Motif ID: HBP1_HMGB_SSRP1_UBTF.p2

Z-value: 2.052


Transcription factors associated with HBP1_HMGB_SSRP1_UBTF.p2:

Gene SymbolEntrez IDGene Name
HBP1 26959 HMG-box transcription factor 1
HMGB2 3148 high-mobility group box 2
HMGB3 3149 high-mobility group box 3
SSRP1 6749 structure specific recognition protein 1
UBTF 7343 upstream binding transcription factor, RNA polymerase I

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HMGB3chrX_+_149902415-0.449.0e-02Click!
UBTFchr17_-_396523910.411.2e-01Click!
HMGB2chr4_-_1744920290.263.3e-01Click!
SSRP1chr11_-_56859900-0.126.6e-01Click!
HBP1chr7_+_1065966410.029.4e-01Click!


Activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2.

activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2


Sorted Z-values histogram for motif HBP1_HMGB_SSRP1_UBTF.p2

Sorted Z-values for motif HBP1_HMGB_SSRP1_UBTF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HBP1_HMGB_SSRP1_UBTF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_81544432 6.595 LPHN2
latrophilin 2
chrX_+_135079461 4.380 NM_001167819
FHL1
four and a half LIM domains 1
chr9_+_108665168 4.354 NM_021224
ZNF462
zinc finger protein 462
chr1_+_161305188 4.112 NM_005613
RGS4
regulator of G-protein signaling 4
chr9_-_23816062 3.578 NM_004432
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr1_-_224993498 3.569 NM_002221
ITPKB
inositol 1,4,5-trisphosphate 3-kinase B
chr4_-_186814852 3.342 SORBS2
sorbin and SH3 domain containing 2
chr2_-_207738858 3.290 NM_003709
KLF7
Kruppel-like factor 7 (ubiquitous)
chr11_+_131286513 3.007 NTM
neurotrimin
chr8_-_6407882 2.961 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chr7_-_104696678 2.909 NM_182691
SRPK2
SRSF protein kinase 2
chr7_-_27186400 2.880 NM_153715
HOXA10
homeobox A10
chrX_+_123062143 2.806 STAG2
stromal antigen 2
chr13_-_73605914 2.734 NM_007249
KLF12
Kruppel-like factor 12
chr8_-_72436519 2.535 EYA1
eyes absent homolog 1 (Drosophila)
chr6_-_56824672 2.519 DST
dystonin
chr3_+_174598937 2.386 NM_014932
NLGN1
neuroligin 1
chr2_-_160181206 2.281 NM_013450
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr9_+_126460511 2.251


chr7_-_26202626 2.248 HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr3_-_145049853 2.236 NM_173653
SLC9A9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chrX_+_28515479 2.223 NM_014271
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr5_+_15553736 2.183 FBXL7
F-box and leucine-rich repeat protein 7
chr10_+_104525877 2.183 NM_017787
C10orf26
chromosome 10 open reading frame 26
chr3_-_65999548 2.176 NM_001033057
NM_004742
NM_015520
MAGI1


membrane associated guanylate kinase, WW and PDZ domain containing 1


chr7_-_27149750 2.143 NM_019102
HOXA5
homeobox A5
chr3_-_130373241 2.137 CNBP
CCHC-type zinc finger, nucleic acid binding protein
chr3_+_148593911 2.127


chr13_-_59223074 2.122


chr6_-_134540666 2.110 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr4_+_119174947 2.096 NM_004784
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr8_-_93099040 2.065 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr18_-_22382497 2.039 NM_001142730
KCTD1
potassium channel tetramerisation domain containing 1
chr1_-_177106702 1.998 NM_004673
ANGPTL1
angiopoietin-like 1
chr13_-_98428244 1.997 NM_001130048
NM_001130050
DOCK9

dedicator of cytokinesis 9

chr21_-_27261276 1.993 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr4_-_186815116 1.988 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr11_+_131285747 1.974 NM_001144058
NM_001144059
NM_016522
NTM


neurotrimin


chr7_-_83662152 1.927 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr8_-_29262240 1.926 NM_057158
DUSP4
dual specificity phosphatase 4
chr5_-_111119846 1.914 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr9_+_117955890 1.907 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr2_+_12775814 1.898


chr6_+_12398514 1.887 NM_001168319
NM_001955
EDN1

endothelin 1

chrX_+_77889861 1.872 NM_005296
LPAR4
lysophosphatidic acid receptor 4
chr11_-_85107569 1.871 NM_206929
SYTL2
synaptotagmin-like 2
chr3_+_29297806 1.865 NM_001003792
NM_001003793
NM_001177711
NM_001177712
NM_014483
RBMS3




RNA binding motif, single stranded interacting protein 3




chr19_+_12995782 1.853 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr8_-_108579270 1.829 NM_001146
ANGPT1
angiopoietin 1
chr1_+_66570363 1.780 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chr5_-_88004891 1.775 LOC645323
hypothetical LOC645323
chr6_-_56824371 1.774 DST
dystonin
chr17_-_41625921 1.750 NM_001193466
KIAA1267
KIAA1267
chr9_-_14303509 1.741 NFIB
nuclear factor I/B
chr11_-_85108030 1.711 NM_001162952
NM_206930
SYTL2

synaptotagmin-like 2

chr20_+_31613800 1.708 NM_001039709
NM_005093
CBFA2T2

core-binding factor, runt domain, alpha subunit 2; translocated to, 2

chr5_+_121493113 1.706 NM_207317
ZNF474
zinc finger protein 474
chr3_-_55496370 1.701 NM_003392
WNT5A
wingless-type MMTV integration site family, member 5A
chr3_-_122951200 1.700 NM_004487
GOLGB1
golgin B1
chrX_+_135079120 1.698 NM_001159704
FHL1
four and a half LIM domains 1
chrX_-_33267646 1.669 NM_000109
DMD
dystrophin
chr17_+_71095733 1.656 MYO15B
myosin XVB pseudogene
chrX_-_99778340 1.613 NM_003270
TSPAN6
tetraspanin 6
chr12_-_24606616 1.606 NM_152989
SOX5
SRY (sex determining region Y)-box 5
chr17_+_55854636 1.600 NM_181707
C17orf64
chromosome 17 open reading frame 64
chr15_-_68177244 1.586 TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr4_+_54790190 1.573 PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr7_+_134114912 1.572 CALD1
caldesmon 1
chr21_-_31853160 1.567 NM_003253
TIAM1
T-cell lymphoma invasion and metastasis 1
chr5_-_178977441 1.566 HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr2_+_12775336 1.555 TRIB2
tribbles homolog 2 (Drosophila)
chr4_+_90252990 1.548 NM_145715
TIGD2
tigger transposable element derived 2
chr7_-_122627235 1.519 NM_022444
SLC13A1
solute carrier family 13 (sodium/sulfate symporters), member 1
chr5_+_98132898 1.512 NM_001012761
RGMB
RGM domain family, member B
chr1_+_161305558 1.508 NM_001113381
RGS4
regulator of G-protein signaling 4
chr3_-_55496607 1.502 WNT5A
wingless-type MMTV integration site family, member 5A
chr6_-_128883125 1.501 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr20_+_56369012 1.499


chr7_+_134114957 1.495 CALD1
caldesmon 1
chr1_-_191422346 1.490 NM_003783
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr1_-_68470585 1.486 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr13_-_73606362 1.481 KLF12
Kruppel-like factor 12
chr15_-_68177280 1.478 TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr5_+_140730014 1.474 NM_018924
NM_032097
PCDHGB3

protocadherin gamma subfamily B, 3

chrX_-_142551587 1.454 NM_001184749
SLITRK4
SLIT and NTRK-like family, member 4
chr13_-_52320774 1.449 NM_002590
NM_032949
PCDH8

protocadherin 8

chr5_+_170668892 1.418 NM_021025
TLX3
T-cell leukemia homeobox 3
chr15_-_68177283 1.417 NM_001105192
NM_005078
NM_020908
TLE3


transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)


chr5_-_16989371 1.416 NM_012334
MYO10
myosin X
chr2_-_110665188 1.404 NM_033514
LIMS3-LOC440895
LIMS3
LIMS3-LOC440895 read-through
LIM and senescent cell antigen-like domains 3
chr8_-_93184629 1.395 NM_001198633
NM_175634
RUNX1T1

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

chr1_-_23568854 1.385 NM_001077195
ZNF436
zinc finger protein 436
chr12_-_91063441 1.384 NM_001731
BTG1
B-cell translocation gene 1, anti-proliferative
chr7_+_113853790 1.372 NM_001172767
NM_148899
FOXP2

forkhead box P2

chr3_-_194118321 1.365 MB21D2
Mab-21 domain containing 2
chr11_-_78829342 1.364 NM_001098816
ODZ4
odz, odd Oz/ten-m homolog 4 (Drosophila)
chr15_+_81907176 1.359 SH3GL3
SH3-domain GRB2-like 3
chr15_-_32398220 1.347 NM_005135
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr2_+_33213111 1.337 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr18_+_13601664 1.324 NM_001003674
NM_001003675
C18orf1

chromosome 18 open reading frame 1

chr11_-_85074848 1.312 NM_152723
CCDC89
coiled-coil domain containing 89
chr5_-_71838875 1.312 NM_152625
ZNF366
zinc finger protein 366
chr5_-_83716346 1.310 NM_005711
EDIL3
EGF-like repeats and discoidin I-like domains 3
chr13_-_109757442 1.303 NM_001845
COL4A1
collagen, type IV, alpha 1
chr5_-_39400319 1.301 NM_001737
C9
complement component 9
chr4_-_41579325 1.295


chr18_-_13905534 1.294 NM_000529
MC2R
melanocortin 2 receptor (adrenocorticotropic hormone)
chr5_+_15553768 1.292 FBXL7
F-box and leucine-rich repeat protein 7
chr6_+_21774624 1.277 FLJ22536
hypothetical locus LOC401237
chr1_+_168898898 1.270 PRRX1
paired related homeobox 1
chr1_+_22107137 1.269 RPL21
ribosomal protein L21
chr9_+_27099138 1.258 NM_000459
TEK
TEK tyrosine kinase, endothelial
chr1_+_148306439 1.256 VPS45
vacuolar protein sorting 45 homolog (S. cerevisiae)
chr3_-_69254226 1.246 NM_198271
LMOD3
leiomodin 3 (fetal)
chr22_+_36422940 1.244 NM_001039141
TRIOBP
TRIO and F-actin binding protein
chr13_+_23742846 1.236 SPATA13
spermatogenesis associated 13
chr5_-_146813343 1.229 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr9_+_115678365 1.224 NM_133374
ZNF618
zinc finger protein 618
chr4_+_37655385 1.220 TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr3_+_116824840 1.216 NM_001130064
NM_002045
GAP43

growth associated protein 43

chr1_+_84540921 1.212 NM_001134664
SAMD13
sterile alpha motif domain containing 13
chr4_+_3264509 1.210 RGS12
regulator of G-protein signaling 12
chr5_-_39460687 1.206 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr12_+_13240983 1.201 EMP1
epithelial membrane protein 1
chr8_-_72437020 1.199 NM_000503
EYA1
eyes absent homolog 1 (Drosophila)
chr11_-_69228286 1.197 NM_005117
FGF19
fibroblast growth factor 19
chr6_+_99979490 1.194


chr8_-_72436832 1.187 EYA1
eyes absent homolog 1 (Drosophila)
chr4_-_111777651 1.185 PITX2
paired-like homeodomain 2
chr12_+_14429499 1.182 ATF7IP
activating transcription factor 7 interacting protein
chr1_+_24158898 1.177 PNRC2
proline-rich nuclear receptor coactivator 2
chr7_+_28692122 1.174 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr12_+_13240987 1.167 EMP1
epithelial membrane protein 1
chr7_-_27171673 1.159 NM_152739
HOXA9
homeobox A9
chr5_+_15553539 1.159 FBXL7
F-box and leucine-rich repeat protein 7
chr18_-_21184824 1.149


chr5_+_148766632 1.146 LOC728264
hypothetical LOC728264
chr7_-_27108826 1.145 NM_006735
HOXA2
homeobox A2
chr10_+_80672842 1.143 ZMIZ1
zinc finger, MIZ-type containing 1
chr6_-_134680888 1.142 NM_001143676
SGK1
serum/glucocorticoid regulated kinase 1
chr5_-_83715947 1.134 EDIL3
EGF-like repeats and discoidin I-like domains 3
chr7_+_77005287 1.130 NM_001131008
NM_001131009
PTPN12

protein tyrosine phosphatase, non-receptor type 12

chr12_-_88270375 1.124 NM_001946
NM_022652
DUSP6

dual specificity phosphatase 6

chr3_-_11585264 1.120 NM_001128221
VGLL4
vestigial like 4 (Drosophila)
chr1_+_24158887 1.118 NM_017761
PNRC2
proline-rich nuclear receptor coactivator 2
chr7_-_44854188 1.111 H2AFV
H2A histone family, member V
chr9_-_14303899 1.108 NFIB
nuclear factor I/B
chr3_-_115960807 1.107 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr13_-_35327798 1.099 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr7_-_44854222 1.094 NM_012412
NM_138635
NM_201436
NM_201516
NM_201517
H2AFV




H2A histone family, member V




chr14_+_85066265 1.091 FLRT2
fibronectin leucine rich transmembrane protein 2
chrX_-_138742050 1.086 NM_001010986
NM_173694
ATP11C

ATPase, class VI, type 11C

chr2_+_110013297 1.086 NM_033514
LIMS3-LOC440895
LIMS3
LIMS3-LOC440895 read-through
LIM and senescent cell antigen-like domains 3
chr7_-_11838260 1.086 NM_015204
THSD7A
thrombospondin, type I, domain containing 7A
chr2_-_56266408 1.086 LOC100129434
hypothetical LOC100129434
chr7_-_44854183 1.084 H2AFV
H2A histone family, member V
chr7_-_44854145 1.076 H2AFV
H2A histone family, member V
chr3_-_129023850 1.074 NM_007283
MGLL
monoglyceride lipase
chr8_+_70567634 1.068 SULF1
sulfatase 1
chr5_+_140719773 1.067 NM_018923
NM_032096
PCDHGB2

protocadherin gamma subfamily B, 2

chr8_-_82557956 1.067 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr20_+_11846536 1.067 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr4_-_83569853 1.063 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr3_-_66634031 1.061 LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr12_+_47498778 1.049 NM_000725
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr16_+_31391998 1.048 NM_015927
TGFB1I1
transforming growth factor beta 1 induced transcript 1
chr1_+_196874867 1.047 PTPRC
protein tyrosine phosphatase, receptor type, C
chr1_+_154120170 1.047 SYT11
synaptotagmin XI
chr5_-_114543632 1.044 NM_001017397
NM_001017398
NM_018700
TRIM36


tripartite motif containing 36


chr7_-_47588652 1.043 TNS3
tensin 3
chr2_-_121875610 1.036 CLASP1
cytoplasmic linker associated protein 1
chr5_+_61910318 1.034 NM_181506
LRRC70
leucine rich repeat containing 70
chr15_+_81906983 1.027 NM_003027
SH3GL3
SH3-domain GRB2-like 3
chr4_-_138673078 1.020 NM_019035
PCDH18
protocadherin 18
chr19_+_60858230 1.016 U2AF2
U2 small nuclear RNA auxiliary factor 2
chr22_+_36928972 1.015 NM_001161573
MAFF
v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr9_-_97308687 1.011 PTCH1
patched 1
chr10_+_119292699 1.011


chr5_-_39461054 1.006 NM_001343
DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr11_+_129496792 1.006 APLP2
amyloid beta (A4) precursor-like protein 2
chr8_+_70567581 1.005 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr4_-_176970372 1.000 GPM6A
glycoprotein M6A
chr4_+_39874921 0.994 NM_004310
RHOH
ras homolog gene family, member H
chr9_-_14304036 0.989 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr7_-_44854092 0.988 H2AFV
H2A histone family, member V
chr2_+_108637698 0.987 NM_001193485
LIMS1
LIM and senescent cell antigen-like domains 1
chr2_+_36777336 0.986 NM_001177969
NM_001177970
NM_001177971
NM_001177972
NM_053276
VIT




vitrin




chr4_+_24923490 0.985 NM_024936
ZCCHC4
zinc finger, CCHC domain containing 4
chr12_-_16649211 0.981 LMO3
LIM domain only 3 (rhombotin-like 2)
chr4_+_78297418 0.979 CCNG2
cyclin G2
chr9_-_72673753 0.977 NM_001007470
NM_020952
NM_024971
NM_206944
NM_206945
NM_206946
NM_206947
NM_206948
TRPM3







transient receptor potential cation channel, subfamily M, member 3







chr4_+_183302105 0.975 ODZ3
odz, odd Oz/ten-m homolog 3 (Drosophila)
chr9_-_16717887 0.973 BNC2
basonuclin 2
chr17_-_41626032 0.972 NM_015443
KIAA1267
KIAA1267
chr11_+_19328846 0.964 NM_001111018
NAV2
neuron navigator 2
chr7_+_18501876 0.955 NM_014707
NM_178423
HDAC9

histone deacetylase 9

chr3_+_180348818 0.955 NM_006218
PIK3CA
phosphoinositide-3-kinase, catalytic, alpha polypeptide
chr7_-_47588266 0.954 TNS3
tensin 3
chr9_-_71476917 0.950 NM_001163
APBA1
amyloid beta (A4) precursor protein-binding, family A, member 1
chr3_-_48576204 0.950 NM_033199
UCN2
urocortin 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.42 2.71e-22 GO:0032502 developmental process
1.44 6.90e-21 GO:0007275 multicellular organismal development
1.44 5.75e-19 GO:0048856 anatomical structure development
1.47 7.29e-19 GO:0048731 system development
1.31 4.48e-18 GO:0032501 multicellular organismal process
1.52 2.70e-15 GO:0030154 cell differentiation
1.51 3.75e-15 GO:0048869 cellular developmental process
1.60 7.19e-14 GO:0009653 anatomical structure morphogenesis
1.56 6.91e-12 GO:0007399 nervous system development
1.20 3.82e-11 GO:0050794 regulation of cellular process
1.41 8.37e-10 GO:0048523 negative regulation of cellular process
1.39 1.93e-09 GO:0048519 negative regulation of biological process
1.43 3.93e-09 GO:0048513 organ development
1.17 5.23e-09 GO:0050789 regulation of biological process
1.16 2.06e-08 GO:0065007 biological regulation
1.61 7.38e-08 GO:0048468 cell development
1.59 3.29e-07 GO:0022008 neurogenesis
2.04 3.75e-07 GO:0001501 skeletal system development
1.26 4.88e-07 GO:0023052 signaling
1.60 5.69e-07 GO:0048699 generation of neurons
1.67 6.91e-07 GO:0009790 embryo development
1.27 9.06e-07 GO:0007165 signal transduction
1.31 9.62e-07 GO:0048518 positive regulation of biological process
1.33 1.00e-06 GO:0048522 positive regulation of cellular process
1.63 1.30e-06 GO:2000026 regulation of multicellular organismal development
1.66 1.50e-06 GO:0030182 neuron differentiation
1.71 2.42e-06 GO:0009887 organ morphogenesis
3.07 2.67e-06 GO:0048706 embryonic skeletal system development
1.66 9.12e-06 GO:0032989 cellular component morphogenesis
1.87 9.15e-06 GO:0009792 embryo development ending in birth or egg hatching
1.87 1.11e-05 GO:0043009 chordate embryonic development
2.92 1.22e-05 GO:0051271 negative regulation of cellular component movement
1.67 1.44e-05 GO:0000902 cell morphogenesis
1.17 1.54e-05 GO:0050896 response to stimulus
1.64 1.72e-05 GO:0007167 enzyme linked receptor protein signaling pathway
2.95 2.53e-05 GO:0030336 negative regulation of cell migration
2.95 2.53e-05 GO:2000146 negative regulation of cell motility
1.64 2.85e-05 GO:0045893 positive regulation of transcription, DNA-dependent
1.50 3.27e-05 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.67 3.33e-05 GO:0048666 neuron development
1.53 5.37e-05 GO:0040011 locomotion
1.70 7.64e-05 GO:0000904 cell morphogenesis involved in differentiation
1.50 1.02e-04 GO:0050793 regulation of developmental process
1.74 1.10e-04 GO:0048812 neuron projection morphogenesis
1.75 1.25e-04 GO:0007409 axonogenesis
2.69 1.30e-04 GO:0040013 negative regulation of locomotion
2.02 1.43e-04 GO:0003002 regionalization
1.69 1.61e-04 GO:0031175 neuron projection development
2.24 1.64e-04 GO:0009952 anterior/posterior pattern formation
1.55 1.70e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
1.73 1.73e-04 GO:0023057 negative regulation of signaling
1.73 1.85e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.58 1.96e-04 GO:0010628 positive regulation of gene expression
1.67 2.41e-04 GO:0048585 negative regulation of response to stimulus
1.57 2.92e-04 GO:0045595 regulation of cell differentiation
1.69 3.09e-04 GO:0072358 cardiovascular system development
1.69 3.09e-04 GO:0072359 circulatory system development
1.81 3.27e-04 GO:0007389 pattern specification process
1.68 3.48e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.70 3.90e-04 GO:0010648 negative regulation of cell communication
1.65 4.62e-04 GO:0048858 cell projection morphogenesis
1.72 5.90e-04 GO:0009968 negative regulation of signal transduction
1.22 6.61e-04 GO:0016043 cellular component organization
1.81 7.14e-04 GO:0051093 negative regulation of developmental process
1.64 7.24e-04 GO:0032990 cell part morphogenesis
1.86 8.32e-04 GO:0051270 regulation of cellular component movement
1.87 9.08e-04 GO:0061061 muscle structure development
1.19 9.10e-04 GO:0051716 cellular response to stimulus
1.74 1.06e-03 GO:0048598 embryonic morphogenesis
1.54 1.07e-03 GO:0051254 positive regulation of RNA metabolic process
1.50 1.51e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.88 1.70e-03 GO:0030334 regulation of cell migration
1.08 1.92e-03 GO:0009987 cellular process
1.49 1.95e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.26 2.05e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.68 2.41e-03 GO:0016477 cell migration
2.38 2.51e-03 GO:0048736 appendage development
2.38 2.51e-03 GO:0060173 limb development
1.21 2.56e-03 GO:0071840 cellular component organization or biogenesis
1.54 2.59e-03 GO:0030030 cell projection organization
1.86 2.68e-03 GO:0045596 negative regulation of cell differentiation
1.86 2.68e-03 GO:2000145 regulation of cell motility
2.40 2.89e-03 GO:0035107 appendage morphogenesis
2.40 2.89e-03 GO:0035108 limb morphogenesis
1.99 3.33e-03 GO:0007517 muscle organ development
2.23 3.43e-03 GO:0048705 skeletal system morphogenesis
1.45 3.96e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.45 4.22e-03 GO:0009891 positive regulation of biosynthetic process
1.59 4.68e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.33 6.81e-03 GO:0009966 regulation of signal transduction
1.78 7.20e-03 GO:0040012 regulation of locomotion
1.44 7.26e-03 GO:0009888 tissue development
1.72 7.82e-03 GO:0007411 axon guidance
1.62 8.25e-03 GO:0051094 positive regulation of developmental process
1.37 8.75e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.24 8.85e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.41 9.48e-03 GO:0042127 regulation of cell proliferation
1.80 1.04e-02 GO:0001568 blood vessel development
1.25 1.05e-02 GO:0051252 regulation of RNA metabolic process
1.46 1.13e-02 GO:0007155 cell adhesion
1.46 1.13e-02 GO:0022610 biological adhesion
1.30 1.17e-02 GO:0023051 regulation of signaling
1.25 1.25e-02 GO:0006355 regulation of transcription, DNA-dependent
1.75 1.49e-02 GO:0001944 vasculature development
1.50 1.53e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.23 1.67e-02 GO:0010468 regulation of gene expression
1.58 1.75e-02 GO:0048646 anatomical structure formation involved in morphogenesis
1.53 1.91e-02 GO:0006928 cellular component movement
1.73 2.21e-02 GO:0030029 actin filament-based process
1.53 2.23e-02 GO:0045892 negative regulation of transcription, DNA-dependent
1.27 2.36e-02 GO:0007166 cell surface receptor linked signaling pathway
1.57 2.57e-02 GO:0048870 cell motility
1.57 2.57e-02 GO:0051674 localization of cell
1.19 2.71e-02 GO:0060255 regulation of macromolecule metabolic process
1.40 2.97e-02 GO:0006351 transcription, DNA-dependent
1.22 3.13e-02 GO:0071842 cellular component organization at cellular level
1.18 3.19e-02 GO:0080090 regulation of primary metabolic process
2.31 4.33e-02 GO:0030326 embryonic limb morphogenesis
2.31 4.33e-02 GO:0035113 embryonic appendage morphogenesis
2.14 4.46e-02 GO:0006469 negative regulation of protein kinase activity
1.18 4.50e-02 GO:0031323 regulation of cellular metabolic process
2.66 4.80e-02 GO:0048704 embryonic skeletal system morphogenesis
1.46 4.94e-02 GO:0010558 negative regulation of macromolecule biosynthetic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.66 1.14e-06 GO:0030054 cell junction
1.76 4.17e-04 GO:0005578 proteinaceous extracellular matrix
2.53 5.18e-04 GO:0030027 lamellipodium
2.27 7.87e-04 GO:0044420 extracellular matrix part
1.14 1.63e-03 GO:0005634 nucleus
1.61 2.37e-03 GO:0045202 synapse
2.02 3.08e-03 GO:0005912 adherens junction
1.61 5.82e-03 GO:0031012 extracellular matrix
2.17 6.08e-03 GO:0030055 cell-substrate junction
2.22 6.92e-03 GO:0005925 focal adhesion
1.15 7.95e-03 GO:0071944 cell periphery
1.15 1.23e-02 GO:0005886 plasma membrane
1.87 1.87e-02 GO:0070161 anchoring junction
2.12 1.97e-02 GO:0005924 cell-substrate adherens junction
1.40 2.15e-02 GO:0044451 nucleoplasm part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.59 2.98e-09 GO:0001071 nucleic acid binding transcription factor activity
1.59 2.98e-09 GO:0003700 sequence-specific DNA binding transcription factor activity
1.68 7.09e-08 GO:0043565 sequence-specific DNA binding
1.15 9.93e-07 GO:0005515 protein binding
1.50 1.60e-06 GO:0030528 transcription regulator activity
1.68 6.34e-06 GO:0008092 cytoskeletal protein binding
1.84 3.64e-05 GO:0003779 actin binding
4.59 6.96e-03 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity
4.59 6.96e-03 GO:0019198 transmembrane receptor protein phosphatase activity
1.22 1.47e-02 GO:0003677 DNA binding
1.06 1.98e-02 GO:0005488 binding
7.34 4.05e-02 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity