Motif ID: TLX2.p2

Z-value: 1.089


Transcription factors associated with TLX2.p2:

Gene SymbolEntrez IDGene Name
TLX2 3196 T-cell leukemia homeobox 2



Activity profile for motif TLX2.p2.

activity profile for motif TLX2.p2


Sorted Z-values histogram for motif TLX2.p2

Sorted Z-values for motif TLX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TLX2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr21_-_26294332 1.083 APP
amyloid beta (A4) precursor protein
chr1_-_151333624 0.946 NM_001024209
 SPRR2E
small proline-rich protein 2E
chr6_-_32839244 0.934 NM_001198858
 HLA-DQB2
major histocompatibility complex, class II, DQ beta 2
chr2_-_79168626 0.848 NM_006507
 REG1B
regenerating islet-derived 1 beta
chr7_+_31693155 0.843 NM_001145123
NM_006658
 C7orf16

chromosome 7 open reading frame 16

chr12_-_90096275 0.834 NM_133504
NM_133505
NM_133506
NM_133507
 DCN



decorin



chr7_-_32077504 0.790 NM_001191059
NM_005020
 PDE1C

phosphodiesterase 1C, calmodulin-dependent 70kDa

chr2_-_174537021 0.729 NM_001017371
 SP3
Sp3 transcription factor
chr21_-_36870736 0.708 NM_001146077
 CLDN14
claudin 14
chr11_-_71501385 0.703 NM_014042
 C11orf51
chromosome 11 open reading frame 51
chr11_-_8571988 0.701 NM_030906
 STK33
serine/threonine kinase 33
chr7_+_54577512 0.688 NM_182546
 VSTM2A
V-set and transmembrane domain containing 2A
chr10_-_5436781 0.687 NM_001171864
NM_024803
 TUBAL3

tubulin, alpha-like 3

chr4_+_120276386 0.684 NM_016599
 MYOZ2
myozenin 2
chr6_+_26548678 0.669 NM_006994
NM_197974
 BTN3A3

butyrophilin, subfamily 3, member A3

chr6_+_131190237 0.659 NM_001195597
 LOC285733
hypothetical LOC285733
chr10_-_46593923 0.658 NM_001040084
NM_001098845
 ANXA8L2
LOC653110
ANXA8
ANXA8L1
annexin A8-like 2
hypothetical LOC653110
annexin A8
annexin A8-like 1
chr6_+_55300225 0.644 NM_207410
 GFRAL
GDNF family receptor alpha like
chr14_-_35859545 0.641 NM_001144891
NM_016586
 MBIP

MAP3K12 binding inhibitory protein 1

chr2_-_174536761 0.637 SP3
Sp3 transcription factor

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
4.04 3.60e-02 GO:0010043 response to zinc ion
3.59 4.07e-03 GO:0051258 protein polymerization
2.85 1.63e-03 GO:0019080 viral genome expression
2.85 1.63e-03 GO:0019083 viral transcription
2.64 1.23e-02 GO:0006415 translational termination
2.49 2.69e-02 GO:0043241 protein complex disassembly
2.49 2.69e-02 GO:0043624 cellular protein complex disassembly
2.38 3.14e-02 GO:0032984 macromolecular complex disassembly
2.38 3.14e-02 GO:0034623 cellular macromolecular complex disassembly
2.27 1.55e-02 GO:0019058 viral infectious cycle
2.17 4.26e-02 GO:0031016 pancreas development
1.24 4.60e-02 GO:0048518 positive regulation of biological process
1.22 2.49e-02 GO:0048856 anatomical structure development

Gene overrepresentation in compartment category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
3.19 4.61e-02 GO:0022625 cytosolic large ribosomal subunit
2.70 4.64e-03 GO:0022626 cytosolic ribosome
2.09 8.50e-03 GO:0044445 cytosolic part
1.32 2.77e-04 GO:0005829 cytosol
1.22 1.47e-02 GO:0043228 non-membrane-bounded organelle
1.22 1.47e-02 GO:0043232 intracellular non-membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
2.03 4.71e-02 GO:0003735 structural constituent of ribosome