Motif ID: AHR_ARNT_ARNT2.p2

Z-value: 2.584


Transcription factors associated with AHR_ARNT_ARNT2.p2:

Gene SymbolEntrez IDGene Name
AHR 196 aryl hydrocarbon receptor
ARNT 405 aryl hydrocarbon receptor nuclear translocator
ARNT2 9915 aryl-hydrocarbon receptor nuclear translocator 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
AHRchr7_+_173047070.381.5e-01Click!
ARNT2chr15_+_784836240.361.7e-01Click!
ARNTchr1_-_149115686-0.126.5e-01Click!


Activity profile for motif AHR_ARNT_ARNT2.p2.

activity profile for motif AHR_ARNT_ARNT2.p2


Sorted Z-values histogram for motif AHR_ARNT_ARNT2.p2

Sorted Z-values for motif AHR_ARNT_ARNT2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of AHR_ARNT_ARNT2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_77391525 2.919


chr3_-_162305319 2.533 NM_033169
NM_001038628
NM_003781
NM_033167
NM_033168
B3GALNT1




beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)




chr5_+_151131853 2.153 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr5_+_151131709 1.846 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr14_-_23850466 1.813


chr14_-_23850410 1.796 NM_014430
CIDEB
cell death-inducing DFFA-like effector b
chr14_-_23850481 1.782 CIDEB
cell death-inducing DFFA-like effector b
chr18_-_21184824 1.765


chr19_-_2378581 1.753 TIMM13
translocase of inner mitochondrial membrane 13 homolog (yeast)
chr7_-_131911768 1.714 PLXNA4
plexin A4
chr13_-_39075200 1.700 LHFP
lipoma HMGIC fusion partner
chr11_+_17714070 1.695 NM_001112741
NM_004976
KCNC1

potassium voltage-gated channel, Shaw-related subfamily, member 1

chr14_+_23850494 1.663 NM_001143919
LTB4R
leukotriene B4 receptor
chr5_+_151131655 1.656 NM_005754
NM_198395
G3BP1

GTPase activating protein (SH3 domain) binding protein 1

chr16_+_81218142 1.651 CDH13
cadherin 13, H-cadherin (heart)
chr15_+_81907176 1.628 SH3GL3
SH3-domain GRB2-like 3
chr19_-_2378530 1.621 TIMM13
translocase of inner mitochondrial membrane 13 homolog (yeast)
chr22_-_17891777 1.616 CLDN5
claudin 5
chr2_+_219283751 1.596 NM_014640
TTLL4
tubulin tyrosine ligase-like family, member 4
chr11_-_78829342 1.585 NM_001098816
ODZ4
odz, odd Oz/ten-m homolog 4 (Drosophila)
chr3_-_191321367 1.583 LEPREL1
leprecan-like 1
chr5_+_151131707 1.569 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr18_-_24011349 1.566 NM_001792
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr13_-_39075304 1.505 LHFP
lipoma HMGIC fusion partner
chr5_+_151131704 1.505 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr2_+_219991342 1.496 NM_001927
DES
desmin
chr4_-_57671307 1.496 IGFBP7
insulin-like growth factor binding protein 7
chr4_-_57671273 1.494 NM_001553
IGFBP7
insulin-like growth factor binding protein 7
chr9_-_85342868 1.486 NM_174938
FRMD3
FERM domain containing 3
chr19_-_14062230 1.482 NM_138352
SAMD1
sterile alpha motif domain containing 1
chr11_+_65594361 1.468 NM_018026
PACS1
phosphofurin acidic cluster sorting protein 1
chr4_+_81337663 1.453 NM_001099403
PRDM8
PR domain containing 8
chr18_+_19523526 1.429 NM_001127717
NM_198129
LAMA3

laminin, alpha 3

chr14_-_80757327 1.396 NM_201595
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr5_+_151131676 1.389 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr1_+_77520874 1.366 NM_012093
AK5
adenylate kinase 5
chr11_-_2248374 1.363 ASCL2
achaete-scute complex homolog 2 (Drosophila)
chr7_-_131911808 1.354 NM_001105543
NM_020911
PLXNA4

plexin A4

chr14_+_60045621 1.343 NM_007374
SIX6
SIX homeobox 6
chr19_-_43439011 1.335 NM_033256
PPP1R14A
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr14_-_53491019 1.332 NM_130851
BMP4
bone morphogenetic protein 4
chr12_-_22378833 1.325 NM_003034
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr4_-_57671112 1.320 IGFBP7
insulin-like growth factor binding protein 7
chr4_-_83569853 1.315 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr16_+_81218074 1.310 NM_001257
CDH13
cadherin 13, H-cadherin (heart)
chr13_+_27392136 1.303 NM_000209
PDX1
pancreatic and duodenal homeobox 1
chr6_-_40663089 1.281 NM_020737
LRFN2
leucine rich repeat and fibronectin type III domain containing 2
chr3_+_106568334 1.274 NM_001627
ALCAM
activated leukocyte cell adhesion molecule
chr14_-_64040072 1.269 NM_006977
ZBTB25
zinc finger and BTB domain containing 25
chr9_-_25668230 1.266 TUSC1
tumor suppressor candidate 1
chr3_+_106568243 1.257 ALCAM
activated leukocyte cell adhesion molecule
chr3_-_62334229 1.253 NM_018008
FEZF2
FEZ family zinc finger 2
chr3_-_65999548 1.247 NM_001033057
NM_004742
NM_015520
MAGI1


membrane associated guanylate kinase, WW and PDZ domain containing 1


chr19_-_44032202 1.203 HNRNPL
heterogeneous nuclear ribonucleoprotein L
chr1_+_110494654 1.199 NM_001010898
SLC6A17
solute carrier family 6, member 17
chr8_-_97242119 1.194 NM_001001557
GDF6
growth differentiation factor 6
chr10_-_128884411 1.189 NM_001039762
FAM196A
family with sequence similarity 196, member A
chr15_+_81906983 1.188 NM_003027
SH3GL3
SH3-domain GRB2-like 3
chr1_+_219119623 1.179 HLX
H2.0-like homeobox
chr13_-_32822759 1.179 STARD13
StAR-related lipid transfer (START) domain containing 13
chr5_+_60663842 1.159 NM_020928
ZSWIM6
zinc finger, SWIM-type containing 6
chr19_-_43438818 1.155 PPP1R14A
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr5_-_172687798 1.152 STC2
stanniocalcin 2
chr7_-_27149750 1.135 NM_019102
HOXA5
homeobox A5
chr6_-_85530617 1.135 NM_001080508
TBX18
T-box 18
chr4_-_115120251 1.120 NM_024590
ARSJ
arylsulfatase family, member J
chr13_-_77390907 1.115 NM_001122659
NM_003991
EDNRB

endothelin receptor type B

chr13_-_76358370 1.114 KCTD12
potassium channel tetramerisation domain containing 12
chr19_-_50601406 1.114 NM_001142502
PPP1R13L
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chr7_-_27136876 1.112 NM_002141
HOXA4
homeobox A4
chr7_-_5535726 1.100 ACTB
actin, beta
chr17_-_8000362 1.097 PER1
period homolog 1 (Drosophila)
chr9_-_112381593 1.092 NM_153366
SVEP1
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr1_+_226937732 1.085 RHOU
ras homolog gene family, member U
chr15_-_35177664 1.084 NM_172315
MEIS2
Meis homeobox 2
chr21_-_38210531 1.076 NM_002240
KCNJ6
potassium inwardly-rectifying channel, subfamily J, member 6
chr11_-_2248757 1.068 NM_005170
ASCL2
achaete-scute complex homolog 2 (Drosophila)
chr12_+_58276114 1.057 SLC16A7
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr16_+_65790514 1.049 NM_024712
ELMO3
engulfment and cell motility 3
chr16_-_85099941 1.040 LOC400550
hypothetical LOC400550
chr10_+_105334704 1.037 NEURL
neuralized homolog (Drosophila)
chr1_-_1525309 1.025 LOC643988
hypothetical LOC643988
chr13_+_57105859 1.017 PCDH17
protocadherin 17
chr3_+_16901455 1.012 NM_001144382
PLCL2
phospholipase C-like 2
chr11_-_62136778 1.011 NM_153265
EML3
echinoderm microtubule associated protein like 3
chr10_-_35970363 1.003 NM_031866
FZD8
frizzled homolog 8 (Drosophila)
chr7_+_98084531 1.002 NM_002523
NPTX2
neuronal pentraxin II
chr7_-_5536704 0.991 NM_001101
ACTB
actin, beta
chr20_+_43952997 0.988 NM_000308
NM_001127695
NM_001167594
CTSA


cathepsin A


chr12_-_87498225 0.983 NM_000899
NM_003994
KITLG

KIT ligand

chr13_-_39075355 0.983 NM_005780
LHFP
lipoma HMGIC fusion partner
chr9_+_86473273 0.976 NM_001018064
NM_006180
NTRK2

neurotrophic tyrosine kinase, receptor, type 2

chr2_+_219283928 0.969 TTLL4
tubulin tyrosine ligase-like family, member 4
chr8_+_126079929 0.967 SQLE
squalene epoxidase
chr6_+_126112506 0.966 HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr16_+_65754788 0.964 NM_001040667
NM_001538
HSF4

heat shock transcription factor 4

chr1_-_43196911 0.964 SLC2A1
solute carrier family 2 (facilitated glucose transporter), member 1
chr5_-_142762947 0.963 NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr14_-_80757018 0.962 NM_015859
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr15_-_77169894 0.952 RASGRF1
Ras protein-specific guanine nucleotide-releasing factor 1
chr19_+_50601306 0.947 NM_012099
CD3EAP
CD3e molecule, epsilon associated protein
chr3_+_106568430 0.941 ALCAM
activated leukocyte cell adhesion molecule
chr12_+_48046946 0.933 NM_023071
SPATS2
spermatogenesis associated, serine-rich 2
chr9_+_35648273 0.926 NM_001195200
NM_001195201
NM_001195217
NM_174923
CCDC107



coiled-coil domain containing 107



chr3_-_129024665 0.925 NM_001003794
MGLL
monoglyceride lipase
chr15_-_43602293 0.920 NM_013309
SLC30A4
solute carrier family 30 (zinc transporter), member 4
chr16_-_4263056 0.919 TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr8_+_31616809 0.919 NM_013962
NRG1
neuregulin 1
chr15_+_78775008 0.917 FAM108C1
family with sequence similarity 108, member C1
chr4_-_83570318 0.913 NM_031372
HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr11_-_65304397 0.909 NM_138368
DKFZp761E198
DKFZp761E198 protein
chr13_+_27264779 0.906 NM_145657
GSX1
GS homeobox 1
chr8_+_69026895 0.892 PREX2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr4_-_122063118 0.892 NM_018699
PRDM5
PR domain containing 5
chr1_+_182040837 0.891 RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr11_+_122936145 0.890 GRAMD1B
GRAM domain containing 1B
chr4_-_83569572 0.881 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr10_+_91164418 0.874 IFIT5
interferon-induced protein with tetratricopeptide repeats 5
chr8_-_42870779 0.873 NM_001160223
NM_001160224
NM_001160225
NM_030954
RNF170



ring finger protein 170



chr4_+_126457016 0.867 NM_024582
FAT4
FAT tumor suppressor homolog 4 (Drosophila)
chr10_+_102749597 0.866 LZTS2
leucine zipper, putative tumor suppressor 2
chr13_-_76358433 0.865 NM_138444
KCTD12
potassium channel tetramerisation domain containing 12
chr15_-_35179185 0.865 MEIS2
Meis homeobox 2
chr22_-_34754343 0.862 NM_001082578
NM_001082579
RBFOX2

RNA binding protein, fox-1 homolog (C. elegans) 2

chr13_+_26723689 0.853 NM_000982
RPL21
ribosomal protein L21
chr9_-_139316523 0.853 NM_001004354
NRARP
NOTCH-regulated ankyrin repeat protein
chr1_+_229365296 0.852 NM_001004342
TRIM67
tripartite motif containing 67
chr9_-_109290528 0.852 KLF4
Kruppel-like factor 4 (gut)
chr11_+_61204392 0.843 NM_006133
DAGLA
diacylglycerol lipase, alpha
chr19_-_44032415 0.842 HNRNPL
heterogeneous nuclear ribonucleoprotein L
chr16_+_1763185 0.841 NM_001010865
EME2
essential meiotic endonuclease 1 homolog 2 (S. pombe)
chr19_-_44032388 0.838 HNRNPL
heterogeneous nuclear ribonucleoprotein L
chr3_+_127743868 0.835 CHST13
carbohydrate (chondroitin 4) sulfotransferase 13
chr13_-_37341859 0.828 NM_001135955
NM_001135956
NM_001135957
NM_001135958
NM_003306
NM_016179
TRPC4





transient receptor potential cation channel, subfamily C, member 4





chr5_-_159672060 0.825 NM_024565
CCNJL
cyclin J-like
chr5_-_176663265 0.818 NM_001031677
NM_130781
RAB24

RAB24, member RAS oncogene family

chr11_-_74819165 0.818 NM_001039548
KLHL35
kelch-like 35 (Drosophila)
chr15_+_89300995 0.813 RCCD1
RCC1 domain containing 1
chr4_+_134292630 0.813 PCDH10
protocadherin 10
chr20_+_11819364 0.812 NM_181443
BTBD3
BTB (POZ) domain containing 3
chr11_+_66643311 0.812 NM_012308
KDM2A
lysine (K)-specific demethylase 2A
chr12_-_91063441 0.811 NM_001731
BTG1
B-cell translocation gene 1, anti-proliferative
chr11_-_56848859 0.810 NM_033396
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr7_-_72822471 0.804 NM_001306
CLDN3
claudin 3
chr15_+_89300973 0.802 RCCD1
RCC1 domain containing 1
chr8_-_29262240 0.800 NM_057158
DUSP4
dual specificity phosphatase 4
chr8_+_32525269 0.798 NM_001160002
NM_001160004
NM_001160005
NM_001160007
NM_001160008
NM_004495
NM_013956
NM_013957
NM_013958
NM_013960
NM_013964
NRG1










neuregulin 1










chr17_-_1412774 0.796 NM_006224
PITPNA
phosphatidylinositol transfer protein, alpha
chr10_+_24023680 0.794 NM_001098500
KIAA1217
KIAA1217
chr13_+_50694364 0.793 NM_145019
FAM124A
family with sequence similarity 124A
chr5_-_142763481 0.791 NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr7_-_5536783 0.788 ACTB
actin, beta
chr11_-_63195371 0.782 ATL3
atlastin GTPase 3
chr16_-_1763036 0.779 NM_023936
MRPS34
mitochondrial ribosomal protein S34
chr8_+_120497732 0.776 NM_002514
NOV
nephroblastoma overexpressed gene
chr7_+_113513828 0.773 FOXP2
forkhead box P2
chr3_+_195889845 0.772 FAM43A
family with sequence similarity 43, member A
chr5_+_32747194 0.769 NM_000908
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr7_-_84654106 0.767 SEMA3D
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr19_+_45799060 0.767 NM_001042545
LTBP4
latent transforming growth factor beta binding protein 4
chr15_+_38923470 0.767 NM_003710
NM_181642
SPINT1

serine peptidase inhibitor, Kunitz type 1

chr4_+_158361185 0.763 NM_000826
NM_001083619
NM_001083620
GRIA2


glutamate receptor, ionotropic, AMPA 2


chr8_-_6680429 0.763 NM_207411
XKR5
XK, Kell blood group complex subunit-related family, member 5
chr1_-_37272295 0.761 NM_000831
GRIK3
glutamate receptor, ionotropic, kainate 3
chr12_-_15265490 0.760 NM_001190726
NM_032918
RERG

RAS-like, estrogen-regulated, growth inhibitor

chr9_-_83494198 0.755 TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr5_-_142763252 0.751 NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr4_-_10068055 0.750 NM_053042
ZNF518B
zinc finger protein 518B
chrX_-_83329562 0.749 NM_014496
RPS6KA6
ribosomal protein S6 kinase, 90kDa, polypeptide 6
chr2_-_45090025 0.747 NM_016932
SIX2
SIX homeobox 2
chr8_-_60194099 0.747 NM_014729
TOX
thymocyte selection-associated high mobility group box
chr19_-_44032449 0.743 NM_001533
HNRNPL
heterogeneous nuclear ribonucleoprotein L
chr6_-_107542328 0.732 NM_001080450
BEND3
BEN domain containing 3
chr16_-_69271428 0.728 MTSS1L
metastasis suppressor 1-like
chr17_+_52026058 0.724 NM_005450
NOG
noggin
chr13_+_19430906 0.720 NM_001190965
ZMYM2
zinc finger, MYM-type 2
chr4_-_39655554 0.719 PDS5A
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr11_+_13940715 0.718 SPON1
spondin 1, extracellular matrix protein
chr3_+_64645819 0.713 LOC100507098
hypothetical LOC100507098
chr7_+_36395913 0.708 NM_018685
ANLN
anillin, actin binding protein
chr11_-_44928803 0.706 NM_001076787
NM_006034
TP53I11

tumor protein p53 inducible protein 11

chr13_-_94162249 0.702 NM_007084
SOX21
SRY (sex determining region Y)-box 21
chr6_+_137285071 0.701 NM_001008783
SLC35D3
solute carrier family 35, member D3
chr7_-_93357881 0.695 NM_006528
TFPI2
tissue factor pathway inhibitor 2
chr9_-_109290107 0.689 KLF4
Kruppel-like factor 4 (gut)
chr19_-_10202947 0.689 NM_004230
S1PR2
sphingosine-1-phosphate receptor 2
chr5_-_172688024 0.687 STC2
stanniocalcin 2
chr11_+_62136788 0.687 NM_000327
ROM1
retinal outer segment membrane protein 1
chr8_-_24828134 0.683 NEFM
neurofilament, medium polypeptide
chr1_+_219119468 0.683 HLX
H2.0-like homeobox
chr5_-_142763393 0.682 NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr2_+_29191711 0.677 NM_024692
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr9_-_13269562 0.675 MPDZ
multiple PDZ domain protein
chr6_+_15353681 0.671 JARID2
jumonji, AT rich interactive domain 2
chr2_+_182030510 0.667 ITGA4
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr10_-_102978678 0.666 NM_006562
LBX1
ladybird homeobox 1
chr10_+_102749222 0.666 LZTS2
leucine zipper, putative tumor suppressor 2
chr11_+_94439964 0.666 SRSF8
serine/arginine-rich splicing factor 8
chr4_+_77446906 0.665 STBD1
starch binding domain 1
chr2_-_39040981 0.661 LOC375196
hypothetical LOC375196

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.12 1.88e-13 GO:0009987 cellular process
1.35 1.61e-09 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.18 2.72e-09 GO:0050794 regulation of cellular process
1.25 4.41e-09 GO:0044260 cellular macromolecule metabolic process
1.19 7.12e-09 GO:0044237 cellular metabolic process
1.16 1.83e-08 GO:0065007 biological regulation
1.16 6.18e-08 GO:0050789 regulation of biological process
1.29 6.28e-08 GO:0034641 cellular nitrogen compound metabolic process
1.28 8.38e-08 GO:0060255 regulation of macromolecule metabolic process
1.32 1.53e-07 GO:0071842 cellular component organization at cellular level
1.31 3.01e-07 GO:0071841 cellular component organization or biogenesis at cellular level
1.28 4.54e-07 GO:0006807 nitrogen compound metabolic process
1.25 6.14e-07 GO:0032502 developmental process
1.43 1.51e-06 GO:0007399 nervous system development
1.23 2.74e-06 GO:0019222 regulation of metabolic process
1.33 3.55e-06 GO:0090304 nucleic acid metabolic process
1.26 3.61e-06 GO:0016043 cellular component organization
1.25 4.74e-06 GO:0007275 multicellular organismal development
1.24 6.84e-06 GO:0031323 regulation of cellular metabolic process
1.25 7.82e-06 GO:0071840 cellular component organization or biogenesis
1.36 8.20e-06 GO:0010467 gene expression
1.37 8.80e-06 GO:0016070 RNA metabolic process
1.16 9.60e-06 GO:0044238 primary metabolic process
1.15 1.19e-05 GO:0008152 metabolic process
1.28 1.34e-05 GO:0048731 system development
1.24 1.98e-05 GO:0080090 regulation of primary metabolic process
1.25 5.23e-05 GO:0048856 anatomical structure development
1.58 8.36e-05 GO:0045595 regulation of cell differentiation
1.18 1.17e-04 GO:0043170 macromolecule metabolic process
1.41 1.17e-04 GO:0009893 positive regulation of metabolic process
1.49 1.50e-04 GO:0050793 regulation of developmental process
1.31 1.53e-04 GO:0030154 cell differentiation
1.30 2.39e-04 GO:0048869 cellular developmental process
1.28 3.06e-04 GO:0048519 negative regulation of biological process
1.71 3.13e-04 GO:0007268 synaptic transmission
1.45 4.05e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.29 5.28e-04 GO:0048523 negative regulation of cellular process
1.24 1.55e-03 GO:0031326 regulation of cellular biosynthetic process
1.24 1.63e-03 GO:0009889 regulation of biosynthetic process
1.25 1.78e-03 GO:0010468 regulation of gene expression
1.43 1.82e-03 GO:0032774 RNA biosynthetic process
1.31 2.60e-03 GO:0034645 cellular macromolecule biosynthetic process
1.24 3.89e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.63 4.61e-03 GO:0023057 negative regulation of signaling
1.37 4.94e-03 GO:0031325 positive regulation of cellular metabolic process
1.30 5.07e-03 GO:0009059 macromolecule biosynthetic process
2.83 5.12e-03 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway
1.62 5.16e-03 GO:0010648 negative regulation of cell communication
1.32 5.71e-03 GO:0009653 anatomical structure morphogenesis
1.43 6.20e-03 GO:0006351 transcription, DNA-dependent
1.58 6.93e-03 GO:0019226 transmission of nerve impulse
1.58 6.93e-03 GO:0035637 multicellular organismal signaling
1.37 7.30e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.64 7.51e-03 GO:0009968 negative regulation of signal transduction
1.48 8.59e-03 GO:0019220 regulation of phosphate metabolic process
1.48 8.59e-03 GO:0051174 regulation of phosphorus metabolic process
1.22 9.32e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.24 9.88e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.41 1.05e-02 GO:0022008 neurogenesis
1.45 1.09e-02 GO:2000026 regulation of multicellular organismal development
1.42 1.14e-02 GO:0048699 generation of neurons
1.22 1.15e-02 GO:0048518 positive regulation of biological process
1.24 1.23e-02 GO:0051252 regulation of RNA metabolic process
1.48 1.38e-02 GO:0042325 regulation of phosphorylation
3.36 1.47e-02 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
1.18 1.56e-02 GO:0023052 signaling
1.21 1.71e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.55 1.78e-02 GO:0007417 central nervous system development
1.29 1.90e-02 GO:0006996 organelle organization
1.41 2.09e-02 GO:0009891 positive regulation of biosynthetic process
1.22 2.86e-02 GO:0044267 cellular protein metabolic process
1.23 2.91e-02 GO:0044249 cellular biosynthetic process
1.39 3.11e-02 GO:0048468 cell development
1.61 3.16e-02 GO:0006163 purine nucleotide metabolic process
1.38 3.21e-02 GO:0042127 regulation of cell proliferation
1.30 3.51e-02 GO:0009966 regulation of signal transduction
1.28 3.53e-02 GO:0023051 regulation of signaling
1.41 4.15e-02 GO:0031399 regulation of protein modification process
1.54 4.32e-02 GO:0072358 cardiovascular system development
1.54 4.32e-02 GO:0072359 circulatory system development
1.70 4.35e-02 GO:0051270 regulation of cellular component movement
2.11 4.71e-02 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
1.40 4.72e-02 GO:0031328 positive regulation of cellular biosynthetic process
1.21 4.85e-02 GO:0009058 biosynthetic process
1.18 4.99e-02 GO:0051179 localization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.13 3.54e-19 GO:0005622 intracellular
1.13 5.84e-17 GO:0044424 intracellular part
1.24 4.86e-13 GO:0005634 nucleus
1.13 1.52e-11 GO:0043226 organelle
1.13 1.99e-11 GO:0043229 intracellular organelle
1.15 4.41e-11 GO:0043231 intracellular membrane-bounded organelle
1.15 4.81e-11 GO:0043227 membrane-bounded organelle
1.15 2.38e-10 GO:0005737 cytoplasm
1.36 4.31e-07 GO:0031981 nuclear lumen
1.44 4.54e-07 GO:0005654 nucleoplasm
1.31 5.86e-07 GO:0031974 membrane-enclosed lumen
1.31 1.18e-06 GO:0070013 intracellular organelle lumen
1.31 2.18e-06 GO:0043233 organelle lumen
1.05 5.97e-06 GO:0044464 cell part
1.05 6.27e-06 GO:0005623 cell
1.30 1.59e-05 GO:0044428 nuclear part
1.14 2.40e-04 GO:0044444 cytoplasmic part
1.26 9.92e-04 GO:0005829 cytosol
1.14 1.75e-03 GO:0044446 intracellular organelle part
1.13 3.30e-03 GO:0044422 organelle part
1.40 1.47e-02 GO:0044451 nucleoplasm part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.11 5.78e-14 GO:0005488 binding
1.17 6.48e-10 GO:0005515 protein binding
1.30 5.59e-06 GO:0000166 nucleotide binding
1.48 5.60e-06 GO:0030528 transcription regulator activity
1.22 5.77e-05 GO:0003676 nucleic acid binding
1.42 2.68e-04 GO:0001071 nucleic acid binding transcription factor activity
1.42 2.68e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.51 3.40e-04 GO:0043565 sequence-specific DNA binding
1.39 1.26e-02 GO:0003723 RNA binding