Motif ID: EHF.p2

Z-value: 2.151


Transcription factors associated with EHF.p2:

Gene SymbolEntrez IDGene Name
EHF 26298 ets homologous factor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
EHFchr11_+_345992270.581.9e-02Click!


Activity profile for motif EHF.p2.

activity profile for motif EHF.p2


Sorted Z-values histogram for motif EHF.p2

Sorted Z-values for motif EHF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EHF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_+_44937025 2.605 NM_031431
COG3
component of oligomeric golgi complex 3
chr15_-_62435267 1.639 CSNK1G1
casein kinase 1, gamma 1
chr1_-_28842103 1.561 NM_001135218
NM_005644
TAF12

TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa

chr15_-_62435412 1.534 NM_022048
CSNK1G1
casein kinase 1, gamma 1
chr2_-_43676603 1.527 NM_001083953
NM_022065
THADA

thyroid adenoma associated

chr2_-_45691887 1.506 NM_018079
SRBD1
S1 RNA binding domain 1
chr1_-_9925908 1.437 LZIC
leucine zipper and CTNNBIP1 domain containing
chr1_-_28287658 1.299 NM_001990
EYA3
eyes absent homolog 3 (Drosophila)
chr6_+_36961617 1.270 NM_152734
C6orf89
chromosome 6 open reading frame 89
chr1_+_9926072 1.251 NM_022787
NMNAT1
nicotinamide nucleotide adenylyltransferase 1
chr6_-_7334940 1.246 NM_001170692
NM_001170693
NM_205864
CAGE1


cancer antigen 1


chr19_+_63386193 1.243 NM_016324
NM_016325
NM_133502
ZNF274


zinc finger protein 274


chr22_+_20350272 1.230 NM_014337
NM_148175
NM_148176
PPIL2


peptidylprolyl isomerase (cyclophilin)-like 2


chr12_+_67366989 1.206 NM_020401
NUP107
nucleoporin 107kDa
chr1_+_44451698 1.194 NM_001034023
NM_001034024
NM_019100
DMAP1


DNA methyltransferase 1 associated protein 1


chr17_-_53420595 1.159 NM_007146
VEZF1
vascular endothelial zinc finger 1
chr2_+_113058470 1.149 NM_032309
CHCHD5
coiled-coil-helix-coiled-coil-helix domain containing 5
chr17_-_30929669 1.077 NM_000286
PEX12
peroxisomal biogenesis factor 12
chr15_-_62173041 1.067 NM_001014812
NM_032231
FAM96A

family with sequence similarity 96, member A

chr10_-_79459170 1.047 POLR3A
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr1_+_173235193 1.046 NM_001007214
CACYBP
calcyclin binding protein
chr19_-_4674754 1.045 DPP9
dipeptidyl-peptidase 9
chr12_-_121780835 1.032 NM_032554
GPR81
G protein-coupled receptor 81
chr1_-_43523825 1.030 NM_182517
NM_001164829
C1orf210

chromosome 1 open reading frame 210

chr12_-_32940931 1.020 NM_001005242
NM_004572
PKP2

plakophilin 2

chr9_-_114520184 0.999 NM_021218
C9orf80
chromosome 9 open reading frame 80
chr3_-_120878910 0.996 NM_005694
COX17
COX17 cytochrome c oxidase assembly homolog (S. cerevisiae)
chr19_-_4674791 0.984 DPP9
dipeptidyl-peptidase 9
chr22_-_28279643 0.961 NM_001002878
NM_001002879
NM_001002877
NM_003678
THOC5



THO complex 5



chr19_+_40431618 0.961 LSR
lipolysis stimulated lipoprotein receptor
chr1_+_9926113 0.956 NMNAT1
nicotinamide nucleotide adenylyltransferase 1
chr9_-_114520118 0.949 C9orf80
chromosome 9 open reading frame 80
chr6_+_7335011 0.944 NM_031480
RIOK1
RIO kinase 1 (yeast)
chr6_-_31728447 0.926 NM_004639
NM_080702
NM_080703
BAG6


BCL2-associated athanogene 6


chr20_+_43425153 0.904 NM_001099791
NM_033542
SYS1-DBNDD2
SYS1

SYS1-DBNDD2 read-through transcript
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)

chr1_+_202097346 0.899 SNRPE
small nuclear ribonucleoprotein polypeptide E
chr11_-_9292694 0.889 TMEM41B
transmembrane protein 41B
chr6_-_31728418 0.888 BAG6
BCL2-associated athanogene 6
chr19_+_57592913 0.887 NM_032423
ZNF528
zinc finger protein 528
chr19_-_4674814 0.883 NM_139159
DPP9
dipeptidyl-peptidase 9
chr3_-_47299259 0.879 NM_001134878
NM_022342
NM_182902
KIF9


kinesin family member 9


chr1_+_39229474 0.874 NM_001136275
NM_024595
AKIRIN1

akirin 1

chr15_-_40236061 0.867 NM_213600
PLA2G4F
phospholipase A2, group IVF
chr6_-_116488458 0.859 NM_002031
FRK
fyn-related kinase
chr12_-_48248132 0.845 NM_006337
MCRS1
microspherule protein 1
chr1_+_202097355 0.834 NM_003094
SNRPE
small nuclear ribonucleoprotein polypeptide E
chr1_+_196392513 0.823 NM_133494
NEK7
NIMA (never in mitosis gene a)-related kinase 7
chr7_+_107171809 0.812 CBLL1
Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1
chr1_+_202097386 0.811 SNRPE
small nuclear ribonucleoprotein polypeptide E
chr13_-_113151453 0.811 NM_199162
ADPRHL1
ADP-ribosylhydrolase like 1
chr14_+_22411200 0.807 LRP10
low density lipoprotein receptor-related protein 10
chr9_+_130173418 0.804 NM_001135947
NM_030914
URM1

ubiquitin related modifier 1

chr11_-_9292737 0.801 NM_001165030
NM_015012
TMEM41B

transmembrane protein 41B

chr16_-_28843955 0.794 NM_024816
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr1_-_202449659 0.792 NM_198447
GOLT1A
golgi transport 1A
chr5_+_140719773 0.789 NM_018923
NM_032096
PCDHGB2

protocadherin gamma subfamily B, 2

chr6_-_31728405 0.783 BAG6
BCL2-associated athanogene 6
chr6_-_31728363 0.772 BAG6
BCL2-associated athanogene 6
chr8_-_144887876 0.772 NM_198488
FAM83H
family with sequence similarity 83, member H
chr1_-_234834410 0.758 NM_018072
HEATR1
HEAT repeat containing 1
chr1_-_71319559 0.753 NM_005455
NM_203350
ZRANB2

zinc finger, RAN-binding domain containing 2

chr7_-_72063147 0.746 NSUN5P2
NOP2/Sun domain family, member 5 pseudogene 2
chr2_+_138975946 0.746


chr19_-_12653676 0.738 NM_001930
NM_013406
NM_013407
DHPS


deoxyhypusine synthase


chr3_-_134863316 0.717 NM_007027
TOPBP1
topoisomerase (DNA) II binding protein 1
chr19_-_57592778 0.714 LOC284373
hypothetical protein LOC284373
chr11_-_9292581 0.714 TMEM41B
transmembrane protein 41B
chr1_+_149638633 0.702 NM_002796
PSMB4
proteasome (prosome, macropain) subunit, beta type, 4
chr16_-_8798973 0.701 NM_015421
TMEM186
transmembrane protein 186
chr11_+_73559900 0.699 PPME1
protein phosphatase methylesterase 1
chr7_+_39956128 0.698 CDK13
cyclin-dependent kinase 13
chr1_-_25431544 0.696 NM_015484
NM_207170
SYF2

SYF2 homolog, RNA splicing factor (S. cerevisiae)

chr19_-_1556400 0.692 UQCR11
ubiquinol-cytochrome c reductase, complex III subunit XI
chr10_+_75174151 0.685 SEC24C
SEC24 family, member C (S. cerevisiae)
chr19_-_12653698 0.684 DHPS
deoxyhypusine synthase
chr19_+_63022879 0.683 LOC100293516
zinc finger protein
chr9_+_130173458 0.683 URM1
ubiquitin related modifier 1
chr15_-_89366483 0.679


chr5_+_158622843 0.679 UBLCP1
ubiquitin-like domain containing CTD phosphatase 1
chr11_-_63841556 0.678 NM_016404
TRMT112
tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr19_-_1556462 0.677 UQCR11
ubiquinol-cytochrome c reductase, complex III subunit XI
chr6_-_31618203 0.676 NM_004640
NM_080598
DDX39B

DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B

chr12_+_42439026 0.674 IRAK4
interleukin-1 receptor-associated kinase 4
chr1_-_152797820 0.674 UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr15_+_94676691 0.669 NM_001145156
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr10_+_75174125 0.668 NM_004922
NM_198597
SEC24C

SEC24 family, member C (S. cerevisiae)

chr17_-_43263859 0.664 NM_145255
NM_148887
MRPL10

mitochondrial ribosomal protein L10

chr1_-_71319265 0.661 ZRANB2
zinc finger, RAN-binding domain containing 2
chr19_+_40431359 0.657 NM_015925
NM_205834
NM_205835
LSR


lipolysis stimulated lipoprotein receptor


chr1_+_199130571 0.656 NM_001142569
C1orf106
chromosome 1 open reading frame 106
chr19_-_1556464 0.656 NM_006830
UQCR11
ubiquinol-cytochrome c reductase, complex III subunit XI
chr6_+_33276580 0.652 NM_001077516
NM_006979
SLC39A7

solute carrier family 39 (zinc transporter), member 7

chr17_-_55139538 0.646 NM_016077
PTRH2
peptidyl-tRNA hydrolase 2
chr21_-_45046090 0.642 NM_003343
NM_182688
UBE2G2

ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast)

chr17_-_76883677 0.637 NM_001037984
NM_138570
SLC38A10

solute carrier family 38, member 10

chr6_-_31728121 0.636 NM_001098534
BAG6
BCL2-associated athanogene 6
chr19_-_45416043 0.629 TTC9B
tetratricopeptide repeat domain 9B
chr5_-_102926349 0.623 NM_031438
NUDT12
nudix (nucleoside diphosphate linked moiety X)-type motif 12
chr19_+_40431122 0.618 LSR
lipolysis stimulated lipoprotein receptor
chr1_+_159438798 0.616 NDUFS2
NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
chr11_+_73559964 0.613 NM_016147
PPME1
protein phosphatase methylesterase 1
chr1_-_152797760 0.613 UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr3_-_46224791 0.608 NM_001295
CCR1
chemokine (C-C motif) receptor 1
chr7_-_97439573 0.607 MGC72080
MGC72080 pseudogene
chr16_+_30993223 0.607 NM_014699
ZNF646
zinc finger protein 646
chr17_+_37340401 0.604 NM_031421
TTC25
tetratricopeptide repeat domain 25
chr1_-_152797767 0.602 UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr19_-_14543811 0.602 NM_004146
NDUFB7
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
chr19_-_12653577 0.591 DHPS
deoxyhypusine synthase
chr6_-_166675980 0.589 NM_145169
SFT2D1
SFT2 domain containing 1
chr19_+_62483093 0.587 ZNF460
zinc finger protein 460
chr7_-_97439590 0.586


chr9_+_129588179 0.584 CDK9
cyclin-dependent kinase 9
chr6_-_36950520 0.579 PPIL1
peptidylprolyl isomerase (cyclophilin)-like 1
chr7_+_98994363 0.579 NM_001009958
NM_001009960
NM_001085367
NM_001085368
ZNF655



zinc finger protein 655



chr16_-_70400232 0.579 AP1G1
adaptor-related protein complex 1, gamma 1 subunit
chr2_-_122210873 0.579 NM_032390
MKI67IP
MKI67 (FHA domain) interacting nucleolar phosphoprotein
chr15_+_43667050 0.577 PLDN
pallidin homolog (mouse)
chr2_+_101235695 0.575 NM_017546
C2orf29
chromosome 2 open reading frame 29
chr4_-_103968104 0.572 NM_003340
NM_181886
NM_181888
NM_181889
UBE2D3



ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)



chr2_-_27147995 0.572 NM_001134693
OST4
oligosaccharyltransferase 4 homolog (S. cerevisiae)
chr5_+_177490624 0.571 NM_022762
RMND5B
required for meiotic nuclear division 5 homolog B (S. cerevisiae)
chr1_-_149245503 0.567 NM_001163259
NM_001163260
NM_001040217
FAM63A


family with sequence similarity 63, member A


chr12_+_42439013 0.567 NM_001114182
NM_001145256
NM_001145257
NM_001145258
NM_016123
IRAK4




interleukin-1 receptor-associated kinase 4




chr6_-_28475478 0.565 NM_001163391
ZSCAN12
zinc finger and SCAN domain containing 12
chr19_+_16157198 0.565 NM_014077
FAM32A
family with sequence similarity 32, member A
chrX_-_131179598 0.563 NM_021183
RAP2C
RAP2C, member of RAS oncogene family
chr1_+_23890880 0.560 NM_000975
RPL11
ribosomal protein L11
chr1_+_229731021 0.560 NM_005999
TSNAX-DISC1
TSNAX
TSNAX-DISC1 read-through gene
translin-associated factor X
chr11_+_43336979 0.557 NM_018259
TTC17
tetratricopeptide repeat domain 17
chr2_+_101235782 0.553 C2orf29
chromosome 2 open reading frame 29
chr14_+_23771464 0.552 NM_001002000
NM_001002001
GMPR2

guanosine monophosphate reductase 2

chr1_+_159438810 0.549 NDUFS2
NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
chr6_-_43054918 0.548 NM_000287
PEX6
peroxisomal biogenesis factor 6
chr1_+_159438787 0.548 NDUFS2
NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
chr5_+_177490614 0.543 RMND5B
required for meiotic nuclear division 5 homolog B (S. cerevisiae)
chr6_-_43054865 0.541 PEX6
peroxisomal biogenesis factor 6
chr1_-_52642646 0.538 NM_001190818
NM_001190819
NM_004153
ORC1


origin recognition complex, subunit 1


chr2_+_128565269 0.536 UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
chr9_+_126671209 0.536 ARPC5L
actin related protein 2/3 complex, subunit 5-like
chr2_+_187162969 0.535 NM_001145000
NM_002210
ITGAV

integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)

chr19_+_13746278 0.532 C19orf53
chromosome 19 open reading frame 53
chr15_+_21361901 0.531 MKRN3
makorin ring finger protein 3
chr17_-_77602938 0.530 NM_002917
RFNG
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr1_+_23890857 0.527 RPL11
ribosomal protein L11
chr19_-_2901583 0.521


chr15_-_53276420 0.520 NM_016304
RSL24D1
ribosomal L24 domain containing 1
chrX_-_7855400 0.517 NM_004650
PNPLA4
patatin-like phospholipase domain containing 4
chr8_+_144888275 0.516 LOC100128338
hypothetical LOC100128338
chr1_+_37712767 0.516 ZC3H12A
zinc finger CCCH-type containing 12A
chr13_+_30089829 0.515 NM_005800
USPL1
ubiquitin specific peptidase like 1
chr20_+_49008754 0.515 NM_014484
MOCS3
molybdenum cofactor synthesis 3
chr1_-_247086686 0.514 NM_030645
SH3BP5L
SH3-binding domain protein 5-like
chr18_+_20260603 0.514 NM_018439
IMPACT
Impact homolog (mouse)
chr1_-_20707196 0.514 NM_024544
MUL1
mitochondrial E3 ubiquitin protein ligase 1
chr2_+_128565222 0.513 NM_020120
UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
chr2_+_113058642 0.511 CHCHD5
coiled-coil-helix-coiled-coil-helix domain containing 5
chr17_+_77603064 0.507 GPS1
G protein pathway suppressor 1
chr15_-_53276354 0.507 RSL24D1
ribosomal L24 domain containing 1
chr9_+_126671297 0.507 NM_030978
ARPC5L
actin related protein 2/3 complex, subunit 5-like
chr14_+_77244191 0.506 C14orf156
chromosome 14 open reading frame 156
chr15_+_88609837 0.504 NM_001033088
NGRN
neugrin, neurite outgrowth associated
chr19_+_53641053 0.504 GRWD1
glutamate-rich WD repeat containing 1
chr21_-_44784499 0.502 NM_198691
KRTAP10-1
keratin associated protein 10-1
chr2_+_118288754 0.502 DDX18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr20_-_2399355 0.502 SNRPB
small nuclear ribonucleoprotein polypeptides B and B1
chr19_+_53641029 0.502 GRWD1
glutamate-rich WD repeat containing 1
chr5_+_132230214 0.500 NM_014402
UQCRQ
ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa
chr19_+_13746255 0.500 NM_014047
C19orf53
chromosome 19 open reading frame 53
chr14_+_77244177 0.500 NM_031210
C14orf156
chromosome 14 open reading frame 156
chr17_-_78001981 0.500 NM_001033046
NM_001100407
NM_001100408
NM_001193653
NM_001193654
NM_001193657
C17orf62





chromosome 17 open reading frame 62





chr7_-_91713044 0.497 NM_004912
NM_001013406
NM_194454
KRIT1


KRIT1, ankyrin repeat containing


chr22_-_19543069 0.496 NM_058004
PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr9_-_126217510 0.496 NM_002799
PSMB7
proteasome (prosome, macropain) subunit, beta type, 7
chr11_+_73560088 0.495 PPME1
protein phosphatase methylesterase 1
chr20_+_36534871 0.494 NM_020336
RALGAPB
Ral GTPase activating protein, beta subunit (non-catalytic)
chr19_+_1358664 0.493 DAZAP1
DAZ associated protein 1
chr9_+_132990834 0.493 NUP214
nucleoporin 214kDa
chr1_+_31654998 0.492 NM_001199038
SERINC2
serine incorporator 2
chr2_+_232359303 0.491 NM_022730
COPS7B
COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis)
chr6_+_126282078 0.491 NCOA7
nuclear receptor coactivator 7
chr11_-_64641700 0.488 NM_014205
ZNHIT2
zinc finger, HIT-type containing 2
chr16_-_70400040 0.487 AP1G1
adaptor-related protein complex 1, gamma 1 subunit
chr1_+_42896634 0.486 NM_006347
PPIH
peptidylprolyl isomerase H (cyclophilin H)
chr19_-_1966628 0.481 NM_017797
BTBD2
BTB (POZ) domain containing 2
chr5_+_177490582 0.480 RMND5B
required for meiotic nuclear division 5 homolog B (S. cerevisiae)
chr6_+_31190505 0.479 NM_014068
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr11_-_71501385 0.477 NM_014042
C11orf51
chromosome 11 open reading frame 51
chr6_-_166676016 0.475 SFT2D1
SFT2 domain containing 1
chr14_-_77244073 0.475 NM_006020
ALKBH1
alkB, alkylation repair homolog 1 (E. coli)
chr4_-_9727598 0.473 NM_005112
NM_017491
WDR1

WD repeat domain 1

chrX_+_46938178 0.472 UBA1
ubiquitin-like modifier activating enzyme 1
chr17_-_24163517 0.472 C17orf63
chromosome 17 open reading frame 63
chr1_+_23990228 0.471 NM_007260
LYPLA2
lysophospholipase II
chr17_+_77603028 0.471 NM_004127
NM_212492
GPS1

G protein pathway suppressor 1

chr2_+_170259195 0.468 NM_144711
NM_001008489
PHOSPHO2-KLHL23
KLHL23
PHOSPHO2
PHOSPHO2-KLHL23 read-through transcript
kelch-like 23 (Drosophila)
phosphatase, orphan 2
chr14_-_38709161 0.466 NM_001079537
NM_177452
TRAPPC6B

trafficking protein particle complex 6B

chr9_+_132990760 0.464 NM_005085
NUP214
nucleoporin 214kDa
chrX_+_46938215 0.463 UBA1
ubiquitin-like modifier activating enzyme 1
chr1_-_19684652 0.459 NM_004930
CAPZB
capping protein (actin filament) muscle Z-line, beta

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.34 1.23e-21 GO:0044260 cellular macromolecule metabolic process
1.27 1.50e-16 GO:0043170 macromolecule metabolic process
1.42 6.04e-14 GO:0090304 nucleic acid metabolic process
1.45 6.96e-13 GO:0010467 gene expression
1.20 8.06e-13 GO:0044237 cellular metabolic process
1.38 9.41e-13 GO:0044267 cellular protein metabolic process
1.35 1.36e-12 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.45 1.51e-11 GO:0016070 RNA metabolic process
1.63 2.21e-10 GO:0015031 protein transport
1.92 6.03e-10 GO:0016032 viral reproduction
1.55 7.70e-10 GO:0008104 protein localization
1.61 7.75e-10 GO:0045184 establishment of protein localization
1.63 4.32e-09 GO:0046907 intracellular transport
1.70 4.87e-09 GO:0006396 RNA processing
1.17 5.39e-09 GO:0044238 primary metabolic process
2.30 7.02e-09 GO:0022613 ribonucleoprotein complex biogenesis
1.15 1.05e-08 GO:0008152 metabolic process
1.27 1.45e-08 GO:0034641 cellular nitrogen compound metabolic process
1.75 1.74e-08 GO:0016071 mRNA metabolic process
1.68 3.74e-08 GO:0009057 macromolecule catabolic process
1.74 5.25e-08 GO:0044265 cellular macromolecule catabolic process
1.29 7.42e-08 GO:0071841 cellular component organization or biogenesis at cellular level
1.39 8.42e-08 GO:0034645 cellular macromolecule biosynthetic process
2.18 1.16e-07 GO:0071843 cellular component biogenesis at cellular level
1.44 1.21e-07 GO:0033036 macromolecule localization
1.25 1.61e-07 GO:0006807 nitrogen compound metabolic process
1.37 2.48e-07 GO:0009059 macromolecule biosynthetic process
1.24 2.91e-07 GO:0071840 cellular component organization or biogenesis
1.93 3.06e-07 GO:0006412 translation
1.85 4.67e-07 GO:0030163 protein catabolic process
1.26 5.42e-07 GO:0019538 protein metabolic process
1.88 8.16e-07 GO:0051603 proteolysis involved in cellular protein catabolic process
1.86 1.11e-06 GO:0044257 cellular protein catabolic process
1.42 1.31e-06 GO:0051641 cellular localization
1.87 2.22e-06 GO:0019941 modification-dependent protein catabolic process
1.93 2.91e-06 GO:0032446 protein modification by small protein conjugation
1.86 3.24e-06 GO:0043632 modification-dependent macromolecule catabolic process
1.87 3.81e-06 GO:0006511 ubiquitin-dependent protein catabolic process
1.44 4.43e-06 GO:0051649 establishment of localization in cell
1.95 6.11e-06 GO:0016567 protein ubiquitination
2.37 9.54e-06 GO:0042254 ribosome biogenesis
2.07 1.26e-05 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.07 1.26e-05 GO:0000398 nuclear mRNA splicing, via spliceosome
2.05 1.54e-05 GO:0000375 RNA splicing, via transesterification reactions
1.84 1.62e-05 GO:0008380 RNA splicing
1.34 1.92e-05 GO:0006996 organelle organization
1.80 1.98e-05 GO:0070647 protein modification by small protein conjugation or removal
1.25 2.42e-05 GO:0071842 cellular component organization at cellular level
1.51 2.77e-05 GO:0016192 vesicle-mediated transport
1.21 1.23e-04 GO:0016043 cellular component organization
1.82 1.64e-04 GO:0010608 posttranscriptional regulation of gene expression
1.68 2.11e-04 GO:0006397 mRNA processing
1.57 5.12e-04 GO:0006974 response to DNA damage stimulus
1.27 6.26e-04 GO:0043412 macromolecule modification
1.56 6.54e-04 GO:0034613 cellular protein localization
1.38 8.85e-04 GO:0007049 cell cycle
1.55 9.39e-04 GO:0070727 cellular macromolecule localization
1.64 9.76e-04 GO:0006886 intracellular protein transport
2.38 1.69e-03 GO:0071826 ribonucleoprotein complex subunit organization
1.99 1.78e-03 GO:0010498 proteasomal protein catabolic process
1.99 1.78e-03 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
1.34 1.94e-03 GO:0044085 cellular component biogenesis
1.55 2.28e-03 GO:0034621 cellular macromolecular complex subunit organization
1.07 4.04e-03 GO:0009987 cellular process
1.82 5.09e-03 GO:0033365 protein localization to organelle
1.26 6.07e-03 GO:0006464 protein modification process
1.22 6.58e-03 GO:0044249 cellular biosynthetic process
2.36 6.92e-03 GO:0000216 M/G1 transition of mitotic cell cycle
2.28 7.48e-03 GO:0030330 DNA damage response, signal transduction by p53 class mediator
1.39 8.27e-03 GO:0043933 macromolecular complex subunit organization
1.29 9.30e-03 GO:0009056 catabolic process
2.12 9.77e-03 GO:0042770 signal transduction in response to DNA damage
2.49 9.89e-03 GO:0071158 positive regulation of cell cycle arrest
2.30 1.28e-02 GO:0022618 ribonucleoprotein complex assembly
1.32 1.43e-02 GO:0044248 cellular catabolic process
1.46 1.44e-02 GO:0000278 mitotic cell cycle
1.38 2.01e-02 GO:0022402 cell cycle process
2.07 2.04e-02 GO:0051320 S phase
2.32 2.17e-02 GO:0000209 protein polyubiquitination
2.28 2.24e-02 GO:0031575 mitotic cell cycle G1/S transition checkpoint
2.28 2.24e-02 GO:0071779 G1/S transition checkpoint
2.25 2.28e-02 GO:2000045 regulation of G1/S transition of mitotic cell cycle
2.21 2.30e-02 GO:0006415 translational termination
1.62 2.66e-02 GO:0051325 interphase
2.07 2.69e-02 GO:0032984 macromolecular complex disassembly
2.07 2.69e-02 GO:0034623 cellular macromolecular complex disassembly
2.11 2.87e-02 GO:0006414 translational elongation
2.22 3.02e-02 GO:0019080 viral genome expression
2.22 3.02e-02 GO:0019083 viral transcription
1.37 3.13e-02 GO:0033554 cellular response to stress
2.05 3.41e-02 GO:0000084 S phase of mitotic cell cycle
1.20 3.54e-02 GO:0009058 biosynthetic process
2.35 3.68e-02 GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint
2.35 3.68e-02 GO:0072594 establishment of protein localization to organelle
2.42 4.51e-02 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
2.42 4.51e-02 GO:0072395 signal transduction involved in cell cycle checkpoint
2.42 4.51e-02 GO:0072401 signal transduction involved in DNA integrity checkpoint
2.42 4.51e-02 GO:0072404 signal transduction involved in G1/S transition checkpoint
2.42 4.51e-02 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint
2.42 4.51e-02 GO:0072422 signal transduction involved in DNA damage checkpoint
2.42 4.51e-02 GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
2.42 4.51e-02 GO:0072474 signal transduction involved in mitotic cell cycle G1/S checkpoint
1.64 4.68e-02 GO:0034660 ncRNA metabolic process
1.61 4.90e-02 GO:0051329 interphase of mitotic cell cycle
1.77 4.99e-02 GO:0022411 cellular component disassembly
1.77 4.99e-02 GO:0071845 cellular component disassembly at cellular level

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.19 4.14e-46 GO:0044424 intracellular part
1.18 1.73e-45 GO:0005622 intracellular
1.22 1.10e-40 GO:0043229 intracellular organelle
1.22 1.48e-40 GO:0043226 organelle
1.24 1.48e-38 GO:0043231 intracellular membrane-bounded organelle
1.24 1.91e-38 GO:0043227 membrane-bounded organelle
1.32 2.76e-29 GO:0044446 intracellular organelle part
1.31 3.76e-28 GO:0044422 organelle part
1.31 1.41e-27 GO:0005634 nucleus
1.54 1.26e-24 GO:0044428 nuclear part
1.47 3.27e-20 GO:0031974 membrane-enclosed lumen
1.54 8.04e-20 GO:0031981 nuclear lumen
1.47 1.08e-19 GO:0070013 intracellular organelle lumen
1.47 2.04e-19 GO:0043233 organelle lumen
1.18 5.56e-18 GO:0005737 cytoplasm
1.98 4.69e-16 GO:0030529 ribonucleoprotein complex
1.32 5.70e-16 GO:0032991 macromolecular complex
1.21 2.84e-14 GO:0044444 cytoplasmic part
1.49 2.00e-11 GO:0005654 nucleoplasm
1.30 6.03e-10 GO:0043228 non-membrane-bounded organelle
1.30 6.03e-10 GO:0043232 intracellular non-membrane-bounded organelle
1.34 6.20e-09 GO:0005829 cytosol
1.65 9.38e-07 GO:0005730 nucleolus
1.23 4.09e-06 GO:0043234 protein complex
2.16 2.24e-05 GO:0000151 ubiquitin ligase complex
1.26 3.27e-05 GO:0031090 organelle membrane
2.17 3.86e-05 GO:0005681 spliceosomal complex
1.47 4.53e-05 GO:0044451 nucleoplasm part
1.91 2.42e-04 GO:0005840 ribosome
1.03 6.35e-04 GO:0044464 cell part
1.03 6.66e-04 GO:0005623 cell
2.44 4.29e-03 GO:0000502 proteasome complex
2.25 5.12e-03 GO:0071013 catalytic step 2 spliceosome
1.44 5.49e-03 GO:0005694 chromosome
2.33 1.12e-02 GO:0030117 membrane coat
2.33 1.12e-02 GO:0048475 coated membrane
1.67 1.38e-02 GO:0016604 nuclear body
1.36 2.11e-02 GO:0031967 organelle envelope
1.29 3.75e-02 GO:0005794 Golgi apparatus
1.86 4.55e-02 GO:0016607 nuclear speck

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.17 3.19e-13 GO:0005515 protein binding
1.28 3.93e-11 GO:0003676 nucleic acid binding
1.60 6.42e-10 GO:0003723 RNA binding
1.08 1.06e-08 GO:0005488 binding
1.85 1.24e-05 GO:0016881 acid-amino acid ligase activity
1.84 1.24e-04 GO:0019787 small conjugating protein ligase activity
1.87 1.31e-04 GO:0004842 ubiquitin-protein ligase activity
1.73 1.77e-04 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.56 4.70e-04 GO:0016874 ligase activity
1.91 5.05e-03 GO:0003735 structural constituent of ribosome
2.70 2.49e-02 GO:0043021 ribonucleoprotein binding
1.20 2.92e-02 GO:0008270 zinc ion binding