Motif ID: HNF1A.p2

Z-value: 2.878


Transcription factors associated with HNF1A.p2:

Gene SymbolEntrez IDGene Name
HNF1A 6927 HNF1 homeobox A

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HNF1Achr12_+_1199009310.611.2e-02Click!


Activity profile for motif HNF1A.p2.

activity profile for motif HNF1A.p2


Sorted Z-values histogram for motif HNF1A.p2

Sorted Z-values for motif HNF1A.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HNF1A.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_40995564 10.367 PRODH2
proline dehydrogenase (oxidase) 2
chr19_-_40995606 8.443 PRODH2
proline dehydrogenase (oxidase) 2
chr16_-_86527608 6.610 NM_001739
CA5A
carbonic anhydrase VA, mitochondrial
chr7_-_44547382 5.595 NM_001101648
NM_013389
NPC1L1

NPC1 (Niemann-Pick disease, type C1, gene)-like 1

chr6_-_52060327 5.520 NM_138694
NM_170724
PKHD1

polycystic kidney and hepatic disease 1 (autosomal recessive)

chr2_-_88208650 4.713 NM_001443
FABP1
fatty acid binding protein 1, liver
chr6_-_24491498 4.696 NM_001195610
DCDC2
doublecortin domain containing 2
chr4_-_69852090 4.559 NM_024743
UGT2A3
UDP glucuronosyltransferase 2 family, polypeptide A3
chr17_+_71065478 4.547 LLGL2
lethal giant larvae homolog 2 (Drosophila)
chr21_-_46399900 4.545 NM_006657
NM_206965
FTCD

formiminotransferase cyclodeaminase

chr6_+_31731667 4.455 APOM
apolipoprotein M
chr3_-_162572441 4.441 NM_001040100
C3orf57
chromosome 3 open reading frame 57
chr17_+_71154240 4.376 NM_001162997
LOC100130933
hypothetical protein LOC100130933
chr6_+_31731647 4.312 NM_019101
APOM
apolipoprotein M
chr4_-_69116839 4.144 NM_001077
UGT2B17
UDP glucuronosyltransferase 2 family, polypeptide B17
chr14_+_38772870 4.073 NM_054024
MIA2
melanoma inhibitory activity 2
chr4_-_977163 4.006 NM_022042
NM_134425
NM_213613
SLC26A1


solute carrier family 26 (sulfate transporter), member 1


chr1_+_48460943 3.958 NM_001011547
NM_001135181
SLC5A9

solute carrier family 5 (sodium/glucose cotransporter), member 9

chr20_+_42417752 3.780 NM_001030003
NM_001030004
NM_175914
HNF4A


hepatocyte nuclear factor 4, alpha


chr2_+_27573206 3.684 NM_001486
GCKR
glucokinase (hexokinase 4) regulator
chr11_-_117200618 3.605 NM_001127489
NM_001680
FXYD2

FXYD domain containing ion transport regulator 2

chr16_-_46826588 3.536 NM_032583
NM_145186
ABCC11

ATP-binding cassette, sub-family C (CFTR/MRP), member 11

chr10_+_99334411 3.499 HOGA1
4-hydroxy-2-oxoglutarate aldolase 1
chr8_+_21967008 3.432 NM_001114137
EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr5_+_175908948 3.418 NM_017675
CDHR2
cadherin-related family member 2
chr1_+_17779528 3.345 NM_001011722
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr2_+_234302511 3.221 NM_019093
UGT1A3
UDP glucuronosyltransferase 1 family, polypeptide A3
chr17_+_4638966 3.208 NM_001014985
GLTPD2
glycolipid transfer protein domain containing 2
chr5_+_140509803 3.188 NM_018939
PCDHB6
protocadherin beta 6
chr16_+_21152516 3.152 NM_145865
ANKS4B
ankyrin repeat and sterile alpha motif domain containing 4B
chr6_-_116488458 3.101 NM_002031
FRK
fyn-related kinase
chr7_-_50600536 3.042 NM_001082971
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr15_+_56511466 2.997 NM_000236
LIPC
lipase, hepatic
chr20_+_42463419 2.984 HNF4A
hepatocyte nuclear factor 4, alpha
chr20_+_42417502 2.955 HNF4A
hepatocyte nuclear factor 4, alpha
chr16_-_67943157 2.811 NM_144676
TMED6
transmembrane emp24 protein transport domain containing 6
chr20_+_42463387 2.709 HNF4A
hepatocyte nuclear factor 4, alpha
chr10_+_44726635 2.705 NM_001123376
TMEM72
transmembrane protein 72
chr7_-_47545717 2.670 NM_022748
TNS3
tensin 3
chr17_-_202557 2.650 RPH3AL
rabphilin 3A-like (without C2 domains)
chr20_-_7869068 2.642 NM_017545
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr20_+_42463350 2.632 HNF4A
hepatocyte nuclear factor 4, alpha
chr7_+_45894480 2.616 NM_000596
IGFBP1
insulin-like growth factor binding protein 1
chr4_-_69570919 2.587 NM_001076
UGT2B15
UDP glucuronosyltransferase 2 family, polypeptide B15
chr20_+_41621079 2.563 NM_170693
SGK2
serum/glucocorticoid regulated kinase 2
chr19_-_44135166 2.455 NM_148169
FBXO17
F-box protein 17
chr14_-_93924663 2.441 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr14_-_93859394 2.428 NM_001756
SERPINA6
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr20_+_41621119 2.415 SGK2
serum/glucocorticoid regulated kinase 2
chr15_-_88150823 2.381 ANPEP
alanyl (membrane) aminopeptidase
chr16_+_88224175 2.330 DPEP1
dipeptidase 1 (renal)
chr16_+_88224276 2.256 DPEP1
dipeptidase 1 (renal)
chr14_-_93829113 2.225 NM_016186
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr14_+_20226762 2.194 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr20_+_42463279 2.131 NM_000457
NM_178849
NM_178850
HNF4A


hepatocyte nuclear factor 4, alpha


chr2_+_101981888 2.092 NM_173343
IL1R2
interleukin 1 receptor, type II
chr6_-_29563657 2.078 NM_052967
MAS1L
MAS1 oncogene-like
chr14_-_93829309 2.042 SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr16_-_65510230 1.983 NM_004062
CDH16
cadherin 16, KSP-cadherin
chr7_-_104354325 1.956 LOC723809
hypothetical LOC723809
chr17_-_202617 1.879 NM_001190411
NM_001190412
NM_001190413
NM_006987
RPH3AL



rabphilin 3A-like (without C2 domains)



chr14_-_93829347 1.859 NM_001100607
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr12_+_54910767 1.834 NM_001135195
SLC39A5
solute carrier family 39 (metal ion transporter), member 5
chr2_-_168812132 1.833 NM_013233
STK39
serine threonine kinase 39
chrX_-_131375217 1.831 NM_001170701
NM_001170702
NM_001170703
MBNL3


muscleblind-like 3 (Drosophila)


chr4_-_186970366 1.828 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr1_+_18680010 1.782 NM_152375
KLHDC7A
kelch domain containing 7A
chr17_+_1586034 1.767 WDR81
WD repeat domain 81
chr11_-_62539857 1.761 NM_001184732
NM_001184733
NM_001184736
NM_004254
SLC22A8



solute carrier family 22 (organic anion transporter), member 8



chr2_+_62787534 1.754 NM_001142614
EHBP1
EH domain binding protein 1
chr14_+_94097513 1.734 NM_006215
SERPINA4
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
chr1_-_204455269 1.726 NM_001007544
C1orf186
chromosome 1 open reading frame 186
chr17_+_38306339 1.725 NM_000151
G6PC
glucose-6-phosphatase, catalytic subunit
chr2_-_63518589 1.692 NM_001042692
WDPCP
WD repeat containing planar cell polarity effector
chr6_-_33655811 1.666 BAK1
BCL2-antagonist/killer 1
chr1_-_20014180 1.633 NM_019062
RNF186
ring finger protein 186
chr11_+_46697312 1.584 NM_000506
F2
coagulation factor II (thrombin)
chr11_+_46697345 1.575 F2
coagulation factor II (thrombin)
chr11_+_46697335 1.568 F2
coagulation factor II (thrombin)
chr12_-_15757114 1.508 EPS8
epidermal growth factor receptor pathway substrate 8
chr8_-_87311624 1.501 NM_138817
SLC7A13
solute carrier family 7, (cationic amino acid transporter, y+ system) member 13
chr14_-_93924873 1.477 NM_000295
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr17_-_61655915 1.437 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr6_+_167624792 1.437 NM_001143947
NM_018974
UNC93A

unc-93 homolog A (C. elegans)

chr19_-_53081383 1.414 NM_003167
SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr6_-_33655995 1.402 NM_001188
BAK1
BCL2-antagonist/killer 1
chr4_+_154345039 1.383 NM_015271
TRIM2
tripartite motif containing 2
chr6_-_133161318 1.379 NM_052831
C6orf192
chromosome 6 open reading frame 192
chr8_-_17797127 1.373 NM_147203
NM_201553
NM_004467
NM_201552
FGL1



fibrinogen-like 1



chr2_+_151922350 1.333 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr19_-_53081326 1.333 SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr22_-_36836620 1.329 NM_025045
BAIAP2L2
BAI1-associated protein 2-like 2
chr22_-_36836478 1.325 BAIAP2L2
BAI1-associated protein 2-like 2
chr20_+_9236446 1.318 NM_000933
PLCB4
phospholipase C, beta 4
chr14_+_21203136 1.317 NM_001001912
OR4E2
olfactory receptor, family 4, subfamily E, member 2
chr6_+_167456230 1.278 NM_031409
CCR6
chemokine (C-C motif) receptor 6
chr17_+_77910411 1.276 NM_207459
TEX19
testis expressed 19
chr6_+_64289585 1.267 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr6_-_52736231 1.260 NM_000846
GSTA2
glutathione S-transferase alpha 2
chr8_-_124818754 1.237 NM_001003954
NM_004306
ANXA13

annexin A13

chr16_-_20271530 1.224 NM_001008389
NM_003361
UMOD

uromodulin

chr7_+_139175420 1.216 NM_001061
NM_001166253
NM_030984
TBXAS1


thromboxane A synthase 1 (platelet)


chr13_-_99983945 1.184 NM_033110
A2LD1
AIG2-like domain 1
chr11_-_121492010 1.183 NM_001001786
BLID
BH3-like motif containing, cell death inducer
chr12_-_122400937 1.168 NM_001167856
NM_018183
SBNO1

strawberry notch homolog 1 (Drosophila)

chr4_+_3413489 1.158 NM_001528
HGFAC
HGF activator
chr3_+_185430910 1.125 NM_138345
VWA5B2
von Willebrand factor A domain containing 5B2
chr2_-_207291364 1.090 NM_001093730
DYTN
dystrotelin
chr19_-_47790820 1.082 NM_001816
CEACAM8
carcinoembryonic antigen-related cell adhesion molecule 8
chr10_+_101532450 1.077 NM_000392
ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr8_-_101802911 1.071 PABPC1
poly(A) binding protein, cytoplasmic 1
chr2_+_234245243 1.065 NM_021027
UGT1A9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr19_+_750281 1.043 PTBP1
polypyrimidine tract binding protein 1
chr1_-_42402973 1.035 NM_033553
GUCA2A
guanylate cyclase activator 2A (guanylin)
chr2_+_234266250 1.032 NM_001072
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr10_+_114144512 1.029 ACSL5
acyl-CoA synthetase long-chain family member 5
chr2_+_101874809 1.024 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr3_-_171070314 1.012 NM_024727
LRRC31
leucine rich repeat containing 31
chr20_+_31713750 1.010 NM_080825
C20orf144
chromosome 20 open reading frame 144
chr6_-_26038817 1.007 NM_005835
SLC17A2
solute carrier family 17 (sodium phosphate), member 2
chr1_+_42391678 0.993 NM_007102
GUCA2B
guanylate cyclase activator 2B (uroguanylin)
chr8_+_76482661 0.992 HNF4G
hepatocyte nuclear factor 4, gamma
chr4_+_155703581 0.990 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chr19_-_63556632 0.987 NM_130786
A1BG
alpha-1-B glycoprotein
chr4_+_74566325 0.987 NM_001133
AFM
afamin
chr2_+_234292162 0.986 NM_007120
UGT1A4
UDP glucuronosyltransferase 1 family, polypeptide A4
chr17_+_65009986 0.951 MAP2K6
mitogen-activated protein kinase kinase 6
chr3_+_63928459 0.932 NM_001128149
ATXN7
ataxin 7
chr4_+_3413457 0.932 HGFAC
HGF activator
chr2_+_101874765 0.918 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr6_-_31007905 0.914 NM_205854
SFTA2
surfactant associated 2
chr20_-_17589122 0.908 RRBP1
ribosome binding protein 1 homolog 180kDa (dog)
chr10_-_69736600 0.905 PBLD
phenazine biosynthesis-like protein domain containing
chr3_-_57209319 0.896 NM_003865
HESX1
HESX homeobox 1
chr2_+_28892366 0.883 NM_001008779
SPDYA
speedy homolog A (Xenopus laevis)
chr13_-_32658215 0.869 NM_178007
STARD13
StAR-related lipid transfer (START) domain containing 13
chr12_+_21175394 0.858 NM_006446
SLCO1B1
solute carrier organic anion transporter family, member 1B1
chr9_+_80134302 0.857 PSAT1
phosphoserine aminotransferase 1
chr15_+_60726801 0.854 NM_015059
TLN2
talin 2
chr19_-_40996040 0.827 NM_021232
PRODH2
proline dehydrogenase (oxidase) 2
chr10_+_101532544 0.827 ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr6_-_137536412 0.799 NM_052962
NM_181309
NM_181310
IL22RA2


interleukin 22 receptor, alpha 2


chr2_+_234286376 0.797 NM_019078
UGT1A5
UDP glucuronosyltransferase 1 family, polypeptide A5
chr3_-_166278969 0.788 NM_001041
SI
sucrase-isomaltase (alpha-glucosidase)
chr20_+_35406497 0.780 NM_005417
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr2_-_101370355 0.774 NM_153836
CREG2
cellular repressor of E1A-stimulated genes 2
chrX_-_105169370 0.767 NM_000354
SERPINA7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr5_-_147191334 0.757 SPINK1
serine peptidase inhibitor, Kazal type 1
chr21_-_18697829 0.755 NM_002772
TMPRSS15
transmembrane protease, serine 15
chr11_+_26310253 0.740 NM_031418
ANO3
anoctamin 3
chr11_+_64114857 0.738 NM_144585
NM_153378
SLC22A12

solute carrier family 22 (organic anion/urate transporter), member 12

chr14_+_87560646 0.736 LOC283587
hypothetical protein LOC283587
chr16_-_56389176 0.733 NM_001130099
KIFC3
kinesin family member C3
chr3_+_187866464 0.727 NM_000412
HRG
histidine-rich glycoprotein
chr20_-_43972061 0.725 PLTP
phospholipid transfer protein
chr4_-_100359353 0.712 NM_000672
NM_001102470
ADH6

alcohol dehydrogenase 6 (class V)

chr1_-_228916559 0.691 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr1_-_151852128 0.689 NM_080388
S100A16
S100 calcium binding protein A16
chrX_+_117410693 0.684 WDR44
WD repeat domain 44
chr16_-_21344158 0.670 NM_130464
NPIPL3
nuclear pore complex interacting protein-like 3
chr16_+_56286212 0.653 NM_032269
CCDC135
coiled-coil domain containing 135
chr2_-_87102453 0.646 NM_002665
NM_001032392
PLGLB2
PLGLB1
plasminogen-like B2
plasminogen-like B1
chr3_-_168674502 0.634 NM_006217
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr20_+_61841553 0.625 NM_020062
SLC2A4RG
SLC2A4 regulator
chr17_+_1592879 0.613 NM_000934
NM_001165921
SERPINF2

serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2

chr9_+_130257254 0.609 NM_153436
ODF2
outer dense fiber of sperm tails 2
chr2_-_227952249 0.607 NM_024795
TM4SF20
transmembrane 4 L six family member 20
chr7_-_158304062 0.606 ESYT2
extended synaptotagmin-like protein 2
chrX_+_70351812 0.600 GJB1
gap junction protein, beta 1, 32kDa
chr5_-_160044844 0.598 ATP10B
ATPase, class V, type 10B
chr22_+_43476755 0.598 NM_181334
PRR5-ARHGAP8
PRR5
PRR5-ARHGAP8 readthrough
proline rich 5 (renal)
chr16_+_30118036 0.594 NM_001017390
NM_177552
SULT1A4
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr6_-_31789824 0.579


chr20_-_4938913 0.576 NM_203327
SLC23A2
solute carrier family 23 (nucleobase transporters), member 2
chr6_+_155453114 0.571 NM_012454
TIAM2
T-cell lymphoma invasion and metastasis 2
chr4_-_40211324 0.570 RBM47
RNA binding motif protein 47
chr21_-_42219849 0.570 NM_199050
C2CD2
C2 calcium-dependent domain containing 2
chr3_+_150675117 0.569 NM_004617
TM4SF4
transmembrane 4 L six family member 4
chr10_-_121592020 0.567 MCMBP
minichromosome maintenance complex binding protein
chr10_-_32707549 0.567 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr16_+_22432344 0.549 NM_001135865
LOC100132247
NPIPL3
nuclear pore complex interacting protein related gene
nuclear pore complex interacting protein-like 3
chr2_+_28572441 0.544 NM_001170585
NM_153021
PLB1

phospholipase B1

chr17_+_1592893 0.540 SERPINF2
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr5_-_147191428 0.537 NM_003122
SPINK1
serine peptidase inhibitor, Kazal type 1
chr7_-_87694218 0.535 NM_198901
SRI
sorcin
chr11_+_61794205 0.534 NM_002411
SCGB2A2
secretoglobin, family 2A, member 2
chr6_+_25862905 0.533 NM_005495
SLC17A4
solute carrier family 17 (sodium phosphate), member 4
chr7_+_129913271 0.527 NM_177524
MEST
mesoderm specific transcript homolog (mouse)
chr22_+_21027538 0.519


chr9_-_115901157 0.516 NM_138424
KIF12
kinesin family member 12
chr12_-_18134319 0.515 NM_024730
RERGL
RERG/RAS-like
chr10_+_99334069 0.514 NM_001134670
NM_138413
HOGA1

4-hydroxy-2-oxoglutarate aldolase 1

chr2_+_182558795 0.514 NM_001080545
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr20_+_56848127 0.501 GNAS
GNAS complex locus
chr5_+_140552087 0.491 NM_018930
PCDHB10
protocadherin beta 10
chr18_+_27425727 0.489 NM_000371
TTR
transthyretin
chr1_+_209586328 0.488 NM_145759
TRAF5
TNF receptor-associated factor 5
chr2_+_208932813 0.473 PTH2R
parathyroid hormone 2 receptor
chr9_-_27287106 0.472 NM_001161585
NM_020641
C9orf11

chromosome 9 open reading frame 11

chr17_-_53335748 0.469 NM_017949
CUEDC1
CUE domain containing 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
8.08 1.72e-10 GO:0006805 xenobiotic metabolic process
8.08 1.72e-10 GO:0071466 cellular response to xenobiotic stimulus
8.02 2.00e-10 GO:0009410 response to xenobiotic stimulus
4.88 2.84e-06 GO:0008202 steroid metabolic process
3.64 5.12e-06 GO:0071702 organic substance transport
2.92 6.62e-06 GO:0006082 organic acid metabolic process
2.76 6.81e-05 GO:0042180 cellular ketone metabolic process
2.74 1.27e-04 GO:0019752 carboxylic acid metabolic process
2.74 1.27e-04 GO:0043436 oxoacid metabolic process
1.83 1.96e-04 GO:0042221 response to chemical stimulus
8.38 3.31e-04 GO:0010951 negative regulation of endopeptidase activity
28.41 4.11e-04 GO:0009812 flavonoid metabolic process
3.61 5.47e-04 GO:0032787 monocarboxylic acid metabolic process
2.34 6.05e-04 GO:0006629 lipid metabolic process
23.24 1.46e-03 GO:0009698 phenylpropanoid metabolic process
4.42 4.59e-03 GO:0015849 organic acid transport
4.56 7.36e-03 GO:0006869 lipid transport
51.13 9.32e-03 GO:0034392 negative regulation of smooth muscle cell apoptosis
1.72 1.08e-02 GO:0065008 regulation of biological quality
15.98 1.27e-02 GO:0015721 bile acid and bile salt transport
8.95 1.37e-02 GO:0030301 cholesterol transport
5.56 1.55e-02 GO:0010466 negative regulation of peptidase activity
8.73 1.63e-02 GO:0006721 terpenoid metabolic process
8.73 1.63e-02 GO:0015918 sterol transport
10.96 1.75e-02 GO:0030195 negative regulation of blood coagulation
4.18 1.86e-02 GO:0010876 lipid localization
4.16 1.99e-02 GO:0046942 carboxylic acid transport
10.58 2.17e-02 GO:0050819 negative regulation of coagulation
6.82 2.59e-02 GO:0033500 carbohydrate homeostasis
6.82 2.59e-02 GO:0042593 glucose homeostasis
13.46 3.23e-02 GO:0034381 plasma lipoprotein particle clearance
6.60 3.31e-02 GO:0015718 monocarboxylic acid transport
20.45 3.45e-02 GO:0019934 cGMP-mediated signaling
3.84 4.56e-02 GO:0052548 regulation of endopeptidase activity
6.30 4.69e-02 GO:0019748 secondary metabolic process
7.46 4.74e-02 GO:0061041 regulation of wound healing
9.30 4.74e-02 GO:0001523 retinoid metabolic process
9.30 4.74e-02 GO:0016101 diterpenoid metabolic process
4.43 4.98e-02 GO:0051346 negative regulation of hydrolase activity

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
5.48 1.02e-06 GO:0016324 apical plasma membrane
4.85 1.21e-06 GO:0045177 apical part of cell
2.60 8.76e-06 GO:0005624 membrane fraction
2.52 2.04e-05 GO:0005626 insoluble fraction
2.26 3.18e-05 GO:0000267 cell fraction
3.90 1.84e-04 GO:0005792 microsome
3.77 2.98e-04 GO:0042598 vesicular fraction
2.31 5.08e-03 GO:0005789 endoplasmic reticulum membrane
1.67 5.32e-03 GO:0005576 extracellular region
2.26 7.72e-03 GO:0042175 nuclear membrane-endoplasmic reticulum network
6.89 1.25e-02 GO:0031983 vesicle lumen
2.11 1.49e-02 GO:0005615 extracellular space
1.60 1.55e-02 GO:0044459 plasma membrane part
2.13 1.66e-02 GO:0044432 endoplasmic reticulum part
1.89 2.26e-02 GO:0005783 endoplasmic reticulum
6.17 2.54e-02 GO:0031091 platelet alpha granule
6.82 4.44e-02 GO:0005903 brush border
1.37 4.94e-02 GO:0005886 plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
21.91 1.73e-11 GO:0015020 glucuronosyltransferase activity
3.73 1.41e-04 GO:0004857 enzyme inhibitor activity
5.64 1.56e-04 GO:0008194 UDP-glycosyltransferase activity
7.94 5.08e-04 GO:0033293 monocarboxylic acid binding
5.81 2.46e-03 GO:0004867 serine-type endopeptidase inhibitor activity
2.98 4.30e-03 GO:0022804 active transmembrane transporter activity
4.18 9.56e-03 GO:0004866 endopeptidase inhibitor activity
3.84 1.08e-02 GO:0016758 transferase activity, transferring hexosyl groups
4.07 1.25e-02 GO:0031406 carboxylic acid binding
18.59 1.27e-02 GO:0001972 retinoic acid binding
4.01 1.42e-02 GO:0061135 endopeptidase regulator activity
3.96 1.61e-02 GO:0030414 peptidase inhibitor activity
7.87 3.00e-02 GO:0005504 fatty acid binding
1.95 4.74e-02 GO:0030234 enzyme regulator activity
13.64 4.92e-02 GO:0008514 organic anion transmembrane transporter activity