Motif ID: STAT5{A,B}.p2

Z-value: 1.296


Transcription factors associated with STAT5{A,B}.p2:

Gene SymbolEntrez IDGene Name
STAT5A 6776 signal transducer and activator of transcription 5A
STAT5B 6777 signal transducer and activator of transcription 5B



Activity profile for motif STAT5{A,B}.p2.

activity profile for motif STAT5{A,B}.p2


Sorted Z-values histogram for motif STAT5{A,B}.p2

Sorted Z-values for motif STAT5{A,B}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT5{A,B}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_82674546 2.826 CCDC90B
coiled-coil domain containing 90B
chr11_-_82675024 1.949 NM_021825
 CCDC90B
coiled-coil domain containing 90B
chr19_-_49309102 1.557 LOC100379224
hypothetical LOC100379224
chr19_+_49248003 1.431 NM_013361
 ZNF223
zinc finger protein 223
chr19_+_49309350 1.390 NM_013362
 ZNF225
zinc finger protein 225
chr19_+_49361054 1.260 NM_001146220
NM_001032373
NM_001032374
NM_015919
NM_001032372
 ZNF226




zinc finger protein 226




chr19_-_62680703 1.259 NM_001024596
NM_001144068
 ZNF772

zinc finger protein 772

chr19_+_49180171 1.023 NM_003445
NM_198089
 ZNF155

zinc finger protein 155

chr9_+_129226473 0.960 NM_007135
 ZNF79
zinc finger protein 79
chr9_+_129226535 0.949 ZNF79
zinc finger protein 79
chr17_+_36515166 0.924 NM_001146041
 KRTAP4-9
keratin associated protein 4-9
chr19_+_49290319 0.894 NM_013398
 ZNF224
zinc finger protein 224
chr4_+_86615275 0.880 NM_001025616
 ARHGAP24
Rho GTPase activating protein 24
chr7_+_89870707 0.878 CLDN12
claudin 12
chr19_+_49147219 0.869 NM_013359
 ZNF221
zinc finger protein 221
chr19_-_49552638 0.846 NM_001083335
NM_013380
 ZFP112

zinc finger protein 112 homolog (mouse)

chr1_+_40769877 0.821 ZNF684
zinc finger protein 684
chr9_+_135994734 0.789 NM_052821
 WDR5
WD repeat domain 5
chr9_-_133945064 0.766 NM_004269
 CRSP8P
MED27
mediator complex subunit 27 pseudogene
mediator complex subunit 27
chr9_-_129226312 0.757



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
1.81 1.25e-03 GO:0006355 regulation of transcription, DNA-dependent
1.74 4.60e-03 GO:0051252 regulation of RNA metabolic process
1.71 5.48e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.66 1.01e-02 GO:0010468 regulation of gene expression
1.66 1.34e-02 GO:0010556 regulation of macromolecule biosynthetic process
1.63 1.01e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.61 2.33e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.61 2.33e-02 GO:0031326 regulation of cellular biosynthetic process
1.59 3.38e-02 GO:0009889 regulation of biosynthetic process
1.56 4.79e-03 GO:0080090 regulation of primary metabolic process
1.55 1.13e-02 GO:0060255 regulation of macromolecule metabolic process
1.54 8.54e-03 GO:0031323 regulation of cellular metabolic process
1.47 2.86e-02 GO:0019222 regulation of metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.52 4.10e-07 GO:0005634 nucleus
1.34 6.85e-07 GO:0043231 intracellular membrane-bounded organelle
1.34 7.67e-07 GO:0043227 membrane-bounded organelle
1.31 1.31e-07 GO:0043229 intracellular organelle
1.31 1.62e-07 GO:0043226 organelle
1.21 7.06e-05 GO:0044424 intracellular part
1.20 1.08e-04 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
2.07 1.77e-07 GO:0008270 zinc ion binding
1.97 3.25e-07 GO:0003677 DNA binding
1.92 1.88e-06 GO:0046914 transition metal ion binding
1.63 1.16e-04 GO:0003676 nucleic acid binding
1.54 3.24e-04 GO:0046872 metal ion binding
1.52 5.54e-04 GO:0043169 cation binding
1.51 6.22e-04 GO:0043167 ion binding