Motif ID: CTCF.p2

Z-value: 9.123


Transcription factors associated with CTCF.p2:

Gene SymbolEntrez IDGene Name
CTCF 10664 CCCTC-binding factor (zinc finger protein)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CTCFchr16_+_661538100.845.3e-05Click!


Activity profile for motif CTCF.p2.

activity profile for motif CTCF.p2


Sorted Z-values histogram for motif CTCF.p2

Sorted Z-values for motif CTCF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CTCF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_-_2330712 16.459 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr16_-_2330738 15.750 NM_001089
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr16_-_2330594 14.862 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr4_-_41579325 12.542


chr9_-_93751900 11.700 NM_004560
ROR2
receptor tyrosine kinase-like orphan receptor 2
chr7_+_99919485 11.121 NM_173564
C7orf51
chromosome 7 open reading frame 51
chr11_+_46325457 10.565 NM_003646
DGKZ
diacylglycerol kinase, zeta
chr15_+_43510054 10.499 NM_032413
NM_197955
C15orf48

chromosome 15 open reading frame 48

chr13_-_51922731 10.215 NM_016075
VPS36
vacuolar protein sorting 36 homolog (S. cerevisiae)
chr22_-_20637188 10.032 PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr22_-_20637212 9.988 NM_014634
PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr11_-_63292688 9.593 NM_001144936
C11orf95
chromosome 11 open reading frame 95
chr11_-_130291584 9.521 NM_014758
SNX19
sorting nexin 19
chr1_-_95472096 9.517


chr11_-_130291527 9.406 SNX19
sorting nexin 19
chr1_+_95472298 9.385 NM_001128142
NM_015485
RWDD3

RWD domain containing 3

chr17_-_3696204 9.383 NM_001114118
NM_018553
C17orf85

chromosome 17 open reading frame 85

chr12_+_47494882 9.226 CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr16_+_69950116 9.169 NM_001740
NM_007088
CALB2

calbindin 2

chr22_+_23149855 9.141 ADORA2A
adenosine A2a receptor
chr16_+_69950138 9.048 CALB2
calbindin 2
chr3_-_198241079 9.042 NM_033316
NM_005929
MFI2

antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5

chr4_+_55907138 8.950 NM_024592
SRD5A3
steroid 5 alpha-reductase 3
chr16_-_11798507 8.916 ZC3H7A
zinc finger CCCH-type containing 7A
chr4_+_55907213 8.762 SRD5A3
steroid 5 alpha-reductase 3
chr3_+_142433361 8.398 NM_001037172
NM_152282
ACPL2

acid phosphatase-like 2

chr13_-_100039008 8.384 NM_001195087
A2LD1
AIG2-like domain 1
chr4_+_110574274 8.382 SEC24B
SEC24 family, member B (S. cerevisiae)
chr9_+_137733851 8.330 NM_020822
KCNT1
potassium channel, subfamily T, member 1
chr3_-_185218311 8.276 NM_001023587
NM_005688
ABCC5

ATP-binding cassette, sub-family C (CFTR/MRP), member 5

chr8_+_143805595 8.258 NM_016647
C8orf55
chromosome 8 open reading frame 55
chr5_-_118352122 8.253 NM_173666
DTWD2
DTW domain containing 2
chr7_+_72720093 8.216 NM_001077621
VPS37D
vacuolar protein sorting 37 homolog D (S. cerevisiae)
chr6_+_3794620 8.134 NM_012135
FAM50B
family with sequence similarity 50, member B
chr3_-_198240969 8.106 MFI2
antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
chr10_+_116571485 8.079 NM_001135051
NM_020940
FAM160B1

family with sequence similarity 160, member B1

chr4_+_110574376 8.071 NM_001042734
NM_006323
SEC24B

SEC24 family, member B (S. cerevisiae)

chr14_-_74148422 8.051 NM_000428
LTBP2
latent transforming growth factor beta binding protein 2
chr13_+_30672122 7.997 B3GALTL
beta 1,3-galactosyltransferase-like
chr1_+_36121400 7.921 EIF2C1
eukaryotic translation initiation factor 2C, 1
chr2_-_20714303 7.904 NM_022460
HS1BP3
HCLS1 binding protein 3
chr4_-_110574363 7.829 1/2-SBSRNA4
lncRNA_BC009800
chr11_-_118716244 7.822 MFRP
membrane frizzled-related protein
chr13_+_32058537 7.758 NM_015032
PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr22_+_18085891 7.741 SEPT5
septin 5
chr13_+_32058610 7.710 PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr5_-_136862786 7.702 NM_004598
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr19_-_52426055 7.688 NM_014417
BBC3
BCL2 binding component 3
chr17_+_17525497 7.607 NM_030665
RAI1
retinoic acid induced 1
chr8_-_145521108 7.590 DGAT1
diacylglycerol O-acyltransferase 1
chr1_-_224662396 7.527 PARP1
poly (ADP-ribose) polymerase 1
chr1_+_36121382 7.512 NM_012199
EIF2C1
eukaryotic translation initiation factor 2C, 1
chr7_-_5535432 7.492 ACTB
actin, beta
chr11_+_915874 7.475 AP2A2
adaptor-related protein complex 2, alpha 2 subunit
chr16_-_3049336 7.405


chr8_-_145521297 7.397 DGAT1
diacylglycerol O-acyltransferase 1
chr22_+_18085990 7.385 SEPT5-GP1BB
SEPT5
SEPT5-GP1BB read-through transcript
septin 5
chr11_+_915899 7.379 AP2A2
adaptor-related protein complex 2, alpha 2 subunit
chr1_+_36121403 7.336 EIF2C1
eukaryotic translation initiation factor 2C, 1
chr8_-_145521324 7.283 DGAT1
diacylglycerol O-acyltransferase 1
chr3_+_198214173 7.274 LOC100507057
MFI2
hypothetical LOC100507057
antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
chr2_-_232103352 7.271 NM_006056
NMUR1
neuromedin U receptor 1
chr11_+_915795 7.252 NM_012305
AP2A2
adaptor-related protein complex 2, alpha 2 subunit
chr1_-_224662413 7.235 PARP1
poly (ADP-ribose) polymerase 1
chr7_+_156435163 7.204 NM_138400
NOM1
nucleolar protein with MIF4G domain 1
chr1_-_224662307 7.204 PARP1
poly (ADP-ribose) polymerase 1
chr3_+_50272648 7.198


chr9_+_130005487 7.086 DNM1
dynamin 1
chr1_-_224662368 7.084 PARP1
poly (ADP-ribose) polymerase 1
chr11_-_116608020 7.071 NM_004716
PCSK7
proprotein convertase subtilisin/kexin type 7
chr8_-_145521344 7.059 NM_012079
DGAT1
diacylglycerol O-acyltransferase 1
chr7_+_75669130 7.052 NM_001110199
SRRM3
serine/arginine repetitive matrix 3
chr7_+_72720256 7.001 VPS37D
vacuolar protein sorting 37 homolog D (S. cerevisiae)
chr9_+_130005489 6.997 DNM1
dynamin 1
chr16_+_170334 6.994 NM_005331
HBQ1
hemoglobin, theta 1
chr9_+_115957537 6.990 COL27A1
collagen, type XXVII, alpha 1
chr13_+_32058630 6.980 PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr11_-_116607968 6.971 PCSK7
proprotein convertase subtilisin/kexin type 7
chr17_+_72376022 6.947 NM_144677
MGAT5B
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
chr7_-_5535726 6.932 ACTB
actin, beta
chr1_-_224662419 6.897 NM_001618
PARP1
poly (ADP-ribose) polymerase 1
chr21_-_37284351 6.891 NM_000411
HLCS
holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
chr22_-_21231421 6.844 NM_206955
NM_206956
NM_006115
NM_206953
NM_206954
PRAME




preferentially expressed antigen in melanoma




chr13_+_30672087 6.831 NM_194318
B3GALTL
beta 1,3-galactosyltransferase-like
chr7_+_148475373 6.771 NM_170686
ZNF398
zinc finger protein 398
chr13_+_32058651 6.694 PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr6_+_155096241 6.648 SCAF8
SR-related CTD-associated factor 8
chr12_+_50104859 6.637 NM_001039960
NM_004858
SLC4A8

solute carrier family 4, sodium bicarbonate cotransporter, member 8

chr5_-_179568730 6.625 NM_175062
RASGEF1C
RasGEF domain family, member 1C
chr8_+_145568526 6.612 NM_174922
ADCK5
aarF domain containing kinase 5
chr9_+_130005429 6.505 NM_001005336
NM_004408
DNM1

dynamin 1

chr17_+_17525571 6.449


chr3_-_188339882 6.437 NM_052969
RPL39L
ribosomal protein L39-like
chr4_+_110574420 6.419 SEC24B
SEC24 family, member B (S. cerevisiae)
chr1_-_224662156 6.410 PARP1
poly (ADP-ribose) polymerase 1
chr11_-_64267037 6.398 RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr11_+_62136788 6.380 NM_000327
ROM1
retinal outer segment membrane protein 1
chr17_+_60563963 6.375 RGS9
regulator of G-protein signaling 9
chr10_+_6284845 6.362 NM_004566
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr1_-_94147616 6.339 GCLM
glutamate-cysteine ligase, modifier subunit
chr8_+_21980315 6.309 EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr17_+_71097147 6.290 MYO15B
myosin XVB pseudogene
chr9_-_138742420 6.285 SNORA43
SNHG7
small nucleolar RNA, H/ACA box 43
small nucleolar RNA host gene 7 (non-protein coding)
chr2_-_132275703 6.125 NM_214461
C2orf27B
chromosome 2 open reading frame 27B
chr2_+_27163114 6.118 NM_000221
NM_006488
KHK

ketohexokinase (fructokinase)

chr17_+_60563917 6.117 NM_001081955
NM_001165933
NM_003835
RGS9


regulator of G-protein signaling 9


chr7_-_99517128 6.094 NM_017715
NM_032924
ZNF3

zinc finger protein 3

chr3_+_37468542 6.092 NM_002207
ITGA9
integrin, alpha 9
chrX_+_48907183 6.072 NM_001099680
MAGIX
MAGI family member, X-linked
chr2_+_186311599 6.021 NM_173651
FSIP2
fibrous sheath interacting protein 2
chr11_-_64247230 5.987 NM_015080
NM_138732
NRXN2

neurexin 2

chr22_-_49311439 5.897 NM_001169110
SCO2
SCO cytochrome oxidase deficient homolog 2 (yeast)
chr5_+_159558625 5.860 NM_001040442
FABP6
fatty acid binding protein 6, ileal
chr12_+_50104936 5.851 SLC4A8
solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr7_+_6596183 5.842 NM_024067
C7orf26
chromosome 7 open reading frame 26
chr8_-_74821610 5.839 STAU2
LOC729696
staufen, RNA binding protein, homolog 2 (Drosophila)
hypothetical protein LOC729696
chr15_-_76890626 5.797 NM_014272
ADAMTS7
ADAM metallopeptidase with thrombospondin type 1 motif, 7
chr16_-_730889 5.788 NM_022493
NARFL
nuclear prelamin A recognition factor-like
chr10_-_92607397 5.785 HTR7
5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)
chr15_+_72861470 5.776 NM_001127190
NM_004383
CSK

c-src tyrosine kinase

chr11_+_916021 5.747 AP2A2
adaptor-related protein complex 2, alpha 2 subunit
chr11_-_44928803 5.742 NM_001076787
NM_006034
TP53I11

tumor protein p53 inducible protein 11

chr9_-_139437534 5.695 NM_017820
EXD3
exonuclease 3'-5' domain containing 3
chr10_-_49534304 5.673 ARHGAP22
Rho GTPase activating protein 22
chr1_+_246167115 5.670 NM_175911
OR2L13
olfactory receptor, family 2, subfamily L, member 13
chr6_+_155096203 5.670 NM_014892
SCAF8
SR-related CTD-associated factor 8
chr17_-_18469569 5.662 CCDC144B
coiled-coil domain containing 144B
chr19_-_43439011 5.661 NM_033256
PPP1R14A
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr2_-_218865451 5.653 NM_022152
TMBIM1
transmembrane BAX inhibitor motif containing 1
chr9_+_128662756 5.636 NM_001099270
ZBTB34
zinc finger and BTB domain containing 34
chr10_-_76665691 5.612 NM_144589
COMTD1
catechol-O-methyltransferase domain containing 1
chr9_+_130222943 5.604 CERCAM
cerebral endothelial cell adhesion molecule
chr9_+_138680064 5.602 EGFL7
EGF-like-domain, multiple 7
chr19_+_38485583 5.533 LOC80054
hypothetical LOC80054
chr15_-_62125562 5.499 NM_014326
DAPK2
death-associated protein kinase 2
chr11_+_111666133 5.496


chr19_-_38485269 5.482 NM_004364
CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr17_+_1905104 5.466 NM_006497
HIC1
hypermethylated in cancer 1
chr11_+_61204392 5.456 NM_006133
DAGLA
diacylglycerol lipase, alpha
chr17_-_23244499 5.409 NM_001076680
C17orf108
chromosome 17 open reading frame 108
chr19_-_38485281 5.393 CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr1_-_37752925 5.387 NM_022756
MEAF6
MYST/Esa1-associated factor 6
chr11_+_116608447 5.379 NM_207343
NM_001077239
RNF214

ring finger protein 214

chr9_-_139437471 5.377 EXD3
exonuclease 3'-5' domain containing 3
chr12_+_103133631 5.341 NM_001093771
TXNRD1
thioredoxin reductase 1
chr5_-_70621688 5.324 SMA4
glucuronidase, beta pseudogene
chr10_+_102749222 5.312 LZTS2
leucine zipper, putative tumor suppressor 2
chr1_-_94147574 5.305 NM_002061
GCLM
glutamate-cysteine ligase, modifier subunit
chr10_-_90332927 5.278 NM_001031709
NM_018363
RNLS

renalase, FAD-dependent amine oxidase

chr17_-_30470745 5.229 RAD51L3
RAD51-like 3 (S. cerevisiae)
chr17_-_30470976 5.180 NM_001142571
NM_002878
NM_133629
RAD51L3


RAD51-like 3 (S. cerevisiae)


chr1_-_94147537 5.131 GCLM
glutamate-cysteine ligase, modifier subunit
chr3_-_49732062 5.067 NM_198722
AMIGO3
adhesion molecule with Ig-like domain 3
chr8_+_145568555 5.033 ADCK5
aarF domain containing kinase 5
chr10_-_103593529 5.023 NM_014591
NM_173191
NM_173192
NM_173193
NM_173195
NM_173197
KCNIP2





Kv channel interacting protein 2





chr19_-_11425568 5.014 ELAVL3
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)
chr9_-_139437404 4.965 EXD3
exonuclease 3'-5' domain containing 3
chr7_-_134506070 4.953 NM_024033
C7orf49
chromosome 7 open reading frame 49
chrX_+_151860870 4.951 NM_001178115
ZNF185
zinc finger protein 185 (LIM domain)
chr1_+_228844811 4.949 NM_001145036
NM_007357
COG2

component of oligomeric golgi complex 2

chr17_-_77588844 4.949 NM_001195218
NM_016286
DCXR

dicarbonyl/L-xylulose reductase

chr22_-_49311722 4.941 NM_001169109
SCO2
SCO cytochrome oxidase deficient homolog 2 (yeast)
chr4_-_141568210 4.937 NM_001130675
NM_004362
CLGN

calmegin

chr9_-_133605037 4.929 RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr11_+_124539768 4.928 NM_022062
PKNOX2
PBX/knotted 1 homeobox 2
chr8_-_145881968 4.927 ARHGAP39
Rho GTPase activating protein 39
chr19_+_43585644 4.892 FAM98C
family with sequence similarity 98, member C
chr11_+_9736408 4.877 LOC283104
hypothetical LOC283104
chr20_+_3749164 4.865 NM_018347
C20orf29
chromosome 20 open reading frame 29
chr14_-_92651896 4.864 NM_001142593
NM_001142594
NM_014216
ITPK1


inositol 1,3,4-triphosphate 5/6 kinase


chr6_+_155096494 4.820 SCAF8
SR-related CTD-associated factor 8
chr11_-_788196 4.819 NM_001191061
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr15_+_72861767 4.799 CSK
c-src tyrosine kinase
chr11_-_64268126 4.796 NM_001098671
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr1_+_221966849 4.786 CAPN2
calpain 2, (m/II) large subunit
chr17_-_71412737 4.771 NM_032478
MRPL38
mitochondrial ribosomal protein L38
chr17_-_39796649 4.755 NM_198475
FAM171A2
family with sequence similarity 171, member A2
chr3_+_49183983 4.753 NM_173546
KLHDC8B
kelch domain containing 8B
chrX_+_119268713 4.751


chr1_-_6684465 4.737 DNAJC11
DnaJ (Hsp40) homolog, subfamily C, member 11
chr1_-_145110346 4.731 PRKAB2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr19_+_10843369 4.723 CARM1
coactivator-associated arginine methyltransferase 1
chr16_+_1696162 4.697 NM_001040439
NM_015133
MAPK8IP3

mitogen-activated protein kinase 8 interacting protein 3

chr1_+_228844834 4.696 COG2
component of oligomeric golgi complex 2
chr1_+_191357843 4.671 CDC73
cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr19_-_43438818 4.653 PPP1R14A
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr15_-_36644122 4.634 NM_001128602
NM_005739
RASGRP1

RAS guanyl releasing protein 1 (calcium and DAG-regulated)

chr19_+_12810258 4.633 NM_014975
MAST1
microtubule associated serine/threonine kinase 1
chr16_-_69271428 4.628 MTSS1L
metastasis suppressor 1-like
chr1_+_191357819 4.617 CDC73
cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr7_+_148590152 4.605 NM_001195220
ZNF783
zinc finger family member 783
chr17_+_19853200 4.589 SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr9_-_138378061 4.566 NM_001080849
DNLZ
DNL-type zinc finger
chr5_+_175807978 4.560 FAF2
Fas associated factor family member 2
chr6_+_138767151 4.556 HEBP2
heme binding protein 2
chr19_-_38485161 4.548


chr7_+_98314020 4.524 NM_003496
TRRAP
transformation/transcription domain-associated protein
chr5_+_175807986 4.499 FAF2
Fas associated factor family member 2
chr9_-_100598315 4.487 NM_173551
ANKS6
ankyrin repeat and sterile alpha motif domain containing 6
chr8_-_74821636 4.486 NM_001164380
NM_001164381
NM_001164382
NM_001164383
NM_001164385
NM_014393
STAU2





staufen, RNA binding protein, homolog 2 (Drosophila)






Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.35 2.55e-02 GO:0016043 cellular component organization
1.41 3.36e-02 GO:0071842 cellular component organization at cellular level

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.53 3.38e-04 GO:0005829 cytosol
1.19 4.27e-04 GO:0005737 cytoplasm
1.13 4.69e-04 GO:0005622 intracellular
1.13 1.46e-03 GO:0044424 intracellular part
1.21 1.52e-02 GO:0044444 cytoplasmic part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.22 3.65e-04 GO:0005515 protein binding
2.11 7.11e-04 GO:0008092 cytoskeletal protein binding