Motif ID: FOXD3.p2

Z-value: 1.124


Transcription factors associated with FOXD3.p2:

Gene SymbolEntrez IDGene Name
FOXD3 27022 forkhead box D3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXD3chr1_+_635616320.562.3e-02Click!


Activity profile for motif FOXD3.p2.

activity profile for motif FOXD3.p2


Sorted Z-values histogram for motif FOXD3.p2

Sorted Z-values for motif FOXD3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXD3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_151284396 2.954 NM_145292
GALNTL5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5
chr2_+_37282516 2.787 LOC100505876
hypothetical LOC100505876
chr1_-_77457664 2.037 NM_005482
PIGK
phosphatidylinositol glycan anchor biosynthesis, class K
chr7_-_87687276 1.955 SRI
sorcin
chr19_-_4782711 1.810 NM_182919
TICAM1
toll-like receptor adaptor molecule 1
chr22_-_45037882 1.769 NM_006071
PKDREJ
polycystic kidney disease (polycystin) and REJ homolog (sperm receptor for egg jelly homolog, sea urchin)
chr10_-_31328426 1.578 NM_001143769
ZNF438
zinc finger protein 438
chr4_+_89519004 1.527 HERC6
hect domain and RLD 6
chr8_+_67201684 1.350 NM_033058
NM_184085
NM_184086
NM_184087
TRIM55



tripartite motif containing 55



chr7_-_87687302 1.315 NM_003130
SRI
sorcin
chr3_-_184756101 1.305 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr5_+_159368721 1.270 TTC1
tetratricopeptide repeat domain 1
chr9_+_101717278 1.266 STX17
syntaxin 17
chr5_+_159368690 1.199 TTC1
tetratricopeptide repeat domain 1
chr19_+_12995782 1.196 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr4_+_89518898 1.112 NM_001165136
NM_017912
HERC6

hect domain and RLD 6

chr5_+_159368733 1.102 NM_003314
TTC1
tetratricopeptide repeat domain 1
chr7_-_102070473 1.098 NM_001114403
UPK3BL
POLR2J2
uroplakin 3B-like
polymerase (RNA) II (DNA directed) polypeptide J2
chr12_+_111375382 1.078 PTPN11
protein tyrosine phosphatase, non-receptor type 11
chr3_+_108578877 1.056 NM_032600
CCDC54
coiled-coil domain containing 54
chr19_+_57564981 1.053 NM_001145434
ZNF880
zinc finger protein 880
chr19_+_41177882 1.050 NM_001042631
SDHAF1
succinate dehydrogenase complex assembly factor 1
chr8_-_108579270 1.003 NM_001146
ANGPT1
angiopoietin 1
chr19_-_23248804 0.979 LOC100132815
hypothetical LOC100132815
chr22_-_23500682 0.932 NM_001008496
PIWIL3
piwi-like 3 (Drosophila)
chr19_-_56946911 0.913 NM_001193306
NM_002029
FPR1

formyl peptide receptor 1

chr5_-_114543632 0.909 NM_001017397
NM_001017398
NM_018700
TRIM36


tripartite motif containing 36


chr4_-_123596921 0.865 NM_000586
IL2
interleukin 2
chr7_+_28418668 0.861 NM_182898
CREB5
cAMP responsive element binding protein 5
chr1_+_84402962 0.858 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr4_-_153523113 0.836 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr4_-_38710376 0.828 NM_024943
TMEM156
transmembrane protein 156
chr4_-_186815116 0.813 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr3_-_188339882 0.805 NM_052969
RPL39L
ribosomal protein L39-like
chr11_+_67107852 0.802 GSTP1
glutathione S-transferase pi 1
chr1_-_8799966 0.793 NM_001042681
NM_012102
RERE

arginine-glutamic acid dipeptide (RE) repeats

chr18_-_21184824 0.781


chr3_+_38238080 0.777 OXSR1
oxidative-stress responsive 1
chr6_+_74228331 0.769 MTO1
mitochondrial translation optimization 1 homolog (S. cerevisiae)
chr12_-_120591938 0.764 NM_173855
MORN3
MORN repeat containing 3
chr7_-_112513379 0.764 NM_001146266
NM_001146267
GPR85

G protein-coupled receptor 85

chr4_-_186814852 0.757 SORBS2
sorbin and SH3 domain containing 2
chr9_-_87904844 0.754 NM_177937
GOLM1
golgi membrane protein 1
chr1_-_67366807 0.747 NM_001013674
C1orf141
chromosome 1 open reading frame 141
chr7_+_75928907 0.721 NM_001102594
NM_001102595
NM_020892
DTX2


deltex homolog 2 (Drosophila)


chr5_-_158459006 0.717 EBF1
early B-cell factor 1
chr15_-_38953628 0.714 NM_133639
RHOV
ras homolog gene family, member V
chr10_-_921694 0.711 NM_015155
LARP4B
La ribonucleoprotein domain family, member 4B
chr5_-_158459276 0.700 NM_024007
EBF1
early B-cell factor 1
chr7_-_16471817 0.669 NM_015464
SOSTDC1
sclerostin domain containing 1
chr3_-_127810087 0.668 NM_001039783
TXNRD3IT1
thioredoxin reductase 3 intronic transcript 1
chr12_-_41163680 0.656 NM_001144881
PRICKLE1
prickle homolog 1 (Drosophila)
chr8_+_75066117 0.649 NM_001195797
NM_015364
LY96

lymphocyte antigen 96

chr16_+_24648446 0.644 NM_014494
TNRC6A
trinucleotide repeat containing 6A
chr14_-_60817946 0.634


chr15_-_63108974 0.624 NM_139242
MTFMT
mitochondrial methionyl-tRNA formyltransferase
chr12_-_120219941 0.623 CAMKK2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr17_-_31219943 0.616 NM_152781
C17orf66
chromosome 17 open reading frame 66
chr15_-_58477407 0.610 NM_001002857
NM_001002858
NM_001136015
NM_004039
ANXA2



annexin A2



chr1_+_15637521 0.610 NM_007272
CTRC
chymotrypsin C (caldecrin)
chr2_+_237143118 0.607 NM_020311
CXCR7
chemokine (C-X-C motif) receptor 7
chr12_+_46799279 0.603 NM_000289
PFKM
phosphofructokinase, muscle
chr9_+_123123364 0.601 GSN
gelsolin
chr3_+_138159396 0.588 NM_144717
IL20RB
interleukin 20 receptor beta
chr21_+_34112456 0.577 ITSN1
intersectin 1 (SH3 domain protein)
chr4_-_103485600 0.576 NM_001135146
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr4_+_119174947 0.570 NM_004784
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr7_+_28441758 0.570 NM_004904
CREB5
cAMP responsive element binding protein 5
chr13_-_98757634 0.569 NM_004951
GPR183
G protein-coupled receptor 183
chr12_+_47584159 0.567 NM_033124
CCDC65
coiled-coil domain containing 65
chr11_+_67107641 0.554 NM_000852
GSTP1
glutathione S-transferase pi 1
chr3_+_195336625 0.547 NM_005524
HES1
hairy and enhancer of split 1, (Drosophila)
chr14_-_19252330 0.545 NM_001197287
OR11H2
olfactory receptor, family 11, subfamily H, member 2
chr1_-_27825178 0.545 NM_001042747
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr4_-_90978469 0.542 NM_001146055
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr9_-_90456824 0.541 NM_001100111
LOC286238
hypothetical protein LOC286238
chr3_+_11242666 0.537 NM_001098211
HRH1
histamine receptor H1
chrX_-_77801480 0.536 NM_152694
ZCCHC5
zinc finger, CCHC domain containing 5
chr14_+_101345878 0.534 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr4_-_77176163 0.533 NM_005409
CXCL11
chemokine (C-X-C motif) ligand 11
chr11_+_112763722 0.531 NM_178510
ANKK1
ankyrin repeat and kinase domain containing 1
chr15_-_72981595 0.528 C15orf17
chromosome 15 open reading frame 17
chr9_-_205892 0.524 NM_152569
C9orf66
chromosome 9 open reading frame 66
chr9_-_34387786 0.522 NM_032596
C9orf24
chromosome 9 open reading frame 24
chr4_+_146250978 0.522 ABCE1
ATP-binding cassette, sub-family E (OABP), member 1
chr4_+_35962038 0.518 NM_001170700
DTHD1
death domain containing 1
chr1_-_24112345 0.516 NM_001841
CNR2
cannabinoid receptor 2 (macrophage)
chrX_-_102829621 0.512 NM_001142419
NM_001142420
NM_001142421
NM_001142422
NM_001142427
NM_001142428
NM_001142431
NM_001142432
MORF4L2







mortality factor 4 like 2







chr19_+_14913298 0.502 NM_012377
OR7C2
olfactory receptor, family 7, subfamily C, member 2
chr14_+_91858677 0.502 NM_153648
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr22_-_28114568 0.499 NM_001127
NM_001166019
NM_145730
AP1B1


adaptor-related protein complex 1, beta 1 subunit


chr1_+_6191506 0.498 RNF207
ring finger protein 207
chr22_+_21384862 0.498 IGLV3-21
IGLJ3
IGLC1
immunoglobulin lambda variable 3-21
immunoglobulin lambda joining 3
immunoglobulin lambda constant 1 (Mcg marker)
chr12_-_103846186 0.498 NM_032148
SLC41A2
solute carrier family 41, member 2
chr1_+_246167115 0.498 NM_175911
OR2L13
olfactory receptor, family 2, subfamily L, member 13
chr6_+_26609427 0.494 NM_001732
BTN1A1
butyrophilin, subfamily 1, member A1
chr12_+_53178834 0.493 NM_001184976
NCKAP1L
NCK-associated protein 1-like
chr5_+_34723420 0.492 NM_001145523
RAI14
retinoic acid induced 14
chr19_-_10474767 0.492 NM_203500
KEAP1
kelch-like ECH-associated protein 1
chr1_-_150044365 0.490 NM_001004432
LINGO4
leucine rich repeat and Ig domain containing 4
chr17_-_8004671 0.488 VAMP2
vesicle-associated membrane protein 2 (synaptobrevin 2)
chr3_+_120799411 0.484 NM_015900
PLA1A
phospholipase A1 member A
chr1_+_181421796 0.483 NM_005562
NM_018891
LAMC2

laminin, gamma 2

chr12_-_52868855 0.483 NM_014311
SMUG1
single-strand-selective monofunctional uracil-DNA glycosylase 1
chr7_+_75864755 0.481 NM_007155
ZP3
zona pellucida glycoprotein 3 (sperm receptor)
chr12_-_55979413 0.478


chr1_-_158759606 0.471 NM_001184714
NM_001184715
NM_001184716
NM_052931
SLAMF6



SLAM family member 6



chr12_+_29193399 0.471 FAR2
fatty acyl CoA reductase 2
chr8_-_42742729 0.470 NM_004198
CHRNA6
cholinergic receptor, nicotinic, alpha 6
chr1_-_25164061 0.469 NM_001031680
RUNX3
runt-related transcription factor 3
chr3_-_106903734 0.465 CBLB
Cas-Br-M (murine) ecotropic retroviral transforming sequence b
chr1_-_89437098 0.465 NM_052941
GBP4
guanylate binding protein 4
chr2_-_213723298 0.464 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr15_-_43458247 0.455 NM_001482
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr6_+_134800533 0.453 LOC154092
hypothetical LOC154092
chr17_+_26322168 0.450 RNF135
ring finger protein 135
chr12_+_9871343 0.450 NM_016523
KLRF1
killer cell lectin-like receptor subfamily F, member 1
chr21_+_42697058 0.449 NM_001001895
NM_018961
UBASH3A

ubiquitin associated and SH3 domain containing A

chrX_+_100241453 0.448 NM_006733
CENPI
centromere protein I
chr3_+_49522871 0.446 DAG1
dystroglycan 1 (dystrophin-associated glycoprotein 1)
chr14_+_55148488 0.445 KTN1
kinectin 1 (kinesin receptor)
chr4_+_41309690 0.441 LIMCH1
LIM and calponin homology domains 1
chr10_+_71231693 0.440 COL13A1
collagen, type XIII, alpha 1
chr4_-_56153135 0.438 NM_152401
PDCL2
phosducin-like 2
chr19_+_14352920 0.434 CD97
CD97 molecule
chr8_-_116749382 0.433 TRPS1
trichorhinophalangeal syndrome I
chr1_-_159275334 0.432 TSTD1
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
chr3_-_131948202 0.430 NM_014602
PIK3R4
phosphoinositide-3-kinase, regulatory subunit 4
chr1_-_177378801 0.429 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr10_+_71231649 0.429 NM_001130103
NM_080798
NM_080800
NM_080801
NM_080802
NM_080805
COL13A1





collagen, type XIII, alpha 1





chr19_+_55013315 0.429 NM_030973
MED25
mediator complex subunit 25
chr1_+_179719338 0.427 NM_000721
CACNA1E
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr17_-_8364942 0.427 MYH10
myosin, heavy chain 10, non-muscle
chrX_-_19815370 0.426 SH3KBP1
SH3-domain kinase binding protein 1
chr6_-_87861492 0.426 NM_000735
CGA
glycoprotein hormones, alpha polypeptide
chr4_-_170915602 0.421 NM_017867
C4orf27
chromosome 4 open reading frame 27
chr3_-_64186151 0.420 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr15_+_97009194 0.420 IGF1R
insulin-like growth factor 1 receptor
chr11_+_122214415 0.420 NM_019604
CRTAM
cytotoxic and regulatory T cell molecule
chr7_-_20223467 0.419 NM_182762
MACC1
metastasis associated in colon cancer 1
chr5_-_180009178 0.414 FLT4
fms-related tyrosine kinase 4
chr4_+_3285671 0.413 NM_002926
NM_198229
RGS12

regulator of G-protein signaling 12

chr1_-_7895873 0.409 UTS2
urotensin 2
chr12_+_53177789 0.408 NCKAP1L
NCK-associated protein 1-like
chr5_-_180009150 0.405 FLT4
fms-related tyrosine kinase 4
chrX_-_71709622 0.405 NM_001166418
NM_001166419
NM_001166420
NM_001166422
NM_001166448
NM_018486
HDAC8





histone deacetylase 8





chr4_+_71713324 0.404 NM_031889
ENAM
enamelin
chr16_-_4263056 0.397 TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr1_+_84540921 0.394 NM_001134664
SAMD13
sterile alpha motif domain containing 13
chr16_+_80370400 0.392 PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr1_+_43063817 0.389 NM_018538
ERMAP
erythroblast membrane-associated protein (Scianna blood group)
chr9_+_204816 0.389 DOCK8
dedicator of cytokinesis 8
chr4_+_75393053 0.387 NM_001013442
EPGN
epithelial mitogen homolog (mouse)
chr3_-_155630197 0.387 NM_001038705
GPR149
G protein-coupled receptor 149
chr8_+_144802972 0.385 NM_014789
ZNF623
zinc finger protein 623
chr11_-_32772731 0.384 NM_001008391
CCDC73
coiled-coil domain containing 73
chr7_-_139948780 0.384 NM_015689
DENND2A
DENN/MADD domain containing 2A
chr17_+_26322081 0.383 NM_001184992
NM_032322
NM_197939
RNF135


ring finger protein 135


chr8_+_66744659 0.380 NM_001145838
MTFR1
mitochondrial fission regulator 1
chr18_-_59137488 0.379 NM_000633
NM_000657
BCL2

B-cell CLL/lymphoma 2

chr11_+_60727559 0.379 NM_001079807
PGA3
PGA4
pepsinogen 3, group I (pepsinogen A)
pepsinogen 4, group I (pepsinogen A)
chr6_-_136889302 0.379 MAP7
microtubule-associated protein 7
chrX_-_129099695 0.378 NM_001130846
AIFM1
apoptosis-inducing factor, mitochondrion-associated, 1
chr1_-_151352587 0.377 NM_001014450
SPRR2A
SPRR2F
small proline-rich protein 2A
small proline-rich protein 2F
chr12_+_122508603 0.375 NM_022717
SNRNP35
small nuclear ribonucleoprotein 35kDa (U11/U12)
chr1_+_162795538 0.375 PBX1
pre-B-cell leukemia homeobox 1
chr15_-_70385709 0.374 NM_001172685
CELF6
CUGBP, Elav-like family member 6
chr15_+_62467055 0.373 NM_016213
TRIP4
thyroid hormone receptor interactor 4
chr9_+_130719034 0.373 LRRC8A
leucine rich repeat containing 8 family, member A
chr7_+_77307382 0.373 NM_001127357
NM_001127359
NM_020432
PHTF2


putative homeodomain transcription factor 2


chr8_+_27687821 0.373 NM_001017420
ESCO2
establishment of cohesion 1 homolog 2 (S. cerevisiae)
chr15_+_43102593 0.373 NM_003104
SORD
sorbitol dehydrogenase
chr5_+_140790141 0.373 PCDHGA12
protocadherin gamma subfamily A, 12
chr17_-_53920699 0.373 NM_001080439
HSF5
heat shock transcription factor family member 5
chr19_+_24061717 0.372 NM_203282
ZNF254
zinc finger protein 254
chr8_+_26569709 0.370 DPYSL2
dihydropyrimidinase-like 2
chr13_+_40533622 0.370 NM_007187
WBP4
WW domain binding protein 4 (formin binding protein 21)
chr5_-_180009205 0.370 FLT4
fms-related tyrosine kinase 4
chr4_+_167013859 0.368 NM_012464
TLL1
tolloid-like 1
chr14_-_49932366 0.368 NM_004196
CDKL1
cyclin-dependent kinase-like 1 (CDC2-related kinase)
chr6_+_12825818 0.367 NM_030948
PHACTR1
phosphatase and actin regulator 1
chr1_+_28637247 0.366 NM_023923
PHACTR4
phosphatase and actin regulator 4
chr7_+_28692122 0.365 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr3_+_142175329 0.365 SLC25A36
solute carrier family 25, member 36
chr7_+_120752656 0.364 NM_016087
WNT16
wingless-type MMTV integration site family, member 16
chr22_+_36008511 0.364 CYTH4
cytohesin 4
chr8_+_133060353 0.363 EFR3A
EFR3 homolog A (S. cerevisiae)
chr11_+_57191887 0.363 ZDHHC5
zinc finger, DHHC-type containing 5
chr1_+_84536636 0.361 NM_001010971
SAMD13
sterile alpha motif domain containing 13
chr1_-_155336223 0.360 NM_001004341
ETV3L
ets variant 3-like
chr6_+_34590624 0.359 PACSIN1
protein kinase C and casein kinase substrate in neurons 1
chr1_+_81544432 0.358 LPHN2
latrophilin 2
chr18_+_59405513 0.357 NM_012397
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr19_-_53305825 0.357 NM_001159322
NM_001159323
NM_003706
PLA2G4C


phospholipase A2, group IVC (cytosolic, calcium-independent)


chr15_+_76345577 0.356 NM_001130183
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr9_-_116920232 0.356 NM_002160
TNC
tenascin C
chr13_-_36471474 0.355 NM_001142364
NM_013338
ALG5

asparagine-linked glycosylation 5, dolichyl-phosphate beta-glucosyltransferase homolog (S. cerevisiae)

chr12_-_55295628 0.353 BAZ2A
bromodomain adjacent to zinc finger domain, 2A
chr6_+_136214495 0.352 NM_018945
PDE7B
phosphodiesterase 7B
chr1_-_171442937 0.352 NM_003326
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.14 2.75e-03 GO:0032501 multicellular organismal process
1.58 6.47e-03 GO:0007608 sensory perception of smell
1.50 3.23e-02 GO:0007606 sensory perception of chemical stimulus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.16 2.85e-04 GO:0005886 plasma membrane
1.16 4.72e-04 GO:0071944 cell periphery

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.62 6.26e-04 GO:0004984 olfactory receptor activity