Motif ID: TFDP1.p2

Z-value: 2.477

Transcription factors associated with TFDP1.p2:

Gene SymbolEntrez IDGene Name
TFDP1 7027 transcription factor Dp-1

Activity profile for motif TFDP1.p2.

activity profile for motif TFDP1.p2

Sorted Z-values histogram for motif TFDP1.p2

Sorted Z-values for motif TFDP1.p2

Network of associatons between targets according to the STRING database.

First level regulatory network of TFDP1.p2

PNG image of the network

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Top targets:

Promoter Score Refseq Gene Symbol Gene Name
chr4_-_83569853 3.146 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr6_-_107542328 2.617 NM_001080450
BEN domain containing 3
chr3_+_58452560 2.402 NM_001128214
potassium channel tetramerisation domain containing 6
chr10_-_126839546 2.249 NM_001083914
C-terminal binding protein 2
chr12_+_50271283 2.245 NM_014191
sodium channel, voltage gated, type VIII, alpha subunit
chr7_+_98084531 2.223 NM_002523
neuronal pentraxin II
chr11_-_2863536 2.178 NM_000076

cyclin-dependent kinase inhibitor 1C (p57, Kip2)

chr2_+_23461802 2.151 NM_052920
kelch-like 29 (Drosophila)
chr4_-_78959532 1.843 NM_144571
CCR4-NOT transcription complex, subunit 6-like
chr11_+_66643311 1.810 NM_012308
lysine (K)-specific demethylase 2A
chr4_-_83569572 1.706 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr10_-_128884411 1.702 NM_001039762
family with sequence similarity 196, member A
chr9_+_136673534 1.695 COL5A1
collagen, type V, alpha 1
chr10_+_23768203 1.692 NM_001145373
OTU domain containing 1
chr18_-_44189625 1.645 ZBTB7C
zinc finger and BTB domain containing 7C
chr15_+_66658626 1.634 NM_006091
coronin, actin binding protein, 2B
chr16_-_342399 1.633 NM_003502

axin 1

chr1_-_32176562 1.630 NM_080391
protein tyrosine phosphatase type IVA, member 2
chr1_+_6767968 1.601 NM_001195563

calmodulin binding transcription activator 1

chr13_-_109236897 1.598 NM_003749
insulin receptor substrate 2
chr14_-_104706159 1.585 NM_002226

jagged 2

chr10_+_129595289 1.549 NM_006504
protein tyrosine phosphatase, receptor type, E
chr7_+_3307445 1.541 NM_152744
sidekick homolog 1, cell adhesion molecule (chicken)
chr16_+_51722285 1.531 CHD9
chromodomain helicase DNA binding protein 9
chr17_-_41626032 1.529 NM_015443
chr6_-_112301123 1.527 NM_002037
FYN oncogene related to SRC, FGR, YES
chr4_-_83569476 1.518 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr11_+_74629597 1.507 NM_001195528
hypothetical LOC441617
chr17_-_41625921 1.494 NM_001193466
chr19_-_14062230 1.490 NM_138352
sterile alpha motif domain containing 1
chr17_-_39652391 1.487 UBTF
upstream binding transcription factor, RNA polymerase I
chr22_-_30072329 1.462 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr8_+_143805595 1.461 NM_016647
chromosome 8 open reading frame 55
chr3_+_195688974 1.457 FLJ34208
hypothetical LOC401106
chr4_-_39655944 1.445 NM_001100399

PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)

chr9_+_99785465 1.443 ANP32B
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr4_-_83570318 1.442 NM_031372
heterogeneous nuclear ribonucleoprotein D-like
chr9_+_128662756 1.438 NM_001099270
zinc finger and BTB domain containing 34
chr4_+_7095996 1.420 TADA2B
transcriptional adaptor 2B
chr8_+_1937711 1.396 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr22_+_39677319 1.388 RBX1
ring-box 1, E3 ubiquitin protein ligase
chr1_+_26895108 1.386 NM_006015

AT rich interactive domain 1A (SWI-like)

chr4_-_122063118 1.378 NM_018699
PR domain containing 5
chr22_+_47350781 1.372 NM_015381
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr10_+_83625049 1.365 NM_001010848

neuregulin 3

chr1_-_37752925 1.361 NM_022756
MYST/Esa1-associated factor 6
chr14_-_104705753 1.350 JAG2
jagged 2
chr4_-_39655554 1.348 PDS5A
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr19_-_52426055 1.341 NM_014417
BCL2 binding component 3
chr2_+_207016525 1.316 NM_003812
ADAM metallopeptidase domain 23
chr17_+_17525571 1.316

chr8_-_93184629 1.307 NM_001198633

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

chr15_+_73281288 1.289 C15orf39
chromosome 15 open reading frame 39
chr16_-_46976649 1.287 NM_003031
seven in absentia homolog 1 (Drosophila)
chr16_+_53522611 1.287 NM_005853
iroquois homeobox 5
chr12_-_48387233 1.278

chr1_-_32176275 1.266 PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr4_+_7096123 1.259 TADA2B
transcriptional adaptor 2B
chr4_+_145786622 1.256 NM_022475
hedgehog interacting protein
chr15_+_73281249 1.248 NM_015492
chromosome 15 open reading frame 39
chr17_-_39652449 1.245 NM_001076684
upstream binding transcription factor, RNA polymerase I
chr15_+_73281286 1.244 C15orf39
chromosome 15 open reading frame 39
chr17_+_27838041 1.242 NM_003885
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr7_-_525556 1.240 PDGFA
platelet-derived growth factor alpha polypeptide
chr5_-_136862317 1.229 SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr18_-_12874140 1.209 NM_002828

protein tyrosine phosphatase, non-receptor type 2

chr4_+_39734902 1.205 NM_018177
NEDD4 binding protein 2
chr1_-_32176475 1.205 PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr17_+_17525497 1.204 NM_030665
retinoic acid induced 1
chr13_-_25523164 1.201 NM_001007538
shisa homolog 2 (Xenopus laevis)
chr6_-_91063181 1.198 NM_021813
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr22_+_39677274 1.197 NM_014248
ring-box 1, E3 ubiquitin protein ligase
chr1_-_42274160 1.185

chr10_-_32676140 1.177 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr15_-_80125514 1.166 MEX3B
mex-3 homolog B (C. elegans)
chr8_-_11096257 1.158 NM_173683
XK, Kell blood group complex subunit-related family, member 6
chr14_+_64949192 1.148 NM_004480

fucosyltransferase 8 (alpha (1,6) fucosyltransferase)

chr22_-_30072217 1.143 NM_014323

POZ (BTB) and AT hook containing zinc finger 1

chr12_-_108802561 1.141 NM_016433
glycolipid transfer protein
chr17_-_59131210 1.137 NM_030576
LIM domain containing 2
chr5_-_140978751 1.136 NM_001079812

diaphanous homolog 1 (Drosophila)

chr8_+_38763911 1.131 TACC1
transforming, acidic coiled-coil containing protein 1
chr5_+_170779664 1.124 FGF18
fibroblast growth factor 18
chr5_-_177950161 1.116 NM_173465
collagen, type XXIII, alpha 1
chr16_+_66153810 1.112 NM_001191022

CCCTC-binding factor (zinc finger protein)

chr14_+_105028614 1.109 NM_001134875

chromosome 14 open reading frame 80

chr12_+_6907646 1.108 NM_001940
atrophin 1
chr19_+_39664706 1.099 NM_001080436
Wilms tumor 1 interacting protein
chr11_+_65594361 1.091 NM_018026
phosphofurin acidic cluster sorting protein 1
chr15_-_80125403 1.090 NM_032246
mex-3 homolog B (C. elegans)
chr15_-_42274760 1.087 FRMD5
FERM domain containing 5
chr15_+_97009194 1.082 IGF1R
insulin-like growth factor 1 receptor
chr10_+_129595349 1.073 PTPRE
protein tyrosine phosphatase, receptor type, E
chr11_+_2422747 1.065 NM_000218
potassium voltage-gated channel, KQT-like subfamily, member 1
chr19_-_45888259 1.061 NM_004756
numb homolog (Drosophila)-like
chr11_-_44928803 1.054 NM_001076787

tumor protein p53 inducible protein 11

chr3_+_49482474 1.049 NM_001165928

dystroglycan 1 (dystrophin-associated glycoprotein 1)

chr13_-_100125028 1.047 TMTC4
transmembrane and tetratricopeptide repeat containing 4
chr10_+_29006530 1.045 BAMBI
BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)
chr14_-_64948998 1.044 LOC645431
hypothetical LOC645431
chr12_+_120944174 1.041 NM_001024808

B-cell CLL/lymphoma 7A

chr17_+_45008473 1.041 NXPH3
neurexophilin 3
chr16_+_85158357 1.039 NM_005251
forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr9_+_133259330 1.035 PRRC2B
proline-rich coiled-coil 2B
chr9_+_115678365 1.032 NM_133374
zinc finger protein 618
chr1_+_9571518 1.030 NM_001010866

transmembrane protein 201

chr2_-_225615556 1.024 NM_014689
dedicator of cytokinesis 10
chr18_+_12298242 1.019 NM_032525
tubulin, beta 6
chr13_+_97593411 1.016 NM_001001715

FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)

chr12_-_6995988 1.015 NM_005768
lysophosphatidylcholine acyltransferase 3
chr5_-_140978747 1.014 DIAPH1
diaphanous homolog 1 (Drosophila)
chr17_+_52026058 1.014 NM_005450
chr4_+_38341982 1.012 NM_016531
Kruppel-like factor 3 (basic)
chr2_+_112749617 1.009 NM_198581
zinc finger CCCH-type containing 6
chr12_-_48387394 1.005 FMNL3
formin-like 3
chr10_-_32676090 1.004 NM_025209
enhancer of polycomb homolog 1 (Drosophila)
chr1_-_39814659 0.997 PABPC4
poly(A) binding protein, cytoplasmic 4 (inducible form)
chr15_-_99609197 0.992 CHSY1
chondroitin sulfate synthase 1
chr1_-_38285033 0.991 NM_002699
POU class 3 homeobox 1
chr14_+_64949447 0.988 FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr5_-_142763481 0.984 NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr15_-_42274529 0.980 NM_032892
FERM domain containing 5
chr20_-_4752067 0.976 NM_014737
Ras association (RalGDS/AF-6) domain family member 2
chr1_-_1525309 0.975 LOC643988
hypothetical LOC643988
chr19_-_7896974 0.972 NM_206833
cortexin 1
chr11_-_109672401 0.970 NM_002906
chr22_-_30071761 0.968 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr9_-_139316523 0.967 NM_001004354
NOTCH-regulated ankyrin repeat protein
chr4_-_57671273 0.967 NM_001553
insulin-like growth factor binding protein 7
chr8_+_99508425 0.964 NM_020697
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2
chr17_-_2250967 0.960 NM_020310
MAX binding protein
chr9_-_100598315 0.957 NM_173551
ankyrin repeat and sterile alpha motif domain containing 6
chr12_+_62523648 0.947

chr7_+_6596183 0.945 NM_024067
chromosome 7 open reading frame 26
chr11_+_57191887 0.942 ZDHHC5
zinc finger, DHHC-type containing 5
chr10_-_102978678 0.932 NM_006562
ladybird homeobox 1
chr11_-_110088330 0.931 NM_020809
Rho GTPase activating protein 20
chr10_+_122206455 0.923 NM_001030059
phosphatidic acid phosphatase type 2 domain containing 1A
chr15_-_62125562 0.922 NM_014326
death-associated protein kinase 2
chr7_-_5535726 0.916 ACTB
actin, beta
chr1_+_156229934 0.912 KIRREL
kin of IRRE like (Drosophila)
chr3_-_64648370 0.911 NM_182920
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr12_-_122322117 0.911 NM_004642
cyclin-dependent kinase 2 associated protein 1
chr5_-_142763393 0.910 NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr4_+_89147821 0.907 NM_000297
polycystic kidney disease 2 (autosomal dominant)
chr9_+_99785493 0.907 ANP32B
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr18_+_19848347 0.906 NM_001135993
tetratricopeptide repeat domain 39C
chr17_-_45562112 0.903 NM_174920
sterile alpha motif domain containing 14
chr2_-_174537021 0.901 NM_001017371
Sp3 transcription factor
chr9_+_99785277 0.901 NM_006401
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr5_-_140978664 0.896 DIAPH1
diaphanous homolog 1 (Drosophila)
chr12_+_44409762 0.891 NM_152641
AT rich interactive domain 2 (ARID, RFX-like)
chr7_-_526005 0.889 NM_002607

platelet-derived growth factor alpha polypeptide

chr4_-_122213018 0.887 NM_024574
chromosome 4 open reading frame 31
chr22_-_30071565 0.885 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr22_-_27405708 0.883 NM_001145418
tetratricopeptide repeat domain 28
chr19_+_10392128 0.880 NM_001111307
phosphodiesterase 4A, cAMP-specific
chr7_+_72720093 0.880 NM_001077621
vacuolar protein sorting 37 homolog D (S. cerevisiae)
chr9_+_81377419 0.879 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr2_-_183611470 0.878 NM_013436

NCK-associated protein 1

chr7_+_33911636 0.877 NM_133468
BMP binding endothelial regulator
chr7_-_27206249 0.876 NM_000522
homeobox A13
chr18_-_21186107 0.874 NM_015461
zinc finger protein 521
chr5_-_140978744 0.872 DIAPH1
diaphanous homolog 1 (Drosophila)
chr4_+_3738093 0.868 NM_000683
adrenergic, alpha-2C-, receptor
chr10_+_134201262 0.866 NM_005539
inositol polyphosphate-5-phosphatase, 40kDa
chr8_+_38763878 0.866 NM_001122824

transforming, acidic coiled-coil containing protein 1

chr4_-_25473528 0.865 NM_015187
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr8_+_60194328 0.865

chr19_-_60587414 0.864 NM_001190764
hypothetical protein LOC388564
chr21_+_41461924 0.861 BACE2
beta-site APP-cleaving enzyme 2
chr11_-_47531179 0.856 CELF1
CUGBP, Elav-like family member 1
chr11_-_64247230 0.855 NM_015080

neurexin 2

chr11_+_46256161 0.855 CREB3L1
cAMP responsive element binding protein 3-like 1
chr7_-_42243318 0.855 GLI3
GLI family zinc finger 3
chr13_-_39075355 0.852 NM_005780
lipoma HMGIC fusion partner
chr3_-_129023850 0.851 NM_007283
monoglyceride lipase
chrX_+_37315740 0.851 NM_001170331

LanC lantibiotic synthetase component C-like 3 (bacterial)

chr1_-_242681742 0.850 ADSS
adenylosuccinate synthase
chr4_-_57671307 0.848 IGFBP7
insulin-like growth factor binding protein 7
chr4_+_3264509 0.847 RGS12
regulator of G-protein signaling 12
chr1_-_39815106 0.843 NM_001135653

poly(A) binding protein, cytoplasmic 4 (inducible form)

chr2_-_175255717 0.838 NM_001077269
WAS/WASL interacting protein family, member 1
chr19_+_16083706 0.835 RAB8A
RAB8A, member RAS oncogene family
chr16_-_67977041 0.834 TERF2
telomeric repeat binding factor 2
chr6_-_85530617 0.834 NM_001080508
T-box 18
chr9_+_128416542 0.831 NM_001174146

LIM homeobox transcription factor 1, beta

chr9_-_16860719 0.830 NM_017637
basonuclin 2
chr16_+_22733307 0.830 NM_006043
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr6_+_45497796 0.829 NM_004348
runt-related transcription factor 2
chr19_+_1200882 0.828 MIDN
chr13_+_32058537 0.825 NM_015032
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr5_-_171643247 0.821 UBTD2
ubiquitin domain containing 2
chr16_-_31390926 0.820

chr5_+_127447306 0.818 NM_001046
solute carrier family 12 (sodium/potassium/chloride transporters), member 2
chr19_+_16083549 0.817 RAB8A
RAB8A, member RAS oncogene family
chr13_+_32488477 0.816 NM_004795
chr4_+_7096043 0.812 NM_152293
transcriptional adaptor 2B
chr10_+_105027431 0.811 INA
internexin neuronal intermediate filament protein, alpha
chr16_-_67977334 0.810 NM_005652
telomeric repeat binding factor 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.10 8.19e-33 GO:0009987 cellular process
1.23 8.96e-29 GO:0044260 cellular macromolecule metabolic process
1.17 1.06e-25 GO:0044237 cellular metabolic process
1.18 1.28e-21 GO:0043170 macromolecule metabolic process
1.14 1.14e-20 GO:0050794 regulation of cellular process
1.13 9.36e-19 GO:0008152 metabolic process
1.14 1.89e-18 GO:0044238 primary metabolic process
1.22 5.86e-18 GO:0016043 cellular component organization
1.24 1.87e-17 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.21 1.97e-17 GO:0071840 cellular component organization or biogenesis
1.24 3.18e-17 GO:0071841 cellular component organization or biogenesis at cellular level
1.25 3.57e-17 GO:0071842 cellular component organization at cellular level
1.12 4.23e-17 GO:0050789 regulation of biological process
1.11 2.47e-16 GO:0065007 biological regulation
1.26 2.60e-15 GO:0090304 nucleic acid metabolic process
1.28 8.54e-14 GO:0006464 protein modification process
1.20 1.19e-13 GO:0034641 cellular nitrogen compound metabolic process
1.19 2.07e-13 GO:0006807 nitrogen compound metabolic process
1.26 5.03e-13 GO:0043412 macromolecule modification
1.22 7.99e-13 GO:0044267 cellular protein metabolic process
1.27 8.91e-12 GO:0034645 cellular macromolecule biosynthetic process
1.22 2.12e-11 GO:0048522 positive regulation of cellular process
1.23 2.62e-11 GO:0048523 negative regulation of cellular process
1.26 3.43e-11 GO:0009059 macromolecule biosynthetic process
1.27 3.61e-11 GO:0023051 regulation of signaling
1.27 4.29e-11 GO:0006996 organelle organization
1.20 5.88e-11 GO:0048518 positive regulation of biological process
1.17 1.05e-10 GO:0031323 regulation of cellular metabolic process
1.28 1.24e-10 GO:0009966 regulation of signal transduction
1.35 3.61e-10 GO:0022008 neurogenesis
1.36 5.26e-10 GO:0048699 generation of neurons
1.21 6.00e-10 GO:0048519 negative regulation of biological process
1.25 6.70e-10 GO:0016070 RNA metabolic process
1.27 1.34e-09 GO:0007399 nervous system development
1.17 2.11e-09 GO:0060255 regulation of macromolecule metabolic process
1.16 2.55e-09 GO:0080090 regulation of primary metabolic process
1.15 1.99e-08 GO:0032502 developmental process
1.18 3.41e-08 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.14 5.72e-08 GO:0019222 regulation of metabolic process
1.22 7.62e-08 GO:0010467 gene expression
1.19 9.38e-08 GO:0044249 cellular biosynthetic process
1.15 9.84e-08 GO:0007275 multicellular organismal development
1.32 1.35e-07 GO:0006351 transcription, DNA-dependent
1.18 2.06e-07 GO:0010468 regulation of gene expression
1.17 2.15e-07 GO:0048731 system development
1.18 2.24e-07 GO:0009058 biosynthetic process
1.17 2.51e-07 GO:0051171 regulation of nitrogen compound metabolic process
1.16 2.63e-07 GO:0019538 protein metabolic process
1.30 2.97e-07 GO:0032774 RNA biosynthetic process
1.30 2.97e-07 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.18 3.06e-07 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.19 3.71e-07 GO:0051252 regulation of RNA metabolic process
1.55 8.73e-07 GO:0032446 protein modification by small protein conjugation
1.16 1.69e-06 GO:0031326 regulation of cellular biosynthetic process
1.15 1.70e-06 GO:0048856 anatomical structure development
1.34 1.82e-06 GO:0030182 neuron differentiation
1.16 2.34e-06 GO:0009889 regulation of biosynthetic process
1.35 3.86e-06 GO:0051726 regulation of cell cycle
1.22 4.94e-06 GO:0009653 anatomical structure morphogenesis
1.18 5.90e-06 GO:0048869 cellular developmental process
1.30 7.15e-06 GO:0033554 cellular response to stress
1.47 7.73e-06 GO:0070647 protein modification by small protein conjugation or removal
1.30 8.55e-06 GO:0051128 regulation of cellular component organization
1.18 8.63e-06 GO:0030154 cell differentiation
1.53 9.68e-06 GO:0016567 protein ubiquitination
1.16 1.05e-05 GO:0010556 regulation of macromolecule biosynthetic process
1.33 1.64e-05 GO:0007167 enzyme linked receptor protein signaling pathway
1.22 1.73e-05 GO:0035556 intracellular signal transduction
1.23 3.40e-05 GO:0051641 cellular localization
1.55 4.07e-05 GO:0048011 nerve growth factor receptor signaling pathway
1.25 4.54e-05 GO:0007049 cell cycle
1.17 4.95e-05 GO:0006355 regulation of transcription, DNA-dependent
1.36 7.32e-05 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.24 1.03e-04 GO:0008104 protein localization
1.31 1.41e-04 GO:0030030 cell projection organization
1.26 1.78e-04 GO:0048468 cell development
1.31 1.82e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.32 1.90e-04 GO:0000902 cell morphogenesis
1.39 2.09e-04 GO:0009968 negative regulation of signal transduction
1.23 2.67e-04 GO:0022607 cellular component assembly
1.22 3.39e-04 GO:0044248 cellular catabolic process
1.31 3.57e-04 GO:0051276 chromosome organization
1.31 3.84e-04 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.34 4.03e-04 GO:0031175 neuron projection development
1.29 4.13e-04 GO:0009890 negative regulation of biosynthetic process
1.21 4.30e-04 GO:0033036 macromolecule localization
1.29 4.48e-04 GO:0051254 positive regulation of RNA metabolic process
1.31 4.52e-04 GO:0006259 DNA metabolic process
1.24 4.54e-04 GO:0006793 phosphorus metabolic process
1.24 4.54e-04 GO:0006796 phosphate metabolic process
1.22 4.96e-04 GO:0044085 cellular component biogenesis
1.30 5.24e-04 GO:0032989 cellular component morphogenesis
1.39 5.46e-04 GO:0051056 regulation of small GTPase mediated signal transduction
1.27 6.46e-04 GO:0046907 intracellular transport
1.42 6.92e-04 GO:0060284 regulation of cell development
1.34 6.95e-04 GO:0000904 cell morphogenesis involved in differentiation
1.27 7.35e-04 GO:0016192 vesicle-mediated transport
1.45 7.42e-04 GO:0035295 tube development
1.31 7.92e-04 GO:0000278 mitotic cell cycle
1.27 7.97e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.26 9.12e-04 GO:0051173 positive regulation of nitrogen compound metabolic process
1.29 9.19e-04 GO:0010558 negative regulation of macromolecule biosynthetic process
1.28 9.20e-04 GO:0031327 negative regulation of cellular biosynthetic process
1.31 1.03e-03 GO:0048666 neuron development
1.60 1.29e-03 GO:0016311 dephosphorylation
1.31 1.31e-03 GO:0051253 negative regulation of RNA metabolic process
1.33 1.32e-03 GO:0032990 cell part morphogenesis
1.29 1.43e-03 GO:0009057 macromolecule catabolic process
1.29 1.43e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.32 1.58e-03 GO:0048858 cell projection morphogenesis
1.24 1.90e-03 GO:0010605 negative regulation of macromolecule metabolic process
1.31 2.07e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.26 2.17e-03 GO:0071844 cellular component assembly at cellular level
1.34 2.36e-03 GO:0010648 negative regulation of cell communication
1.20 2.69e-03 GO:0009893 positive regulation of metabolic process
1.34 2.92e-03 GO:0048812 neuron projection morphogenesis
1.11 2.95e-03 GO:0023052 signaling
1.21 3.04e-03 GO:0010646 regulation of cell communication
1.39 3.11e-03 GO:0007411 axon guidance
1.34 3.21e-03 GO:0023057 negative regulation of signaling
1.21 3.23e-03 GO:0051649 establishment of localization in cell
1.22 3.34e-03 GO:0032268 regulation of cellular protein metabolic process
1.61 3.40e-03 GO:0006470 protein dephosphorylation
1.20 3.46e-03 GO:0031325 positive regulation of cellular metabolic process
1.34 3.60e-03 GO:0007409 axonogenesis
1.31 3.64e-03 GO:0044265 cellular macromolecule catabolic process
1.23 4.12e-03 GO:0031324 negative regulation of cellular metabolic process
1.28 4.17e-03 GO:0010629 negative regulation of gene expression
1.46 4.62e-03 GO:0002009 morphogenesis of an epithelium
1.30 4.78e-03 GO:0010942 positive regulation of cell death
1.20 4.90e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.11 5.57e-03 GO:0051179 localization
1.26 6.00e-03 GO:0045595 regulation of cell differentiation
2.31 6.01e-03 GO:0010970 microtubule-based transport
2.31 6.01e-03 GO:0030705 cytoskeleton-dependent intracellular transport
1.40 6.67e-03 GO:0051130 positive regulation of cellular component organization
1.30 6.88e-03 GO:0043068 positive regulation of programmed cell death
1.23 6.92e-03 GO:0016265 death
1.15 7.35e-03 GO:0048583 regulation of response to stimulus
1.50 7.42e-03 GO:0035239 tube morphogenesis
1.23 8.12e-03 GO:0008219 cell death
1.66 9.01e-03 GO:0010720 positive regulation of cell development
1.26 9.54e-03 GO:0009790 embryo development
1.30 9.93e-03 GO:0043065 positive regulation of apoptosis
1.23 9.93e-03 GO:0045184 establishment of protein localization
1.22 1.08e-02 GO:0050793 regulation of developmental process
1.29 1.10e-02 GO:0034613 cellular protein localization
1.23 1.12e-02 GO:0022402 cell cycle process
1.21 1.15e-02 GO:0009892 negative regulation of metabolic process
1.21 1.18e-02 GO:0032879 regulation of localization
1.29 1.20e-02 GO:0070727 cellular macromolecule localization
1.29 1.32e-02 GO:0016071 mRNA metabolic process
1.31 1.38e-02 GO:0072358 cardiovascular system development
1.31 1.38e-02 GO:0072359 circulatory system development
1.34 1.41e-02 GO:0009792 embryo development ending in birth or egg hatching
1.32 1.42e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
1.35 1.56e-02 GO:0006917 induction of apoptosis
1.17 1.58e-02 GO:0009056 catabolic process
1.25 1.60e-02 GO:0010628 positive regulation of gene expression
1.20 1.61e-02 GO:0010941 regulation of cell death
1.31 1.64e-02 GO:0048646 anatomical structure formation involved in morphogenesis
1.25 1.66e-02 GO:0019220 regulation of phosphate metabolic process
1.25 1.66e-02 GO:0051174 regulation of phosphorus metabolic process
1.22 1.69e-02 GO:0043933 macromolecular complex subunit organization
1.34 1.70e-02 GO:0043009 chordate embryonic development
1.21 1.76e-02 GO:0042127 regulation of cell proliferation
1.29 1.88e-02 GO:0006974 response to DNA damage stimulus
1.35 1.94e-02 GO:0012502 induction of programmed cell death
2.01 2.12e-02 GO:0006283 transcription-coupled nucleotide-excision repair
1.25 2.33e-02 GO:0006396 RNA processing
1.24 2.37e-02 GO:0065003 macromolecular complex assembly
1.22 2.45e-02 GO:0015031 protein transport
1.41 2.62e-02 GO:0046578 regulation of Ras protein signal transduction
1.09 2.63e-02 GO:0051716 cellular response to stimulus
1.45 2.92e-02 GO:0045664 regulation of neuron differentiation
1.38 3.16e-02 GO:0051960 regulation of nervous system development
1.29 3.18e-02 GO:0006325 chromatin organization
1.22 3.99e-02 GO:0031328 positive regulation of cellular biosynthetic process
1.38 4.02e-02 GO:0010608 posttranscriptional regulation of gene expression
1.25 4.24e-02 GO:0045893 positive regulation of transcription, DNA-dependent
1.22 4.34e-02 GO:0031399 regulation of protein modification process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.13 1.81e-63 GO:0005622 intracellular
1.13 2.61e-61 GO:0044424 intracellular part
1.13 3.42e-41 GO:0043226 organelle
1.15 7.98e-41 GO:0043227 membrane-bounded organelle
1.13 1.63e-40 GO:0043229 intracellular organelle
1.15 1.81e-40 GO:0043231 intracellular membrane-bounded organelle
1.21 1.67e-35 GO:0005634 nucleus
1.14 1.14e-32 GO:0005737 cytoplasm
1.31 5.27e-23 GO:0044428 nuclear part
1.33 5.08e-22 GO:0031981 nuclear lumen
1.16 6.28e-21 GO:0044446 intracellular organelle part
1.16 2.16e-20 GO:0044422 organelle part
1.04 2.03e-19 GO:0005623 cell
1.04 2.81e-19 GO:0044464 cell part
1.14 4.65e-18 GO:0044444 cytoplasmic part
1.26 2.01e-17 GO:0070013 intracellular organelle lumen
1.27 4.99e-17 GO:0005829 cytosol
1.25 2.74e-16 GO:0031974 membrane-enclosed lumen
1.34 6.85e-16 GO:0005654 nucleoplasm
1.25 7.48e-16 GO:0043233 organelle lumen
1.18 5.34e-10 GO:0043228 non-membrane-bounded organelle
1.18 5.34e-10 GO:0043232 intracellular non-membrane-bounded organelle
1.42 5.32e-08 GO:0044427 chromosomal part
1.13 1.31e-06 GO:0032991 macromolecular complex
1.36 1.33e-06 GO:0005694 chromosome
1.31 3.86e-06 GO:0015630 microtubule cytoskeleton
1.14 7.98e-06 GO:0043234 protein complex
1.28 3.57e-05 GO:0044451 nucleoplasm part
1.17 7.01e-04 GO:0012505 endomembrane system
1.36 1.23e-03 GO:0005815 microtubule organizing center
1.33 1.37e-03 GO:0045202 synapse
1.45 1.65e-03 GO:0000228 nuclear chromosome
1.16 2.24e-03 GO:0005856 cytoskeleton
1.49 2.79e-03 GO:0044454 nuclear chromosome part
1.46 5.25e-03 GO:0031252 cell leading edge
1.38 1.65e-02 GO:0000785 chromatin
1.18 2.00e-02 GO:0005794 Golgi apparatus
1.23 2.28e-02 GO:0030054 cell junction
1.12 2.86e-02 GO:0031090 organelle membrane
1.64 3.67e-02 GO:0033267 axon part
1.67 4.89e-02 GO:0034399 nuclear periphery
1.19 4.93e-02 GO:0031982 vesicle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.19 4.56e-46 GO:0005515 protein binding
1.10 2.27e-36 GO:0005488 binding
1.18 8.70e-13 GO:0003676 nucleic acid binding
1.21 2.88e-11 GO:0000166 nucleotide binding
1.21 4.45e-11 GO:0003677 DNA binding
1.30 1.20e-08 GO:0030528 transcription regulator activity
1.36 1.31e-08 GO:0043565 sequence-specific DNA binding
1.70 3.64e-07 GO:0005085 guanyl-nucleotide exchange factor activity
1.19 9.30e-07 GO:0035639 purine ribonucleoside triphosphate binding
1.39 2.76e-06 GO:0030695 GTPase regulator activity
1.18 3.16e-06 GO:0017076 purine nucleotide binding
1.18 3.35e-06 GO:0032553 ribonucleotide binding
1.18 3.35e-06 GO:0032555 purine ribonucleotide binding
1.38 4.92e-06 GO:0060589 nucleoside-triphosphatase regulator activity
1.25 1.15e-05 GO:0001071 nucleic acid binding transcription factor activity
1.25 1.15e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.49 1.56e-05 GO:0016881 acid-amino acid ligase activity
1.44 4.40e-05 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.25 5.86e-05 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.27 6.88e-05 GO:0016301 kinase activity
1.49 7.08e-05 GO:0019787 small conjugating protein ligase activity
1.09 1.03e-04 GO:0003824 catalytic activity
1.27 1.86e-04 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.40 3.06e-04 GO:0016563 transcription activator activity
1.42 4.09e-04 GO:0005083 small GTPase regulator activity
1.26 4.13e-04 GO:0019899 enzyme binding
1.17 6.90e-04 GO:0005524 ATP binding
1.16 7.39e-04 GO:0016740 transferase activity
1.47 7.89e-04 GO:0004842 ubiquitin-protein ligase activity
1.48 1.14e-03 GO:0000975 regulatory region DNA binding
1.48 1.14e-03 GO:0001067 regulatory region nucleic acid binding
1.48 1.14e-03 GO:0044212 transcription regulatory region DNA binding
1.32 1.30e-03 GO:0019904 protein domain specific binding
1.17 1.36e-03 GO:0030554 adenyl nucleotide binding
1.31 1.51e-03 GO:0016874 ligase activity
1.17 1.78e-03 GO:0032559 adenyl ribonucleotide binding
1.43 1.84e-03 GO:0016791 phosphatase activity
1.46 3.37e-03 GO:0010843 promoter binding
1.50 6.07e-03 GO:0004721 phosphoprotein phosphatase activity
1.22 7.09e-03 GO:0003723 RNA binding
1.22 1.23e-02 GO:0042802 identical protein binding
1.19 2.03e-02 GO:0030234 enzyme regulator activity
1.24 3.09e-02 GO:0004672 protein kinase activity
1.25 3.65e-02 GO:0008092 cytoskeletal protein binding
1.67 4.69e-02 GO:0005089 Rho guanyl-nucleotide exchange factor activity