Motif ID: ATF4.p2

Z-value: 1.241


Transcription factors associated with ATF4.p2:

Gene SymbolEntrez IDGene Name
ATF4 468 activating transcription factor 4 (tax-responsive enhancer element B67)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ATF4chr22_+_38246509-0.165.5e-01Click!


Activity profile for motif ATF4.p2.

activity profile for motif ATF4.p2


Sorted Z-values histogram for motif ATF4.p2

Sorted Z-values for motif ATF4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_139497933 2.959 NM_016217
HECA
headcase homolog (Drosophila)
chrX_-_151996613 1.691 NM_032882
PNMA6A
paraneoplastic antigen like 6A
chrX_+_151991474 1.588 NM_001170944
NM_032882
LOC100287428
PNMA6A
paraneoplastic antigen-like protein 6A related gene
paraneoplastic antigen like 6A
chr5_+_112877251 1.517 NM_022828
YTHDC2
YTH domain containing 2
chr7_-_129379947 1.427 NM_003344
NM_182697
UBE2H

ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)

chr21_+_44033871 1.424 RRP1
ribosomal RNA processing 1 homolog (S. cerevisiae)
chr8_-_145097031 1.405 NM_201380
PLEC
plectin
chr4_-_120595218 1.379


chr9_-_98421894 1.362 NM_003671
NM_033331
CDC14B

CDC14 cell division cycle 14 homolog B (S. cerevisiae)

chr1_+_26368969 1.353 NM_015871
ZNF593
zinc finger protein 593
chr21_+_44033821 1.284 NM_003683
RRP1
ribosomal RNA processing 1 homolog (S. cerevisiae)
chr10_+_134060681 1.217 NM_001098637
NM_138499
PWWP2B

PWWP domain containing 2B

chr11_+_67107852 1.067 GSTP1
glutathione S-transferase pi 1
chr12_+_52665196 1.043 NM_017409
HOXC10
homeobox C10
chr1_+_226712430 1.035 NM_175055
HIST3H2BB
histone cluster 3, H2bb
chr21_-_43671355 0.950 NM_173354
SIK1
salt-inducible kinase 1
chr1_-_226712140 0.950 NM_033445
HIST3H2A
histone cluster 3, H2a
chr7_-_44992729 0.938 C7orf40
chromosome 7 open reading frame 40
chr22_-_17546296 0.933 NM_005984
SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chrX_-_47364173 0.928 NM_006950
NM_133499
SYN1

synapsin I

chr4_+_75529716 0.928 NM_001657
AREG
amphiregulin
chr12_+_120635021 0.918 NM_001080825
TMEM120B
transmembrane protein 120B
chr4_+_658250 0.913 MYL5
myosin, light chain 5, regulatory
chr7_+_151353707 0.894 NM_022087
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr22_+_19601619 0.874 NM_005207
CRKL
v-crk sarcoma virus CT10 oncogene homolog (avian)-like
chr1_+_29435534 0.868 NM_001195001
NM_005704
NM_133177
NM_133178
PTPRU



protein tyrosine phosphatase, receptor type, U



chr4_+_658312 0.862 MYL5
myosin, light chain 5, regulatory
chr22_-_17546276 0.833 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr22_+_19601721 0.827 CRKL
v-crk sarcoma virus CT10 oncogene homolog (avian)-like
chr1_+_51855343 0.807 OSBPL9
oxysterol binding protein-like 9
chr21_-_43903755 0.804 NM_007031
HSF2BP
heat shock transcription factor 2 binding protein
chr1_-_226357552 0.797 NM_024319
C1orf35
chromosome 1 open reading frame 35
chr12_-_49853155 0.796 NM_001173452
NM_001173453
NM_005653
TFCP2


transcription factor CP2


chr3_+_142143329 0.796 NM_001104647
NM_018155
SLC25A36

solute carrier family 25, member 36

chr8_+_126511739 0.784 NM_025195
TRIB1
tribbles homolog 1 (Drosophila)
chrX_+_48282992 0.779 NM_002536
TBC1D25
TBC1 domain family, member 25
chr4_+_75699652 0.773 NM_001657
AREG
amphiregulin
chr7_-_140270749 0.770 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chr13_+_51275921 0.766


chr7_-_158314945 0.762 ESYT2
extended synaptotagmin-like protein 2
chr22_+_21065202 0.759


chr22_-_17546234 0.749 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr7_+_151353759 0.742 GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr1_-_201162938 0.740 KLHL12
kelch-like 12 (Drosophila)
chr6_+_39868116 0.740


chr10_+_85889164 0.734 NM_014394
GHITM
growth hormone inducible transmembrane protein
chr7_-_158314963 0.725 NM_020728
ESYT2
extended synaptotagmin-like protein 2
chr3_+_42165740 0.712 TRAK1
trafficking protein, kinesin binding 1
chr3_+_141136691 0.707 NM_022131
CLSTN2
calsyntenin 2
chr8_+_23442307 0.706 NM_016612
SLC25A37
solute carrier family 25, member 37
chr6_+_39868126 0.705 DAAM2
dishevelled associated activator of morphogenesis 2
chr9_-_89779180 0.704 CDK20
cyclin-dependent kinase 20
chr1_-_243092581 0.700 HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr1_-_201162991 0.697 NM_021633
KLHL12
kelch-like 12 (Drosophila)
chr4_-_658035 0.683 NM_007100
ATP5I
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E
chr22_-_18807805 0.683 PI4KAP2
PI4KAP1
phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 2
phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 1
chr11_-_61341011 0.682 NM_013402
FADS1
fatty acid desaturase 1
chrX_-_47364039 0.680


chr5_+_139534874 0.679 C5orf32
chromosome 5 open reading frame 32
chr19_-_60587414 0.672 NM_001190764
LOC388564
hypothetical protein LOC388564
chr2_-_87906400 0.668 NM_001078170
RGPD2
RANBP2-like and GRIP domain containing 2
chr19_+_10388448 0.665 PDE4A
phosphodiesterase 4A, cAMP-specific
chr17_+_24095135 0.663 NM_004295
TRAF4
TNF receptor-associated factor 4
chr8_+_23442413 0.624 SLC25A37
solute carrier family 25, member 37
chr18_+_70314562 0.623 CNDP2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr11_+_101723157 0.622 NM_001166
BIRC2
baculoviral IAP repeat containing 2
chr19_-_5291700 0.616 NM_002850
NM_130853
NM_130854
NM_130855
PTPRS



protein tyrosine phosphatase, receptor type, S



chr18_+_70314315 0.615 NM_018235
CNDP2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr1_+_178466064 0.613 NM_033343
LHX4
LIM homeobox 4
chr19_+_1055614 0.598 NM_001039848
GPX4
glutathione peroxidase 4 (phospholipid hydroperoxidase)
chr22_+_22566586 0.592 MIF
macrophage migration inhibitory factor (glycosylation-inhibiting factor)
chr1_-_1274618 0.590 DVL1
dishevelled, dsh homolog 1 (Drosophila)
chr6_-_31882704 0.587 NM_021177
LSM2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr6_-_91063301 0.584 NM_001170794
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr9_-_126991857 0.579 NM_001123355
NM_001123369
NM_002721
PPP6C


protein phosphatase 6, catalytic subunit


chr7_+_55999559 0.579 NM_001483
GBAS
glioblastoma amplified sequence
chr7_+_151353775 0.578 GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr19_+_1199548 0.575 NM_177401
MIDN
midnolin
chr19_-_9407154 0.570 NM_006631
NM_198058
ZNF266

zinc finger protein 266

chr19_+_60688349 0.567 NM_020378
NAT14
N-acetyltransferase 14 (GCN5-related, putative)
chrX_+_48283106 0.560 TBC1D25
TBC1 domain family, member 25
chr16_-_3707450 0.559 NM_016292
TRAP1
TNF receptor-associated protein 1
chr19_+_54226941 0.558 NM_033378
CGB1
CGB2
chorionic gonadotropin, beta polypeptide 1
chorionic gonadotropin, beta polypeptide 2
chr11_+_101723125 0.556 BIRC2
baculoviral IAP repeat containing 2
chr8_+_23442331 0.555 SLC25A37
solute carrier family 25, member 37
chr12_+_111341084 0.554 PTPN11
protein tyrosine phosphatase, non-receptor type 11
chr22_+_22566579 0.550 MIF
macrophage migration inhibitory factor (glycosylation-inhibiting factor)
chr6_-_91063181 0.547 NM_021813
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr7_+_5598964 0.546 FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr9_-_126991805 0.537 PPP6C
protein phosphatase 6, catalytic subunit
chr7_+_38184393 0.526 STARD3NL
STARD3 N-terminal like
chr22_+_22566569 0.526 MIF
macrophage migration inhibitory factor (glycosylation-inhibiting factor)
chr3_+_9950513 0.513 NM_015513
NM_001031717
NM_001077415
CRELD1


cysteine-rich with EGF-like domains 1


chr7_+_5598979 0.501 NM_003088
FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr19_-_52426055 0.501 NM_014417
BBC3
BCL2 binding component 3
chr4_-_1980473 0.499 WHSC2
Wolf-Hirschhorn syndrome candidate 2
chr22_+_21116283 0.498


chr8_+_26204921 0.498 NM_002717
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr8_+_26204960 0.492 PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr1_+_166414706 0.491 NM_001031800
NM_152902
TIPRL

TIP41, TOR signaling pathway regulator-like (S. cerevisiae)

chr3_+_42165829 0.491 TRAK1
trafficking protein, kinesin binding 1
chr5_+_174084137 0.490 NM_002449
MSX2
msh homeobox 2
chr7_+_23187970 0.488 NM_007342
NUPL2
nucleoporin like 2
chr3_+_151609395 0.487 NM_014779
TSC22D2
TSC22 domain family, member 2
chr19_-_18175731 0.487 NM_002866
RAB3A
RAB3A, member RAS oncogene family
chr6_+_33047952 0.485 BRD2
bromodomain containing 2
chr16_+_1696162 0.484 NM_001040439
NM_015133
MAPK8IP3

mitogen-activated protein kinase 8 interacting protein 3

chr7_+_89813977 0.484 GTPBP10
GTP-binding protein 10 (putative)
chr22_+_22566556 0.483 NM_002415
MIF
macrophage migration inhibitory factor (glycosylation-inhibiting factor)
chr16_-_3008162 0.482 NM_021195
CLDN6
claudin 6
chr7_-_64873123 0.482 LOC441242
hypothetical LOC441242
chr19_+_44524939 0.480 NM_018028
SAMD4B
sterile alpha motif domain containing 4B
chr7_+_89813969 0.476 GTPBP10
GTP-binding protein 10 (putative)
chr19_+_44524972 0.475 SAMD4B
sterile alpha motif domain containing 4B
chr2_+_71534260 0.471 NM_001130976
NM_001130977
NM_001130978
NM_001130979
NM_001130980
NM_001130981
NM_003494
DYSF






dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)






chr7_+_20336849 0.470 ITGB8
integrin, beta 8
chr1_-_148079357 0.469 NM_021059
NM_001005464
HIST2H3C
HIST2H3A
histone cluster 2, H3c
histone cluster 2, H3a
chr2_-_96899396 0.468 NM_017789
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr1_+_113300507 0.466 LOC100506392
hypothetical LOC100506392
chr6_-_34468288 0.464 NUDT3
nudix (nucleoside diphosphate linked moiety X)-type motif 3
chr19_+_13124889 0.463 IER2
immediate early response 2
chr16_+_53915971 0.461 NM_024335
IRX6
iroquois homeobox 6
chr11_-_68537243 0.458 NM_001098515
NM_145015
MRGPRF

MAS-related GPR, member F

chr22_+_22566575 0.454


chr3_+_141136896 0.453 CLSTN2
calsyntenin 2
chr1_+_173235193 0.453 NM_001007214
CACYBP
calcyclin binding protein
chr7_+_38184375 0.448 STARD3NL
STARD3 N-terminal like
chr12_+_12935619 0.446 GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr7_-_150847884 0.446 NM_005614
RHEB
Ras homolog enriched in brain
chr1_-_17318452 0.445 NM_007365
PADI2
peptidyl arginine deiminase, type II
chr12_+_12935759 0.443 GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr19_+_44524936 0.443 SAMD4B
sterile alpha motif domain containing 4B
chr1_-_226679648 0.442 NM_003493
HIST3H3
histone cluster 3, H3
chr6_-_34468386 0.441 NUDT3
nudix (nucleoside diphosphate linked moiety X)-type motif 3
chr6_-_90586147 0.440 NM_014611
MDN1
MDN1, midasin homolog (yeast)
chr17_+_22645232 0.437 NM_015626
NM_134265
WSB1

WD repeat and SOCS box containing 1

chr6_-_34772565 0.435 NM_022758
NM_024294
C6orf106

chromosome 6 open reading frame 106

chr1_+_109090876 0.433


chr11_-_61340804 0.433 FADS1
fatty acid desaturase 1
chr7_+_65307691 0.433 NM_003596
TPST1
tyrosylprotein sulfotransferase 1
chr7_+_89813913 0.430 NM_001042717
NM_033107
GTPBP10

GTP-binding protein 10 (putative)

chr11_-_85053807 0.428 NM_001039618
CREBZF
CREB/ATF bZIP transcription factor
chr8_+_98857190 0.427 LAPTM4B
lysosomal protein transmembrane 4 beta
chr3_+_9950474 0.426 CRELD1
cysteine-rich with EGF-like domains 1
chr4_-_113777569 0.425 NM_018392
C4orf21
chromosome 4 open reading frame 21
chr6_-_31882558 0.425 LSM2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr7_-_36372971 0.424 NM_015314
KIAA0895
KIAA0895
chr1_-_113300138 0.424 NM_001166496
SLC16A1
solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
chr12_+_111341139 0.424 PTPN11
protein tyrosine phosphatase, non-receptor type 11
chr4_-_1980756 0.421 NM_005663
WHSC2
Wolf-Hirschhorn syndrome candidate 2
chr6_-_34468416 0.420 NM_006703
NUDT3
nudix (nucleoside diphosphate linked moiety X)-type motif 3
chr4_-_113777470 0.415 C4orf21
chromosome 4 open reading frame 21
chr7_-_45117822 0.414 NM_004749
NM_030900
NM_199122
TBRG4


transforming growth factor beta regulator 4


chr11_+_64448628 0.412 NM_006244
PPP2R5B
protein phosphatase 2, regulatory subunit B', beta
chr3_-_102878301 0.409 NM_014415
ZBTB11
zinc finger and BTB domain containing 11
chr17_-_8092098 0.409 NM_025099
CTC1
CTS telomere maintenance complex component 1
chr17_+_5126275 0.406 NM_001083585
NM_004703
RABEP1

rabaptin, RAB GTPase binding effector protein 1

chr6_-_36915195 0.405 NM_020939
CPNE5
copine V
chr7_-_45117797 0.405 TBRG4
transforming growth factor beta regulator 4
chr18_+_18767275 0.400 NM_002894
RBBP8
retinoblastoma binding protein 8
chr4_-_68898294 0.398 NM_001031732
NM_133370
YTHDC1

YTH domain containing 1

chr22_-_17798998 0.397 HIRA
HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr7_-_124357272 0.396 NM_001042594
NM_015450
POT1

protection of telomeres 1 homolog (S. pombe)

chr5_-_1935764 0.396 NM_016358
IRX4
iroquois homeobox 4
chr22_+_22566595 0.395 MIF
macrophage migration inhibitory factor (glycosylation-inhibiting factor)
chr2_+_96790298 0.395 NM_020184
CNNM4
cyclin M4
chr15_+_71131877 0.394 NM_001172623
NM_001172624
NM_002499
NEO1


neogenin 1


chr2_-_156897286 0.392 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr6_-_3102690 0.391 NM_001069
TUBB2A
tubulin, beta 2A
chr17_+_22645268 0.391 WSB1
WD repeat and SOCS box containing 1
chr15_+_38673509 0.390 CASC5
cancer susceptibility candidate 5
chr4_-_1980500 0.390 WHSC2
Wolf-Hirschhorn syndrome candidate 2
chr14_+_104290561 0.388 SIVA1
SIVA1, apoptosis-inducing factor
chrX_-_134883500 0.387 MMGT1
membrane magnesium transporter 1
chr19_-_60610792 0.385 UBE2S
ubiquitin-conjugating enzyme E2S
chr4_+_110574376 0.385 NM_001042734
NM_006323
SEC24B

SEC24 family, member B (S. cerevisiae)

chr8_+_38763878 0.384 NM_001122824
NM_006283
TACC1

transforming, acidic coiled-coil containing protein 1

chr1_-_21982256 0.383 NM_001032730
NM_032236
USP48

ubiquitin specific peptidase 48

chr4_+_113777568 0.383 NM_016648
LARP7
La ribonucleoprotein domain family, member 7
chr12_+_54946991 0.381 COQ10A
coenzyme Q10 homolog A (S. cerevisiae)
chr16_-_28322441 0.378 EIF3C
eukaryotic translation initiation factor 3, subunit C
chr7_-_150847698 0.377 RHEB
Ras homolog enriched in brain
chr17_-_28644118 0.375 NM_183377
ACCN1
amiloride-sensitive cation channel 1, neuronal
chr1_-_21982192 0.369 USP48
ubiquitin specific peptidase 48
chr22_+_21065134 0.368 LOC100290481
immunoglobulin lambda light chain-like
chr13_-_51276231 0.368 NM_001031719
NM_024705
DHRS12

dehydrogenase/reductase (SDR family) member 12

chr15_+_38673734 0.366 NM_144508
NM_170589
CASC5

cancer susceptibility candidate 5

chr18_+_55718171 0.365 NM_021127
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chr19_+_43557264 0.364 PSMD8
proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
chr7_+_38184363 0.363 STARD3NL
STARD3 N-terminal like
chr7_+_65307816 0.362 TPST1
tyrosylprotein sulfotransferase 1
chr4_+_110574420 0.361 SEC24B
SEC24 family, member B (S. cerevisiae)
chr11_+_66367458 0.361 NM_001032279
NM_005133
RCE1

RCE1 homolog, prenyl protein peptidase (S. cerevisiae)

chr6_+_47553399 0.358 NM_012120
CD2AP
CD2-associated protein
chr7_-_45775066 0.356 SEPT7P2
septin 7 pseudogene 2
chr8_+_38763911 0.356 TACC1
transforming, acidic coiled-coil containing protein 1
chr12_-_91063441 0.354 NM_001731
BTG1
B-cell translocation gene 1, anti-proliferative
chr6_-_105414475 0.353 NM_020771
HACE1
HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1
chr16_+_224834 0.353 ITFG3
integrin alpha FG-GAP repeat containing 3
chr12_+_70519753 0.350 NM_001146213
NM_001146214
NM_022771
TBC1D15


TBC1 domain family, member 15



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.48 6.72e-14 GO:0044260 cellular macromolecule metabolic process
1.43 4.11e-13 GO:0043170 macromolecule metabolic process
1.34 5.41e-12 GO:0044238 primary metabolic process
1.34 8.87e-12 GO:0044237 cellular metabolic process
1.58 2.11e-10 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.51 9.23e-10 GO:0034641 cellular nitrogen compound metabolic process
1.28 1.12e-09 GO:0008152 metabolic process
1.49 2.86e-09 GO:0006807 nitrogen compound metabolic process
1.63 3.79e-09 GO:0090304 nucleic acid metabolic process
1.13 1.79e-05 GO:0009987 cellular process
1.53 7.81e-05 GO:0010467 gene expression
1.44 1.18e-04 GO:0044267 cellular protein metabolic process
1.35 1.79e-04 GO:0071840 cellular component organization or biogenesis
1.54 3.71e-04 GO:0006996 organelle organization
1.39 4.48e-04 GO:0071841 cellular component organization or biogenesis at cellular level
1.51 7.94e-04 GO:0016070 RNA metabolic process
1.33 1.03e-03 GO:0016043 cellular component organization
1.62 1.64e-03 GO:0044248 cellular catabolic process
1.38 1.64e-03 GO:0071842 cellular component organization at cellular level
1.35 2.03e-03 GO:0019538 protein metabolic process
1.64 3.21e-03 GO:0007049 cell cycle
1.86 3.35e-03 GO:0051276 chromosome organization
1.72 5.95e-03 GO:0022402 cell cycle process
1.47 6.12e-03 GO:0034645 cellular macromolecule biosynthetic process
1.47 7.06e-03 GO:0009059 macromolecule biosynthetic process
2.16 1.02e-02 GO:0019941 modification-dependent protein catabolic process
2.15 1.19e-02 GO:0043632 modification-dependent macromolecule catabolic process
1.82 1.28e-02 GO:0006259 DNA metabolic process
1.68 1.31e-02 GO:0033554 cellular response to stress
1.75 1.37e-02 GO:0022403 cell cycle phase
2.15 1.54e-02 GO:0006511 ubiquitin-dependent protein catabolic process
2.11 1.92e-02 GO:0051603 proteolysis involved in cellular protein catabolic process
1.35 2.22e-02 GO:0048522 positive regulation of cellular process
2.07 3.02e-02 GO:0044257 cellular protein catabolic process
1.83 3.52e-02 GO:0044265 cellular macromolecule catabolic process
1.88 3.63e-02 GO:0006325 chromatin organization
1.32 4.93e-02 GO:0009889 regulation of biosynthetic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.21 9.75e-20 GO:0044424 intracellular part
1.20 1.52e-18 GO:0005622 intracellular
1.24 1.26e-16 GO:0043229 intracellular organelle
1.27 1.43e-16 GO:0043231 intracellular membrane-bounded organelle
1.27 1.95e-16 GO:0043227 membrane-bounded organelle
1.24 2.19e-16 GO:0043226 organelle
1.37 6.89e-13 GO:0005634 nucleus
1.36 2.39e-12 GO:0044446 intracellular organelle part
1.35 1.76e-11 GO:0044422 organelle part
1.64 5.22e-11 GO:0070013 intracellular organelle lumen
1.64 1.21e-10 GO:0044428 nuclear part
1.60 3.74e-10 GO:0043233 organelle lumen
1.69 6.52e-10 GO:0031981 nuclear lumen
1.58 1.80e-09 GO:0031974 membrane-enclosed lumen
1.21 4.35e-08 GO:0005737 cytoplasm
1.74 1.09e-07 GO:0005654 nucleoplasm
2.28 4.40e-07 GO:0044427 chromosomal part
2.07 4.91e-06 GO:0005694 chromosome
1.38 8.33e-05 GO:0043228 non-membrane-bounded organelle
1.38 8.33e-05 GO:0043232 intracellular non-membrane-bounded organelle
1.20 1.64e-03 GO:0044444 cytoplasmic part
2.55 1.71e-02 GO:0000775 chromosome, centromeric region
1.25 1.85e-02 GO:0032991 macromolecular complex
6.45 1.87e-02 GO:0000159 protein phosphatase type 2A complex
2.14 2.64e-02 GO:0000785 chromatin
4.04 4.57e-02 GO:0008287 protein serine/threonine phosphatase complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.28 2.58e-11 GO:0005515 protein binding
1.13 2.01e-08 GO:0005488 binding
1.31 1.04e-03 GO:0003676 nucleic acid binding
1.36 3.94e-03 GO:0003677 DNA binding
1.51 4.56e-02 GO:0001071 nucleic acid binding transcription factor activity
1.51 4.56e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.59 4.94e-02 GO:0019899 enzyme binding