50e-03 GO:0033673 negative regulation of kinase activity
1.91 4.49e-02 GO:0048754 branching morphogenesis of a tube
1.89 3.76e-03 GO:0001763 morphogenesis of a branching structure
1.89 8.24e-03 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
1.88 1.18e-02 GO:0006469 negative regulation of protein kinase activity
1.87 4.73e-03 GO:0051348 negative regulation of transferase activity
1.84 2.50e-03 GO:0001655 urogenital system development
1.80 5.68e-03 GO:0060562 epithelial tube morphogenesis
1.70 5.88e-05 GO:0035295 tube development
1.69 1.53e-02 GO:0035239 tube morphogenesis
1.67 2.50e-03 GO:0002009 morphogenesis of an epithelium
1.63 3.71e-04 GO:0048729 tissue morphogenesis
1.63 5.05e-04 GO:0051270 regulation of cellular component movement
1.63 2.34e-03 GO:2000145 regulation of cell motility
1.63 2.59e-03 GO:0030334 regulation of cell migration

Gene overrepresentation in compartment category:

Showing 1 to 20 of 27 entries
enrichment   p-value GO term description
1.84 4.27e-05 GO:0070161 anchoring junction
1.80 1.61e-02 GO:0030055 cell-substrate junction
1.79 6.88e-04 GO:0005912 adherens junction
1.78 3.22e-02 GO:0005924 cell-substrate adherens junction
1.64 4.52e-04 GO:0016323 basolateral plasma membrane
1.59 4.41e-02 GO:0043025 neuronal cell body
1.50 2.59e-04 GO:0043005 neuron projection
1.46 8.13e-06 GO:0030054 cell junction
1.39 2.78e-02 GO:0045202 synapse
1.27 1.57e-05 GO:0005856 cytoskeleton
1.26 2.69e-02 GO:0042995 cell projection
1.25 8.83e-03 GO:0044430 cytoskeletal part
1.24 3.05e-02 GO:0005794 Golgi apparatus
1.22 3.00e-05 GO:0005829 cytosol
1.18 2.98e-03 GO:0044459 plasma membrane part
1.15 1.93e-03 GO:0043234 protein complex
1.14 2.85e-02 GO:0043228 non-membrane-bounded organelle
1.14 2.85e-02 GO:0043232 intracellular non-membrane-bounded organelle
1.12 4.01e-02 GO:0032991 macromolecular complex
1.09 1.03e-06 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
3.20 3.26e-02 GO:0005024 transforming growth factor beta receptor activity
1.51 2.23e-02 GO:0032403 protein complex binding
1.46 4.79e-05 GO:0008092 cytoskeletal protein binding
1.39 2.45e-02 GO:0019904 protein domain specific binding
1.37 1.68e-04 GO:0019899 enzyme binding
1.34 8.35e-03 GO:0046983 protein dimerization activity
1.33 1.64e-03 GO:0016301 kinase activity
1.32 4.74e-04 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.32 4.91e-02 GO:0004672 protein kinase activity
1.31 1.16e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.31 3.26e-02 GO:0043565 sequence-specific DNA binding
1.29 2.35e-03 GO:0001071 nucleic acid binding transcription factor activity
1.29 2.35e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.17 6.20e-18 GO:0005515 protein binding
1.17 7.23e-03 GO:0000166 nucleotide binding
1.06 3.74e-06 GO:0005488 binding