Motif ID: ATF5_CREB3.p2

Z-value: 1.655


Transcription factors associated with ATF5_CREB3.p2:

Gene SymbolEntrez IDGene Name
ATF5 22809 activating transcription factor 5
CREB3 10488 cAMP responsive element binding protein 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CREB3chr9_+_357226290.391.4e-01Click!
ATF5chr19_+_551242110.165.6e-01Click!


Activity profile for motif ATF5_CREB3.p2.

activity profile for motif ATF5_CREB3.p2


Sorted Z-values histogram for motif ATF5_CREB3.p2

Sorted Z-values for motif ATF5_CREB3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF5_CREB3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_+_32610161 3.114 NM_032514
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr3_-_102878301 2.846 NM_014415
ZBTB11
zinc finger and BTB domain containing 11
chr4_-_187884721 2.010


chr3_+_141136691 1.522 NM_022131
CLSTN2
calsyntenin 2
chr2_+_10969513 1.436 NM_002236
KCNF1
potassium voltage-gated channel, subfamily F, member 1
chr22_-_42589543 1.422 NM_014351
SULT4A1
sulfotransferase family 4A, member 1
chr3_+_102775677 1.361 PCNP
PEST proteolytic signal containing nuclear protein
chr2_+_108702338 1.302 NM_006267
RANBP2
RAN binding protein 2
chr3_+_101462375 1.284 NM_018309
TBC1D23
TBC1 domain family, member 23
chr4_+_145786622 1.172 NM_022475
HHIP
hedgehog interacting protein
chr14_+_67156323 1.100 NM_001172
ARG2
arginase, type II
chr17_+_37098668 1.050 EIF1
eukaryotic translation initiation factor 1
chr3_+_141136896 1.001 CLSTN2
calsyntenin 2
chr2_-_216009015 0.993 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
FN1





fibronectin 1





chr1_-_212791597 0.969 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr20_-_4177519 0.968 NM_000678
ADRA1D
adrenergic, alpha-1D-, receptor
chr17_+_632356 0.948 RNMTL1
RNA methyltransferase like 1
chr4_-_1980756 0.939 NM_005663
WHSC2
Wolf-Hirschhorn syndrome candidate 2
chr3_-_64186151 0.939 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr1_-_212791467 0.937 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr10_+_102782151 0.900 SFXN3
sideroflexin 3
chr6_-_128883125 0.885 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr12_+_54838408 0.876 MYL6
myosin, light chain 6, alkali, smooth muscle and non-muscle
chr16_+_18986721 0.852 NM_001190983
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr2_+_238200922 0.850 NM_001137550
LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
chr1_+_99502655 0.848 LPPR4
lipid phosphate phosphatase-related protein type 4
chr12_+_52653176 0.847 NM_014212
HOXC11
homeobox C11
chr19_-_50779861 0.844 OPA3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr12_-_6732392 0.838 MLF2
myeloid leukemia factor 2
chr5_+_50714996 0.836 ISL1
ISL LIM homeobox 1
chr1_-_233879617 0.820 NM_001098722
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr9_+_17568952 0.814 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr19_-_50779914 0.809 OPA3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr5_-_57791544 0.808 NM_006622
PLK2
polo-like kinase 2
chr5_-_50714836 0.800 LOC642366
hypothetical LOC642366
chr2_+_118288754 0.796 DDX18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr2_+_118288724 0.791 NM_006773
DDX18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr10_-_90957028 0.789 NM_003956
CH25H
cholesterol 25-hydroxylase
chr2_+_118288753 0.786 DDX18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr3_-_122951200 0.766 NM_004487
GOLGB1
golgin B1
chr11_+_65945050 0.756 NM_178864
NPAS4
neuronal PAS domain protein 4
chr3_-_189354510 0.751 LOC339929
hypothetical LOC339929
chr1_-_20682541 0.737


chr3_-_53900888 0.737 NM_021237
SELK
selenoprotein K
chr3_-_8518327 0.734 LOC100288428
hypothetical LOC100288428
chr6_-_18230829 0.733 NM_198586
NHLRC1
NHL repeat containing 1
chr3_+_8518508 0.732 NM_014583
LMCD1
LIM and cysteine-rich domains 1
chr14_+_37748031 0.731 SSTR1
somatostatin receptor 1
chr3_+_8518539 0.730 LMCD1
LIM and cysteine-rich domains 1
chr12_+_54838361 0.727 NM_021019
NM_079423
MYL6

myosin, light chain 6, alkali, smooth muscle and non-muscle

chr16_+_18986417 0.727 NM_016138
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr20_+_19903778 0.727 RIN2
Ras and Rab interactor 2
chr19_+_50041400 0.724 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr2_-_202353898 0.723 ALS2
amyotrophic lateral sclerosis 2 (juvenile)
chr9_-_85342868 0.722 NM_174938
FRMD3
FERM domain containing 3
chr2_+_28469172 0.719 FOSL2
FOS-like antigen 2
chr5_-_132326872 0.702 AFF4
AF4/FMR2 family, member 4
chr20_+_19863716 0.699 RIN2
Ras and Rab interactor 2
chr14_+_34521854 0.695 NM_001146282
NM_003136
SRP54

signal recognition particle 54kDa

chr22_-_40194602 0.691 NM_032758
PHF5A
PHD finger protein 5A
chr3_+_102775716 0.688 NM_020357
PCNP
PEST proteolytic signal containing nuclear protein
chr20_+_10147455 0.685 NM_003081
NM_130811
SNAP25

synaptosomal-associated protein, 25kDa

chr1_-_95165037 0.684 CNN3
calponin 3, acidic
chr19_+_50041387 0.682 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr3_+_189354167 0.671 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr14_-_22127954 0.665 NM_001344
DAD1
defender against cell death 1
chr14_-_22127902 0.663 DAD1
defender against cell death 1
chr1_+_212227902 0.659 PROX1
prospero homeobox 1
chr12_-_121946581 0.659 VPS37B
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr20_+_5839973 0.657 NM_001819
CHGB
chromogranin B (secretogranin 1)
chr1_-_95165089 0.656 NM_001839
CNN3
calponin 3, acidic
chr4_-_163304567 0.651 NM_001128427
NM_001128428
NM_020116
FSTL5


follistatin-like 5


chr12_+_12935619 0.650 GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr2_-_25048276 0.646 NM_001198559
NM_016544
DNAJC27

DnaJ (Hsp40) homolog, subfamily C, member 27

chr8_-_18915443 0.644 NM_015310
PSD3
pleckstrin and Sec7 domain containing 3
chr14_+_100362236 0.631 MEG3
maternally expressed 3 (non-protein coding)
chr12_-_113606322 0.629 NM_005996
NM_016569
TBX3

T-box 3

chr9_-_124066901 0.626 NM_033117
RBM18
RNA binding motif protein 18
chr9_+_124066973 0.618 MRRF
mitochondrial ribosome recycling factor
chr19_-_50779924 0.616 NM_001017989
NM_025136
OPA3

optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)

chr17_+_632262 0.616 NM_018146
RNMTL1
RNA methyltransferase like 1
chr20_+_36534871 0.616 NM_020336
RALGAPB
Ral GTPase activating protein, beta subunit (non-catalytic)
chr2_-_216008689 0.612 FN1
fibronectin 1
chr5_-_132976094 0.609 FSTL4
follistatin-like 4
chr8_-_74953626 0.606 UBE2W
ubiquitin-conjugating enzyme E2W (putative)
chr19_+_50663089 0.601 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr17_-_632135 0.601 NM_016080
GLOD4
glyoxalase domain containing 4
chr19_+_53641053 0.601 GRWD1
glutamate-rich WD repeat containing 1
chr8_-_74953604 0.600 UBE2W
ubiquitin-conjugating enzyme E2W (putative)
chr2_+_108637916 0.599 LIMS1
LIMS3
LIM and senescent cell antigen-like domains 1
LIM and senescent cell antigen-like domains 3
chr11_+_113435640 0.596 NM_006006
ZBTB16
zinc finger and BTB domain containing 16
chr19_-_62680703 0.595 NM_001024596
NM_001144068
ZNF772

zinc finger protein 772

chr4_-_142273881 0.594 NM_020724
RNF150
ring finger protein 150
chr17_+_15843418 0.593 NM_017775
TTC19
tetratricopeptide repeat domain 19
chr8_-_74953632 0.592 UBE2W
ubiquitin-conjugating enzyme E2W (putative)
chr1_-_16355013 0.591 NM_004431
EPHA2
EPH receptor A2
chr2_+_108637698 0.590 NM_001193485
LIMS1
LIM and senescent cell antigen-like domains 1
chr5_+_50714714 0.590 NM_002202
ISL1
ISL LIM homeobox 1
chr19_+_53641029 0.589 GRWD1
glutamate-rich WD repeat containing 1
chr5_-_100266769 0.585 NM_175052
NM_005668
ST8SIA4

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4

chr12_+_12935222 0.582 NM_003979
GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr19_+_50041424 0.579 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr8_-_24869945 0.579 NM_006158
NEFL
neurofilament, light polypeptide
chr4_+_170778265 0.575 NM_001829
NM_173872
CLCN3

chloride channel 3

chr12_-_6732342 0.574 NM_005439
MLF2
myeloid leukemia factor 2
chr14_+_100362204 0.567 MEG3
maternally expressed 3 (non-protein coding)
chr16_+_18986459 0.565 COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr3_-_192063158 0.564 NM_001146686
GEMC1
geminin coiled-coil domain-containing protein 1
chr5_-_132976121 0.564 NM_015082
FSTL4
follistatin-like 4
chr20_-_55718351 0.562 NM_020182
PMEPA1
prostate transmembrane protein, androgen induced 1
chr2_-_241860871 0.557 HDLBP
high density lipoprotein binding protein
chr12_+_12935759 0.554 GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr14_-_37134191 0.552 NM_004496
FOXA1
forkhead box A1
chr5_+_174084137 0.550 NM_002449
MSX2
msh homeobox 2
chr12_-_112394259 0.549 NM_022363
LHX5
LIM homeobox 5
chr2_-_27967458 0.549 LOC100302650
hypothetical LOC100302650
chr1_+_156229934 0.548 KIRREL
kin of IRRE like (Drosophila)
chr2_-_202354139 0.547 NM_001135745
NM_020919
ALS2

amyotrophic lateral sclerosis 2 (juvenile)

chr8_+_134272463 0.547 NM_003882
NM_080838
WISP1

WNT1 inducible signaling pathway protein 1

chr1_+_161305558 0.547 NM_001113381
RGS4
regulator of G-protein signaling 4
chr8_-_74953648 0.546 UBE2W
ubiquitin-conjugating enzyme E2W (putative)
chr16_+_18902756 0.544 NM_024847
TMC7
transmembrane channel-like 7
chr16_-_10581944 0.540 NM_001424
EMP2
epithelial membrane protein 2
chr3_+_73128771 0.539 NM_174907
PPP4R2
protein phosphatase 4, regulatory subunit 2
chr11_+_113435506 0.537 ZBTB16
zinc finger and BTB domain containing 16
chr1_-_184916044 0.533 NM_000963
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr2_-_10747553 0.533 NM_024894
NOL10
nucleolar protein 10
chr4_+_158216631 0.532 NM_000824
NM_001166061
NM_001166060
GLRB


glycine receptor, beta


chr2_-_10747438 0.530 NOL10
nucleolar protein 10
chr6_+_30702586 0.529 NM_024909
NM_001031722
NM_001190724
ATAT1


alpha tubulin acetyltransferase 1


chr2_+_28469275 0.526 NM_005253
FOSL2
FOS-like antigen 2
chr11_+_12652427 0.525 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr2_+_28469199 0.523 FOSL2
FOS-like antigen 2
chr9_-_74169649 0.522 NM_001102420
NM_001102421
NM_006007
ZFAND5


zinc finger, AN1-type domain 5


chr9_-_124066838 0.513 RBM18
RNA binding motif protein 18
chrX_+_43399101 0.512 MAOA
monoamine oxidase A
chr2_-_241860923 0.510 NM_203346
HDLBP
high density lipoprotein binding protein
chr14_+_34521945 0.509 SRP54
signal recognition particle 54kDa
chr12_-_55013987 0.503 NM_001166279
NM_014871
PAN2

PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)

chr9_+_115023628 0.502 NM_001859
SLC31A1
solute carrier family 31 (copper transporters), member 1
chr6_+_148705817 0.502 SASH1
SAM and SH3 domain containing 1
chr15_+_91248706 0.499 CHD2
chromodomain helicase DNA binding protein 2
chr12_-_45052830 0.497 NM_018976
SLC38A2
solute carrier family 38, member 2
chr5_-_37875538 0.496 NM_000514
GDNF
glial cell derived neurotrophic factor
chr8_-_74953652 0.495 NM_001001481
NM_018299
UBE2W

ubiquitin-conjugating enzyme E2W (putative)

chr8_-_11096257 0.490 NM_173683
XKR6
XK, Kell blood group complex subunit-related family, member 6
chr9_-_32991518 0.490 NM_001195249
NM_001195254
NM_001195248
NM_001195250
NM_001195251
NM_001195252
NM_175069
NM_175073
APTX







aprataxin







chr22_+_36927884 0.487 NM_001161572
NM_001161574
NM_012323
MAFF


v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)


chr9_-_26882713 0.485 NM_001167575
NM_024828
C9orf82

chromosome 9 open reading frame 82

chr7_+_71937980 0.484 SBDSP1
Shwachman-Bodian-Diamond syndrome pseudogene 1
chr4_-_8481085 0.484 ACOX3
acyl-CoA oxidase 3, pristanoyl
chr19_+_53814602 0.482 SPHK2
sphingosine kinase 2
chr1_-_208046011 0.481 NM_006147
IRF6
interferon regulatory factor 6
chr2_+_5750229 0.478 NM_003108
SOX11
SRY (sex determining region Y)-box 11
chr10_+_102782156 0.477 SFXN3
sideroflexin 3
chr4_-_111777584 0.477 PITX2
paired-like homeodomain 2
chr13_-_20533629 0.477 LATS2
LATS, large tumor suppressor, homolog 2 (Drosophila)
chr9_+_91123204 0.474 NM_024077
SECISBP2
SECIS binding protein 2
chr4_-_78216145 0.473 NM_006835
CCNI
cyclin I
chr13_-_20533703 0.471 NM_014572
LATS2
LATS, large tumor suppressor, homolog 2 (Drosophila)
chr6_+_30693464 0.471 NM_014046
MRPS18B
mitochondrial ribosomal protein S18B
chr14_+_23905984 0.469 NM_001136022
NM_001198967
NFATC4

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4

chr2_+_110013297 0.468 NM_033514
LIMS3-LOC440895
LIMS3
LIMS3-LOC440895 read-through
LIM and senescent cell antigen-like domains 3
chr17_-_20739924 0.467 NM_001004306
CCDC144NL
coiled-coil domain containing 144 family, N-terminal like
chr12_-_123568781 0.467


chr4_+_146238936 0.467 ABCE1
ATP-binding cassette, sub-family E (OABP), member 1
chr13_-_27967215 0.466 NM_001159920
NM_001160030
NM_001160031
NM_002019
FLT1



fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)



chr2_-_202353818 0.466


chr2_-_191723951 0.465 STAT4
signal transducer and activator of transcription 4
chr5_+_121675672 0.460 NM_005460
SNCAIP
synuclein, alpha interacting protein
chr16_+_18903009 0.460 NM_001160364
TMC7
transmembrane channel-like 7
chr14_+_99017485 0.459 NM_001099402
CCNK
cyclin K
chr14_-_49122813 0.458 NM_001030001
NM_001032
RPS29

ribosomal protein S29

chr6_+_39868116 0.458


chr12_-_47604930 0.458 NM_001143781
FKBP11
FK506 binding protein 11, 19 kDa
chr4_+_146238818 0.457 ABCE1
ATP-binding cassette, sub-family E (OABP), member 1
chr13_-_32010883 0.452 NM_014887
NM_033111
N4BP2L2

NEDD4 binding protein 2-like 2

chr2_+_131579355 0.452 PLEKHB2
pleckstrin homology domain containing, family B (evectins) member 2
chr2_+_190916571 0.451 INPP1
inositol polyphosphate-1-phosphatase
chr17_+_8093319 0.449 NM_012393
PFAS
phosphoribosylformylglycinamidine synthase
chr9_+_111582317 0.449 NM_053016
NM_007203
NM_147150
PALM2
PALM2-AKAP2

paralemmin 2
PALM2-AKAP2 readthrough

chr3_+_134775094 0.448 NM_001134422
NM_017548
CDV3

CDV3 homolog (mouse)

chr19_+_53814574 0.447 SPHK2
sphingosine kinase 2
chr17_+_37098652 0.447 NM_005801
EIF1
eukaryotic translation initiation factor 1
chr14_-_38971370 0.447 NM_203301
FBXO33
F-box protein 33
chr14_+_67156386 0.445 ARG2
arginase, type II
chr12_-_55013713 0.445 NM_001127460
PAN2
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr4_-_146238746 0.444 NM_014885
ANAPC10
anaphase promoting complex subunit 10
chr12_-_10657397 0.442 NM_018048
MAGOHB
mago-nashi homolog B (Drosophila)
chr4_-_44145580 0.442 NM_198353
KCTD8
potassium channel tetramerisation domain containing 8
chr17_-_46553083 0.441 NM_001130528
NM_003971
SPAG9

sperm associated antigen 9

chr11_-_103540275 0.440 PDGFD
platelet derived growth factor D
chr4_-_111777651 0.440 PITX2
paired-like homeodomain 2
chr17_+_37098667 0.439 EIF1
eukaryotic translation initiation factor 1
chr5_-_148911105 0.438 CSNK1A1
casein kinase 1, alpha 1
chr21_+_32706615 0.437 NM_058187
C21orf63
chromosome 21 open reading frame 63
chr3_-_151746589 0.436 SERP1
stress-associated endoplasmic reticulum protein 1
chr3_-_151963607 0.434 SIAH2
seven in absentia homolog 2 (Drosophila)
chr15_+_60146467 0.432 NM_207322
C2CD4A
C2 calcium-dependent domain containing 4A
chr5_-_59100194 0.431 NM_001197218
PDE4D
phosphodiesterase 4D, cAMP-specific

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.37 2.20e-16 GO:0044260 cellular macromolecule metabolic process
1.30 5.69e-12 GO:0043170 macromolecule metabolic process
1.13 1.63e-10 GO:0009987 cellular process
1.24 2.09e-10 GO:0044237 cellular metabolic process
1.52 3.06e-10 GO:0010467 gene expression
1.52 5.18e-09 GO:0009059 macromolecule biosynthetic process
1.52 7.08e-09 GO:0034645 cellular macromolecule biosynthetic process
1.50 1.40e-08 GO:0016070 RNA metabolic process
1.43 1.79e-08 GO:0090304 nucleic acid metabolic process
1.31 7.74e-08 GO:0031323 regulation of cellular metabolic process
1.37 1.36e-07 GO:0031326 regulation of cellular biosynthetic process
1.56 2.26e-07 GO:0051641 cellular localization
1.36 2.50e-07 GO:0009889 regulation of biosynthetic process
1.38 5.30e-07 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.58 8.94e-07 GO:0051649 establishment of localization in cell
1.35 9.38e-07 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.30 9.81e-07 GO:0080090 regulation of primary metabolic process
1.19 1.19e-06 GO:0044238 primary metabolic process
1.36 1.47e-06 GO:0010556 regulation of macromolecule biosynthetic process
1.31 1.80e-06 GO:0034641 cellular nitrogen compound metabolic process
1.30 1.96e-06 GO:0006807 nitrogen compound metabolic process
1.30 2.16e-06 GO:0060255 regulation of macromolecule metabolic process
1.34 2.72e-06 GO:0051171 regulation of nitrogen compound metabolic process
1.26 5.06e-06 GO:0019222 regulation of metabolic process
1.67 6.03e-06 GO:0046907 intracellular transport
1.36 1.24e-05 GO:0051252 regulation of RNA metabolic process
1.34 1.27e-05 GO:0044267 cellular protein metabolic process
1.32 1.84e-05 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.34 2.03e-05 GO:0044249 cellular biosynthetic process
1.33 2.11e-05 GO:0010468 regulation of gene expression
1.16 5.46e-05 GO:0008152 metabolic process
1.44 7.32e-05 GO:0007399 nervous system development
1.32 1.02e-04 GO:0009058 biosynthetic process
1.58 1.06e-04 GO:0006351 transcription, DNA-dependent
1.35 1.09e-04 GO:0006355 regulation of transcription, DNA-dependent
1.16 2.09e-04 GO:0050794 regulation of cellular process
1.51 8.29e-04 GO:0032774 RNA biosynthetic process
1.54 8.32e-04 GO:0045184 establishment of protein localization
1.14 8.59e-04 GO:0050789 regulation of biological process
1.50 1.17e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.97 1.81e-03 GO:0002755 MyD88-dependent toll-like receptor signaling pathway
1.52 2.51e-03 GO:0015031 protein transport
1.29 2.98e-03 GO:0048522 positive regulation of cellular process
1.13 3.25e-03 GO:0065007 biological regulation
1.22 4.26e-03 GO:0032502 developmental process
1.26 6.76e-03 GO:0048518 positive regulation of biological process
1.44 7.16e-03 GO:0008104 protein localization
1.22 8.92e-03 GO:0071840 cellular component organization or biogenesis
1.38 9.40e-03 GO:0033036 macromolecule localization
2.88 9.44e-03 GO:0034130 toll-like receptor 1 signaling pathway
2.88 9.44e-03 GO:0034134 toll-like receptor 2 signaling pathway
1.57 1.02e-02 GO:0006396 RNA processing
1.54 1.24e-02 GO:0030182 neuron differentiation
1.25 1.29e-02 GO:0071841 cellular component organization or biogenesis at cellular level
1.22 1.44e-02 GO:0007275 multicellular organismal development
1.23 1.86e-02 GO:0048856 anatomical structure development
1.23 1.88e-02 GO:0019538 protein metabolic process
1.28 2.86e-02 GO:0048869 cellular developmental process
1.44 3.42e-02 GO:0022008 neurogenesis
1.28 3.44e-02 GO:0030154 cell differentiation
2.55 3.63e-02 GO:0002224 toll-like receptor signaling pathway
1.21 3.63e-02 GO:0016043 cellular component organization
1.24 4.88e-02 GO:0071842 cellular component organization at cellular level

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.21 2.87e-18 GO:0043227 membrane-bounded organelle
1.15 4.00e-18 GO:0044424 intracellular part
1.21 7.26e-18 GO:0043231 intracellular membrane-bounded organelle
1.15 9.69e-18 GO:0005622 intracellular
1.19 1.28e-17 GO:0043226 organelle
1.19 2.30e-17 GO:0043229 intracellular organelle
1.27 1.52e-12 GO:0005634 nucleus
1.26 2.00e-12 GO:0044422 organelle part
1.26 7.05e-12 GO:0044446 intracellular organelle part
1.18 1.22e-10 GO:0005737 cytoplasm
1.42 7.91e-09 GO:0044428 nuclear part
1.42 3.10e-07 GO:0031981 nuclear lumen
1.20 3.76e-07 GO:0044444 cytoplasmic part
1.36 9.37e-07 GO:0070013 intracellular organelle lumen
1.35 1.62e-06 GO:0043233 organelle lumen
1.27 1.67e-06 GO:0032991 macromolecular complex
1.35 1.93e-06 GO:0031974 membrane-enclosed lumen
1.29 1.14e-05 GO:0043234 protein complex
1.42 1.62e-04 GO:0005654 nucleoplasm
1.29 1.93e-03 GO:0005829 cytosol
1.51 4.22e-03 GO:0015630 microtubule cytoskeleton
2.90 1.78e-02 GO:0005793 ER-Golgi intermediate compartment
1.46 1.84e-02 GO:0044451 nucleoplasm part
1.35 4.20e-02 GO:0005783 endoplasmic reticulum
1.28 4.25e-02 GO:0012505 endomembrane system
1.36 4.49e-02 GO:0005794 Golgi apparatus

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.20 5.89e-11 GO:0005515 protein binding
1.10 1.73e-08 GO:0005488 binding
1.59 8.73e-07 GO:0001071 nucleic acid binding transcription factor activity
1.59 8.73e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.63 2.21e-06 GO:0003723 RNA binding
1.27 1.76e-05 GO:0003676 nucleic acid binding
1.33 1.82e-05 GO:0000166 nucleotide binding
1.59 2.82e-04 GO:0043565 sequence-specific DNA binding
1.45 1.02e-03 GO:0030528 transcription regulator activity
1.31 1.19e-03 GO:0017076 purine nucleotide binding
1.32 1.23e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.31 1.55e-03 GO:0032553 ribonucleotide binding
1.31 1.55e-03 GO:0032555 purine ribonucleotide binding
1.32 7.53e-03 GO:0030554 adenyl nucleotide binding
1.33 8.14e-03 GO:0005524 ATP binding
1.32 1.08e-02 GO:0032559 adenyl ribonucleotide binding