Motif ID: ATF2.p2

Z-value: 1.047


Transcription factors associated with ATF2.p2:

Gene SymbolEntrez IDGene Name
ATF2 1386 activating transcription factor 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ATF2chr2_-_175741096-0.243.8e-01Click!


Activity profile for motif ATF2.p2.

activity profile for motif ATF2.p2


Sorted Z-values histogram for motif ATF2.p2

Sorted Z-values for motif ATF2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_3936460 1.585 NM_001961
EEF2
eukaryotic translation elongation factor 2
chr2_+_5750229 1.163 NM_003108
SOX11
SRY (sex determining region Y)-box 11
chr3_+_141136691 0.954 NM_022131
CLSTN2
calsyntenin 2
chr2_+_10969513 0.883 NM_002236
KCNF1
potassium voltage-gated channel, subfamily F, member 1
chr6_+_39868126 0.823 DAAM2
dishevelled associated activator of morphogenesis 2
chr5_+_14493905 0.790 TRIO
triple functional domain (PTPRF interacting)
chr4_+_3341521 0.779 NM_198227
RGS12
regulator of G-protein signaling 12
chr14_-_49399317 0.773 RN7SL2
RNA, 7SL, cytoplasmic 2
chr6_+_39868116 0.758


chr8_-_117837224 0.743 EIF3H
eukaryotic translation initiation factor 3, subunit H
chr4_-_111777651 0.724 PITX2
paired-like homeodomain 2
chr4_-_111777584 0.724 PITX2
paired-like homeodomain 2
chr8_-_117837240 0.705 NM_003756
EIF3H
eukaryotic translation initiation factor 3, subunit H
chr4_+_145786622 0.700 NM_022475
HHIP
hedgehog interacting protein
chr16_+_27320983 0.697 NM_181078
NM_181079
IL21R

interleukin 21 receptor

chr3_+_50272648 0.697


chr17_+_38306339 0.691 NM_000151
G6PC
glucose-6-phosphatase, catalytic subunit
chr14_-_49122813 0.690 NM_001030001
NM_001032
RPS29

ribosomal protein S29

chr4_-_186693574 0.686 NM_001114107
NM_014476
PDLIM3

PDZ and LIM domain 3

chr6_+_72979234 0.683 NM_001168407
NM_001168408
RIMS1

regulating synaptic membrane exocytosis 1

chr3_-_64186151 0.680 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr11_+_122936145 0.678 GRAMD1B
GRAM domain containing 1B
chr3_-_158360576 0.677 CCNL1
cyclin L1
chr9_-_124066901 0.673 NM_033117
RBM18
RNA binding motif protein 18
chr20_+_32610161 0.663 NM_032514
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr3_+_171558188 0.640 SKIL
SKI-like oncogene
chr4_-_170770111 0.637 NM_012224
NEK1
NIMA (never in mitosis gene a)-related kinase 1
chr11_+_122936246 0.626 GRAMD1B
GRAM domain containing 1B
chr6_-_127822227 0.625 NM_014702
KIAA0408
KIAA0408
chr5_+_140568451 0.618 NM_018932
PCDHB12
protocadherin beta 12
chr3_-_102878301 0.611 NM_014415
ZBTB11
zinc finger and BTB domain containing 11
chr8_-_117837202 0.607 EIF3H
eukaryotic translation initiation factor 3, subunit H
chr7_-_37923040 0.607 NM_003014
SFRP4
secreted frizzled-related protein 4
chr22_+_40286957 0.605 NM_014460
CSDC2
cold shock domain containing C2, RNA binding
chr11_-_107087943 0.596 NM_003063
SLN
sarcolipin
chr3_+_171558143 0.585 NM_001145098
NM_005414
SKIL

SKI-like oncogene

chr2_-_188021117 0.584 NM_005795
CALCRL
calcitonin receptor-like
chr3_+_171558215 0.584 SKIL
SKI-like oncogene
chr9_+_124066973 0.575 MRRF
mitochondrial ribosome recycling factor
chr3_-_102194938 0.571 NM_015429
ABI3BP
ABI family, member 3 (NESH) binding protein
chr8_-_95343716 0.571 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr1_+_66570683 0.561 PDE4B
phosphodiesterase 4B, cAMP-specific
chr9_-_124066838 0.557 RBM18
RNA binding motif protein 18
chr14_+_67156323 0.552 NM_001172
ARG2
arginase, type II
chr14_+_54808624 0.552 NM_152231
FBXO34
F-box protein 34
chr2_+_108637916 0.538 LIMS1
LIMS3
LIM and senescent cell antigen-like domains 1
LIM and senescent cell antigen-like domains 3
chr7_-_37922902 0.536 SFRP4
secreted frizzled-related protein 4
chr12_-_6732392 0.531 MLF2
myeloid leukemia factor 2
chr1_+_11171967 0.526 NM_021146
ANGPTL7
angiopoietin-like 7
chr4_+_120276386 0.522 NM_016599
MYOZ2
myozenin 2
chr6_-_46566969 0.518 RCAN2
regulator of calcineurin 2
chr2_+_108637698 0.517 NM_001193485
LIMS1
LIM and senescent cell antigen-like domains 1
chr8_-_10734700 0.514 NM_017884
PINX1
PIN2/TERF1 interacting, telomerase inhibitor 1
chr2_-_97646758 0.514 ACTR1B
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr4_+_75699652 0.512 NM_001657
AREG
amphiregulin
chr19_-_3936343 0.511 EEF2
eukaryotic translation elongation factor 2
chr20_-_14266200 0.508 NM_013281
NM_198391
FLRT3

fibronectin leucine rich transmembrane protein 3

chr14_+_62740878 0.506 NM_020663
RHOJ
ras homolog gene family, member J
chr7_+_129918408 0.504 NM_177525
MEST
mesoderm specific transcript homolog (mouse)
chr1_-_42157077 0.501 NM_001127714
NM_024503
HIVEP3

human immunodeficiency virus type I enhancer binding protein 3

chr1_-_177106702 0.498 NM_004673
ANGPTL1
angiopoietin-like 1
chr8_-_95343696 0.484 GEM
GTP binding protein overexpressed in skeletal muscle
chr17_+_36515166 0.478 NM_001146041
KRTAP4-9
keratin associated protein 4-9
chr3_-_21767819 0.478 NM_024697
ZNF385D
zinc finger protein 385D
chr14_-_76958984 0.478 NM_138791
NM_001113475
C14orf148

chromosome 14 open reading frame 148

chr8_+_40130143 0.478 NM_020130
C8orf4
chromosome 8 open reading frame 4
chr2_-_97646970 0.475 NM_005735
ACTR1B
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr1_+_161305188 0.472 NM_005613
RGS4
regulator of G-protein signaling 4
chr1_+_66570363 0.469 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chr7_-_137337352 0.469 CREB3L2
cAMP responsive element binding protein 3-like 2
chr5_-_175775966 0.468 CLTB
clathrin, light chain B
chr2_-_224175339 0.452 SCG2
secretogranin II
chr2_+_219991342 0.451 NM_001927
DES
desmin
chr6_+_42896771 0.449 NM_015349
KIAA0240
KIAA0240
chr7_+_89681069 0.442 NM_001040666
STEAP2
six transmembrane epithelial antigen of the prostate 2
chr10_+_22674379 0.442 NM_012443
NM_172242
SPAG6

sperm associated antigen 6

chr8_-_72436832 0.440 EYA1
eyes absent homolog 1 (Drosophila)
chr14_-_79748273 0.437 NM_000793
NM_013989
DIO2

deiodinase, iodothyronine, type II

chr10_+_95838801 0.435 NM_001165979
PLCE1
phospholipase C, epsilon 1
chr7_-_137337354 0.435 NM_194071
CREB3L2
cAMP responsive element binding protein 3-like 2
chr1_-_84928473 0.431 NM_001166295
NM_001166417
NM_001166293
NM_001166294
NM_014021
SSX2IP




synovial sarcoma, X breakpoint 2 interacting protein




chr7_-_137337318 0.431 CREB3L2
cAMP responsive element binding protein 3-like 2
chr4_+_48527798 0.429 NM_001079840
NM_001079841
NM_017830
NM_001079839
NM_001079842
NM_001168254
OCIAD1





OCIA domain containing 1





chr16_-_74214654 0.429 NM_012091
ADAT1
adenosine deaminase, tRNA-specific 1
chr12_+_55201854 0.423 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr9_-_32991518 0.419 NM_001195249
NM_001195254
NM_001195248
NM_001195250
NM_001195251
NM_001195252
NM_175069
NM_175073
APTX







aprataxin







chr7_+_28415495 0.419 LOC401317
hypothetical LOC401317
chr20_+_10147455 0.410 NM_003081
NM_130811
SNAP25

synaptosomal-associated protein, 25kDa

chr1_+_242281175 0.406 NM_205768
ZNF238
zinc finger protein 238
chr4_-_1980756 0.405 NM_005663
WHSC2
Wolf-Hirschhorn syndrome candidate 2
chr15_+_66658626 0.402 NM_006091
CORO2B
coronin, actin binding protein, 2B
chr2_-_224175293 0.399 SCG2
secretogranin II
chr15_-_56145140 0.398 NM_003888
NM_170696
ALDH1A2

aldehyde dehydrogenase 1 family, member A2

chr5_-_175776137 0.397 NM_001834
NM_007097
CLTB

clathrin, light chain B

chr3_+_142569988 0.396 ZBTB38
zinc finger and BTB domain containing 38
chr8_-_72437020 0.394 NM_000503
EYA1
eyes absent homolog 1 (Drosophila)
chr19_+_40795456 0.391 NM_015302
HAUS5
HAUS augmin-like complex, subunit 5
chr3_-_188870799 0.390 NM_001048
SST
somatostatin
chr14_+_54102518 0.389 LOC644925
hypothetical LOC644925
chr4_+_75529716 0.386 NM_001657
AREG
amphiregulin
chrX_+_12903145 0.384 NM_021109
NM_183049
TMSB4X
TMSL3
thymosin beta 4, X-linked
thymosin-like 3
chr1_+_29435534 0.383 NM_001195001
NM_005704
NM_133177
NM_133178
PTPRU



protein tyrosine phosphatase, receptor type, U



chr18_+_75261231 0.383 NM_172387
NM_172389
NFATC1

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

chr13_-_27967215 0.379 NM_001159920
NM_001160030
NM_001160031
NM_002019
FLT1



fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)



chr3_+_142939725 0.377 NM_014245
NM_183237
RNF7

ring finger protein 7

chr8_-_10734792 0.375 PINX1
PIN2/TERF1 interacting, telomerase inhibitor 1
chr20_+_18742369 0.375 NM_178483
C20orf79
chromosome 20 open reading frame 79
chr4_-_96689373 0.375 NM_003728
UNC5C
unc-5 homolog C (C. elegans)
chr19_+_50196526 0.373 NM_006509
RELB
v-rel reticuloendotheliosis viral oncogene homolog B
chr4_-_142273881 0.372 NM_020724
RNF150
ring finger protein 150
chr15_-_75259714 0.371 PEAK1
NKF3 kinase family member
chr21_-_43671355 0.369 NM_173354
SIK1
salt-inducible kinase 1
chr11_+_35596310 0.367 NM_014344
FJX1
four jointed box 1 (Drosophila)
chr5_-_94443300 0.366 NM_001002796
MCTP1
multiple C2 domains, transmembrane 1
chr9_+_17568952 0.363 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr4_-_54119123 0.361 LNX1
ligand of numb-protein X 1
chr20_+_56369012 0.359


chr5_-_94250357 0.359 MCTP1
multiple C2 domains, transmembrane 1
chr6_+_134800533 0.358 LOC154092
hypothetical LOC154092
chr5_+_54491702 0.356 NM_001008397
GPX8
glutathione peroxidase 8 (putative)
chr12_-_123568781 0.355


chr20_+_42644633 0.353 PKIG
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr4_-_54119159 0.352 NM_032622
LNX1
ligand of numb-protein X 1
chr12_-_49076658 0.352 NM_001145475
FAM186A
family with sequence similarity 186, member A
chr3_+_141136896 0.352 CLSTN2
calsyntenin 2
chr4_-_156517544 0.348 NM_001039580
MAP9
microtubule-associated protein 9
chr8_-_42184194 0.348 PLAT
plasminogen activator, tissue
chr1_+_149877955 0.342 SNX27
sorting nexin family member 27
chr12_+_84792203 0.341 NM_006183
NTS
neurotensin
chr11_+_61204392 0.339 NM_006133
DAGLA
diacylglycerol lipase, alpha
chr3_+_142939800 0.336 RNF7
ring finger protein 7
chr8_+_134272463 0.333 NM_003882
NM_080838
WISP1

WNT1 inducible signaling pathway protein 1

chr7_-_152004096 0.332 NM_005431
XRCC2
X-ray repair complementing defective repair in Chinese hamster cells 2
chr1_+_65385799 0.330 NM_203464
NM_001005353
AK4

adenylate kinase 4

chr12_-_44407515 0.327 LOC400027
hypothetical LOC400027
chr5_-_95323353 0.327 NM_012081
ELL2
elongation factor, RNA polymerase II, 2
chr21_-_42303517 0.326 NM_001098402
NM_001098403
NM_020727
ZNF295


zinc finger protein 295


chr12_-_6732342 0.325 NM_005439
MLF2
myeloid leukemia factor 2
chr1_+_99502655 0.324 LPPR4
lipid phosphate phosphatase-related protein type 4
chr20_+_55569542 0.323 NM_002591
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr18_+_59374372 0.323 NM_080474
SERPINB12
serpin peptidase inhibitor, clade B (ovalbumin), member 12
chr14_+_100362236 0.323 MEG3
maternally expressed 3 (non-protein coding)
chr17_+_39741306 0.322 NM_001144825
NM_001144826
NM_006695
RUNDC3A


RUN domain containing 3A


chr12_-_90029328 0.315 LUM
lumican
chr17_-_53976681 0.314 NM_001038704
C17orf47
chromosome 17 open reading frame 47
chr4_-_54119102 0.313 LNX1
ligand of numb-protein X 1
chr3_+_142939827 0.310 RNF7
ring finger protein 7
chr3_-_8518327 0.310 LOC100288428
hypothetical LOC100288428
chr13_+_51496679 0.310 NM_021645
ALG11
UTP14C
asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (yeast)
UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
chr4_-_8481085 0.309 ACOX3
acyl-CoA oxidase 3, pristanoyl
chr2_+_167468220 0.308 NM_001079810
NM_152381
XIRP2

xin actin-binding repeat containing 2

chr14_+_100362204 0.306 MEG3
maternally expressed 3 (non-protein coding)
chr11_-_57947358 0.306 NM_001005566
OR5B2
olfactory receptor, family 5, subfamily B, member 2
chr2_+_54638957 0.305 NM_178313
SPTBN1
spectrin, beta, non-erythrocytic 1
chr1_+_242281199 0.303 ZNF238
zinc finger protein 238
chr7_+_113853790 0.301 NM_001172767
NM_148899
FOXP2

forkhead box P2

chr5_+_36642213 0.301 NM_001166696
NM_004172
SLC1A3

solute carrier family 1 (glial high affinity glutamate transporter), member 3

chr2_-_224175386 0.301 NM_003469
SCG2
secretogranin II
chr5_+_112877251 0.299 NM_022828
YTHDC2
YTH domain containing 2
chr1_-_75849350 0.297 NM_001130058
NM_152697
SLC44A5

solute carrier family 44, member 5

chr18_-_21185968 0.295 ZNF521
zinc finger protein 521
chr14_+_19458580 0.293 NM_001005483
OR4K5
olfactory receptor, family 4, subfamily K, member 5
chr16_+_70437394 0.290 NM_001137675
ATXN1L
ataxin 1-like
chr12_+_79625538 0.289 NM_002469
MYF6
myogenic factor 6 (herculin)
chr3_+_171167243 0.289 NM_003262
SEC62
SEC62 homolog (S. cerevisiae)
chr8_-_93181091 0.289 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr10_+_123913094 0.289 NM_006997
NM_206860
TACC2

transforming, acidic coiled-coil containing protein 2

chr2_+_219453487 0.288 NM_025216
WNT10A
wingless-type MMTV integration site family, member 10A
chr1_+_99502435 0.286 NM_001166252
NM_014839
LPPR4

lipid phosphate phosphatase-related protein type 4

chr10_-_90957028 0.286 NM_003956
CH25H
cholesterol 25-hydroxylase
chr3_-_56784634 0.284 NM_001128616
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr9_-_19023183 0.283 NM_153707
FAM154A
family with sequence similarity 154, member A
chr1_+_177261678 0.281 NM_014864
FAM20B
family with sequence similarity 20, member B
chr4_+_170778265 0.281 NM_001829
NM_173872
CLCN3

chloride channel 3

chr5_+_140494971 0.280 NM_015669
PCDHB5
protocadherin beta 5
chr3_+_160473784 0.278 SCHIP1
schwannomin interacting protein 1
chr2_+_220117009 0.278 TMEM198
transmembrane protein 198
chr2_+_206847658 0.278 NM_020923
ZDBF2
zinc finger, DBF-type containing 2
chr3_+_160473729 0.278 NM_001197107
NM_001197108
NM_014575
SCHIP1


schwannomin interacting protein 1


chr4_+_146238818 0.277 ABCE1
ATP-binding cassette, sub-family E (OABP), member 1
chr10_+_68355797 0.276 NM_178011
LRRTM3
leucine rich repeat transmembrane neuronal 3
chr9_-_112139908 0.275 NM_001003936
TXNDC8
thioredoxin domain containing 8 (spermatozoa)
chr3_+_133801670 0.274 NM_178445
CCRL1
chemokine (C-C motif) receptor-like 1
chr19_-_53941835 0.272 NM_182575
IZUMO1
izumo sperm-egg fusion 1
chr17_-_68819713 0.271 NM_012121
CDC42EP4
CDC42 effector protein (Rho GTPase binding) 4
chr4_-_184480572 0.270 NM_001185149
CLDN24
claudin 24
chr9_+_15542871 0.270 NM_173550
C9orf93
chromosome 9 open reading frame 93
chr8_-_66916830 0.267 PDE7A
phosphodiesterase 7A
chrX_+_43399101 0.266 MAOA
monoamine oxidase A
chr11_-_85108030 0.264 NM_001162952
NM_206930
SYTL2

synaptotagmin-like 2

chr4_-_140696740 0.263 NM_030648
SETD7
SET domain containing (lysine methyltransferase) 7
chr2_-_160838397 0.261 RBMS1
RNA binding motif, single stranded interacting protein 1
chr17_-_8092098 0.261 NM_025099
CTC1
CTS telomere maintenance complex component 1
chr9_+_99785405 0.261 ANP32B
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chrX_+_84385693 0.258 ZNF711
zinc finger protein 711
chr9_+_99785277 0.257 NM_006401
ANP32B
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr2_+_220116986 0.256 NM_001005209
TMEM198
transmembrane protein 198
chr2_+_3683660 0.256 NM_018436
ALLC
allantoicase
chr4_-_187884721 0.255


chr2_-_152664056 0.255 CACNB4
calcium channel, voltage-dependent, beta 4 subunit

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.30 2.41e-03 GO:0032502 developmental process
1.33 4.48e-03 GO:0048856 anatomical structure development

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.18 7.23e-04 GO:0005515 protein binding