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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: E2F1..5.p2

Z-value: 1.452

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr3_-_124650081	1.650	NM_183357	ADCY5	adenylate cyclase 5
chr13_-_25523164	1.539	NM_001007538	SHISA2	shisa homolog 2 (Xenopus laevis)
chr7_-_106088565	1.386	NM_175884	FLJ36031	hypothetical protein FLJ36031
chr10_-_25281510	1.289	NM_020200	PRTFDC1	phosphoribosyl transferase domain containing 1
chr14_+_85069217	1.193
chr1_-_226712140	1.121	NM_033445	HIST3H2A	histone cluster 3, H2a
chr3_-_140148671	1.090	NM_023067	FOXL2	forkhead box L2
chr1_+_226712430	1.076	NM_175055	HIST3H2BB	histone cluster 3, H2bb
chr4_-_170915602	1.019	NM_017867	C4orf27	chromosome 4 open reading frame 27
chr12_-_75983329	0.973	NM_203394	E2F7	E2F transcription factor 7
chr2_-_136350472	0.966	NM_005915	MCM6	minichromosome maintenance complex component 6
chr5_-_177950161	0.940	NM_173465	COL23A1	collagen, type XXIII, alpha 1
chr11_-_63195371	0.900		ATL3	atlastin GTPase 3
chr8_-_24869945	0.876	NM_006158	NEFL	neurofilament, light polypeptide
chr3_+_140148765	0.832	NM_001040061	C3orf72	chromosome 3 open reading frame 72
chr11_+_64785888	0.806	NM_002689	POLA2	polymerase (DNA directed), alpha 2 (70kD subunit)
chr19_-_60587414	0.785	NM_001190764	LOC388564	hypothetical protein LOC388564
chr2_-_136350404	0.779		MCM6	minichromosome maintenance complex component 6
chr7_+_98084531	0.774	NM_002523	NPTX2	neuronal pentraxin II
chr17_+_40089270	0.774	NM_001145080	C17orf104	chromosome 17 open reading frame 104
chr5_-_74098641	0.751	NM_032380 NM_170681 NM_170691	GFM2	G elongation factor, mitochondrial 2
chr15_-_68971665	0.748	NM_020147	THAP10	THAP domain containing 10
chr7_-_526005	0.727	NM_002607 NM_033023	PDGFA	platelet-derived growth factor alpha polypeptide
chr2_-_31215074	0.725	NM_024572	GALNT14	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr6_+_72949092	0.716		RIMS1	regulating synaptic membrane exocytosis 1
chr1_+_149309703	0.711	NM_144618	GABPB2	GA binding protein transcription factor, beta subunit 2
chr22_-_19685998	0.698		THAP7	THAP domain containing 7
chr4_+_134292630	0.683		PCDH10	protocadherin 10
chr4_+_39734902	0.681	NM_018177	N4BP2	NEDD4 binding protein 2
chrX_+_101792949	0.679	NM_001099410 NM_001099411 NM_014710 NM_001184727	GPRASP1	G protein-coupled receptor associated sorting protein 1
chr12_-_55013713	0.678	NM_001127460	PAN2	PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr5_+_126654354	0.673	NM_032446	MEGF10	multiple EGF-like-domains 10
chr19_+_4860447	0.670	NM_001048201	UHRF1	ubiquitin-like with PHD and ring finger domains 1
chr9_-_132803809	0.667		FIBCD1	fibrinogen C domain containing 1
chr15_+_68971835	0.657	NM_001199017 NM_017691 NM_001199018	LRRC49	leucine rich repeat containing 49
chr16_-_4263056	0.651		TFAP4	transcription factor AP-4 (activating enhancer binding protein 4)
chr12_-_55013987	0.645	NM_001166279 NM_014871	PAN2	PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chrX_-_131451675	0.633	NM_001170704	MBNL3	muscleblind-like 3 (Drosophila)
chr1_+_93317374	0.629	NM_001164391 NM_001164392 NM_001164393 NM_007358	MTF2	metal response element binding transcription factor 2
chr15_+_90198567	0.629		SLCO3A1	solute carrier organic anion transporter family, member 3A1
chr19_-_2187246	0.627	NM_018049	PLEKHJ1	pleckstrin homology domain containing, family J member 1
chr4_-_39655944	0.626	NM_001100399 NM_001100400	PDS5A	PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr3_+_16901455	0.615	NM_001144382	PLCL2	phospholipase C-like 2
chr22_+_40425448	0.602	NM_152513	MEI1	meiosis inhibitor 1
chr8_-_124477639	0.602		ATAD2	ATPase family, AAA domain containing 2
chr19_-_2187648	0.595		PLEKHJ1	pleckstrin homology domain containing, family J member 1
chr6_-_27208507	0.595	NM_021058	HIST1H2BJ	histone cluster 1, H2bj
chr7_+_88226617	0.575	NM_181646	ZNF804B	zinc finger protein 804B
chr2_+_27293737	0.560	NM_004341	CAD	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr7_-_44854222	0.560	NM_012412 NM_138635 NM_201436 NM_201516 NM_201517	H2AFV	H2A histone family, member V
chr9_-_25668230	0.558		TUSC1	tumor suppressor candidate 1
chr11_+_12987455	0.557	NM_001080521	RASSF10	Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
chr8_+_128817494	0.554	NM_002467	MYC	v-myc myelocytomatosis viral oncogene homolog (avian)
chr9_-_132804057	0.554	NM_032843	FIBCD1	fibrinogen C domain containing 1
chr13_+_102047286	0.553	NM_003291	TPP2	tripeptidyl peptidase II
chr5_-_146869613	0.553		DPYSL3	dihydropyrimidinase-like 3
chr2_+_27293846	0.552		CAD	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr1_-_148050534	0.552	NM_001024599 NM_001161334	HIST2H2BF	histone cluster 2, H2bf
chr3_-_53055078	0.552	NM_001005158 NM_016329	SFMBT1	Scm-like with four mbt domains 1
chr8_+_99508425	0.543	NM_020697	KCNS2	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2
chr15_+_90198031	0.540		SLCO3A1	solute carrier organic anion transporter family, member 3A1
chr5_+_74098828	0.534	NM_014886	NSA2	NSA2 ribosome biogenesis homolog (S. cerevisiae)
chr1_-_29321599	0.533	NM_001171868	TMEM200B	transmembrane protein 200B
chr13_+_31787594	0.526	NM_000059	BRCA2	breast cancer 2, early onset
chr15_-_70863078	0.525		ADPGK	ADP-dependent glucokinase
chr13_-_109236897	0.524	NM_003749	IRS2	insulin receptor substrate 2
chr2_-_31214788	0.523		GALNT14	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr5_-_146869811	0.523	NM_001197294	DPYSL3	dihydropyrimidinase-like 3
chrX_+_104953215	0.516		NRK	Nik related kinase
chr22_+_34126104	0.512	NM_006739	MCM5	minichromosome maintenance complex component 5
chr11_-_63195624	0.511	NM_015459	ATL3	atlastin GTPase 3
chr8_-_124477846	0.510		ATAD2	ATPase family, AAA domain containing 2
chr15_+_78775008	0.509		FAM108C1	family with sequence similarity 108, member C1
chr1_+_13782838	0.509	NM_006474 NM_198389	PDPN	podoplanin
chr15_+_45263517	0.509	NM_001198999	SEMA6D	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chrX_+_104953187	0.504	NM_198465	NRK	Nik related kinase
chr11_-_14869761	0.502		CYP2R1	cytochrome P450, family 2, subfamily R, polypeptide 1
chr19_+_2187815	0.497	NM_007165	SF3A2	splicing factor 3a, subunit 2, 66kDa
chr1_-_68470585	0.496	NM_001002292 NM_001193334 NM_024911	WLS	wntless homolog (Drosophila)
chr6_+_27208763	0.494	NM_021064	HIST1H2AG	histone cluster 1, H2ag
chr9_+_115678365	0.487	NM_133374	ZNF618	zinc finger protein 618
chrX_-_135677022	0.483		ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr4_-_78959532	0.479	NM_144571	CNOT6L	CCR4-NOT transcription complex, subunit 6-like
chr16_+_2959467	0.478		PAQR4	progestin and adipoQ receptor family member IV
chr22_+_34126154	0.477		MCM5	minichromosome maintenance complex component 5
chr10_+_96295511	0.476	NM_018063	HELLS	helicase, lymphoid-specific
chr7_-_73306629	0.474		RFC2	replication factor C (activator 1) 2, 40kDa
chr3_+_144321286	0.469	NM_004267	CHST2	carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
chr9_-_132804243	0.465	NM_001145106	FIBCD1	fibrinogen C domain containing 1
chr12_-_47396724	0.463	NM_001240	CCNT1	cyclin T1
chr1_-_47552238	0.462	NM_001048166 NM_003035	STIL	SCL/TAL1 interrupting locus
chr7_-_73306668	0.462	NM_002914 NM_181471	RFC2	replication factor C (activator 1) 2, 40kDa
chr4_+_106287391	0.462	NM_001127208 NM_017628	TET2	tet oncogene family member 2
chr15_+_30694982	0.460	NM_014783 NM_199357	ARHGAP11A	Rho GTPase activating protein 11A
chr15_-_70863110	0.458		ADPGK	ADP-dependent glucokinase
chr6_-_144370947	0.456		PLAGL1	pleiomorphic adenoma gene-like 1
chr7_-_44854145	0.456		H2AFV	H2A histone family, member V
chr4_-_164473107	0.456	NM_000909	NPY1R	neuropeptide Y receptor Y1
chr7_-_44854183	0.456		H2AFV	H2A histone family, member V
chr15_+_62539831	0.452		ZNF609	zinc finger protein 609
chr7_-_44854092	0.450		H2AFV	H2A histone family, member V
chr7_+_128861471	0.450	NM_001134336 NM_020704	FAM40B	family with sequence similarity 40, member B
chr7_-_44854188	0.440		H2AFV	H2A histone family, member V
chr9_+_17124974	0.438	NM_001114395 NM_017738	CNTLN	centlein, centrosomal protein
chr15_+_90197884	0.437	NM_001145044 NM_013272	SLCO3A1	solute carrier organic anion transporter family, member 3A1
chr5_-_39110251	0.436	NM_152756	RICTOR	RPTOR independent companion of MTOR, complex 2
chr15_-_70863124	0.435		ADPGK	ADP-dependent glucokinase
chr14_-_80757327	0.435	NM_201595	GTF2A1	general transcription factor IIA, 1, 19/37kDa
chr5_-_140978664	0.435		DIAPH1	diaphanous homolog 1 (Drosophila)
chr7_-_77163475	0.433
chr4_+_154485224	0.429	NM_032117	MND1	meiotic nuclear divisions 1 homolog (S. cerevisiae)
chr1_-_147665783	0.426		HIST2H2BF	histone cluster 2, H2bf
chr16_+_28798735	0.425		ATP2A1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr4_+_30330963	0.425	NM_001173523 NM_002589 NM_032456 NM_032457	PCDH7	protocadherin 7
chr15_-_70863115	0.422		ADPGK	ADP-dependent glucokinase
chr5_-_140978751	0.421	NM_001079812 NM_005219	DIAPH1	diaphanous homolog 1 (Drosophila)
chr8_-_124477869	0.420	NM_014109	ATAD2	ATPase family, AAA domain containing 2
chr8_+_128817658	0.417		MYC	v-myc myelocytomatosis viral oncogene homolog (avian)
chr4_+_55218663	0.417	NM_000222 NM_001093772	KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
chr3_-_150286812	0.410	NM_003071 NM_139048	HLTF	helicase-like transcription factor
chr3_+_64645819	0.408		LOC100507098	hypothetical LOC100507098
chr1_+_115198977	0.407	NM_003176	SYCP1	synaptonemal complex protein 1
chr2_-_31214868	0.406
chr8_-_124477850	0.400		ATAD2	ATPase family, AAA domain containing 2
chr4_+_30331543	0.397		PCDH7	protocadherin 7
chr4_-_115120251	0.393	NM_024590	ARSJ	arylsulfatase family, member J
chr1_-_227761038	0.391	NM_012089	ABCB10	ATP-binding cassette, sub-family B (MDR/TAP), member 10
chr1_-_36008009	0.391	NM_001190481 NM_022111	CLSPN	claspin
chr11_+_63498590	0.389	NM_004074	COX8A	cytochrome c oxidase subunit VIIIA (ubiquitous)
chr3_+_38363299	0.388		XYLB	xylulokinase homolog (H. influenzae)
chr19_-_54520246	0.388	NM_014037	SLC6A16	solute carrier family 6, member 16
chr5_+_175807992	0.388		FAF2	Fas associated factor family member 2
chr6_+_108988797	0.387		FOXO3	forkhead box O3
chr3_+_38363226	0.387	NM_005108	XYLB	xylulokinase homolog (H. influenzae)
chrX_-_152889815	0.387	NM_005334	HCFC1	host cell factor C1 (VP16-accessory protein)
chr3_+_5139032	0.386		ARL8B	ADP-ribosylation factor-like 8B
chr9_+_132558972	0.384	NM_014285	EXOSC2	exosome component 2
chrX_-_57953578	0.384	NM_007156	ZXDA	zinc finger, X-linked, duplicated A
chr7_+_90063543	0.384		CDK14	cyclin-dependent kinase 14
chr1_+_109838180	0.382	NM_001134402 NM_001134400 NM_001134403 NM_001134404 NM_182580	CYB561D1	cytochrome b-561 domain containing 1
chr10_-_53129315	0.381	NM_015235	CSTF2T	cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
chr4_-_39655554	0.381		PDS5A	PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr3_+_38363292	0.381		XYLB	xylulokinase homolog (H. influenzae)
chr5_-_39110235	0.379		RICTOR	RPTOR independent companion of MTOR, complex 2
chr7_+_120378052	0.378	NM_019071 NM_198267	ING3	inhibitor of growth family, member 3
chr5_-_54504590	0.376	NM_001145734 NM_001170402 NM_152623	CDC20B	cell division cycle 20 homolog B (S. cerevisiae)
chr5_+_175807986	0.372		FAF2	Fas associated factor family member 2
chr11_+_73981274	0.370	NM_006591	POLD3	polymerase (DNA-directed), delta 3, accessory subunit
chr10_+_99463446	0.367	NM_031484	MARVELD1	MARVEL domain containing 1
chr10_+_99463468	0.367		MARVELD1	MARVEL domain containing 1
chr5_-_140978747	0.367		DIAPH1	diaphanous homolog 1 (Drosophila)
chr6_+_26333361	0.366	NM_003532	HIST1H3E	histone cluster 1, H3e
chr11_-_77383307	0.366		INTS4	integrator complex subunit 4
chr9_-_97119677	0.364	NM_000136	FANCC	Fanconi anemia, complementation group C
chr5_+_175807961	0.363	NM_014613	FAF2	Fas associated factor family member 2
chr2_-_174538197	0.360		SP3	Sp3 transcription factor
chr5_-_140978744	0.358		DIAPH1	diaphanous homolog 1 (Drosophila)
chr6_+_84626083	0.356	NM_016230	CYB5R4	cytochrome b5 reductase 4
chr4_+_126457016	0.354	NM_024582	FAT4	FAT tumor suppressor homolog 4 (Drosophila)
chr16_-_46976649	0.354	NM_003031	SIAH1	seven in absentia homolog 1 (Drosophila)
chr11_-_77383359	0.353	NM_033547	INTS4	integrator complex subunit 4
chr9_-_103289154	0.352	NM_032342	C9orf125	chromosome 9 open reading frame 125
chr13_+_107668714	0.352	NM_032859	ABHD13	abhydrolase domain containing 13
chr5_+_175807978	0.351		FAF2	Fas associated factor family member 2
chr18_+_17446227	0.347	NM_006938	SNRPD1	small nuclear ribonucleoprotein D1 polypeptide 16kDa
chr22_+_34126294	0.344		MCM5	minichromosome maintenance complex component 5
chrX_-_99873152	0.343	NM_001174068 NM_080737	SYTL4	synaptotagmin-like 4
chr1_+_143920424	0.340	NM_203458	NOTCH2NL	notch 2 N-terminal like
chr2_+_71534260	0.339	NM_001130976 NM_001130977 NM_001130978 NM_001130979 NM_001130980 NM_001130981 NM_003494	DYSF	dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
chr3_+_5139009	0.336		ARL8B	ADP-ribosylation factor-like 8B
chr15_+_43510054	0.335	NM_032413 NM_197955	C15orf48	chromosome 15 open reading frame 48
chr3_+_5139028	0.334		ARL8B	ADP-ribosylation factor-like 8B
chr4_+_30331289	0.332		PCDH7	protocadherin 7
chrX_+_118592879	0.332		UBE2A	ubiquitin-conjugating enzyme E2A (RAD6 homolog)
chr15_-_70863166	0.331	NM_031284	ADPGK	ADP-dependent glucokinase
chr10_+_13243553	0.330	NM_018518 NM_182751	MCM10	minichromosome maintenance complex component 10
chr11_-_66482366	0.330	NM_000920 NM_001040716	PC	pyruvate carboxylase
chr5_+_176007095	0.329		TSPAN17	tetraspanin 17
chrX_-_131919896	0.329		HS6ST2	heparan sulfate 6-O-sulfotransferase 2
chr1_+_238321794	0.326	NM_020066	FMN2	formin 2
chr4_+_134293171	0.322		PCDH10	protocadherin 10
chr8_+_145662510	0.319	NM_145754	KIFC2	kinesin family member C2
chr6_-_27948065	0.319	NM_003533	HIST1H3I	histone cluster 1, H3i
chrX_+_106758395	0.318		PRPS1	phosphoribosyl pyrophosphate synthetase 1
chr3_+_145173585	0.316		C3orf58	chromosome 3 open reading frame 58
chr17_+_5126275	0.315	NM_001083585 NM_004703	RABEP1	rabaptin, RAB GTPase binding effector protein 1
chr10_-_73784661	0.310		DNAJB12	DnaJ (Hsp40) homolog, subfamily B, member 12
chr9_+_113327259	0.309	NM_001007169 NM_133464	ZNF483	zinc finger protein 483
chr15_-_73535176	0.307	NM_001145357	SIN3A	SIN3 homolog A, transcription regulator (yeast)
chrX_+_44617346	0.307	NM_021140	KDM6A	lysine (K)-specific demethylase 6A
chr14_+_64949447	0.307		FUT8	fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr16_+_88169612	0.306	NM_014427 NM_153636	CPNE7	copine VII
chr18_+_17446289	0.304		SNRPD1	small nuclear ribonucleoprotein D1 polypeptide 16kDa
chr6_+_108988761	0.303	NM_001455	FOXO3	forkhead box O3
chr1_+_100371293	0.302	NM_019083	CCDC76	coiled-coil domain containing 76
chr1_+_164063684	0.302		UCK2	uridine-cytidine kinase 2
chr1_-_100370994	0.300	NM_194292	SASS6	spindle assembly 6 homolog (C. elegans)
chr3_+_5138929	0.298	NM_018184	ARL8B	ADP-ribosylation factor-like 8B
chr5_+_68521123	0.298	NM_022909	CENPH	centromere protein H
chr5_+_75414994	0.297	NM_014979	SV2C	synaptic vesicle glycoprotein 2C

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.79	1.29e-21	GO:0090304	nucleic acid metabolic process
1.67	1.90e-20	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.45	4.78e-17	GO:0044260	cellular macromolecule metabolic process
2.08	3.74e-16	GO:0007049	cell cycle
1.53	3.67e-15	GO:0034641	cellular nitrogen compound metabolic process
1.50	2.87e-14	GO:0006807	nitrogen compound metabolic process
1.37	8.52e-14	GO:0043170	macromolecule metabolic process
1.68	1.04e-11	GO:0016070	RNA metabolic process
2.15	2.57e-11	GO:0022403	cell cycle phase
2.04	2.60e-11	GO:0022402	cell cycle process
2.21	4.07e-11	GO:0051276	chromosome organization
1.27	7.06e-11	GO:0044238	primary metabolic process
1.62	2.11e-10	GO:0010467	gene expression
2.25	6.05e-10	GO:0016071	mRNA metabolic process
1.26	1.22e-09	GO:0044237	cellular metabolic process
2.16	1.55e-09	GO:0006259	DNA metabolic process
1.14	2.82e-09	GO:0009987	cellular process
2.41	8.40e-09	GO:0006397	mRNA processing
1.45	9.98e-09	GO:0071841	cellular component organization or biogenesis at cellular level
1.38	3.62e-08	GO:0016043	cellular component organization
1.45	4.01e-08	GO:0071842	cellular component organization at cellular level
1.37	6.23e-08	GO:0071840	cellular component organization or biogenesis
2.01	7.25e-08	GO:0006396	RNA processing
3.68	1.09e-07	GO:0065004	protein-DNA complex assembly
3.60	1.10e-07	GO:0071824	protein-DNA complex subunit organization
2.12	1.47e-07	GO:0006974	response to DNA damage stimulus
3.77	2.31e-07	GO:0031497	chromatin assembly
1.41	5.96e-07	GO:0051171	regulation of nitrogen compound metabolic process
1.20	8.17e-07	GO:0008152	metabolic process
1.97	2.03e-06	GO:0000278	mitotic cell cycle
2.39	2.29e-06	GO:0008380	RNA splicing
2.29	3.21e-06	GO:0006281	DNA repair
3.47	4.28e-06	GO:0034728	nucleosome organization
2.12	4.29e-06	GO:0000279	M phase
3.10	4.39e-06	GO:0006310	DNA recombination
2.97	4.98e-06	GO:0071103	DNA conformation change
2.78	5.28e-06	GO:0006260	DNA replication
1.42	5.65e-06	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.32	7.25e-06	GO:0031323	regulation of cellular metabolic process
3.57	7.42e-06	GO:0006334	nucleosome assembly
2.05	8.69e-06	GO:0006325	chromatin organization
1.38	9.98e-06	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.38	9.98e-06	GO:0031326	regulation of cellular biosynthetic process
1.52	1.15e-05	GO:0006996	organelle organization
1.51	1.38e-05	GO:0034645	cellular macromolecule biosynthetic process
3.08	1.60e-05	GO:0006323	DNA packaging
1.39	1.73e-05	GO:0010556	regulation of macromolecule biosynthetic process
1.37	1.93e-05	GO:0009889	regulation of biosynthetic process
2.17	2.14e-05	GO:0034622	cellular macromolecular complex assembly
2.97	2.53e-05	GO:0006333	chromatin assembly or disassembly
1.74	2.62e-05	GO:0033554	cellular response to stress
2.27	3.34e-05	GO:0051325	interphase
1.49	3.41e-05	GO:0009059	macromolecule biosynthetic process
1.31	3.59e-05	GO:0080090	regulation of primary metabolic process
1.93	1.35e-04	GO:0034621	cellular macromolecular complex subunit organization
2.50	1.89e-04	GO:0000375	RNA splicing, via transesterification reactions
1.27	2.61e-04	GO:0019222	regulation of metabolic process
2.50	2.74e-04	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.50	2.74e-04	GO:0000398	nuclear mRNA splicing, via spliceosome
2.18	3.27e-04	GO:0051329	interphase of mitotic cell cycle
3.02	3.64e-04	GO:0051320	S phase
1.74	3.65e-04	GO:0065003	macromolecular complex assembly
1.35	3.90e-04	GO:0010468	regulation of gene expression
1.37	7.41e-04	GO:0051252	regulation of RNA metabolic process
1.17	8.25e-04	GO:0050794	regulation of cellular process
1.29	8.50e-04	GO:0060255	regulation of macromolecule metabolic process
2.96	9.33e-04	GO:0000084	S phase of mitotic cell cycle
3.52	1.11e-03	GO:0006261	DNA-dependent DNA replication
1.62	1.24e-03	GO:0006351	transcription, DNA-dependent
1.63	1.25e-03	GO:0043933	macromolecular complex subunit organization
1.52	1.43e-03	GO:0044085	cellular component biogenesis
2.66	1.55e-03	GO:0000082	G1/S transition of mitotic cell cycle
1.36	2.47e-03	GO:0006355	regulation of transcription, DNA-dependent
1.33	3.08e-03	GO:0044249	cellular biosynthetic process
1.64	4.49e-03	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.62	4.97e-03	GO:0051173	positive regulation of nitrogen compound metabolic process
1.52	5.50e-03	GO:0022607	cellular component assembly
1.94	8.22e-03	GO:0010564	regulation of cell cycle process
2.45	9.56e-03	GO:0000226	microtubule cytoskeleton organization
1.53	9.94e-03	GO:0032774	RNA biosynthetic process
1.14	1.23e-02	GO:0050789	regulation of biological process
1.30	1.29e-02	GO:0009058	biosynthetic process
1.67	1.35e-02	GO:0051726	regulation of cell cycle
1.64	1.71e-02	GO:0010628	positive regulation of gene expression
9.23	1.82e-02	GO:0007064	mitotic sister chromatid cohesion
2.72	2.03e-02	GO:0007059	chromosome segregation
1.59	2.04e-02	GO:0071844	cellular component assembly at cellular level
1.97	2.73e-02	GO:0000280	nuclear division
1.97	2.73e-02	GO:0007067	mitosis
6.16	3.48e-02	GO:0006297	nucleotide-excision repair, DNA gap filling
1.50	3.58e-02	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.85	3.60e-02	GO:0016568	chromatin modification
1.29	3.73e-02	GO:0048522	positive regulation of cellular process
2.09	4.59e-02	GO:0071156	regulation of cell cycle arrest
1.12	4.90e-02	GO:0065007	biological regulation
1.42	4.93e-02	GO:0009893	positive regulation of metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.51	3.68e-35	GO:0005634	nucleus
1.88	6.00e-28	GO:0044428	nuclear part
1.92	8.48e-25	GO:0031981	nuclear lumen
1.25	1.38e-24	GO:0043226	organelle
1.20	7.22e-24	GO:0044424	intracellular part
1.24	7.93e-24	GO:0043229	intracellular organelle
1.19	8.02e-24	GO:0005622	intracellular
1.27	2.86e-23	GO:0043227	membrane-bounded organelle
1.78	5.80e-23	GO:0070013	intracellular organelle lumen
1.27	6.19e-23	GO:0043231	intracellular membrane-bounded organelle
2.06	2.42e-22	GO:0005654	nucleoplasm
1.74	1.64e-21	GO:0043233	organelle lumen
1.72	1.14e-20	GO:0031974	membrane-enclosed lumen
1.33	1.24e-14	GO:0044446	intracellular organelle part
1.32	4.33e-14	GO:0044422	organelle part
2.33	2.38e-13	GO:0005694	chromosome
2.39	6.60e-12	GO:0044427	chromosomal part
2.00	3.11e-10	GO:0044451	nucleoplasm part
1.38	4.59e-10	GO:0032991	macromolecular complex
2.80	1.62e-09	GO:0000785	chromatin
1.41	3.01e-08	GO:0043228	non-membrane-bounded organelle
1.41	3.01e-08	GO:0043232	intracellular non-membrane-bounded organelle
2.97	6.65e-08	GO:0044454	nuclear chromosome part
2.70	1.64e-07	GO:0000228	nuclear chromosome
3.43	3.38e-06	GO:0032993	protein-DNA complex
1.05	4.12e-05	GO:0044464	cell part
1.05	4.26e-05	GO:0005623	cell
1.86	5.47e-05	GO:0030529	ribonucleoprotein complex
3.30	1.65e-04	GO:0000790	nuclear chromatin
2.29	1.71e-04	GO:0016604	nuclear body
4.66	2.26e-04	GO:0005657	replication fork
9.58	3.12e-04	GO:0035098	ESC/E(Z) complex
1.29	4.76e-04	GO:0043234	protein complex
3.65	1.54e-03	GO:0034708	methyltransferase complex
3.65	1.54e-03	GO:0035097	histone methyltransferase complex
6.16	1.61e-03	GO:0030530	heterogeneous nuclear ribonucleoprotein complex
3.38	2.49e-03	GO:0000786	nucleosome
8.21	8.41e-03	GO:0005721	centromeric heterochromatin
1.65	2.16e-02	GO:0005730	nucleolus

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.57	1.50e-20	GO:0003676	nucleic acid binding
1.58	1.97e-13	GO:0003677	DNA binding
1.25	8.88e-13	GO:0005515	protein binding
1.12	1.47e-10	GO:0005488	binding
1.67	2.25e-06	GO:0001071	nucleic acid binding transcription factor activity
1.67	2.25e-06	GO:0003700	sequence-specific DNA binding transcription factor activity
1.40	4.47e-06	GO:0000166	nucleotide binding
1.62	3.33e-04	GO:0003723	RNA binding
1.52	1.20e-03	GO:0030528	transcription regulator activity
1.63	2.18e-03	GO:0043565	sequence-specific DNA binding
1.82	7.94e-03	GO:0003712	transcription cofactor activity
1.81	8.59e-03	GO:0000988	protein binding transcription factor activity
1.81	8.59e-03	GO:0000989	transcription factor binding transcription factor activity
2.20	8.65e-03	GO:0043566	structure-specific DNA binding
3.24	2.18e-02	GO:0003697	single-stranded DNA binding