Motif ID: CDC5L.p2

Z-value: 1.731


Transcription factors associated with CDC5L.p2:

Gene SymbolEntrez IDGene Name
CDC5L 988 CDC5 cell division cycle 5-like (S. pombe)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CDC5Lchr6_+_44463418-0.146.0e-01Click!


Activity profile for motif CDC5L.p2.

activity profile for motif CDC5L.p2


Sorted Z-values histogram for motif CDC5L.p2

Sorted Z-values for motif CDC5L.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CDC5L.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_38772870 2.504 NM_054024
MIA2
melanoma inhibitory activity 2
chr18_+_59593591 2.468 NM_003784
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr2_+_165804157 2.359 NM_001040142
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr11_+_110631916 2.065 NM_198498
C11orf53
chromosome 11 open reading frame 53
chr5_+_147423727 1.975 NM_001127698
NM_001127699
NM_006846
SPINK5


serine peptidase inhibitor, Kazal type 5


chr11_-_83706027 1.946 DLG2
discs, large homolog 2 (Drosophila)
chr1_+_50344550 1.929 NM_001144775
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr3_+_73193499 1.904 NM_018029
EBLN2
endogenous Borna-like N element-2
chr5_+_140568451 1.903 NM_018932
PCDHB12
protocadherin beta 12
chr18_-_29882555 1.820 NM_001198549
NOL4
nucleolar protein 4
chr15_+_47502666 1.784 NM_002009
FGF7
fibroblast growth factor 7
chr1_-_150328153 1.645 NM_001008536
TCHHL1
trichohyalin-like 1
chr9_+_104797413 1.608 NM_001340
CYLC2
cylicin, basic protein of sperm head cytoskeleton 2
chr4_+_47403107 1.595


chr20_-_39362122 1.595 NM_015035
ZHX3
zinc fingers and homeoboxes 3
chr18_-_39111243 1.594 NM_020783
SYT4
synaptotagmin IV
chr12_+_54080480 1.591 NM_001005518
OR6C65
olfactory receptor, family 6, subfamily C, member 65
chr4_-_68432293 1.589 NM_004262
TMPRSS11D
transmembrane protease, serine 11D
chr6_+_55147029 1.568 NM_001526
HCRTR2
hypocretin (orexin) receptor 2
chr4_-_186537145 1.547 NM_018409
LRP2BP
LRP2 binding protein
chr19_+_16691786 1.499 NM_001007525
NWD1
NACHT and WD repeat domain containing 1
chr13_-_109600709 1.494 COL4A1
collagen, type IV, alpha 1
chr6_-_155818728 1.490 NM_015718
NOX3
NADPH oxidase 3
chr4_+_128773529 1.476 NM_015693
INTU
inturned planar cell polarity effector homolog (Drosophila)
chr12_-_10433852 1.470 NM_007360
KLRK1
killer cell lectin-like receptor subfamily K, member 1
chrX_-_15593074 1.454 NM_020665
TMEM27
transmembrane protein 27
chr5_+_148711419 1.429 GRPEL2
GrpE-like 2, mitochondrial (E. coli)
chr11_+_27019084 1.419 NM_003986
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr4_-_68793928 1.345 NM_182502
TMPRSS11B
transmembrane protease, serine 11B
chr4_-_152368492 1.289 SH3D19
SH3 domain containing 19
chr2_+_211166323 1.286 NM_001122634
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr11_-_13474101 1.274 NM_000315
PTH
parathyroid hormone
chr7_-_113346284 1.253 NM_002711
PPP1R3A
protein phosphatase 1, regulatory (inhibitor) subunit 3A
chr6_+_127940011 1.242 NM_001010905
C6orf58
chromosome 6 open reading frame 58
chr18_+_59705918 1.234 NM_001143818
NM_002575
SERPINB2

serpin peptidase inhibitor, clade B (ovalbumin), member 2

chr4_+_69465107 1.221 NM_014058
TMPRSS11E
transmembrane protease, serine 11E
chr1_+_156716290 1.220 NM_001004472
OR10R2
olfactory receptor, family 10, subfamily R, member 2
chr12_-_15706340 1.203 EPS8
epidermal growth factor receptor pathway substrate 8
chr3_+_142175329 1.192 SLC25A36
solute carrier family 25, member 36
chr1_+_227506751 1.157 NM_006542
SPHAR
S-phase response (cyclin related)
chr1_+_239762179 1.146 NM_003679
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr5_+_128468785 1.134 ISOC1
isochorismatase domain containing 1
chr20_-_33706532 1.107 RBM12
RNA binding motif protein 12
chr3_+_103636548 1.106 NM_175056
ZPLD1
zona pellucida-like domain containing 1
chr18_-_49944986 1.088 MBD2
methyl-CpG binding domain protein 2
chrX_-_117003310 1.066 NM_001168299
KLHL13
kelch-like 13 (Drosophila)
chr4_-_38482805 1.066 NM_003263
TLR1
toll-like receptor 1
chr16_+_14201687 1.065 MKL2
MKL/myocardin-like 2
chr5_+_147628567 1.061 NM_001040129
SPINK13
serine peptidase inhibitor, Kazal type 13 (putative)
chr3_+_173043832 1.022 NM_001164436
TMEM212
transmembrane protein 212
chr9_+_109131814 1.016 RAD23B
RAD23 homolog B (S. cerevisiae)
chr7_+_123083096 1.012 NM_207163
LMOD2
leiomodin 2 (cardiac)
chr12_-_21379098 1.011 NM_021094
SLCO1A2
solute carrier organic anion transporter family, member 1A2
chr4_+_109763119 1.003 RPL34
ribosomal protein L34
chr11_+_89296879 0.999 NM_001105522
TRIM49L1
tripartite motif containing 49-like 1
chr1_+_200698493 0.979 NM_032103
NM_032104
PPP1R12B

protein phosphatase 1, regulatory (inhibitor) subunit 12B

chr13_-_85271329 0.971 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr2_-_61566477 0.969 XPO1
exportin 1 (CRM1 homolog, yeast)
chr12_-_74010071 0.956 NM_032606
CAPS2
calcyphosine 2
chr3_+_99484421 0.936 NM_001005482
OR5H2
olfactory receptor, family 5, subfamily H, member 2
chr10_-_93992982 0.930 NM_001178137
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr20_+_43691797 0.929 NM_080753
WFDC10A
WAP four-disulfide core domain 10A
chr5_-_137876416 0.924 ETF1
eukaryotic translation termination factor 1
chr18_+_50409387 0.917 NM_173629
C18orf26
chromosome 18 open reading frame 26
chr5_+_147775652 0.915 FBXO38
F-box protein 38
chr6_-_133008834 0.904 NM_138327
TAAR1
trace amine associated receptor 1
chr21_-_30774502 0.895 NM_181607
KRTAP19-1
keratin associated protein 19-1
chr14_-_22947320 0.887 NM_002471
MYH6
myosin, heavy chain 6, cardiac muscle, alpha
chr6_-_49789204 0.880 NM_001142407
NM_001142408
NM_001142417
NM_001142435
NM_003296
CRISP2




cysteine-rich secretory protein 2




chr11_-_55757236 0.857 NM_001004746
OR5T2
olfactory receptor, family 5, subfamily T, member 2
chr2_-_210888010 0.845 NM_079420
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr10_-_97190885 0.845 NM_001034954
NM_001034955
NM_001034956
NM_001034957
NM_006434
SORBS1




sorbin and SH3 domain containing 1




chr2_+_228386800 0.840 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr2_-_180319013 0.838 NM_001113397
ZNF385B
zinc finger protein 385B
chr3_-_95230143 0.829 NM_001001850
STX19
syntaxin 19
chr1_-_152431175 0.824 NM_152263
TPM3
tropomyosin 3
chr4_-_184478920 0.819 NM_001111319
CLDN22
claudin 22
chr13_+_31211678 0.806 NM_001166058
NM_130806
RXFP2

relaxin/insulin-like family peptide receptor 2

chr2_-_162717159 0.806 NM_002054
GCG
glucagon
chr5_-_125956996 0.788 ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr10_+_126620681 0.786 NM_017580
ZRANB1
zinc finger, RAN-binding domain containing 1
chr10_+_96688399 0.777 NM_000771
CYP2C9
cytochrome P450, family 2, subfamily C, polypeptide 9
chr20_-_44494961 0.775 ELMO2
engulfment and cell motility 2
chr10_+_90511142 0.773 NM_001102469
LIPN
lipase, family member N
chr13_-_37070862 0.768 NM_001135934
NM_001135935
NM_001135936
NM_006475
POSTN



periostin, osteoblast specific factor



chr19_-_21438525 0.765


chr1_+_151240846 0.765 NM_001097589
NM_005416
SPRR3

small proline-rich protein 3

chr11_-_92570693 0.765 NM_152313
SLC36A4
solute carrier family 36 (proton/amino acid symporter), member 4
chr4_-_38534802 0.763 NM_006068
TLR6
toll-like receptor 6
chr4_-_80548378 0.756 NM_033214
GK2
glycerol kinase 2
chr1_+_184532027 0.754 NM_001127708
NM_001127709
NM_001127710
NM_005807
PRG4



proteoglycan 4



chr14_+_59934178 0.750


chr10_+_90414125 0.747 NM_001198828
NM_001198829
NM_001198830
NM_004190
LIPF



lipase, gastric



chr6_-_112001590 0.747 NM_001164282
TRAF3IP2
TRAF3 interacting protein 2
chr19_-_10558906 0.744 NM_005498
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr4_+_53986759 0.742 FIP1L1
FIP1 like 1 (S. cerevisiae)
chr12_+_21417068 0.740 NM_000415
IAPP
islet amyloid polypeptide
chr12_+_53534565 0.739 NM_058173
MUCL1
mucin-like 1
chr2_+_151922350 0.738 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr12_-_119733062 0.735 SPPL3
signal peptide peptidase 3
chr12_+_10222823 0.735 NM_153022
C12orf59
chromosome 12 open reading frame 59
chr2_+_165858586 0.730 NM_021007
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr4_+_109033868 0.723 NM_001136257
NM_152621
SGMS2

sphingomyelin synthase 2

chr11_+_33306652 0.721 HIPK3
homeodomain interacting protein kinase 3
chr1_-_89364273 0.719 NM_004120
GBP2
guanylate binding protein 2, interferon-inducible
chr16_+_68238460 0.719 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr5_+_161210280 0.710 NM_001127648
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr4_+_73123712 0.710 NM_001144756
NM_053036
NPFFR2

neuropeptide FF receptor 2

chr3_-_110155237 0.709 NM_005459
GUCA1C
guanylate cyclase activator 1C
chr5_-_132228375 0.705 NM_005260
GDF9
growth differentiation factor 9
chr12_+_100512877 0.700 NM_002465
NM_206819
NM_206820
NM_206821
MYBPC1



myosin binding protein C, slow type



chr2_-_21106291 0.696 APOB
apolipoprotein B (including Ag(x) antigen)
chr9_-_94338072 0.689 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chrX_+_110252960 0.683 NM_001128168
NM_001128172
NM_001128173
PAK3


p21 protein (Cdc42/Rac)-activated kinase 3


chr5_+_140160966 0.676 NM_018906
NM_031497
PCDHA3

protocadherin alpha 3

chr11_+_54786233 0.668 NM_024114
TRIM48
tripartite motif containing 48
chr7_+_50106227 0.662 NM_001161834
C7orf72
chromosome 7 open reading frame 72
chr4_+_70831387 0.661 NM_001025104
NM_001890
CSN1S1

casein alpha s1

chr2_-_215711313 0.655 NM_173076
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr3_-_152541129 0.652 NM_176876
P2RY12
purinergic receptor P2Y, G-protein coupled, 12
chrX_-_19598912 0.650 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr12_+_77963563 0.650 NM_001135806
SYT1
synaptotagmin I
chr21_-_30796278 0.650 NM_181611
KRTAP19-5
keratin associated protein 19-5
chr6_-_132980901 0.639 NM_014626
TAAR2
trace amine associated receptor 2
chr2_+_61243132 0.639 NM_001143959
C2orf74
chromosome 2 open reading frame 74
chr4_+_113437947 0.633 NM_001102406
NM_025144
ALPK1

alpha-kinase 1

chr17_-_36451189 0.632 NM_030967
KRTAP1-3
KRTAP1-1
keratin associated protein 1-3
keratin associated protein 1-1
chr10_-_62163083 0.632 ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr1_+_169747788 0.631 PRRC2C
proline-rich coiled-coil 2C
chr4_+_38740246 0.630 NM_015990
NM_199039
KLHL5

kelch-like 5 (Drosophila)

chr3_+_63859114 0.625 NM_001177387
ATXN7
ataxin 7
chr1_+_19807168 0.620


chr1_-_196776697 0.619 NM_133262
NM_133326
ATP6V1G3

ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3

chr3_+_191588354 0.612 NM_006580
CLDN16
claudin 16
chr2_-_171796069 0.612 NM_001136554
TLK1
tousled-like kinase 1
chr15_-_74941339 0.611 NM_001145923
SCAPER
S-phase cyclin A-associated protein in the ER
chr12_+_91620749 0.611 NM_001037671
NM_001178097
C12orf74

chromosome 12 open reading frame 74

chr10_-_62002672 0.600 ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr11_-_123130435 0.597 NM_001005188
OR6X1
olfactory receptor, family 6, subfamily X, member 1
chr1_+_24713396 0.597 RCAN3
RCAN family member 3
chr12_-_9123126 0.594 A2M
alpha-2-macroglobulin
chr12_-_13139848 0.594 NM_031289
NM_153823
GSG1

germ cell associated 1

chr4_+_141484046 0.587 NM_001153446
NM_001153635
NM_001153585
NM_001153690
SCOC



short coiled-coil protein



chr2_+_183697327 0.580 NM_138285
NUP35
nucleoporin 35kDa
chr13_+_51496679 0.578 NM_021645
ALG11
UTP14C
asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (yeast)
UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
chr18_+_30589937 0.576 NM_001390
NM_001391
DTNA

dystrobrevin, alpha

chr11_-_128242342 0.574 NM_153764
NM_153765
NM_153766
NM_153767
KCNJ1



potassium inwardly-rectifying channel, subfamily J, member 1



chr17_+_73511843 0.573 NM_001142640
NM_018996
TNRC6C

trinucleotide repeat containing 6C

chr4_+_1375339 0.572 NM_175918
CRIPAK
cysteine-rich PAK1 inhibitor
chr5_+_140494971 0.571 NM_015669
PCDHB5
protocadherin beta 5
chr17_+_43263991 0.569 NM_033413
LRRC46
leucine rich repeat containing 46
chr3_+_123526700 0.569 NM_005213
CSTA
cystatin A (stefin A)
chr14_-_19871267 0.569 NM_021178
NM_182849
CCNB1IP1

cyclin B1 interacting protein 1, E3 ubiquitin protein ligase

chr7_-_84589182 0.562 NM_152754
SEMA3D
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr2_+_119416214 0.556 NM_006770
MARCO
macrophage receptor with collagenous structure
chr11_-_83661878 0.552 NM_001142700
DLG2
discs, large homolog 2 (Drosophila)
chr5_+_156540425 0.547 NM_005546
ITK
IL2-inducible T-cell kinase
chr12_-_9804682 0.547 NM_001781
CD69
CD69 molecule
chr4_-_153493133 0.546 NM_018315
FBXW7
F-box and WD repeat domain containing 7
chr1_-_143708467 0.540 NM_001195260
PDE4DIP
phosphodiesterase 4D interacting protein
chr3_+_51837608 0.540 NM_001085479
IQCF3
IQ motif containing F3
chr12_-_21818881 0.540 NM_004982
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
chr17_-_2913650 0.537 NM_014566
OR1D4
OR1D5
olfactory receptor, family 1, subfamily D, member 4 (gene/pseudogene)
olfactory receptor, family 1, subfamily D, member 5
chr20_+_2224612 0.537 NM_003245
TGM3
transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase)
chr14_-_49543987 0.534 NM_001012706
C14orf182
chromosome 14 open reading frame 182
chr10_+_49279647 0.533 NM_002750
NM_139046
NM_139047
NM_139049
MAPK8



mitogen-activated protein kinase 8



chrX_+_26066380 0.530 NM_173699
MAGEB18
melanoma antigen family B, 18
chr3_-_113701073 0.530 NM_001085357
NM_181780
BTLA

B and T lymphocyte associated

chr5_-_131907071 0.527 NM_000879
IL5
interleukin 5 (colony-stimulating factor, eosinophil)
chrX_-_131089552 0.527 NM_194277
FRMD7
FERM domain containing 7
chr2_+_162189090 0.526 NM_001178015
NM_001178016
NM_022058
SLC4A10


solute carrier family 4, sodium bicarbonate transporter, member 10


chr13_+_47948586 0.525 RB1
retinoblastoma 1
chr2_+_143351695 0.524 KYNU
kynureninase
chr11_-_1586190 0.523 NM_001012708
KRTAP5-3
keratin associated protein 5-3
chr21_-_35174742 0.523 RUNX1
runt-related transcription factor 1
chr1_+_10432362 0.517 NM_001302
CORT
cortistatin
chr22_+_40372957 0.516 XRCC6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr6_-_46155937 0.516 NM_001114086
CLIC5
chloride intracellular channel 5
chr7_+_142590633 0.515 NM_176881
TAS2R39
taste receptor, type 2, member 39
chr11_-_102156531 0.515 NM_002425
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr3_+_142525744 0.508 NM_001080412
ZBTB38
zinc finger and BTB domain containing 38
chr18_-_35634247 0.505 LOC647946
hypothetical LOC647946
chr4_-_177427252 0.498 NM_080874
ASB5
ankyrin repeat and SOCS box containing 5
chr3_-_47073910 0.495 SETD2
SET domain containing 2
chr1_+_103898844 0.495 NM_020978
AMY2B
amylase, alpha 2B (pancreatic)
chr16_+_52037186 0.493 RBL2
retinoblastoma-like 2 (p130)
chr12_-_44919818 0.491 SLC38A1
solute carrier family 38, member 1
chr11_+_85036610 0.484 NM_032273
TMEM126A
transmembrane protein 126A
chr7_+_94135384 0.478 PEG10
paternally expressed 10
chr9_-_21340885 0.476 NM_021002
IFNA6
interferon, alpha 6
chrX_+_105823723 0.474 NM_024539
RNF128
ring finger protein 128
chr1_-_42549347 0.474


chr1_-_45868775 0.471 GPBP1L1
GC-rich promoter binding protein 1-like 1
chr2_-_160764819 0.468 NM_000888
ITGB6
integrin, beta 6
chr6_-_119137923 0.465 NM_001178035
C6orf204
chromosome 6 open reading frame 204
chr14_+_61532293 0.461 NM_031914
SYT16
synaptotagmin XVI
chr22_-_14829803 0.460 NM_001005239
OR11H1
olfactory receptor, family 11, subfamily H, member 1
chr11_+_111551417 0.459 NM_031938
BCO2
beta-carotene oxygenase 2
chr9_+_674193 0.453


chrX_+_37777730 0.449 NM_001163334
SYTL5
synaptotagmin-like 5

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.53 1.97e-05 GO:0007608 sensory perception of smell
2.36 7.76e-05 GO:0007606 sensory perception of chemical stimulus
1.91 6.06e-04 GO:0007600 sensory perception
1.27 5.61e-03 GO:0032501 multicellular organismal process
1.53 8.07e-03 GO:0003008 system process
7.32 4.81e-02 GO:0031069 hair follicle morphogenesis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.34 6.06e-05 GO:0071944 cell periphery
1.31 7.85e-04 GO:0005886 plasma membrane
1.48 8.07e-04 GO:0005576 extracellular region
1.23 6.49e-03 GO:0016021 integral to membrane
1.22 1.59e-02 GO:0031224 intrinsic to membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.53 9.49e-06 GO:0004984 olfactory receptor activity
1.79 2.10e-03 GO:0004930 G-protein coupled receptor activity
1.55 1.73e-02 GO:0004888 transmembrane receptor activity
3.50 1.80e-02 GO:0004867 serine-type endopeptidase inhibitor activity