Motif ID: TFEB.p2

Z-value: 1.345


Transcription factors associated with TFEB.p2:

Gene SymbolEntrez IDGene Name
TFEB 7942 transcription factor EB



Activity profile for motif TFEB.p2.

activity profile for motif TFEB.p2


Sorted Z-values histogram for motif TFEB.p2

Sorted Z-values for motif TFEB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFEB.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr20_+_43953428 1.710 CTSA
cathepsin A
chr6_-_84994032 1.544 NM_014895
 KIAA1009
KIAA1009
chr20_-_43953036 1.502 NM_080749
 NEURL2
neuralized homolog 2 (Drosophila)
chr1_-_68470585 1.493 NM_001002292
NM_001193334
NM_024911
 WLS


wntless homolog (Drosophila)


chr19_+_10625987 1.485 ILF3
interleukin enhancer binding factor 3, 90kDa
chr10_-_32257693 1.475 ARHGAP12
Rho GTPase activating protein 12
chr13_+_112999538 1.361 LAMP1
lysosomal-associated membrane protein 1
chr20_+_43953606 1.343 CTSA
cathepsin A
chr1_-_11788550 1.332 MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr17_-_7078446 1.329 NM_004422
 DVL2
dishevelled, dsh homolog 2 (Drosophila)
chr19_-_10625449 1.328 LOC147727
hypothetical LOC147727
chr13_+_112999590 1.309 LAMP1
lysosomal-associated membrane protein 1
chr13_+_48582389 1.264 NM_014923
 FNDC3A
fibronectin type III domain containing 3A
chr16_+_28893525 1.264 NM_001142448
NM_001142449
NM_001142450
NM_001142451
NM_032038
 SPIN1
SPNS1




spindlin 1
spinster homolog 1 (Drosophila)




chr16_+_68542126 1.212 NM_001136214
 CLEC18A
C-type lectin domain family 18, member A
chr2_+_176689737 1.202 NM_002148
 HOXD10
homeobox D10
chr5_+_140200995 1.128 NM_018911
NM_031856
 PCDHA8

protocadherin alpha 8

chr17_-_7078304 1.121 DVL2
dishevelled, dsh homolog 2 (Drosophila)
chr17_-_7078399 1.108 DVL2
dishevelled, dsh homolog 2 (Drosophila)
chr1_-_202595666 1.064 NM_014935
 PLEKHA6
pleckstrin homology domain containing, family A member 6

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
1.80 9.32e-03 GO:0046907 intracellular transport
1.61 4.20e-02 GO:0051649 establishment of localization in cell
1.60 9.15e-03 GO:0033036 macromolecule localization
1.58 2.04e-02 GO:0051641 cellular localization
1.40 5.56e-03 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.38 9.42e-04 GO:0006807 nitrogen compound metabolic process
1.38 1.80e-03 GO:0034641 cellular nitrogen compound metabolic process
1.34 3.18e-02 GO:0006810 transport
1.34 3.53e-02 GO:0051234 establishment of localization
1.30 4.99e-02 GO:0051179 localization

Gene overrepresentation in compartment category:

Showing 1 to 20 of 27 entries
enrichment   p-value GO term description
7.14 1.01e-02 GO:0033176 proton-transporting V-type ATPase complex
3.21 3.60e-02 GO:0042470 melanosome
3.21 3.60e-02 GO:0048770 pigment granule
2.86 4.85e-03 GO:0005774 vacuolar membrane
2.73 9.77e-03 GO:0044437 vacuolar part
2.71 2.30e-06 GO:0005773 vacuole
2.49 6.66e-04 GO:0000323 lytic vacuole
2.49 6.66e-04 GO:0005764 lysosome
1.90 2.85e-02 GO:0005768 endosome
1.57 2.36e-03 GO:0005654 nucleoplasm
1.51 5.05e-04 GO:0031981 nuclear lumen
1.47 3.23e-04 GO:0044428 nuclear part
1.39 2.21e-02 GO:0005829 cytosol
1.38 1.08e-02 GO:0031974 membrane-enclosed lumen
1.38 1.09e-02 GO:0043233 organelle lumen
1.38 1.42e-02 GO:0070013 intracellular organelle lumen
1.29 9.50e-07 GO:0044444 cytoplasmic part
1.29 6.33e-06 GO:0044422 organelle part
1.29 9.90e-06 GO:0044446 intracellular organelle part
1.26 4.45e-02 GO:0032991 macromolecular complex

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
2.08 1.71e-02 GO:0022804 active transmembrane transporter activity
1.20 3.78e-04 GO:0005515 protein binding
1.09 5.00e-02 GO:0005488 binding