Motif ID: TBP.p2

Z-value: 1.827


Transcription factors associated with TBP.p2:

Gene SymbolEntrez IDGene Name
TBP 6908 TATA box binding protein



Activity profile for motif TBP.p2.

activity profile for motif TBP.p2


Sorted Z-values histogram for motif TBP.p2

Sorted Z-values for motif TBP.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TBP.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_51585004 2.165 NM_002273
 KRT8
keratin 8
chr1_+_151596953 1.522 NM_002965
 S100A9
S100 calcium binding protein A9
chr4_+_74953971 1.497 NM_001511
 CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr1_-_151296611 1.135 NM_005988
 SPRR2A
small proline-rich protein 2A
chr19_-_12773591 1.066 NM_005809
NM_181738
 PRDX2

peroxiredoxin 2

chr17_-_37034288 1.045 NM_000422
 KRT17
keratin 17
chr7_-_526005 0.952 NM_002607
NM_033023
 PDGFA

platelet-derived growth factor alpha polypeptide

chr1_-_41100589 0.911 NM_133467
 CITED4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr1_+_151270301 0.906 NM_003125
 SPRR1B
small proline-rich protein 1B
chr21_+_44729875 0.894


chr12_-_123965099 0.888 UBC
ubiquitin C
chr17_+_24598000 0.881 NM_005208
 CRYBA1
crystallin, beta A1
chr11_-_2907169 0.875 NM_003311
 PHLDA2
pleckstrin homology-like domain, family A, member 2
chr4_-_75183700 0.868 CXCL2
chemokine (C-X-C motif) ligand 2
chr11_-_6418705 0.862 NM_000613
 HPX
hemopexin
chr15_-_61461127 0.854 NM_001218
NM_206925
 CA12

carbonic anhydrase XII

chrX_-_103386215 0.842 NM_153448
 ESX1
ESX homeobox 1
chr1_+_12774132 0.781 NM_023013
 PRAMEF1
PRAME family member 1
chr1_-_154941861 0.776 NM_001878
 CRABP2
cellular retinoic acid binding protein 2
chr21_-_44795769 0.772 NM_198693
 KRTAP10-2
keratin associated protein 10-2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 65 entries
enrichment   p-value GO term description
16.37 7.89e-03 GO:0045109 intermediate filament organization
14.73 1.53e-02 GO:0046689 response to mercury ion
14.73 1.53e-02 GO:0048246 macrophage chemotaxis
12.13 1.09e-03 GO:0045104 intermediate filament cytoskeleton organization
11.78 2.16e-04 GO:0045103 intermediate filament-based process
11.57 1.08e-06 GO:0070301 cellular response to hydrogen peroxide
11.46 1.73e-03 GO:0042744 hydrogen peroxide catabolic process
9.82 1.12e-03 GO:0042743 hydrogen peroxide metabolic process
9.12 9.24e-07 GO:0031424 keratinization
8.42 1.21e-05 GO:0034614 cellular response to reactive oxygen species
7.60 4.05e-12 GO:0006334 nucleosome assembly
7.44 4.90e-13 GO:0034728 nucleosome organization
7.22 1.46e-11 GO:0031497 chromatin assembly
6.87 1.20e-05 GO:0034599 cellular response to oxidative stress
6.63 8.67e-03 GO:0072593 reactive oxygen species metabolic process
6.61 1.21e-10 GO:0065004 protein-DNA complex assembly
6.52 5.07e-11 GO:0071824 protein-DNA complex subunit organization
6.35 3.64e-05 GO:0042542 response to hydrogen peroxide
6.00 2.20e-03 GO:0051591 response to cAMP
5.98 2.44e-04 GO:0030216 keratinocyte differentiation

Gene overrepresentation in compartment category:

Showing 1 to 18 of 18 entries
enrichment   p-value GO term description
13.62 2.58e-31 GO:0045095 keratin filament
12.27 5.93e-03 GO:0005833 hemoglobin complex
10.93 2.29e-16 GO:0000786 nucleosome
10.23 2.51e-41 GO:0005882 intermediate filament
8.85 2.83e-37 GO:0045111 intermediate filament cytoskeleton
8.42 1.06e-02 GO:0001533 cornified envelope
6.99 1.47e-11 GO:0032993 protein-DNA complex
3.44 2.01e-23 GO:0005615 extracellular space
3.29 1.42e-05 GO:0000785 chromatin
3.05 4.82e-23 GO:0044421 extracellular region part
2.46 5.16e-13 GO:0044430 cytoskeletal part
2.34 8.26e-24 GO:0005576 extracellular region
2.20 4.14e-02 GO:0005625 soluble fraction
2.12 4.10e-02 GO:0031012 extracellular matrix
2.01 4.15e-10 GO:0005856 cytoskeleton
1.67 2.18e-09 GO:0043228 non-membrane-bounded organelle
1.67 2.18e-09 GO:0043232 intracellular non-membrane-bounded organelle
1.45 5.10e-06 GO:0032991 macromolecular complex

Gene overrepresentation in function category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
13.60 6.31e-04 GO:0005344 oxygen transporter activity
9.61 3.53e-09 GO:0008009 chemokine activity
8.66 1.89e-08 GO:0042379 chemokine receptor binding
6.84 3.55e-11 GO:0005179 hormone activity
6.07 3.62e-02 GO:0004601 peroxidase activity
6.07 3.62e-02 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor
5.39 1.72e-04 GO:0005200 structural constituent of cytoskeleton
4.59 2.01e-10 GO:0005125 cytokine activity
4.30 3.01e-08 GO:0005126 cytokine receptor binding
3.60 8.86e-05 GO:0001664 G-protein-coupled receptor binding
3.59 4.65e-03 GO:0020037 heme binding
3.46 1.62e-17 GO:0005198 structural molecule activity
3.37 9.93e-03 GO:0046906 tetrapyrrole binding
3.34 1.89e-03 GO:0008083 growth factor activity
2.98 2.00e-03 GO:0005506 iron ion binding
2.39 3.83e-11 GO:0005102 receptor binding
2.16 3.43e-02 GO:0030246 carbohydrate binding