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Motif ID: SREBF1,2.p2

Z-value: 1.333

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr8_-_71743973	3.049	NM_016027	LACTB2	lactamase, beta 2
chr12_-_47604930	2.679	NM_001143781	FKBP11	FK506 binding protein 11, 19 kDa
chr17_+_75851984	2.385
chr8_-_71743908	2.306		LACTB2	lactamase, beta 2
chr8_+_71744153	2.261	NM_001011720	XKR9	XK, Kell blood group complex subunit-related family, member 9
chr17_+_3486753	2.006		CTNS	cystinosis, nephropathic
chr20_+_43952997	1.963	NM_000308 NM_001127695 NM_001167594	CTSA	cathepsin A
chr20_-_43953036	1.949	NM_080749	NEURL2	neuralized homolog 2 (Drosophila)
chr14_-_93512818	1.818		ASB2	ankyrin repeat and SOCS box containing 2
chr22_+_34107087	1.750		HMOX1	heme oxygenase (decycling) 1
chr6_+_160310118	1.707	NM_000876	IGF2R	insulin-like growth factor 2 receptor
chr19_+_54149843	1.664	NM_004324 NM_138761 NM_138763 NM_138764	BAX	BCL2-associated X protein
chr22_+_34107051	1.468	NM_002133	HMOX1	heme oxygenase (decycling) 1
chr12_+_120840829	1.406	NM_001178003 NM_144668	WDR66	WD repeat domain 66
chr17_-_41018291	1.401
chr12_+_54396118	1.382		BLOC1S1	biogenesis of lysosomal organelles complex-1, subunit 1
chr3_-_20202622	1.362	NM_001012409 NM_001012410 NM_001012411 NM_001012412 NM_001012413 NM_138484	SGOL1	shugoshin-like 1 (S. pombe)
chr19_+_54149963	1.347		BAX	BCL2-associated X protein
chr16_-_66072477	1.302	NM_004691	ATP6V0D1	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr19_+_54149941	1.276		BAX	BCL2-associated X protein
chr8_+_75066117	1.252	NM_001195797 NM_015364	LY96	lymphocyte antigen 96
chr1_-_153195188	1.230	NM_020524	PBXIP1	pre-B-cell leukemia homeobox interacting protein 1
chr16_-_5023914	1.183		NAGPA	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr19_-_52709975	1.170		NAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha
chr16_-_5023934	1.166	NM_016256	NAGPA	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr17_-_33043514	1.152	NM_001163544 NM_001163545 NM_001163546 NM_001163547 NM_007247 NM_080550 NM_198882	SYNRG	synergin, gamma
chr16_-_4837266	1.142	NM_032569	GLYR1	glyoxylate reductase 1 homolog (Arabidopsis)
chrX_-_114703273	1.133
chr19_-_3936460	1.098	NM_001961	EEF2	eukaryotic translation elongation factor 2
chr1_-_153477511	1.089		GBA	glucosidase, beta, acid
chr17_+_39778016	1.086	NM_002087	GRN	granulin
chr22_-_35232979	1.084		FOXRED2	FAD-dependent oxidoreductase domain containing 2
chr12_+_54396099	1.079		BLOC1S1-RDH5 BLOC1S1	BLOC1S1-RDH5 read-through transcript biogenesis of lysosomal organelles complex-1, subunit 1
chr17_+_59933322	1.074		CCDC45	coiled-coil domain containing 45
chr6_-_109810354	1.073		CD164	CD164 molecule, sialomucin
chr19_-_52710129	1.046	NM_003827	NAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha
chr17_-_7078304	1.016		DVL2	dishevelled, dsh homolog 2 (Drosophila)
chr13_-_32757835	1.003	NM_178006	STARD13	StAR-related lipid transfer (START) domain containing 13
chr19_-_52710089	0.998		NAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha
chr19_+_7493436	0.989	NM_020533	MCOLN1	mucolipin 1
chr17_+_59933541	0.988	NM_138363	CCDC45	coiled-coil domain containing 45
chr6_-_33494042	0.979	NM_001014433 NM_001014837 NM_001014838 NM_001014840 NM_015921	CUTA	cutA divalent cation tolerance homolog (E. coli)
chr7_-_47588652	0.976		TNS3	tensin 3
chr18_+_9698322	0.965		RAB31	RAB31, member RAS oncogene family
chr16_-_5023562	0.956		NAGPA	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr6_+_151815298	0.943		C6orf211	chromosome 6 open reading frame 211
chr17_+_69781980	0.935	NM_001172810 NM_023036	DNAI2	dynein, axonemal, intermediate chain 2
chr17_-_60346042	0.920		LRRC37A3	leucine rich repeat containing 37, member A3
chr17_+_39778153	0.913		GRN	granulin
chr18_+_9698299	0.903		RAB31	RAB31, member RAS oncogene family
chr12_+_54396086	0.898	NM_001487	BLOC1S1	biogenesis of lysosomal organelles complex-1, subunit 1
chr13_-_31900218	0.892	NM_001079691 NM_052818	N4BP2L1	NEDD4 binding protein 2-like 1
chr1_+_152460381	0.889		UBAP2L	ubiquitin associated protein 2-like
chr12_+_14409875	0.889	NM_018179	ATF7IP	activating transcription factor 7 interacting protein
chr2_+_241174803	0.882	NM_023083 NM_023085	CAPN10	calpain 10
chr1_+_149437602	0.851	NM_001135636 NM_001135637 NM_001135638 NM_003557	PIP5K1A	phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
chr22_+_34025872	0.851		TOM1	target of myb1 (chicken)
chr1_-_153477673	0.851	NM_001171812 NM_000157	GBA	glucosidase, beta, acid
chr3_+_39399770	0.846	NM_017875	SLC25A38	solute carrier family 25, member 38
chr19_-_2734324	0.844		SGTA	small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr7_-_27162688	0.839	NM_006896	HOXA7	homeobox A7
chr16_+_55580910	0.833	NM_032206	NLRC5	NLR family, CARD domain containing 5
chr6_-_33493640	0.831		CUTA	cutA divalent cation tolerance homolog (E. coli)
chr19_-_42098919	0.827	NM_001037232	ZNF829	zinc finger protein 829
chr12_+_28234657	0.805
chr3_+_44878380	0.799	NM_144638	TMEM42	transmembrane protein 42
chr17_+_59933646	0.799		CCDC45	coiled-coil domain containing 45
chr10_+_23768203	0.790	NM_001145373	OTUD1	OTU domain containing 1
chr17_+_39778180	0.783		GRN	granulin
chr19_-_12747421	0.779	NM_001100176 NM_013312	HOOK2	hook homolog 2 (Drosophila)
chr9_-_21984414	0.775	NM_058195	CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chrX_-_102205736	0.775		BEX1	brain expressed, X-linked 1
chr14_-_93512647	0.774		ASB2	ankyrin repeat and SOCS box containing 2
chr22_-_35233032	0.773	NM_024955 NM_001102371	FOXRED2	FAD-dependent oxidoreductase domain containing 2
chr19_-_41236959	0.763		THAP8	THAP domain containing 8
chr16_+_5023672	0.758		LOC100507589	hypothetical LOC100507589
chr6_-_143874463	0.757	NM_032020	FUCA2	fucosidase, alpha-L- 2, plasma
chr18_+_9698187	0.756	NM_006868	RAB31	RAB31, member RAS oncogene family
chr15_-_70455355	0.748	NM_000520	HEXA	hexosaminidase A (alpha polypeptide)
chr3_-_123995216	0.747	NM_024610	HSPBAP1	HSPB (heat shock 27kDa) associated protein 1
chr18_+_9698269	0.742		RAB31	RAB31, member RAS oncogene family
chr2_+_143603439	0.714		ARHGAP15	Rho GTPase activating protein 15
chr2_+_227898163	0.713		MFF	mitochondrial fission factor
chr6_-_84994032	0.710	NM_014895	KIAA1009	KIAA1009
chr16_+_639278	0.696	NM_145294	WDR90	WD repeat domain 90
chr1_+_17121012	0.694	NM_014675	CROCC	ciliary rootlet coiled-coil, rootletin
chr17_+_39778191	0.692		GRN	granulin
chr17_-_44022595	0.687		HOXB3	homeobox B3
chr18_+_54958095	0.685	NM_033280	SEC11C	SEC11 homolog C (S. cerevisiae)
chr8_-_82186832	0.685	NM_018440	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1
chr2_-_20115269	0.684	NM_014713	LAPTM4A	lysosomal protein transmembrane 4 alpha
chr10_+_69314714	0.682		SIRT1	sirtuin 1
chr12_+_67426184	0.682	NM_018656	SLC35E3	solute carrier family 35, member E3
chr11_+_107384819	0.674		CUL5	cullin 5
chr1_-_202595666	0.666	NM_014935	PLEKHA6	pleckstrin homology domain containing, family A member 6
chr5_+_172343368	0.666	NM_003945	ATP6V0E1	ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
chr7_-_42918013	0.664	NM_001099858 NM_024054	C7orf25	chromosome 7 open reading frame 25
chr17_-_7138620	0.664		YBX2	Y box binding protein 2
chr19_-_41237138	0.662		THAP8	THAP domain containing 8
chr11_-_60475558	0.662	NM_016582	SLC15A3	solute carrier family 15, member 3
chr14_-_80757327	0.655	NM_201595	GTF2A1	general transcription factor IIA, 1, 19/37kDa
chr12_+_100198026	0.654	NM_014503	UTP20	UTP20, small subunit (SSU) processome component, homolog (yeast)
chr19_-_42098758	0.652	NM_001171979	ZNF829	zinc finger protein 829
chr19_-_15436333	0.652	NM_022904	RASAL3	RAS protein activator like 3
chr10_+_69314347	0.649	NM_012238	SIRT1	sirtuin 1
chr1_-_154532019	0.649	NM_144580	C1orf85	chromosome 1 open reading frame 85
chr1_-_153195219	0.648		PBXIP1	pre-B-cell leukemia homeobox interacting protein 1
chr10_-_93382779	0.640		PPP1R3C	protein phosphatase 1, regulatory (inhibitor) subunit 3C
chr2_+_46779553	0.640	NM_014011	SOCS5	suppressor of cytokine signaling 5
chr11_+_59979857	0.638	NM_021950 NM_152866	MS4A1	membrane-spanning 4-domains, subfamily A, member 1
chr17_+_3486510	0.636	NM_001031681 NM_004937	CTNS	cystinosis, nephropathic
chrX_+_54483565	0.636	NM_058163	TSR2	TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)
chr6_+_122762449	0.632		HSF2	heat shock transcription factor 2
chr1_-_152797820	0.632		UBE2Q1	ubiquitin-conjugating enzyme E2Q family member 1
chr10_-_45410197	0.630	NM_001002265 NM_145021	MARCH8	membrane-associated ring finger (C3HC4) 8
chr22_+_34025792	0.630	NM_001135730 NM_001135732 NM_005488	TOM1	target of myb1 (chicken)
chr17_+_35728039	0.629		RARA	retinoic acid receptor, alpha
chr19_+_42099073	0.628	NM_198539	ZNF568	zinc finger protein 568
chr4_+_177224142	0.626		WDR17	WD repeat domain 17
chr16_-_15644465	0.626	NM_001184998 NM_001184999 NM_014647	KIAA0430	KIAA0430
chr10_+_102746819	0.625	NM_032429	LZTS2	leucine zipper, putative tumor suppressor 2
chr17_+_35728070	0.620		RARA	retinoic acid receptor, alpha
chr19_-_2734332	0.619	NM_003021	SGTA	small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr19_+_55614006	0.619	NM_003121	SPIB	Spi-B transcription factor (Spi-1/PU.1 related)
chr17_-_37586716	0.617	NM_012285	KCNH4	potassium voltage-gated channel, subfamily H (eag-related), member 4
chr1_+_88922424	0.616	NM_006256	PKN2	protein kinase N2
chr20_+_56861430	0.609	NM_001077490 NM_080425	GNAS	GNAS complex locus
chr19_-_2734225	0.608		SGTA	small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr3_+_51403760	0.608	NM_013286	RBM15B	RNA binding motif protein 15B
chr12_-_107551783	0.606	NM_003006	SELPLG	selectin P ligand
chr6_-_99979850	0.606	NM_015491 NM_032870	SFRS18	splicing factor, arginine/serine-rich 18
chr5_-_150517499	0.606		ANXA6	annexin A6
chr8_-_126173055	0.605		KIAA0196	KIAA0196
chr19_-_12747263	0.601		HOOK2	hook homolog 2 (Drosophila)
chr14_-_91642703	0.601	NM_001127696 NM_001127697 NM_001164774 NM_001164776 NM_001164777 NM_001164778 NM_001164779 NM_001164780 NM_001164781 NM_001164782 NM_004993 NM_030660	ATXN3	ataxin 3
chr15_-_70455153	0.600		HEXA	hexosaminidase A (alpha polypeptide)
chr17_-_4405367	0.600	NM_001105538 NM_014520	MYBBP1A	MYB binding protein (P160) 1a
chr19_-_2734313	0.597		SGTA	small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr1_-_31618405	0.594	NM_004102	FABP3	fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr8_+_98725604	0.593		MTDH	metadherin
chr1_+_92187515	0.592	NM_207189	BRDT	bromodomain, testis-specific
chr20_+_43028533	0.591	NM_006282	STK4	serine/threonine kinase 4
chr13_+_23361591	0.588	NM_001135816	PCOTH	prostate collagen triple helix
chr4_-_47160476	0.576		COMMD8	COMM domain containing 8
chr3_+_150191884	0.574	NM_001184720 NM_001184721 NM_004130	GYG1	glycogenin 1
chr5_-_150517454	0.571		ANXA6	annexin A6
chr2_+_85834111	0.569	NM_032827	ATOH8	atonal homolog 8 (Drosophila)
chr9_+_6747636	0.567	NM_001146694 NM_001146695 NM_015061	KDM4C	lysine (K)-specific demethylase 4C
chr20_+_43028590	0.567		STK4	serine/threonine kinase 4
chr14_-_91642641	0.565		ATXN3 ATXN8	ataxin 3 ataxin 8
chr17_-_7138590	0.563	NM_015982	YBX2	Y box binding protein 2
chr17_-_40263124	0.556	NM_005497	GJC1	gap junction protein, gamma 1, 45kDa
chr18_-_19271814	0.555	NM_032933	C18orf45	chromosome 18 open reading frame 45
chr6_-_33493898	0.551		CUTA	cutA divalent cation tolerance homolog (E. coli)
chr9_-_21984379	0.551		CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr1_+_152459918	0.550	NM_014847	UBAP2L	ubiquitin associated protein 2-like
chr1_-_154532081	0.545		C1orf85	chromosome 1 open reading frame 85
chr1_-_33669190	0.540		PHC2	polyhomeotic homolog 2 (Drosophila)
chr4_-_47160403	0.539	NM_017845	COMMD8	COMM domain containing 8
chr19_-_3936343	0.538		EEF2	eukaryotic translation elongation factor 2
chr10_-_93382837	0.538	NM_005398	PPP1R3C	protein phosphatase 1, regulatory (inhibitor) subunit 3C
chr11_-_106394039	0.537	NM_000855	GUCY1A2	guanylate cyclase 1, soluble, alpha 2
chr5_+_34692124	0.535	NM_001145522 NM_015577	RAI14	retinoic acid induced 14
chr5_-_159478967	0.534	NM_001130864 NM_052927	PWWP2A	PWWP domain containing 2A
chr5_+_172343415	0.531		ATP6V0E1	ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
chr6_+_122762384	0.531	NM_001135564 NM_004506	HSF2	heat shock transcription factor 2
chr7_-_29995809	0.530	NM_001145515 NM_014766 NM_001145513	SCRN1	secernin 1
chr12_+_63132106	0.527	NM_013254	TBK1	TANK-binding kinase 1
chr18_-_27777085	0.525	NM_014939	TRAPPC8	trafficking protein particle complex 8
chrX_-_100549444	0.525		GLA	galactosidase, alpha
chr5_+_176663385	0.521		PRELID1	PRELI domain containing 1
chr6_-_33493792	0.520		CUTA	cutA divalent cation tolerance homolog (E. coli)
chr8_+_1759502	0.516	NM_014629	ARHGEF10	Rho guanine nucleotide exchange factor (GEF) 10
chrX_-_85189194	0.515	NM_000390 NM_001145414	CHM	choroideremia (Rab escort protein 1)
chr5_+_172343429	0.515		ATP6V0E1	ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
chr4_-_90197140	0.511	NM_014883	FAM13A	family with sequence similarity 13, member A
chr12_-_107551744	0.511		SELPLG	selectin P ligand
chr12_+_115660468	0.509	NM_001109903 NM_032814	RNFT2	ring finger protein, transmembrane 2
chr17_-_17081217	0.508	NM_144606 NM_144997	FLCN	folliculin
chr13_-_23361430	0.507	NM_005932	MIPEP	mitochondrial intermediate peptidase
chr8_+_98725505	0.505	NM_178812	MTDH	metadherin
chr17_+_35727998	0.504	NM_001145301 NM_001145302	RARA	retinoic acid receptor, alpha
chr10_-_81576162	0.504
chrX_-_102205752	0.504	NM_018476	BEX1	brain expressed, X-linked 1
chr1_+_234372454	0.503	NM_003272	GPR137B	G protein-coupled receptor 137B
chr7_+_882704	0.503	NM_015949	GET4	golgi to ER traffic protein 4 homolog (S. cerevisiae)
chr1_-_52936573	0.502		C1orf163	chromosome 1 open reading frame 163
chr14_-_63830830	0.500	NM_001040275 NM_001437	ESR2	estrogen receptor 2 (ER beta)
chr8_+_123863075	0.500	NM_014943	ZHX2	zinc fingers and homeoboxes 2
chr3_-_49370682	0.499		GPX1	glutathione peroxidase 1
chr9_-_21984329	0.499		CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr14_+_95575319	0.498		C14orf132	chromosome 14 open reading frame 132
chr3_-_191321367	0.498		LEPREL1	leprecan-like 1
chr8_-_54918389	0.498	NM_015941 NM_213619	ATP6V1H	ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr4_-_23500706	0.495	NM_013261	PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr5_+_89890366	0.495	NM_032119	GPR98	G protein-coupled receptor 98
chr17_-_7138535	0.494		YBX2	Y box binding protein 2
chr12_-_107551694	0.493		SELPLG	selectin P ligand
chr10_-_14090459	0.490		FRMD4A	FERM domain containing 4A
chr18_-_27777062	0.484		TRAPPC8	trafficking protein particle complex 8

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.25	4.57e-07	GO:0044237	cellular metabolic process
1.13	2.29e-06	GO:0009987	cellular process
1.36	1.77e-05	GO:0006807	nitrogen compound metabolic process
1.21	1.85e-05	GO:0008152	metabolic process
1.23	2.18e-05	GO:0044238	primary metabolic process
1.40	3.18e-05	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.35	9.10e-05	GO:0034641	cellular nitrogen compound metabolic process
1.40	3.19e-04	GO:0044249	cellular biosynthetic process
2.21	3.64e-04	GO:0071495	cellular response to endogenous stimulus
1.46	5.20e-04	GO:0010467	gene expression
1.37	7.70e-04	GO:0009058	biosynthetic process
1.47	1.01e-03	GO:0034645	cellular macromolecule biosynthetic process
1.26	1.14e-03	GO:0044260	cellular macromolecule metabolic process
2.18	1.77e-03	GO:0032870	cellular response to hormone stimulus
1.45	2.12e-03	GO:0009059	macromolecule biosynthetic process
5.64	3.29e-03	GO:0007040	lysosome organization
1.60	5.01e-03	GO:0032774	RNA biosynthetic process
1.63	5.42e-03	GO:0006351	transcription, DNA-dependent
1.37	5.51e-03	GO:0090304	nucleic acid metabolic process
5.08	1.12e-02	GO:0015682	ferric iron transport
5.08	1.12e-02	GO:0033572	transferrin transport
4.04	1.28e-02	GO:0007033	vacuole organization
2.64	1.85e-02	GO:0008286	insulin receptor signaling pathway
1.78	2.76e-02	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.15	3.21e-02	GO:0050789	regulation of biological process
2.36	3.52e-02	GO:0032869	cellular response to insulin stimulus
1.20	3.63e-02	GO:0043170	macromolecule metabolic process
6.16	4.53e-02	GO:0030641	regulation of cellular pH
1.39	4.71e-02	GO:0016070	RNA metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.17	6.05e-15	GO:0044424	intracellular part
1.16	7.34e-14	GO:0005622	intracellular
1.24	6.00e-13	GO:0005737	cytoplasm
1.21	1.89e-11	GO:0043227	membrane-bounded organelle
1.21	3.47e-11	GO:0043231	intracellular membrane-bounded organelle
1.29	1.54e-10	GO:0044444	cytoplasmic part
1.18	1.97e-10	GO:0043226	organelle
1.18	2.90e-10	GO:0043229	intracellular organelle
1.28	1.81e-08	GO:0044422	organelle part
1.28	1.97e-08	GO:0044446	intracellular organelle part
2.47	1.75e-07	GO:0005773	vacuole
3.23	1.84e-07	GO:0005774	vacuolar membrane
3.09	6.81e-07	GO:0044437	vacuolar part
1.45	8.36e-07	GO:0031974	membrane-enclosed lumen
1.44	3.59e-06	GO:0043233	organelle lumen
1.60	5.68e-06	GO:0005654	nucleoplasm
1.43	7.08e-06	GO:0070013	intracellular organelle lumen
1.44	1.49e-05	GO:0005829	cytosol
3.25	1.55e-05	GO:0005765	lysosomal membrane
1.23	4.51e-05	GO:0005634	nucleus
2.33	5.65e-05	GO:0000323	lytic vacuole
2.33	5.65e-05	GO:0005764	lysosome
1.37	7.47e-04	GO:0044428	nuclear part
1.41	7.88e-04	GO:0031981	nuclear lumen
6.23	1.81e-03	GO:0033176	proton-transporting V-type ATPase complex
1.29	2.11e-03	GO:0043234	protein complex
1.25	5.00e-03	GO:0032991	macromolecular complex
1.62	5.34e-03	GO:0044451	nucleoplasm part
3.87	1.55e-02	GO:0016469	proton-transporting two-sector ATPase complex
1.05	2.65e-02	GO:0044464	cell part
1.05	2.72e-02	GO:0005623	cell
2.49	3.90e-02	GO:0005770	late endosome

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.13	1.88e-09	GO:0005488	binding
1.23	1.52e-08	GO:0005515	protein binding
1.54	2.29e-02	GO:0003723	RNA binding