Motif ID: ZBTB16.p2

Z-value: 1.505


Transcription factors associated with ZBTB16.p2:

Gene SymbolEntrez IDGene Name
ZBTB16 7704 zinc finger and BTB domain containing 16



Activity profile for motif ZBTB16.p2.

activity profile for motif ZBTB16.p2


Sorted Z-values histogram for motif ZBTB16.p2

Sorted Z-values for motif ZBTB16.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZBTB16.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_10453409 5.950 NM_013431
KLRC4-KLRK1
KLRC4
KLRC4-KLRK1 read-through transcript
killer cell lectin-like receptor subfamily C, member 4
chr11_-_104332631 5.438 NM_033306
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr12_-_10953427 5.069 NM_023920
TAS2R13
taste receptor, type 2, member 13
chr9_+_104797413 5.055 NM_001340
CYLC2
cylicin, basic protein of sperm head cytoskeleton 2
chr19_-_53444733 4.339 NM_001184901
NM_001184903
NM_014959
CARD8


caspase recruitment domain family, member 8


chr10_-_98315090 4.070 TM9SF3
transmembrane 9 superfamily member 3
chr12_+_14429499 4.003 ATF7IP
activating transcription factor 7 interacting protein
chr4_-_38460983 3.433 NM_001017388
NM_001195106
NM_001195107
NM_001195108
NM_030956
TLR10




toll-like receptor 10




chr8_-_81155564 3.381 NM_001025252
TPD52
tumor protein D52
chr4_-_69852090 3.009 NM_024743
UGT2A3
UDP glucuronosyltransferase 2 family, polypeptide A3
chr15_+_22832198 2.949 SNRPN
small nuclear ribonucleoprotein polypeptide N
chr19_-_20399601 2.891 ZNF826P
zinc finger protein 826, pseudogene
chr9_+_21430439 2.891 NM_024013
IFNA1
interferon, alpha 1
chr11_-_89181390 2.788 NM_020358
TRIM49
tripartite motif containing 49
chr5_-_64813459 2.766 NM_197941
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr1_+_144236398 2.761 ITGA10
integrin, alpha 10
chr10_-_93992982 2.718 NM_001178137
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr9_-_36266930 2.643 NM_001128227
NM_001190388
GNE

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

chr11_+_59920062 2.609 NM_001079692
NM_032597
MS4A14

membrane-spanning 4-domains, subfamily A, member 14

chr9_-_21340885 2.585 NM_021002
IFNA6
interferon, alpha 6
chr4_+_141484046 2.560 NM_001153446
NM_001153635
NM_001153585
NM_001153690
SCOC



short coiled-coil protein



chr1_+_239762179 2.547 NM_003679
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr1_+_144236346 2.541 NM_003637
ITGA10
integrin, alpha 10
chr4_+_71126376 2.501 NM_152997
C4orf7
chromosome 4 open reading frame 7
chr14_+_38772870 2.493 NM_054024
MIA2
melanoma inhibitory activity 2
chr13_-_98708549 2.470 NM_001098200
NM_005292
GPR18

G protein-coupled receptor 18

chr2_+_161701711 2.421 NM_004180
NM_133484
TANK

TRAF family member-associated NFKB activator

chr1_-_167969802 2.374 NM_000450
SELE
selectin E
chr12_-_9987277 2.369 LOC100506159
hypothetical LOC100506159
chr2_+_201833467 2.344 NM_033356
CASP8
caspase 8, apoptosis-related cysteine peptidase
chr12_+_21175394 2.292 NM_006446
SLCO1B1
solute carrier organic anion transporter family, member 1B1
chr3_-_95230143 2.255 NM_001001850
STX19
syntaxin 19
chr7_-_84589182 2.250 NM_152754
SEMA3D
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr12_-_90096275 2.245 NM_133504
NM_133505
NM_133506
NM_133507
DCN



decorin



chr7_+_111879348 2.226 NM_001197079
IFRD1
interferon-related developmental regulator 1
chr1_-_143708467 2.213 NM_001195260
PDE4DIP
phosphodiesterase 4D interacting protein
chr12_+_63510481 2.193


chr7_-_33047042 2.185 NM_001166118
NM_016489
NT5C3

5'-nucleotidase, cytosolic III

chr18_+_606671 2.172 NM_199167
CLUL1
clusterin-like 1 (retinal)
chr4_-_159313613 2.162 NM_001031700
NM_001128424
FAM198B

family with sequence similarity 198, member B

chr19_+_20750949 2.087


chr1_+_51340487 2.082 NM_001136508
C1orf185
chromosome 1 open reading frame 185
chr1_-_111771877 2.079 NM_002557
OVGP1
oviductal glycoprotein 1, 120kDa
chr18_-_62422195 1.947 NM_021153
CDH19
cadherin 19, type 2
chr17_+_58440629 1.945 NM_025185
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr9_-_21229975 1.944 NM_002172
IFNA14
interferon, alpha 14
chr3_-_47073910 1.925 SETD2
SET domain containing 2
chr5_-_94250357 1.914 MCTP1
multiple C2 domains, transmembrane 1
chr9_-_21295311 1.903 NM_002169
IFNA5
interferon, alpha 5
chr8_+_67201684 1.900 NM_033058
NM_184085
NM_184086
NM_184087
TRIM55



tripartite motif containing 55



chr4_+_123311207 1.895 NM_015312
KIAA1109
KIAA1109
chr11_-_104477367 1.883 NM_001007232
CARD17
caspase recruitment domain family, member 17
chr11_+_89403921 1.855 NM_001195234
TRIM49
TRIM49L2
tripartite motif containing 49
tripartite motif containing 49-like 2
chr9_+_122923864 1.839 CEP110
centrosomal protein 110kDa
chr12_-_9777126 1.835 NM_172004
CLECL1
C-type lectin-like 1
chr11_-_111539881 1.821 NM_001562
IL18
interleukin 18 (interferon-gamma-inducing factor)
chr10_+_124141808 1.771 NM_021622
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chrX_+_79562601 1.769 NM_152630
FAM46D
family with sequence similarity 46, member D
chr7_-_92693716 1.754 NM_001039372
HEPACAM2
HEPACAM family member 2
chr12_-_25041639 1.745 NM_001101339
C12orf77
chromosome 12 open reading frame 77
chr1_+_170894780 1.732 NM_000639
FASLG
Fas ligand (TNF superfamily, member 6)
chr1_-_171441234 1.728 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr9_-_133602745 1.713 NM_005312
RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr7_+_28305464 1.698 NM_182899
CREB5
cAMP responsive element binding protein 5
chr4_-_170314382 1.692 SH3RF1
SH3 domain containing ring finger 1
chr19_-_5821546 1.673 NM_002034
FUT5
fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
chr8_+_86287161 1.670 NM_001083589
E2F5
E2F transcription factor 5, p130-binding
chr2_+_105799354 1.666 NCK2
NCK adaptor protein 2
chr6_-_76838944 1.658 NM_001563
IMPG1
interphotoreceptor matrix proteoglycan 1
chr14_-_74669864 1.655 TMED10
transmembrane emp24-like trafficking protein 10 (yeast)
chr3_+_161877640 1.637 NM_025047
ARL14
ADP-ribosylation factor-like 14
chr12_-_10479810 1.633 NM_002260
KLRC2
KLRC3
killer cell lectin-like receptor subfamily C, member 2
killer cell lectin-like receptor subfamily C, member 3
chr6_-_22410993 1.620 NM_001163558
PRL
prolactin
chr13_-_32678142 1.603 NM_052851
STARD13
StAR-related lipid transfer (START) domain containing 13
chr17_+_55098280 1.586 CLTC
clathrin, heavy chain (Hc)
chr12_+_10015274 1.584 NM_138337
NM_201623
CLEC12A

C-type lectin domain family 12, member A

chr11_-_55757236 1.583 NM_001004746
OR5T2
olfactory receptor, family 5, subfamily T, member 2
chr15_+_39839866 1.581 MGA
MAX gene associated
chr9_+_109131814 1.578 RAD23B
RAD23 homolog B (S. cerevisiae)
chr6_+_46869052 1.575 NM_005588
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr1_+_169549996 1.573 NM_002022
FMO4
flavin containing monooxygenase 4
chr10_+_90511142 1.572 NM_001102469
LIPN
lipase, family member N
chr7_-_36730525 1.556 NM_001177506
NM_001177507
NM_001637
AOAH


acyloxyacyl hydrolase (neutrophil)


chr3_+_133798770 1.536 NM_016557
CCRL1
chemokine (C-C motif) receptor-like 1
chr3_+_138132006 1.536 NM_001190796
NCK1
NCK adaptor protein 1
chr3_+_40493605 1.529 NM_001145082
NM_001145093
NM_001145083
ZNF619


zinc finger protein 619


chr21_-_26345294 1.518


chr5_-_74065004 1.518


chr2_+_172530120 1.511 HAT1
histone acetyltransferase 1
chr1_+_78243181 1.499 NM_007034
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr3_+_142175329 1.458 SLC25A36
solute carrier family 25, member 36
chr12_+_43972732 1.456 NM_001142678
ANO6
anoctamin 6
chr10_+_127419021 1.455 C10orf137
chromosome 10 open reading frame 137
chr9_-_36365965 1.448 RNF38
ring finger protein 38
chr18_+_30589937 1.448 NM_001390
NM_001391
DTNA

dystrobrevin, alpha

chr11_-_4933518 1.441 NM_001004748
OR51A2
olfactory receptor, family 51, subfamily A, member 2
chr2_+_228064531 1.441 AGFG1
ArfGAP with FG repeats 1
chr17_-_36436979 1.439 NM_031957
KRTAP1-5
keratin associated protein 1-5
chr17_-_18207416 1.426 NM_004169
NM_148918
SHMT1

serine hydroxymethyltransferase 1 (soluble)

chr9_+_674193 1.423


chr2_-_20375497 1.412 PUM2
pumilio homolog 2 (Drosophila)
chr11_-_104411065 1.410 NM_001223
NM_033292
NM_033293
NM_033294
NM_033295
CASP1




caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)




chr3_+_180548173 1.406 NM_033540
MFN1
mitofusin 1
chr4_-_17415918 1.398 DCAF16
DDB1 and CUL4 associated factor 16
chr3_-_57301749 1.393 NM_001142733
ASB14
ankyrin repeat and SOCS box containing 14
chr11_-_5212168 1.380 NM_000519
HBD
hemoglobin, delta
chr8_+_23157094 1.378 NM_152272
CHMP7
CHMP family, member 7
chr8_-_37847095 1.378 RAB11FIP1
RAB11 family interacting protein 1 (class I)
chrX_+_35847771 1.372 NM_152632
CXorf22
chromosome X open reading frame 22
chr22_-_34564611 1.368 RPL41P5
ribosomal protein L41 pseudogene 5
chr21_-_30774502 1.363 NM_181607
KRTAP19-1
keratin associated protein 19-1
chr19_+_56990222 1.357 NM_002030
FPR3
formyl peptide receptor 3
chr9_-_21197141 1.357 NM_002171
IFNA10
interferon, alpha 10
chr3_+_85858321 1.352 NM_153184
CADM2
cell adhesion molecule 2
chr7_-_18033970 1.351 NM_175886
PRPS1L1
phosphoribosyl pyrophosphate synthetase 1-like 1
chr4_+_71298187 1.348 NM_021225
PROL1
proline rich, lacrimal 1
chr6_-_109810396 1.343 NM_001142401
NM_001142402
NM_001142403
NM_001142404
NM_006016
CD164




CD164 molecule, sialomucin




chr5_-_75044001 1.341 NM_152408
POC5
POC5 centriolar protein homolog (Chlamydomonas)
chr3_+_99334230 1.336 NM_001005338
OR5H1
olfactory receptor, family 5, subfamily H, member 1
chr12_+_32546243 1.334 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr18_-_49944986 1.333 MBD2
methyl-CpG binding domain protein 2
chr10_+_96433240 1.326 NM_000772
NM_001128925
CYP2C18

cytochrome P450, family 2, subfamily C, polypeptide 18

chr11_+_56224436 1.319 NM_001005213
NM_001013358
OR9G1
OR9G9
olfactory receptor, family 9, subfamily G, member 1
olfactory receptor, family 9, subfamily G, member 9
chr2_-_46988449 1.314 MCFD2
multiple coagulation factor deficiency 2
chr10_-_11614279 1.310 NM_001080491
USP6NL
USP6 N-terminal like
chr19_+_20138991 1.306 NM_052852
ZNF486
zinc finger protein 486
chr7_-_14847479 1.305 NM_004080
NM_145695
DGKB

diacylglycerol kinase, beta 90kDa

chr12_-_15757114 1.304 EPS8
epidermal growth factor receptor pathway substrate 8
chrX_-_114158388 1.303 NM_000640
IL13RA2
interleukin 13 receptor, alpha 2
chr5_+_156540425 1.298 NM_005546
ITK
IL2-inducible T-cell kinase
chr12_-_10870134 1.295 NM_023921
TAS2R10
taste receptor, type 2, member 10
chr3_-_158700036 1.292 NM_024621
VEPH1
ventricular zone expressed PH domain homolog 1 (zebrafish)
chr11_+_111551417 1.289 NM_031938
BCO2
beta-carotene oxygenase 2
chr6_-_138581319 1.275 NM_021635
PBOV1
prostate and breast cancer overexpressed 1
chr14_+_88130482 1.273 NM_207662
ZC3H14
zinc finger CCCH-type containing 14
chr16_+_87811585 1.268 NM_182531
ZNF778
zinc finger protein 778
chr8_-_120720200 1.262 NM_001040092
NM_001130863
NM_006209
ENPP2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr6_+_130799954 1.259 NM_052913
TMEM200A
transmembrane protein 200A
chr6_+_154449334 1.256 NM_001145287
OPRM1
opioid receptor, mu 1
chr14_+_38804226 1.256 NM_203354
CTAGE5
CTAGE family, member 5
chr7_-_26202626 1.256 HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr19_-_53912025 1.249 NM_182574
MAMSTR
MEF2 activating motif and SAP domain containing transcriptional regulator
chr4_+_69465107 1.248 NM_014058
TMPRSS11E
transmembrane protease, serine 11E
chr21_+_24722913 1.240 FLJ42200
FLJ42200 protein
chr11_-_1586190 1.240 NM_001012708
KRTAP5-3
keratin associated protein 5-3
chr8_-_59575249 1.239 NM_000780
CYP7A1
cytochrome P450, family 7, subfamily A, polypeptide 1
chr1_+_114298021 1.229 NM_181358
HIPK1
homeodomain interacting protein kinase 1
chr12_-_10464308 1.227 NM_002261
NM_007333
KLRC3

killer cell lectin-like receptor subfamily C, member 3

chr3_+_173954940 1.226 NM_018098
ECT2
epithelial cell transforming sequence 2 oncogene
chr1_+_245779018 1.221 NM_145278
C1orf150
chromosome 1 open reading frame 150
chr1_+_28637247 1.220 NM_023923
PHACTR4
phosphatase and actin regulator 4
chr4_-_177427252 1.216 NM_080874
ASB5
ankyrin repeat and SOCS box containing 5
chr21_+_30895276 1.213 NM_181620
KRTAP22-1
keratin associated protein 22-1
chrX_+_37777730 1.203 NM_001163334
SYTL5
synaptotagmin-like 5
chr4_-_64957595 1.200 NM_001010874
TECRL
trans-2,3-enoyl-CoA reductase-like
chr1_+_161308318 1.195 NM_001113380
RGS4
regulator of G-protein signaling 4
chr3_-_52688768 1.186 NM_018165
NM_181042
PBRM1

polybromo 1

chr5_-_119768430 1.181


chr4_+_113437947 1.163 NM_001102406
NM_025144
ALPK1

alpha-kinase 1

chr9_+_107464558 1.162 NM_005421
TAL2
T-cell acute lymphocytic leukemia 2
chr10_+_5126556 1.152 NM_003739
AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr1_-_100003936 1.145 NM_001013660
FRRS1
ferric-chelate reductase 1
chr10_-_5436781 1.143 NM_001171864
NM_024803
TUBAL3

tubulin, alpha-like 3

chr20_-_31055892 1.141 NM_080675
SUN5
Sad1 and UNC84 domain containing 5
chr19_-_21438525 1.138


chr10_-_32707549 1.138 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr2_-_232034638 1.136 NCL
nucleolin
chr7_+_139750311 1.131 NM_001008749
RAB19
RAB19, member RAS oncogene family
chr8_-_114458557 1.127 NM_198124
CSMD3
CUB and Sushi multiple domains 3
chr5_+_140546839 1.122 NM_019119
PCDHB9
protocadherin beta 9
chr1_+_149275652 1.119 NM_001159642
NM_138278
BNIPL

BCL2/adenovirus E1B 19kD interacting protein like

chr3_+_46258875 1.110 NM_001164680
NM_001837
NM_178328
NM_178329
CCR3



chemokine (C-C motif) receptor 3



chr3_+_99288706 1.109 NM_054106
OR5AC2
olfactory receptor, family 5, subfamily AC, member 2
chr1_+_76024466 1.103 NM_004582
RABGGTB
Rab geranylgeranyltransferase, beta subunit
chr10_+_5126613 1.103 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr7_+_37689903 1.102


chr19_-_19793512 1.101 NM_001099269
NM_001145404
ZNF506

zinc finger protein 506

chr6_-_132980901 1.099 NM_014626
TAAR2
trace amine associated receptor 2
chr13_+_48582389 1.099 NM_014923
FNDC3A
fibronectin type III domain containing 3A
chr19_-_14800275 1.089 NM_017506
OR7A5
olfactory receptor, family 7, subfamily A, member 5
chr19_+_57540493 1.089 NM_173530
ZNF610
zinc finger protein 610
chr4_+_24844749 1.089 NM_018323
PI4K2B
phosphatidylinositol 4-kinase type 2 beta
chr13_+_22653059 1.089 NM_000231
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr1_+_42934910 1.082 YBX1
Y box binding protein 1
chr22_-_15682555 1.075 NM_175878
XKR3
XK, Kell blood group complex subunit-related family, member 3
chr3_-_49372584 1.074 RHOA
ras homolog gene family, member A
chr20_-_44494961 1.070 ELMO2
engulfment and cell motility 2
chr6_+_64289585 1.066 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr12_-_55990512 1.066 NM_014925
R3HDM2
R3H domain containing 2
chr1_+_173111306 1.065 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr7_-_107558021 1.063 NM_007356
LAMB4
laminin, beta 4
chr20_-_43601542 1.061 NM_080827
WFDC6
WAP four-disulfide core domain 6
chr10_+_5126589 1.058 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr4_-_47709717 1.057 NM_000087
CNGA1
cyclic nucleotide gated channel alpha 1
chr11_+_17329714 1.056 DKFZp686O24166
hypothetical protein DKFZp686O24166
chr3_+_142587973 1.054


chr6_-_52060327 1.050 NM_138694
NM_170724
PKHD1

polycystic kidney and hepatic disease 1 (autosomal recessive)

chr7_+_111908143 1.047 NM_001134468
NM_182597
C7orf53

chromosome 7 open reading frame 53

chr8_+_24297742 1.046 NM_001145271
NM_001145272
NM_014479
ADAMDEC1


ADAM-like, decysin 1


chr2_-_73373956 1.037 NM_001965
EGR4
early growth response 4

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.49 1.13e-13 GO:0007606 sensory perception of chemical stimulus
2.55 6.30e-13 GO:0007608 sensory perception of smell
1.88 8.76e-09 GO:0007600 sensory perception
2.01 7.17e-05 GO:0051707 response to other organism
1.85 3.96e-04 GO:0009607 response to biotic stimulus
2.56 6.53e-04 GO:0009615 response to virus
1.61 2.09e-03 GO:0006952 defense response
1.45 2.61e-03 GO:0050877 neurological system process
1.38 6.82e-03 GO:0003008 system process
1.16 8.07e-03 GO:0050896 response to stimulus
4.63 8.25e-03 GO:0060338 regulation of type I interferon-mediated signaling pathway
1.56 2.19e-02 GO:0006955 immune response
1.88 3.04e-02 GO:0031347 regulation of defense response
3.18 3.28e-02 GO:0060337 type I interferon-mediated signaling pathway
3.18 3.28e-02 GO:0071357 cellular response to type I interferon
3.13 4.14e-02 GO:0034340 response to type I interferon

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.22 6.94e-04 GO:0071944 cell periphery
1.22 8.91e-04 GO:0005886 plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.64 2.28e-14 GO:0004984 olfactory receptor activity
1.91 1.12e-10 GO:0004930 G-protein coupled receptor activity
1.56 6.48e-09 GO:0004872 receptor activity
1.64 1.74e-08 GO:0004888 transmembrane receptor activity
1.43 9.21e-07 GO:0004871 signal transducer activity
1.43 9.21e-07 GO:0060089 molecular transducer activity
8.69 5.82e-03 GO:0005132 interferon-alpha/beta receptor binding