Motif ID: HES1.p2

Z-value: 1.665


Transcription factors associated with HES1.p2:

Gene SymbolEntrez IDGene Name
HES1 3280 hairy and enhancer of split 1, (Drosophila)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HES1chr3_+_1953366310.068.2e-01Click!


Activity profile for motif HES1.p2.

activity profile for motif HES1.p2


Sorted Z-values histogram for motif HES1.p2

Sorted Z-values for motif HES1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HES1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_225615556 2.599 NM_014689
DOCK10
dedicator of cytokinesis 10
chr12_+_120840829 2.116 NM_001178003
NM_144668
WDR66

WD repeat domain 66

chr7_+_129918408 1.700 NM_177525
MEST
mesoderm specific transcript homolog (mouse)
chr17_-_53920699 1.668 NM_001080439
HSF5
heat shock transcription factor family member 5
chr22_-_45037882 1.555 NM_006071
PKDREJ
polycystic kidney disease (polycystin) and REJ homolog (sperm receptor for egg jelly homolog, sea urchin)
chr7_+_154720547 1.361 INSIG1
insulin induced gene 1
chr13_-_76358433 1.315 NM_138444
KCTD12
potassium channel tetramerisation domain containing 12
chr13_+_20175481 1.231 NM_138284
IL17D
interleukin 17D
chr7_+_154720416 1.202 NM_005542
NM_198336
NM_198337
INSIG1


insulin induced gene 1


chr13_-_76358370 1.188 KCTD12
potassium channel tetramerisation domain containing 12
chr8_-_93184629 1.133 NM_001198633
NM_175634
RUNX1T1

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

chr9_-_139316523 1.099 NM_001004354
NRARP
NOTCH-regulated ankyrin repeat protein
chr11_+_43920385 1.097 NM_001145033
C11orf96
chromosome 11 open reading frame 96
chr1_+_199108705 0.982 NM_005298
GPR25
G protein-coupled receptor 25
chr16_+_66153810 0.970 NM_001191022
NM_006565
CTCF

CCCTC-binding factor (zinc finger protein)

chr20_-_4752067 0.962 NM_014737
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr17_-_10042579 0.956 NM_201433
GAS7
growth arrest-specific 7
chr17_+_75689985 0.951 GAA
glucosidase, alpha; acid
chr11_+_46325457 0.922 NM_003646
DGKZ
diacylglycerol kinase, zeta
chr18_+_2836979 0.915 NM_032048
EMILIN2
elastin microfibril interfacer 2
chr19_-_1352474 0.889 NM_000156
NM_138924
GAMT

guanidinoacetate N-methyltransferase

chr16_+_65754788 0.886 NM_001040667
NM_001538
HSF4

heat shock transcription factor 4

chr2_+_149895274 0.865 NM_194317
LYPD6
LY6/PLAUR domain containing 6
chr7_+_98084531 0.857 NM_002523
NPTX2
neuronal pentraxin II
chr3_-_185025989 0.835 NM_024871
MAP6D1
MAP6 domain containing 1
chr16_-_87535106 0.832 NM_175931
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr18_-_490583 0.804 NM_130386
COLEC12
collectin sub-family member 12
chr13_-_77390907 0.799 NM_001122659
NM_003991
EDNRB

endothelin receptor type B

chr1_+_164063684 0.777 UCK2
uridine-cytidine kinase 2
chr17_+_75689955 0.772 GAA
glucosidase, alpha; acid
chr1_+_226937732 0.766 RHOU
ras homolog gene family, member U
chr7_+_24579239 0.757 NM_016447
MPP6
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr1_-_9111674 0.727 NM_024980
GPR157
G protein-coupled receptor 157
chr9_+_6747636 0.726 NM_001146694
NM_001146695
NM_015061
KDM4C


lysine (K)-specific demethylase 4C


chr6_+_137185441 0.726 PEX7
peroxisomal biogenesis factor 7
chr1_-_94147537 0.723 GCLM
glutamate-cysteine ligase, modifier subunit
chr7_-_100068612 0.710 TFR2
transferrin receptor 2
chr2_-_175255717 0.707 NM_001077269
WIPF1
WAS/WASL interacting protein family, member 1
chr4_+_39734902 0.704 NM_018177
N4BP2
NEDD4 binding protein 2
chr1_-_94147574 0.696 NM_002061
GCLM
glutamate-cysteine ligase, modifier subunit
chr22_-_49311439 0.668 NM_001169110
SCO2
SCO cytochrome oxidase deficient homolog 2 (yeast)
chr17_+_75689894 0.665 NM_000152
NM_001079803
NM_001079804
GAA


glucosidase, alpha; acid


chr14_-_80757327 0.662 NM_201595
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr16_+_2465109 0.662 NM_020705
TBC1D24
TBC1 domain family, member 24
chr7_+_129919134 0.658 MEST
mesoderm specific transcript homolog (mouse)
chr20_+_56701224 0.653 NM_024663
NPEPL1
aminopeptidase-like 1
chr9_+_91115924 0.647 NM_001827
CKS2
CDC28 protein kinase regulatory subunit 2
chr13_-_27967215 0.646 NM_001159920
NM_001160030
NM_001160031
NM_002019
FLT1



fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)



chr19_+_7651741 0.628 NM_174894
NM_001042461
TRAPPC5

trafficking protein particle complex 5

chr2_-_135193011 0.625 NM_030923
TMEM163
transmembrane protein 163
chr17_-_45562112 0.623 NM_174920
SAMD14
sterile alpha motif domain containing 14
chr9_+_36126667 0.617 GLIPR2
GLI pathogenesis-related 2
chr16_+_30617962 0.610 NM_006662
SRCAP
Snf2-related CREBBP activator protein
chr5_-_142763393 0.604 NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr7_-_87687276 0.603 SRI
sorcin
chr19_-_1603325 0.601 NM_003200
TCF3
transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
chr9_+_36126710 0.600 NM_022343
GLIPR2
GLI pathogenesis-related 2
chr7_-_44854092 0.594 H2AFV
H2A histone family, member V
chr12_+_8741746 0.588 NM_020734
RIMKLB
ribosomal modification protein rimK-like family member B
chr12_+_48046946 0.588 NM_023071
SPATS2
spermatogenesis associated, serine-rich 2
chr4_-_110574363 0.584 1/2-SBSRNA4
lncRNA_BC009800
chr1_-_94147616 0.580 GCLM
glutamate-cysteine ligase, modifier subunit
chr6_-_43305156 0.575 NM_006443
NM_199184
C6orf108

chromosome 6 open reading frame 108

chr7_-_87687302 0.571 NM_003130
SRI
sorcin
chr3_+_154035425 0.568 NM_002563
P2RY1
purinergic receptor P2Y, G-protein coupled, 1
chr17_-_1478859 0.566 NM_152346
SLC43A2
solute carrier family 43, member 2
chr12_+_6893751 0.564 NM_001975
ENO2
enolase 2 (gamma, neuronal)
chr2_-_218865451 0.564 NM_022152
TMBIM1
transmembrane BAX inhibitor motif containing 1
chr7_-_44854183 0.561 H2AFV
H2A histone family, member V
chr18_-_44731078 0.561 NM_001190821
NM_005904
SMAD7

SMAD family member 7

chr1_-_32574185 0.555 NM_023009
MARCKSL1
MARCKS-like 1
chr2_-_38457934 0.554 NM_001135673
NM_022374
ATL2

atlastin GTPase 2

chr14_-_80757018 0.554 NM_015859
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr4_-_83938920 0.553 NM_001037582
NM_024906
SCD5

stearoyl-CoA desaturase 5

chr15_+_97462675 0.551 NM_015286
NM_145728
SYNM

synemin, intermediate filament protein

chr17_+_45940911 0.547 MYCBPAP
MYCBP associated protein
chr4_-_39655944 0.544 NM_001100399
NM_001100400
PDS5A

PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)

chr7_-_15692551 0.542 MEOX2
mesenchyme homeobox 2
chr17_-_7968121 0.542 NM_001165967
NM_032580
HES7

hairy and enhancer of split 7 (Drosophila)

chr3_+_198214173 0.539 LOC100507057
MFI2
hypothetical LOC100507057
antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
chr21_-_45786709 0.533 NM_194255
SLC19A1
solute carrier family 19 (folate transporter), member 1
chr5_+_110587546 0.531 NM_001744
CAMK4
calcium/calmodulin-dependent protein kinase IV
chr2_+_207016525 0.526 NM_003812
ADAM23
ADAM metallopeptidase domain 23
chr7_+_148590152 0.518 NM_001195220
ZNF783
zinc finger family member 783
chr4_+_110574274 0.508 SEC24B
SEC24 family, member B (S. cerevisiae)
chr13_+_78068246 0.508 LOC780529
hypothetical LOC780529
chr14_-_88953059 0.507 NM_005197
FOXN3
forkhead box N3
chr22_-_27405708 0.503 NM_001145418
TTC28
tetratricopeptide repeat domain 28
chr17_-_4640335 0.499 LOC284014
hypothetical protein LOC284014
chr17_+_45940743 0.495 NM_032133
MYCBPAP
MYCBP associated protein
chr15_+_97009194 0.494 IGF1R
insulin-like growth factor 1 receptor
chr12_-_98902562 0.494 NM_152788
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr5_+_14196287 0.493 NM_007118
TRIO
triple functional domain (PTPRF interacting)
chr4_-_83570318 0.488 NM_031372
HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr2_-_73350103 0.486 NM_001080410
FBXO41
F-box protein 41
chrX_+_151991474 0.480 NM_001170944
NM_032882
LOC100287428
PNMA6A
paraneoplastic antigen-like protein 6A related gene
paraneoplastic antigen like 6A
chr3_+_106568334 0.479 NM_001627
ALCAM
activated leukocyte cell adhesion molecule
chr9_+_6747919 0.478 KDM4C
lysine (K)-specific demethylase 4C
chr2_+_108702338 0.477 NM_006267
RANBP2
RAN binding protein 2
chr11_-_86060812 0.475 NM_001014811
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr2_+_10009242 0.471 NM_198182
GRHL1
grainyhead-like 1 (Drosophila)
chr19_+_7801110 0.469 NM_145245
EVI5L
ecotropic viral integration site 5-like
chr19_-_10474266 0.466 NM_012289
KEAP1
kelch-like ECH-associated protein 1
chr17_-_59131210 0.464 NM_030576
LIMD2
LIM domain containing 2
chr1_-_6684484 0.462 NM_018198
DNAJC11
DnaJ (Hsp40) homolog, subfamily C, member 11
chr11_+_19691397 0.459 NM_145117
NM_182964
NAV2

neuron navigator 2

chr17_-_26175764 0.457 CRLF3
cytokine receptor-like factor 3
chr6_+_111515341 0.455 SLC16A10
solute carrier family 16, member 10 (aromatic amino acid transporter)
chr1_+_156229934 0.455 KIRREL
kin of IRRE like (Drosophila)
chr6_-_74286876 0.454 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr22_+_18091065 0.454 NM_000407
GP1BB
glycoprotein Ib (platelet), beta polypeptide
chr10_-_15250616 0.453 NM_004808
NMT2
N-myristoyltransferase 2
chr19_+_62787319 0.450 NM_001010879
ZIK1
zinc finger protein interacting with K protein 1 homolog (mouse)
chr7_-_45927263 0.449 NM_000598
NM_001013398
IGFBP3

insulin-like growth factor binding protein 3

chr1_+_22909916 0.447 NM_004442
NM_017449
EPHB2

EPH receptor B2

chr7_-_5536704 0.445 NM_001101
ACTB
actin, beta
chr19_+_54309423 0.442 NM_022165
LIN7B
lin-7 homolog B (C. elegans)
chr2_-_222145240 0.442 NM_004438
EPHA4
EPH receptor A4
chr11_-_1549719 0.441 NM_004420
DUSP8
dual specificity phosphatase 8
chr16_-_4341266 0.435 NM_016069
PAM16
presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr4_+_689529 0.435 NM_006315
PCGF3
polycomb group ring finger 3
chr13_+_42046182 0.433 NM_003701
TNFSF11
tumor necrosis factor (ligand) superfamily, member 11
chr11_+_131285747 0.433 NM_001144058
NM_001144059
NM_016522
NTM


neurotrimin


chr5_-_138758783 0.432 NM_001161546
LOC389333
hypothetical protein LOC389333
chr4_+_25930405 0.432 NM_005349
NM_203283
RBPJ

recombination signal binding protein for immunoglobulin kappa J region

chr22_+_34107051 0.430 NM_002133
HMOX1
heme oxygenase (decycling) 1
chr6_+_86216457 0.429 NT5E
5'-nucleotidase, ecto (CD73)
chr18_+_2896178 0.429 EMILIN2
elastin microfibril interfacer 2
chr2_+_5750229 0.427 NM_003108
SOX11
SRY (sex determining region Y)-box 11
chr5_-_142763481 0.426 NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr13_+_40929679 0.425 C13orf15
chromosome 13 open reading frame 15
chr6_+_133604181 0.423 NM_004100
NM_172103
NM_172105
EYA4


eyes absent homolog 4 (Drosophila)


chr10_+_129595289 0.423 NM_006504
PTPRE
protein tyrosine phosphatase, receptor type, E
chr2_-_85969527 0.418 NM_003896
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr12_-_3732478 0.417 EFCAB4B
EF-hand calcium binding domain 4B
chr11_-_86061003 0.416 NM_006680
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr5_-_74098641 0.414 NM_032380
NM_170681
NM_170691
GFM2


G elongation factor, mitochondrial 2


chr3_+_51403760 0.409 NM_013286
RBM15B
RNA binding motif protein 15B
chr13_+_40929525 0.408 NM_014059
C13orf15
chromosome 13 open reading frame 15
chr3_+_49034050 0.406 NM_199069
NM_199070
NDUFAF3

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3

chr14_+_57932396 0.405 NM_207377
TOMM20L
translocase of outer mitochondrial membrane 20 homolog (yeast)-like
chr4_-_7991992 0.405 NM_001134647
NM_198595
AFAP1

actin filament associated protein 1

chr3_-_185218311 0.404 NM_001023587
NM_005688
ABCC5

ATP-binding cassette, sub-family C (CFTR/MRP), member 5

chr19_+_54309443 0.401 LIN7B
lin-7 homolog B (C. elegans)
chr11_+_124438407 0.399 SLC37A2
solute carrier family 37 (glycerol-3-phosphate transporter), member 2
chr1_+_164063276 0.399 NM_012474
UCK2
uridine-cytidine kinase 2
chr16_-_2330594 0.399 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr21_+_44033821 0.398 NM_003683
RRP1
ribosomal RNA processing 1 homolog (S. cerevisiae)
chr5_-_142763418 0.398 NM_000176
NM_001020825
NM_001024094
NR3C1


nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)


chr3_-_191321367 0.397 LEPREL1
leprecan-like 1
chr15_+_83160914 0.397 NM_020778
ALPK3
alpha-kinase 3
chr8_+_1936549 0.397 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr9_-_112381593 0.397 NM_153366
SVEP1
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr12_+_92295738 0.395 NM_019094
NM_199040
NUDT4

NUDT4P1
nudix (nucleoside diphosphate linked moiety X)-type motif 4

nudix (nucleoside diphosphate linked moiety X)-type motif 4 pseudogene 1
chr1_-_43196911 0.395 SLC2A1
solute carrier family 2 (facilitated glucose transporter), member 1
chr10_+_101282679 0.395 NM_145285
NKX2-3
NK2 transcription factor related, locus 3 (Drosophila)
chr21_-_18113514 0.395 NM_001100420
NM_001100421
NM_017447
C21orf91


chromosome 21 open reading frame 91


chr4_+_91267706 0.392 NM_001145065
FAM190A
family with sequence similarity 190, member A
chr5_-_43075904 0.392 NM_001014279
C5orf39
chromosome 5 open reading frame 39
chr5_+_131657964 0.389 NM_003059
SLC22A4
solute carrier family 22 (organic cation/ergothioneine transporter), member 4
chr3_-_109292444 0.387 NM_001777
NM_198793
CD47

CD47 molecule

chr22_-_49311722 0.387 NM_001169109
SCO2
SCO cytochrome oxidase deficient homolog 2 (yeast)
chr11_-_65304397 0.385 NM_138368
DKFZp761E198
DKFZp761E198 protein
chr10_+_129595349 0.383 PTPRE
protein tyrosine phosphatase, receptor type, E
chr11_+_46256161 0.382 CREB3L1
cAMP responsive element binding protein 3-like 1
chr2_-_198358253 0.381 NM_033030
BOLL
bol, boule-like (Drosophila)
chr11_-_69228286 0.381 NM_005117
FGF19
fibroblast growth factor 19
chr16_+_65840275 0.380 NM_004594
SLC9A5
solute carrier family 9 (sodium/hydrogen exchanger), member 5
chr16_-_2330712 0.380 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr8_+_1937711 0.378 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr19_+_44524972 0.378 SAMD4B
sterile alpha motif domain containing 4B
chr14_-_63264445 0.377 NM_030791
SGPP1
sphingosine-1-phosphate phosphatase 1
chr19_+_7651706 0.377 NM_001042462
TRAPPC5
trafficking protein particle complex 5
chr13_+_48692472 0.377 NM_001507
MLNR
motilin receptor
chr5_+_77692094 0.376 NM_004866
SCAMP1
secretory carrier membrane protein 1
chr20_+_36810510 0.374 NM_024855
ACTR5
ARP5 actin-related protein 5 homolog (yeast)
chr11_+_66643311 0.374 NM_012308
KDM2A
lysine (K)-specific demethylase 2A
chr5_-_1547872 0.374 LPCAT1
lysophosphatidylcholine acyltransferase 1
chr10_-_119124727 0.373 NM_173791
PDZD8
PDZ domain containing 8
chr14_-_92651896 0.373 NM_001142593
NM_001142594
NM_014216
ITPK1


inositol 1,3,4-triphosphate 5/6 kinase


chr17_+_7393098 0.372 NM_172089
NM_003809
TNFSF12-TNFSF13
TNFSF12
TNFSF12-TNFSF13 readthrough
tumor necrosis factor (ligand) superfamily, member 12
chr3_-_129024665 0.371 NM_001003794
MGLL
monoglyceride lipase
chr1_-_6684465 0.369 DNAJC11
DnaJ (Hsp40) homolog, subfamily C, member 11
chr19_+_3310138 0.369 NM_205843
NFIC
nuclear factor I/C (CCAAT-binding transcription factor)
chr1_+_178466064 0.369 NM_033343
LHX4
LIM homeobox 4
chr16_-_2330738 0.366 NM_001089
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr12_+_2939250 0.366 TEAD4
TEA domain family member 4
chr17_-_19711580 0.366 NM_001142610
NM_014683
ULK2

unc-51-like kinase 2 (C. elegans)

chr18_-_11138760 0.366 NM_022068
FAM38B
family with sequence similarity 38, member B
chr11_-_113251415 0.366 NM_020886
USP28
ubiquitin specific peptidase 28
chr10_-_103589586 0.365 NM_173194
KCNIP2
Kv channel interacting protein 2
chr19_+_44524936 0.365 SAMD4B
sterile alpha motif domain containing 4B
chr12_-_37585602 0.365 NM_153634
CPNE8
copine VIII
chr4_+_110574376 0.365 NM_001042734
NM_006323
SEC24B

SEC24 family, member B (S. cerevisiae)

chr8_-_29262240 0.363 NM_057158
DUSP4
dual specificity phosphatase 4
chr17_-_76985538 0.363


chr17_+_1120607 0.363 NM_001164405
BHLHA9
basic helix-loop-helix family, member a9
chr14_+_70178126 0.362 NM_015351
TTC9
tetratricopeptide repeat domain 9
chr13_-_19997914 0.361 NM_015974
CRYL1
crystallin, lambda 1
chr1_-_6684426 0.361 DNAJC11
DnaJ (Hsp40) homolog, subfamily C, member 11

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.22 2.97e-14 GO:0044237 cellular metabolic process
1.28 1.02e-13 GO:0044260 cellular macromolecule metabolic process
1.11 2.12e-13 GO:0009987 cellular process
1.18 2.47e-11 GO:0008152 metabolic process
1.19 2.82e-11 GO:0044238 primary metabolic process
1.22 7.24e-10 GO:0043170 macromolecule metabolic process
1.39 8.36e-09 GO:0006464 protein modification process
1.38 1.51e-08 GO:0043412 macromolecule modification
1.31 7.13e-08 GO:0044267 cellular protein metabolic process
1.15 8.46e-08 GO:0050794 regulation of cellular process
1.15 1.77e-07 GO:0050789 regulation of biological process
1.13 1.19e-06 GO:0065007 biological regulation
1.25 1.44e-06 GO:0006807 nitrogen compound metabolic process
1.49 1.84e-06 GO:0006793 phosphorus metabolic process
1.49 1.84e-06 GO:0006796 phosphate metabolic process
1.29 2.42e-06 GO:0044249 cellular biosynthetic process
1.28 3.57e-06 GO:0009058 biosynthetic process
1.24 7.39e-06 GO:0034641 cellular nitrogen compound metabolic process
1.59 1.02e-05 GO:0007167 enzyme linked receptor protein signaling pathway
1.26 1.41e-05 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.24 4.05e-05 GO:0019538 protein metabolic process
1.21 1.77e-04 GO:0016043 cellular component organization
1.27 1.92e-04 GO:0048523 negative regulation of cellular process
1.34 3.13e-04 GO:0007399 nervous system development
1.20 3.13e-04 GO:0071840 cellular component organization or biogenesis
1.43 5.55e-04 GO:0050793 regulation of developmental process
1.31 5.98e-04 GO:0034645 cellular macromolecule biosynthetic process
1.25 6.88e-04 GO:0048519 negative regulation of biological process
1.24 6.92e-04 GO:0048522 positive regulation of cellular process
1.30 1.14e-03 GO:0023051 regulation of signaling
1.29 1.33e-03 GO:0009059 macromolecule biosynthetic process
1.22 1.44e-03 GO:0048518 positive regulation of biological process
2.08 1.53e-03 GO:0016311 dephosphorylation
1.25 1.60e-03 GO:0090304 nucleic acid metabolic process
1.32 1.64e-03 GO:0009966 regulation of signal transduction
1.55 2.52e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.78 2.75e-03 GO:0030334 regulation of cell migration
1.45 2.84e-03 GO:0006468 protein phosphorylation
1.21 3.12e-03 GO:0048731 system development
1.18 3.20e-03 GO:0032502 developmental process
1.40 3.25e-03 GO:0022008 neurogenesis
1.47 3.28e-03 GO:0045595 regulation of cell differentiation
1.41 3.62e-03 GO:0048699 generation of neurons
1.76 4.47e-03 GO:2000145 regulation of cell motility
1.22 4.59e-03 GO:0071842 cellular component organization at cellular level
1.72 4.65e-03 GO:0051270 regulation of cellular component movement
1.19 4.91e-03 GO:0048856 anatomical structure development
1.38 5.26e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.21 5.89e-03 GO:0071841 cellular component organization or biogenesis at cellular level
1.40 7.04e-03 GO:0016310 phosphorylation
1.18 7.67e-03 GO:0007275 multicellular organismal development
1.26 9.15e-03 GO:0010467 gene expression
2.39 9.88e-03 GO:0030336 negative regulation of cell migration
2.39 9.88e-03 GO:2000146 negative regulation of cell motility
1.80 1.17e-02 GO:0048514 blood vessel morphogenesis
1.17 1.26e-02 GO:0031323 regulation of cellular metabolic process
1.17 1.47e-02 GO:0080090 regulation of primary metabolic process
1.28 1.62e-02 GO:0009653 anatomical structure morphogenesis
1.26 1.62e-02 GO:0016070 RNA metabolic process
1.16 1.65e-02 GO:0019222 regulation of metabolic process
2.29 1.79e-02 GO:0051271 negative regulation of cellular component movement
2.00 2.75e-02 GO:0006470 protein dephosphorylation
1.17 2.91e-02 GO:0060255 regulation of macromolecule metabolic process
1.66 3.25e-02 GO:0040012 regulation of locomotion
1.30 3.66e-02 GO:0051641 cellular localization
1.54 3.71e-02 GO:0040008 regulation of growth

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.15 1.06e-26 GO:0044424 intracellular part
1.14 1.36e-25 GO:0005622 intracellular
1.17 4.12e-18 GO:0043231 intracellular membrane-bounded organelle
1.17 7.22e-18 GO:0043227 membrane-bounded organelle
1.18 1.54e-17 GO:0005737 cytoplasm
1.15 4.16e-17 GO:0043226 organelle
1.15 5.13e-17 GO:0043229 intracellular organelle
1.20 3.31e-11 GO:0005634 nucleus
1.17 4.74e-09 GO:0044444 cytoplasmic part
1.28 3.39e-06 GO:0031974 membrane-enclosed lumen
1.26 2.53e-05 GO:0043233 organelle lumen
1.29 3.49e-05 GO:0031981 nuclear lumen
1.27 3.55e-05 GO:0005829 cytosol
1.26 4.41e-05 GO:0070013 intracellular organelle lumen
1.26 5.62e-05 GO:0044428 nuclear part
1.04 8.96e-05 GO:0044464 cell part
1.04 9.41e-05 GO:0005623 cell
1.13 4.29e-04 GO:0044446 intracellular organelle part
1.12 1.67e-03 GO:0044422 organelle part
1.27 1.72e-02 GO:0005654 nucleoplasm
1.44 1.86e-02 GO:0005730 nucleolus
1.17 3.79e-02 GO:0043228 non-membrane-bounded organelle
1.17 3.79e-02 GO:0043232 intracellular non-membrane-bounded organelle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.10 8.22e-14 GO:0005488 binding
1.16 1.60e-10 GO:0005515 protein binding
1.15 1.76e-05 GO:0003824 catalytic activity
1.30 4.23e-05 GO:0016740 transferase activity
1.24 1.93e-04 GO:0000166 nucleotide binding
1.19 5.87e-04 GO:0003676 nucleic acid binding
1.76 1.28e-03 GO:0016791 phosphatase activity
1.38 1.31e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.42 1.36e-03 GO:0019899 enzyme binding
1.96 1.42e-03 GO:0004721 phosphoprotein phosphatase activity
1.63 2.00e-03 GO:0042578 phosphoric ester hydrolase activity
1.16 2.23e-03 GO:0043167 ion binding
1.16 2.63e-03 GO:0046872 metal ion binding
1.16 3.18e-03 GO:0043169 cation binding
2.23 4.39e-03 GO:0017016 Ras GTPase binding
1.39 9.51e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.20 1.19e-02 GO:0003677 DNA binding
1.32 1.56e-02 GO:0030528 transcription regulator activity
2.07 1.86e-02 GO:0031267 small GTPase binding
1.99 2.29e-02 GO:0051020 GTPase binding
1.19 2.31e-02 GO:0046914 transition metal ion binding
1.41 2.48e-02 GO:0004672 protein kinase activity
1.35 2.83e-02 GO:0016301 kinase activity
1.47 2.85e-02 GO:0016874 ligase activity
1.21 3.33e-02 GO:0008270 zinc ion binding