Motif ID: ZIC1..3.p2

Z-value: 1.534


Transcription factors associated with ZIC1..3.p2:

Gene SymbolEntrez IDGene Name
ZIC1 7545 Zic family member 1 (odd-paired homolog, Drosophila)
ZIC2 7546 Zic family member 2 (odd-paired homolog, Drosophila)
ZIC3 7547 Zic family member 3 (odd-paired homolog, Drosophila)



Activity profile for motif ZIC1..3.p2.

activity profile for motif ZIC1..3.p2


Sorted Z-values histogram for motif ZIC1..3.p2

Sorted Z-values for motif ZIC1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZIC1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_73756668 2.235 NM_015009
PDZRN3
PDZ domain containing ring finger 3
chr3_+_64645819 1.418 LOC100507098
hypothetical LOC100507098
chr9_+_108665168 1.300 NM_021224
ZNF462
zinc finger protein 462
chr7_-_106088565 1.239 NM_175884
FLJ36031
hypothetical protein FLJ36031
chr10_-_90702490 1.196 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chr5_-_174803768 1.101 NM_000794
DRD1
dopamine receptor D1
chr21_-_27139563 1.095 NM_006988
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr16_-_31390926 1.078


chr7_+_129918408 1.072 NM_177525
MEST
mesoderm specific transcript homolog (mouse)
chr14_+_64077171 1.048 HSPA2
heat shock 70kDa protein 2
chr3_+_155321826 1.023 NM_015595
ARHGEF26
Rho guanine nucleotide exchange factor (GEF) 26
chr12_-_3732614 0.993 NM_001144958
NM_001144959
NM_032680
EFCAB4B


EF-hand calcium binding domain 4B


chr21_+_41461962 0.976 BACE2
beta-site APP-cleaving enzyme 2
chr16_+_65790514 0.951 NM_024712
ELMO3
engulfment and cell motility 3
chr11_+_131285747 0.939 NM_001144058
NM_001144059
NM_016522
NTM


neurotrimin


chr21_-_27139143 0.937 ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr2_+_130846263 0.928 PTPN18
protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
chr12_-_3732478 0.898 EFCAB4B
EF-hand calcium binding domain 4B
chr14_+_64076916 0.894 NM_021979
HSPA2
heat shock 70kDa protein 2
chr11_+_44074322 0.887 NM_000401
EXT2
exostosin 2
chr17_-_53920699 0.827 NM_001080439
HSF5
heat shock transcription factor family member 5
chr16_+_85158357 0.814 NM_005251
FOXC2
forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr1_+_168899936 0.812 NM_006902
NM_022716
PRRX1

paired related homeobox 1

chr1_-_86634511 0.796 NM_001007022
NM_001184765
NM_001184766
NM_020729
ODF2L



outer dense fiber of sperm tails 2-like



chr5_-_121440704 0.793 NM_001178102
LOX
lysyl oxidase
chr22_-_26527469 0.784 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr9_+_99656013 0.782


chrX_-_30237403 0.782 NM_000475
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr5_+_175725050 0.757 NM_173664
ARL10
ADP-ribosylation factor-like 10
chr9_+_111850698 0.736 NM_001004065
NM_001198656
AKAP2

A kinase (PRKA) anchor protein 2

chr1_-_154727014 0.729 MEF2D
myocyte enhancer factor 2D
chr2_+_219991342 0.725 NM_001927
DES
desmin
chr12_-_50871953 0.697 NM_001081492
NM_182507
KRT80

keratin 80

chr8_-_11096257 0.694 NM_173683
XKR6
XK, Kell blood group complex subunit-related family, member 6
chr19_-_12747421 0.672 NM_001100176
NM_013312
HOOK2

hook homolog 2 (Drosophila)

chr13_+_32488477 0.671 NM_004795
KL
klotho
chr17_-_28644118 0.666 NM_183377
ACCN1
amiloride-sensitive cation channel 1, neuronal
chr16_+_31390567 0.662 NM_001042454
NM_001164719
TGFB1I1

transforming growth factor beta 1 induced transcript 1

chr3_+_160964574 0.661 SCHIP1
schwannomin interacting protein 1
chr11_+_19691397 0.658 NM_145117
NM_182964
NAV2

neuron navigator 2

chr21_-_26867138 0.655 NM_052954
CYYR1
cysteine/tyrosine-rich 1
chr19_-_12747263 0.651 HOOK2
hook homolog 2 (Drosophila)
chr20_-_22978141 0.650 NM_000361
THBD
thrombomodulin
chr2_-_133144094 0.648 LYPD1
LY6/PLAUR domain containing 1
chr17_+_6867090 0.620 NM_181844
BCL6B
B-cell CLL/lymphoma 6, member B
chr9_-_72673753 0.617 NM_001007470
NM_020952
NM_024971
NM_206944
NM_206945
NM_206946
NM_206947
NM_206948
TRPM3







transient receptor potential cation channel, subfamily M, member 3







chr14_+_100365162 0.609 MEG3
maternally expressed 3 (non-protein coding)
chr4_+_166519392 0.609 NM_001873
CPE
carboxypeptidase E
chr1_-_29321599 0.609 NM_001171868
TMEM200B
transmembrane protein 200B
chr15_+_81906983 0.601 NM_003027
SH3GL3
SH3-domain GRB2-like 3
chrX_+_101792949 0.599 NM_001099410
NM_001099411
NM_014710
NM_001184727
GPRASP1



G protein-coupled receptor associated sorting protein 1



chr11_-_75057299 0.591 MAP6
microtubule-associated protein 6
chr8_+_76059262 0.579 NM_031461
CRISPLD1
cysteine-rich secretory protein LCCL domain containing 1
chr8_+_31616809 0.576 NM_013962
NRG1
neuregulin 1
chr8_+_42129620 0.572 NM_001134296
NM_006803
AP3M2

adaptor-related protein complex 3, mu 2 subunit

chr3_+_134601479 0.565 NM_003571
BFSP2
beaded filament structural protein 2, phakinin
chr3_+_50272648 0.557


chr2_+_202607554 0.557 NM_003507
FZD7
frizzled homolog 7 (Drosophila)
chr16_+_85169615 0.554 NM_005250
FOXL1
forkhead box L1
chr17_+_6858815 0.553 C17orf49
chromosome 17 open reading frame 49
chr17_+_6867138 0.552 BCL6B
B-cell CLL/lymphoma 6, member B
chr8_+_1937711 0.550 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr13_-_73605914 0.549 NM_007249
KLF12
Kruppel-like factor 12
chr8_+_39084206 0.547 NM_145004
ADAM32
ADAM metallopeptidase domain 32
chr12_-_42231990 0.535 NM_025003
ADAMTS20
ADAM metallopeptidase with thrombospondin type 1 motif, 20
chr1_+_181421796 0.530 NM_005562
NM_018891
LAMC2

laminin, gamma 2

chr3_+_171619346 0.528 NM_005602
CLDN11
claudin 11
chr7_+_114350144 0.526 MDFIC
MyoD family inhibitor domain containing
chr1_+_181422016 0.525 LAMC2
laminin, gamma 2
chr1_-_38285033 0.525 NM_002699
POU3F1
POU class 3 homeobox 1
chr11_-_27697768 0.524 NM_001143807
BDNF
brain-derived neurotrophic factor
chr7_-_92301147 0.521 NM_001259
CDK6
cyclin-dependent kinase 6
chr1_+_218930542 0.519 C1orf115
chromosome 1 open reading frame 115
chr11_-_132318741 0.519 OPCML
opioid binding protein/cell adhesion molecule-like
chr1_-_145110669 0.518 NM_005399
PRKAB2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr18_+_7557313 0.517 NM_001105244
NM_002845
PTPRM

protein tyrosine phosphatase, receptor type, M

chr19_-_56147971 0.510 NM_001077491
NM_001077492
NM_012427
KLK5


kallikrein-related peptidase 5


chr4_+_72271218 0.508 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr5_-_92982927 0.502


chr8_-_17599438 0.500 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr16_+_54070302 0.498 NM_004530
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr1_+_181421984 0.497 LAMC2
laminin, gamma 2
chr18_+_17076166 0.496 NM_001142966
GREB1L
growth regulation by estrogen in breast cancer-like
chr8_+_32525269 0.485 NM_001160002
NM_001160004
NM_001160005
NM_001160007
NM_001160008
NM_004495
NM_013956
NM_013957
NM_013958
NM_013960
NM_013964
NRG1










neuregulin 1










chr20_+_19903778 0.484 RIN2
Ras and Rab interactor 2
chr12_-_48902692 0.482 NM_001113547
LIMA1
LIM domain and actin binding 1
chr14_+_85066265 0.482 FLRT2
fibronectin leucine rich transmembrane protein 2
chr19_+_40325993 0.480 NM_022006
FXYD7
FXYD domain containing ion transport regulator 7
chrX_+_149282097 0.478 NM_001177465
MAMLD1
mastermind-like domain containing 1
chr11_+_116608447 0.478 NM_207343
NM_001077239
RNF214

ring finger protein 214

chr6_+_1556543 0.478 FOXC1
forkhead box C1
chr12_+_52653176 0.476 NM_014212
HOXC11
homeobox C11
chr12_+_6517600 0.475


chr10_+_119292699 0.474


chr9_-_34387786 0.472 NM_032596
C9orf24
chromosome 9 open reading frame 24
chr6_-_107542328 0.471 NM_001080450
BEND3
BEN domain containing 3
chr3_+_112273352 0.467 PVRL3
poliovirus receptor-related 3
chr9_-_112840064 0.467 NM_001401
NM_057159
LPAR1

lysophosphatidic acid receptor 1

chr7_+_79602023 0.467 NM_002069
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chrX_-_48818585 0.466 NM_007213
PRAF2
PRA1 domain family, member 2
chr19_-_45888259 0.465 NM_004756
NUMBL
numb homolog (Drosophila)-like
chr21_+_41461924 0.462 BACE2
beta-site APP-cleaving enzyme 2
chr7_-_27191287 0.461 NM_005523
HOXA11
homeobox A11
chr1_+_86942874 0.460 SH3GLB1
SH3-domain GRB2-like endophilin B1
chr21_-_26465005 0.460 NM_000484
NM_001136129
NM_001136130
NM_201413
NM_201414
APP




amyloid beta (A4) precursor protein




chr10_-_103593529 0.459 NM_014591
NM_173191
NM_173192
NM_173193
NM_173195
NM_173197
KCNIP2





Kv channel interacting protein 2





chr1_+_86942810 0.456 NM_016009
SH3GLB1
SH3-domain GRB2-like endophilin B1
chr21_-_26464790 0.456 APP
amyloid beta (A4) precursor protein
chr21_-_26464931 0.452 APP
amyloid beta (A4) precursor protein
chr1_+_86943074 0.451 SH3GLB1
SH3-domain GRB2-like endophilin B1
chr19_+_7505590 0.449 NM_001166111
NM_001166113
PNPLA6

patatin-like phospholipase domain containing 6

chr21_-_26464915 0.448 APP
amyloid beta (A4) precursor protein
chr14_-_50631407 0.445 TRIM9
tripartite motif containing 9
chr5_-_156935283 0.444


chr1_-_212791188 0.443 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr11_+_124115051 0.439 NRGN
neurogranin (protein kinase C substrate, RC3)
chr4_-_140696740 0.439 NM_030648
SETD7
SET domain containing (lysine methyltransferase) 7
chr5_-_138758783 0.436 NM_001161546
LOC389333
hypothetical protein LOC389333
chr13_-_74953873 0.432 NM_014832
TBC1D4
TBC1 domain family, member 4
chr8_-_97242119 0.430 NM_001001557
GDF6
growth differentiation factor 6
chrX_+_90576252 0.428 NM_080832
PABPC5
poly(A) binding protein, cytoplasmic 5
chr11_-_75057062 0.426 NM_033063
NM_207577
MAP6

microtubule-associated protein 6

chr3_+_49566901 0.421 NM_003458
BSN
bassoon (presynaptic cytomatrix protein)
chr5_+_140835788 0.421 PCDHGC3
protocadherin gamma subfamily C, 3
chrX_-_134013644 0.421 NM_001078172
NM_001134321
FAM127B

family with sequence similarity 127, member B

chr16_+_51722285 0.420 CHD9
chromodomain helicase DNA binding protein 9
chr3_+_49034494 0.419 NDUFAF3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chr7_+_27190688 0.419


chrX_+_151991474 0.418 NM_001170944
NM_032882
LOC100287428
PNMA6A
paraneoplastic antigen-like protein 6A related gene
paraneoplastic antigen like 6A
chr12_+_52733927 0.417 NM_153633
HOXC4
HOXC6
homeobox C4
homeobox C6
chr5_-_168660293 0.415 NM_003062
SLIT3
slit homolog 3 (Drosophila)
chr19_+_60844093 0.414 NM_207115
ZNF580
zinc finger protein 580
chr5_+_140835727 0.410 NM_002588
NM_032402
NM_032403
PCDHGC3


protocadherin gamma subfamily C, 3


chr11_+_13646822 0.410 FAR1
fatty acyl CoA reductase 1
chr10_+_68355797 0.408 NM_178011
LRRTM3
leucine rich repeat transmembrane neuronal 3
chr17_-_15185623 0.407 NM_031898
TEKT3
tektin 3
chr1_+_148788410 0.407 NM_019032
NM_025008
ADAMTSL4

ADAMTS-like 4

chr12_-_21985433 0.406 ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr7_-_27180398 0.404 NM_018951
HOXA10
homeobox A10
chr9_-_122516399 0.403 NM_001080497
MEGF9
multiple EGF-like-domains 9
chr6_-_128883125 0.403 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr1_+_64709063 0.403 NM_020925
CACHD1
cache domain containing 1
chr4_+_159311353 0.401 LOC285505
hypothetical protein LOC285505
chr1_+_86943103 0.399 SH3GLB1
SH3-domain GRB2-like endophilin B1
chr2_-_192767844 0.399 NM_016192
TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr16_+_66244314 0.396 RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr9_+_111850770 0.395 AKAP2
A kinase (PRKA) anchor protein 2
chr14_+_100362236 0.395 MEG3
maternally expressed 3 (non-protein coding)
chr6_+_101948102 0.395


chr19_+_7505037 0.392 NM_006702
NM_001166112
PNPLA6

patatin-like phospholipase domain containing 6

chr10_-_71575953 0.392 TYSND1
trypsin domain containing 1
chr7_+_27191534 0.391 HOXA11-AS1
HOXA11 antisense RNA 1 (non-protein coding)
chr17_-_7083321 0.390 NM_024297
PHF23
PHD finger protein 23
chr14_+_102662416 0.386 NM_006291
TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr22_-_49063088 0.385 PLXNB2
plexin B2
chr14_+_100362204 0.385 MEG3
maternally expressed 3 (non-protein coding)
chr11_+_124114985 0.384 NM_001126181
NM_006176
NRGN

neurogranin (protein kinase C substrate, RC3)

chr10_+_8137356 0.380 GATA3
GATA binding protein 3
chr10_-_105352098 0.378 SH3PXD2A
SH3 and PX domains 2A
chrX_-_107866262 0.377 NM_003604
IRS4
insulin receptor substrate 4
chr11_+_13646839 0.374 FAR1
fatty acyl CoA reductase 1
chr7_+_44110527 0.372 AEBP1
AE binding protein 1
chr13_+_41520888 0.370 NM_152910
NM_178009
DGKH

diacylglycerol kinase, eta

chr1_+_110555433 0.368 KCNC4
potassium voltage-gated channel, Shaw-related subfamily, member 4
chr7_+_77005287 0.361 NM_001131008
NM_001131009
PTPN12

protein tyrosine phosphatase, non-receptor type 12

chr10_+_80672842 0.359 ZMIZ1
zinc finger, MIZ-type containing 1
chr13_+_30378311 0.359 NM_032849
C13orf33
chromosome 13 open reading frame 33
chrX_-_37591760 0.359 NM_006520
DYNLT3
dynein, light chain, Tctex-type 3
chr13_-_109236897 0.357 NM_003749
IRS2
insulin receptor substrate 2
chr11_+_13646806 0.356 FAR1
fatty acyl CoA reductase 1
chr2_-_31214788 0.353 GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chrX_+_51653348 0.352 NM_001005333
NM_006986
MAGED1

melanoma antigen family D, 1

chr20_+_61622985 0.352 PPDPF
pancreatic progenitor cell differentiation and proliferation factor homolog (zebrafish)
chr15_+_37660568 0.352 NM_003246
THBS1
thrombospondin 1
chr11_+_122806196 0.351 LOC100128242
hypothetical LOC100128242
chr1_+_153560351 0.350 NM_001105205
RUSC1
RUN and SH3 domain containing 1
chr6_+_17389752 0.349 NM_001143942
RBM24
RNA binding motif protein 24
chr7_-_37454933 0.347 NM_014800
ELMO1
engulfment and cell motility 1
chr4_-_120767777 0.346 NM_033430
PDE5A
phosphodiesterase 5A, cGMP-specific
chr8_-_22044463 0.346 NM_005144
NM_018411
HR

hairless homolog (mouse)

chr22_-_17891777 0.345 CLDN5
claudin 5
chr6_-_85529884 0.344 TBX18
T-box 18
chr9_+_4480193 0.342 NM_004170
SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr7_-_107883929 0.341 NM_001193582
NM_001193583
NM_001193584
NM_005010
NRCAM



neuronal cell adhesion molecule



chr10_-_62373828 0.341 NM_014836
RHOBTB1
Rho-related BTB domain containing 1
chr1_+_100777044 0.338 GPR88
G protein-coupled receptor 88
chr5_-_156935317 0.335 NM_033274
ADAM19
ADAM metallopeptidase domain 19
chr2_+_182030510 0.333 ITGA4
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr4_-_159311959 0.332 FAM198B
family with sequence similarity 198, member B
chr13_+_102047286 0.331 NM_003291
TPP2
tripeptidyl peptidase II
chr7_-_5535349 0.331 ACTB
actin, beta
chr19_-_53912025 0.330 NM_182574
MAMSTR
MEF2 activating motif and SAP domain containing transcriptional regulator
chr15_-_27901828 0.330 NM_003257
NM_175610
TJP1

tight junction protein 1 (zona occludens 1)

chr12_+_6179736 0.328 NM_001769
CD9
CD9 molecule
chrX_+_104953215 0.326 NRK
Nik related kinase
chr12_+_77782648 0.325 SYT1
synaptotagmin I
chr5_-_58607673 0.324 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr6_+_72653420 0.321 RIMS1
regulating synaptic membrane exocytosis 1
chr17_-_602125 0.320 GEMIN4
gem (nuclear organelle) associated protein 4
chr2_-_175255717 0.320 NM_001077269
WIPF1
WAS/WASL interacting protein family, member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.21 1.19e-11 GO:0050794 regulation of cellular process
1.57 4.79e-11 GO:0009653 anatomical structure morphogenesis
1.32 7.08e-11 GO:0032502 developmental process
1.38 2.52e-10 GO:0048731 system development
1.35 3.26e-10 GO:0048856 anatomical structure development
1.18 3.65e-10 GO:0065007 biological regulation
1.32 9.26e-10 GO:0007275 multicellular organismal development
1.19 9.58e-10 GO:0050789 regulation of biological process
1.51 1.15e-09 GO:0023051 regulation of signaling
1.54 1.29e-09 GO:0007399 nervous system development
1.54 3.37e-09 GO:0009966 regulation of signal transduction
1.41 2.39e-08 GO:0048869 cellular developmental process
1.41 4.58e-08 GO:0030154 cell differentiation
1.43 9.50e-08 GO:0048583 regulation of response to stimulus
1.29 1.67e-07 GO:0016043 cellular component organization
1.62 2.70e-07 GO:0022008 neurogenesis
1.64 3.65e-07 GO:0048699 generation of neurons
1.27 1.09e-06 GO:0031323 regulation of cellular metabolic process
1.27 2.90e-06 GO:0071840 cellular component organization or biogenesis
1.10 3.12e-06 GO:0009987 cellular process
1.31 3.36e-06 GO:0048518 positive regulation of biological process
1.25 4.27e-06 GO:0023052 signaling
1.64 7.49e-06 GO:0010557 positive regulation of macromolecule biosynthetic process
1.33 7.62e-06 GO:0048522 positive regulation of cellular process
1.59 9.76e-06 GO:0009891 positive regulation of biosynthetic process
1.47 1.09e-05 GO:0009893 positive regulation of metabolic process
1.65 1.21e-05 GO:0030182 neuron differentiation
1.30 1.33e-05 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.34 1.42e-05 GO:0048523 negative regulation of cellular process
1.58 1.71e-05 GO:0031328 positive regulation of cellular biosynthetic process
1.51 1.77e-05 GO:0010646 regulation of cell communication
1.30 1.77e-05 GO:0009889 regulation of biosynthetic process
1.90 1.90e-05 GO:0009792 embryo development ending in birth or egg hatching
1.30 1.92e-05 GO:0031326 regulation of cellular biosynthetic process
1.29 2.08e-05 GO:0051171 regulation of nitrogen compound metabolic process
1.25 2.38e-05 GO:0080090 regulation of primary metabolic process
1.90 2.43e-05 GO:0043009 chordate embryonic development
1.31 2.87e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.31 3.07e-05 GO:0010556 regulation of macromolecule biosynthetic process
1.23 3.17e-05 GO:0019222 regulation of metabolic process
1.54 3.81e-05 GO:0048468 cell development
1.47 4.44e-05 GO:0010604 positive regulation of macromolecule metabolic process
1.29 4.85e-05 GO:0071842 cellular component organization at cellular level
1.25 6.06e-05 GO:0060255 regulation of macromolecule metabolic process
1.46 6.21e-05 GO:0031325 positive regulation of cellular metabolic process
1.51 1.04e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.73 1.14e-04 GO:0000904 cell morphogenesis involved in differentiation
1.24 2.08e-04 GO:0007165 signal transduction
1.94 3.23e-04 GO:0001944 vasculature development
1.29 3.69e-04 GO:0048519 negative regulation of biological process
1.65 3.73e-04 GO:0048666 neuron development
1.74 4.63e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.63 4.72e-04 GO:0000902 cell morphogenesis
1.54 5.23e-04 GO:0051173 positive regulation of nitrogen compound metabolic process
1.26 5.65e-04 GO:0071841 cellular component organization or biogenesis at cellular level
1.71 5.71e-04 GO:0072358 cardiovascular system development
1.71 5.71e-04 GO:0072359 circulatory system development
2.39 5.90e-04 GO:0034329 cell junction assembly
1.74 7.39e-04 GO:0007409 axonogenesis
1.57 7.59e-04 GO:0009790 embryo development
1.54 7.84e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.23 8.26e-04 GO:0009952 anterior/posterior pattern formation
1.90 8.53e-04 GO:0051270 regulation of cellular component movement
1.27 8.83e-04 GO:0010468 regulation of gene expression
1.29 9.35e-04 GO:0051252 regulation of RNA metabolic process
1.68 9.63e-04 GO:0031175 neuron projection development
1.95 1.03e-03 GO:0030334 regulation of cell migration
1.71 1.03e-03 GO:0048812 neuron projection morphogenesis
1.78 1.15e-03 GO:0048598 embryonic morphogenesis
1.92 1.26e-03 GO:0001568 blood vessel development
1.82 1.35e-03 GO:0007411 axon guidance
2.27 1.36e-03 GO:0034330 cell junction organization
1.58 1.37e-03 GO:0032989 cellular component morphogenesis
1.85 1.59e-03 GO:0022603 regulation of anatomical structure morphogenesis
1.92 1.61e-03 GO:2000145 regulation of cell motility
1.56 1.62e-03 GO:0010628 positive regulation of gene expression
1.29 2.11e-03 GO:0006355 regulation of transcription, DNA-dependent
1.48 2.41e-03 GO:0009888 tissue development
1.82 2.43e-03 GO:0060284 regulation of cell development
2.00 2.88e-03 GO:0048514 blood vessel morphogenesis
1.68 3.16e-03 GO:0023057 negative regulation of signaling
1.68 3.51e-03 GO:0010648 negative regulation of cell communication
1.31 3.52e-03 GO:0006464 protein modification process
1.46 3.60e-03 GO:0050793 regulation of developmental process
1.85 3.65e-03 GO:0040012 regulation of locomotion
1.70 3.70e-03 GO:0009968 negative regulation of signal transduction
1.56 4.07e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.16 4.85e-03 GO:0032501 multicellular organismal process
1.29 6.14e-03 GO:0043412 macromolecule modification
1.50 6.30e-03 GO:2000026 regulation of multicellular organismal development
1.61 6.75e-03 GO:0032990 cell part morphogenesis
1.18 7.49e-03 GO:0051716 cellular response to stimulus
1.91 8.02e-03 GO:0003002 regionalization
1.61 8.39e-03 GO:0048858 cell projection morphogenesis
1.53 8.56e-03 GO:0030030 cell projection organization
2.94 8.75e-03 GO:0010810 regulation of cell-substrate adhesion
1.76 1.20e-02 GO:0001501 skeletal system development
1.99 1.46e-02 GO:0048732 gland development
1.51 1.47e-02 GO:0051254 positive regulation of RNA metabolic process
1.59 1.52e-02 GO:0048585 negative regulation of response to stimulus
1.35 1.59e-02 GO:0051239 regulation of multicellular organismal process
1.51 1.80e-02 GO:0007167 enzyme linked receptor protein signaling pathway
1.41 2.01e-02 GO:0042127 regulation of cell proliferation
2.03 2.04e-02 GO:0030155 regulation of cell adhesion
1.40 2.22e-02 GO:0032879 regulation of localization
2.85 2.62e-02 GO:0042058 regulation of epidermal growth factor receptor signaling pathway
1.75 2.72e-02 GO:0048729 tissue morphogenesis
3.42 2.77e-02 GO:0001952 regulation of cell-matrix adhesion
1.87 2.91e-02 GO:0002009 morphogenesis of an epithelium
1.60 3.03e-02 GO:0061024 membrane organization
1.48 3.23e-02 GO:0045595 regulation of cell differentiation
1.16 3.71e-02 GO:0044260 cellular macromolecule metabolic process
1.56 3.76e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.59 4.54e-02 GO:0016044 cellular membrane organization
1.42 4.76e-02 GO:0040011 locomotion
1.76 4.86e-02 GO:0061061 muscle structure development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.08 5.78e-06 GO:0005622 intracellular
1.08 5.62e-05 GO:0044424 intracellular part
1.29 1.76e-04 GO:0044459 plasma membrane part
1.11 6.44e-04 GO:0005737 cytoplasm
2.14 9.50e-04 GO:0005912 adherens junction
3.39 1.18e-03 GO:0030667 secretory granule membrane
2.34 3.86e-03 GO:0005925 focal adhesion
1.98 5.73e-03 GO:0070161 anchoring junction
6.21 7.14e-03 GO:0043256 laminin complex
2.23 1.09e-02 GO:0005924 cell-substrate adherens junction
1.47 1.39e-02 GO:0030054 cell junction
1.08 1.43e-02 GO:0043229 intracellular organelle
1.08 1.74e-02 GO:0043226 organelle
4.49 1.95e-02 GO:0005605 basal lamina
2.14 2.36e-02 GO:0030055 cell-substrate junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.16 2.49e-07 GO:0005515 protein binding
1.08 6.33e-06 GO:0005488 binding
1.52 1.10e-03 GO:0043565 sequence-specific DNA binding
1.42 1.13e-03 GO:0030528 transcription regulator activity
1.41 2.06e-03 GO:0001071 nucleic acid binding transcription factor activity
1.41 2.06e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.61 5.18e-03 GO:0019904 protein domain specific binding