Motif ID: CRX.p2

Z-value: 1.984


Transcription factors associated with CRX.p2:

Gene SymbolEntrez IDGene Name
CRX 1406 cone-rod homeobox

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CRXchr19_+_530169100.185.0e-01Click!


Activity profile for motif CRX.p2.

activity profile for motif CRX.p2


Sorted Z-values histogram for motif CRX.p2

Sorted Z-values for motif CRX.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CRX.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_134290789 2.878


chr20_-_48165886 2.047 NM_022442
NM_021988
NM_199144
UBE2V1


ubiquitin-conjugating enzyme E2 variant 1


chr4_+_110968594 1.763 NM_006583
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr11_-_57964221 1.742 NM_001004733
OR5B12
olfactory receptor, family 5, subfamily B, member 12
chr11_-_57947358 1.644 NM_001005566
OR5B2
olfactory receptor, family 5, subfamily B, member 2
chr9_+_115678365 1.617 NM_133374
ZNF618
zinc finger protein 618
chr21_-_39737997 1.543 NM_152505
LCA5L
Leber congenital amaurosis 5-like
chr8_-_81155564 1.519 NM_001025252
TPD52
tumor protein D52
chr22_+_48927610 1.439 NM_001164106
MOV10L1
Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse)
chr3_-_47073910 1.366 SETD2
SET domain containing 2
chr1_+_559129 1.308


chr1_-_246045653 1.283 NM_001001966
OR14A16
olfactory receptor, family 14, subfamily A, member 16
chr18_+_53865455 1.245 NM_001144964
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr1_-_166779825 1.220 NM_003175
XCL1
XCL2
chemokine (C motif) ligand 1
chemokine (C motif) ligand 2
chr11_-_62668268 1.200 NM_001136506
SLC22A24
solute carrier family 22, member 24
chr2_-_180580024 1.193 NM_020943
CWC22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr16_-_20246309 1.183 NM_001007240
NM_001007241
NM_001007242
NM_001502
GP2



glycoprotein 2 (zymogen granule membrane)



chr1_+_116744992 1.183 ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr9_+_134884627 1.169 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr1_+_20269239 1.111 NM_000929
PLA2G5
phospholipase A2, group V
chr15_-_88023576 1.076 NM_001145311
NM_002666
PLIN1

perilipin 1

chr16_+_56567839 1.065 NM_199046
NM_199456
TEPP

testis, prostate and placenta expressed

chr1_-_171441234 1.061 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chrX_-_11194015 1.050 NM_013423
ARHGAP6
Rho GTPase activating protein 6
chr1_+_205344200 1.028 NM_000715
C4BPA
complement component 4 binding protein, alpha
chr17_-_36587965 1.009 NM_033062
KRTAP4-2
keratin associated protein 4-2
chr13_+_38159172 1.008 NM_207361
FREM2
FRAS1 related extracellular matrix protein 2
chr1_+_154573728 1.006 NM_144627
C1orf182
chromosome 1 open reading frame 182
chr20_-_33706532 0.982 RBM12
RNA binding motif protein 12
chr3_+_161877640 0.979 NM_025047
ARL14
ADP-ribosylation factor-like 14
chr17_+_38306339 0.972 NM_000151
G6PC
glucose-6-phosphatase, catalytic subunit
chr3_-_19950675 0.961 NM_144715
EFHB
EF-hand domain family, member B
chr1_+_151209751 0.957 NM_173080
SPRR4
small proline-rich protein 4
chr20_-_43693320 0.949 NM_147198
WFDC9
WAP four-disulfide core domain 9
chr11_+_55319607 0.945 NM_001004735
OR5D14
olfactory receptor, family 5, subfamily D, member 14
chr16_-_46823682 0.930 NM_033151
ABCC11
ATP-binding cassette, sub-family C (CFTR/MRP), member 11
chr22_+_21370394 0.913 IGL@
immunoglobulin lambda locus
chr15_-_75364387 0.902 NM_024776
PEAK1
NKF3 kinase family member
chr8_-_82522175 0.895 NM_002677
PMP2
peripheral myelin protein 2
chr22_+_21094094 0.895


chr2_+_151922350 0.877 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr12_+_10015274 0.856 NM_138337
NM_201623
CLEC12A

C-type lectin domain family 12, member A

chrX_+_69371229 0.856 NM_001013579
AWAT1
acyl-CoA wax alcohol acyltransferase 1
chrX_+_55666557 0.856 NM_198451
FOXR2
forkhead box R2
chr2_+_165804157 0.855 NM_001040142
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr10_-_116408046 0.851 NM_002313
ABLIM1
actin binding LIM protein 1
chr7_+_29486010 0.849 NM_001039936
CHN2
chimerin (chimaerin) 2
chr9_-_99740243 0.840 NM_197978
HEMGN
hemogen
chr6_-_42798286 0.838 NM_000322
PRPH2
peripherin 2 (retinal degeneration, slow)
chr12_-_10453409 0.837 NM_013431
KLRC4-KLRK1
KLRC4
KLRC4-KLRK1 read-through transcript
killer cell lectin-like receptor subfamily C, member 4
chr20_-_55368284 0.821 NM_001190472
MTRNR2L3
MT-RNR2-like 3
chr7_-_33047042 0.818 NM_001166118
NM_016489
NT5C3

5'-nucleotidase, cytosolic III

chr7_+_111850367 0.817 NM_001007245
NM_001197080
IFRD1

interferon-related developmental regulator 1

chr9_+_4829763 0.813 RCL1
RNA terminal phosphate cyclase-like 1
chr5_+_161045235 0.800 NM_000811
GABRA6
gamma-aminobutyric acid (GABA) A receptor, alpha 6
chr10_-_85991177 0.796 NM_015613
LRIT1
leucine-rich repeat, immunoglobulin-like and transmembrane domains 1
chr6_+_163904564 0.793 QKI
quaking homolog, KH domain RNA binding (mouse)
chr8_-_95289945 0.787 NM_004063
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr21_-_35174742 0.787 RUNX1
runt-related transcription factor 1
chr13_-_23369124 0.786 NM_001007537
C1QTNF9B
C1q and tumor necrosis factor related protein 9B
chr1_-_239865724 0.785 NM_001821
CHML
choroideremia-like (Rab escort protein 2)
chr6_-_66473790 0.781 NM_001142800
NM_001142801
EYS

eyes shut homolog (Drosophila)

chr3_+_23904086 0.777 UBE2E1
ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)
chr5_+_140454382 0.776 NM_018936
PCDHB2
protocadherin beta 2
chr2_-_55090759 0.772 NM_007008
RTN4
reticulon 4
chr3_+_99484421 0.766 NM_001005482
OR5H2
olfactory receptor, family 5, subfamily H, member 2
chr5_-_36027100 0.765 NM_152404
UGT3A1
UDP glycosyltransferase 3 family, polypeptide A1
chr21_+_37377116 0.761 NM_003316
TTC3
tetratricopeptide repeat domain 3
chr12_+_54611212 0.761 NM_001345
DGKA
diacylglycerol kinase, alpha 80kDa
chr1_+_159032551 0.757 NM_001033667
NM_002348
LY9

lymphocyte antigen 9

chr7_+_128367961 0.757 NM_001098627
IRF5
interferon regulatory factor 5
chr18_+_28023984 0.755 NM_005925
MEP1B
meprin A, beta
chr10_+_91077581 0.753 NM_001549
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr1_-_12831164 0.750 NM_001013631
HNRNPCL1
heterogeneous nuclear ribonucleoprotein C-like 1
chr9_+_122923864 0.737 CEP110
centrosomal protein 110kDa
chr12_+_102505180 0.736 NM_017564
STAB2
stabilin 2
chr2_-_158008763 0.734 NM_004288
CYTIP
cytohesin 1 interacting protein
chr1_+_227506751 0.734 NM_006542
SPHAR
S-phase response (cyclin related)
chr3_-_194579207 0.726 NM_198505
ATP13A5
ATPase type 13A5
chr1_+_202033273 0.726 NM_001174108
ZBED6
zinc finger, BED-type containing 6
chr6_+_54281161 0.723 NM_014464
TINAG
tubulointerstitial nephritis antigen
chr18_+_50049846 0.713 NM_007195
POLI
polymerase (DNA directed) iota
chr19_+_43616167 0.710 NM_000540
NM_001042723
RYR1

ryanodine receptor 1 (skeletal)

chr5_+_70980724 0.706 MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr11_+_93394025 0.705 NM_001098672
HEPHL1
hephaestin-like 1
chr17_+_33867169 0.701 NM_020876
ARHGAP23
Rho GTPase activating protein 23
chr11_-_113935789 0.701 NM_152315
FAM55A
family with sequence similarity 55, member A
chr17_+_31195760 0.698 TAF15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
chr5_+_140235114 0.697 NM_018903
NM_031864
PCDHA12

protocadherin alpha 12

chr6_+_125346208 0.695 NM_152553
RNF217
ring finger protein 217
chr2_+_114935623 0.695 NM_001178036
DPP10
dipeptidyl-peptidase 10 (non-functional)
chr5_-_22248630 0.691 CDH12
cadherin 12, type 2 (N-cadherin 2)
chr11_-_55460451 0.688 NM_006637
OR5I1
olfactory receptor, family 5, subfamily I, member 1
chr7_+_156677777 0.685


chr1_+_559618 0.684


chr1_+_74971423 0.675 NM_001162916
NM_138467
TYW3

tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)

chr8_-_18710575 0.674 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chr9_+_78283076 0.670 NM_001097635
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr1_+_166812466 0.670 NM_002995
XCL1
chemokine (C motif) ligand 1
chr11_-_35235325 0.667 SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr1_+_114323552 0.667 NM_020190
OLFML3
olfactomedin-like 3
chr2_-_215711313 0.664 NM_173076
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr6_-_132980901 0.663 NM_014626
TAAR2
trace amine associated receptor 2
chr3_+_140545528 0.657 NM_020191
MRPS22
mitochondrial ribosomal protein S22
chr2_-_65013070 0.654 LOC400958
hypothetical LOC400958
chr10_-_62431203 0.651 RHOBTB1
Rho-related BTB domain containing 1
chr7_-_50103335 0.650 NM_001159878
NM_007009
ZPBP

zona pellucida binding protein

chr12_+_54316910 0.650 NM_206899
OR10P1
olfactory receptor, family 10, subfamily P, member 1
chr2_+_191009265 0.646 MFSD6
major facilitator superfamily domain containing 6
chr7_+_93373755 0.645 NM_021955
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr6_+_32515596 0.636 NM_019111
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr10_-_82039158 0.636 NM_000429
MAT1A
methionine adenosyltransferase I, alpha
chr9_-_74757735 0.636 NM_000689
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr19_-_13910167 0.635 NM_024825
PODNL1
podocan-like 1
chr2_-_188021117 0.628 NM_005795
CALCRL
calcitonin receptor-like
chr12_+_54172413 0.626 NM_001005519
OR6C68
olfactory receptor, family 6, subfamily C, member 68
chr16_+_22432344 0.626 NM_001135865
LOC100132247
NPIPL3
nuclear pore complex interacting protein related gene
nuclear pore complex interacting protein-like 3
chr11_+_61473931 0.623 NM_001139443
NM_004183
BEST1

bestrophin 1

chr7_-_128203079 0.620 NM_001708
OPN1SW
opsin 1 (cone pigments), short-wave-sensitive
chr1_+_144149794 0.617 NM_006472
TXNIP
thioredoxin interacting protein
chr1_-_45868775 0.616 GPBP1L1
GC-rich promoter binding protein 1-like 1
chr8_-_7207899 0.615 NM_001164457
ZNF705G
zinc finger protein 705G
chr3_-_48344834 0.614 NM_001080525
SPINK8
serine peptidase inhibitor, Kazal type 8 (putative)
chr11_+_69176391 0.611 CCND1
cyclin D1
chr11_+_43622348 0.611


chr10_+_95838801 0.609 NM_001165979
PLCE1
phospholipase C, epsilon 1
chr9_-_35860316 0.608 NM_001004487
OR13J1
olfactory receptor, family 13, subfamily J, member 1
chr14_+_87560646 0.608 LOC283587
hypothetical protein LOC283587
chr7_-_18033970 0.607 NM_175886
PRPS1L1
phosphoribosyl pyrophosphate synthetase 1-like 1
chr1_-_166149867 0.601 NM_001167749
NM_018417
ADCY10

adenylate cyclase 10 (soluble)

chr19_+_15713200 0.599 NM_013938
OR10H3
olfactory receptor, family 10, subfamily H, member 3
chr10_-_98311813 0.597 TM9SF3
transmembrane 9 superfamily member 3
chr2_+_114390975 0.596 ACTR3
ARP3 actin-related protein 3 homolog (yeast)
chr1_+_119712918 0.594 NM_001005783
NM_016527
HAO2

hydroxyacid oxidase 2 (long chain)

chr15_-_73818013 0.594


chr6_+_55300225 0.593 NM_207410
GFRAL
GDNF family receptor alpha like
chr14_+_73073570 0.593 NM_001037161
ACOT1
acyl-CoA thioesterase 1
chr6_+_31661934 0.589 NM_205838
NM_205839
LST1

leukocyte specific transcript 1

chr6_-_133120587 0.589 NM_004665
VNN2
vanin 2
chr1_+_182287388 0.586 NM_001127394
NM_052965
TSEN15

tRNA splicing endonuclease 15 homolog (S. cerevisiae)

chr7_+_123083096 0.585 NM_207163
LMOD2
leiomodin 2 (cardiac)
chr1_+_35507145 0.584 NM_005095
ZMYM4
zinc finger, MYM-type 4
chr12_+_47009029 0.583 NM_181788
H1FNT
H1 histone family, member N, testis-specific
chr12_-_112058403 0.582 NM_001193520
NM_004658
RASAL1

RAS protein activator like 1 (GAP1 like)

chr9_+_132990760 0.581 NM_005085
NUP214
nucleoporin 214kDa
chr4_-_184480572 0.576 NM_001185149
CLDN24
claudin 24
chr20_-_16501911 0.574 NM_024704
KIF16B
kinesin family member 16B
chr12_-_25597444 0.571 NM_152590
NM_001145728
NM_001145729
IFLTD1


intermediate filament tail domain containing 1


chr4_+_186587537 0.571 NM_001114357
C4orf47
chromosome 4 open reading frame 47
chr3_+_123526700 0.569 NM_005213
CSTA
cystatin A (stefin A)
chr3_-_69254226 0.567 NM_198271
LMOD3
leiomodin 3 (fetal)
chr15_+_38296920 0.565 NM_001128628
NM_001128629
PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

chr12_-_11066436 0.560 NM_176888
TAS2R19
taste receptor, type 2, member 19
chrX_+_110252960 0.559 NM_001128168
NM_001128172
NM_001128173
PAK3


p21 protein (Cdc42/Rac)-activated kinase 3


chr5_+_132460779 0.558 HSPA4
heat shock 70kDa protein 4
chr1_-_100003936 0.554 NM_001013660
FRRS1
ferric-chelate reductase 1
chr6_-_133008834 0.551 NM_138327
TAAR1
trace amine associated receptor 1
chr12_-_10953427 0.549 NM_023920
TAS2R13
taste receptor, type 2, member 13
chr7_+_37746520 0.544 NM_181791
GPR141
G protein-coupled receptor 141
chr11_-_59707074 0.543 NM_022349
NM_152851
NM_152852
MS4A6A


membrane-spanning 4-domains, subfamily A, member 6A


chr6_-_24597717 0.542 NM_177483
NM_001503
GPLD1

glycosylphosphatidylinositol specific phospholipase D1

chr4_+_76700281 0.542 NM_178497
C4orf26
chromosome 4 open reading frame 26
chr18_+_606671 0.541 NM_199167
CLUL1
clusterin-like 1 (retinal)
chr5_-_156705250 0.532 NM_001001343
FNDC9
fibronectin type III domain containing 9
chr12_+_49922592 0.530 DAZAP2
DAZ associated protein 2
chr7_+_55947824 0.527 NM_182633
ZNF713
zinc finger protein 713
chr1_-_74971679 0.525 NM_001130042
NM_001130043
NM_001134759
NM_001889
CRYZ



crystallin, zeta (quinone reductase)



chr3_-_158700036 0.525 NM_024621
VEPH1
ventricular zone expressed PH domain homolog 1 (zebrafish)
chr2_-_111152075 0.524 NM_004336
BUB1
budding uninhibited by benzimidazoles 1 homolog (yeast)
chr1_+_169549996 0.523 NM_002022
FMO4
flavin containing monooxygenase 4
chr10_-_14412813 0.522 NM_018027
FRMD4A
FERM domain containing 4A
chr7_-_76667045 0.521 NM_006682
FGL2
fibrinogen-like 2
chr1_-_148854503 0.518


chr2_+_113591940 0.516 NM_000577
NM_173841
NM_173843
IL1RN


interleukin 1 receptor antagonist


chr6_+_47732181 0.510 NM_153839
GPR111
G protein-coupled receptor 111
chr2_-_219404755 0.509 NM_017431
PRKAG3
protein kinase, AMP-activated, gamma 3 non-catalytic subunit
chr13_+_42034871 0.508 NM_033012
TNFSF11
tumor necrosis factor (ligand) superfamily, member 11
chr19_-_56018815 0.507 NM_002257
KLK1
kallikrein 1
chr11_-_5835507 0.507 NM_001005168
OR52E8
olfactory receptor, family 52, subfamily E, member 8
chr9_+_129509088 0.506 NM_001012502
C9orf117
chromosome 9 open reading frame 117
chr9_-_4142182 0.505 NM_152629
GLIS3
GLIS family zinc finger 3
chr20_-_7869068 0.503 NM_017545
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr21_+_39745649 0.503 NM_007341
SH3BGR
SH3 domain binding glutamic acid-rich protein
chr6_-_112001590 0.502 NM_001164282
TRAF3IP2
TRAF3 interacting protein 2
chr6_+_55147029 0.501 NM_001526
HCRTR2
hypocretin (orexin) receptor 2
chr1_+_200775864 0.499 NM_001197131
PPP1R12B
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr2_+_201806410 0.497 NM_001080124
NM_001228
NM_033355
NM_033358
CASP8



caspase 8, apoptosis-related cysteine peptidase



chr1_+_246682699 0.496 NM_001004136
OR2T2
olfactory receptor, family 2, subfamily T, member 2
chr1_+_61319976 0.492 NM_001145512
NFIA
nuclear factor I/A
chr20_+_42417752 0.486 NM_001030003
NM_001030004
NM_175914
HNF4A


hepatocyte nuclear factor 4, alpha


chr21_-_30791298 0.484 NM_181610
KRTAP19-4
keratin associated protein 19-4
chr11_+_45899747 0.483 NM_152312
GYLTL1B
glycosyltransferase-like 1B
chr10_+_74540215 0.483 NM_015901
NUDT13
nudix (nucleoside diphosphate linked moiety X)-type motif 13
chr17_+_36599664 0.482 NM_001190460
KRTAP9-1
keratin associated protein 9-1
chr2_-_217248967 0.482 IGFBP5
insulin-like growth factor binding protein 5
chr9_-_103237851 0.479 NM_000035
ALDOB
aldolase B, fructose-bisphosphate
chr6_-_32892705 0.477 NM_002120
HLA-DOB
major histocompatibility complex, class II, DO beta
chr18_-_42810446 0.475 NM_145653
TCEB3C
transcription elongation factor B polypeptide 3C (elongin A3)
chr7_-_107930170 0.474 PNPLA8
patatin-like phospholipase domain containing 8
chr10_+_126620681 0.474 NM_017580
ZRANB1
zinc finger, RAN-binding domain containing 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.98 5.04e-12 GO:0007600 sensory perception
2.21 1.46e-09 GO:0007606 sensory perception of chemical stimulus
2.22 1.92e-08 GO:0007608 sensory perception of smell
1.52 2.41e-07 GO:0003008 system process
1.59 3.33e-07 GO:0050877 neurological system process

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.27 3.11e-09 GO:0004984 olfactory receptor activity
1.67 5.57e-06 GO:0004930 G-protein coupled receptor activity
1.46 2.29e-04 GO:0004888 transmembrane receptor activity
1.36 1.40e-03 GO:0004872 receptor activity
1.29 1.50e-02 GO:0004871 signal transducer activity
1.29 1.50e-02 GO:0060089 molecular transducer activity