Motif ID: MTF1.p2

Z-value: 3.760


Transcription factors associated with MTF1.p2:

Gene SymbolEntrez IDGene Name
MTF1 4520 metal-regulatory transcription factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MTF1chr1_-_380978110.058.5e-01Click!


Activity profile for motif MTF1.p2.

activity profile for motif MTF1.p2


Sorted Z-values histogram for motif MTF1.p2

Sorted Z-values for motif MTF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MTF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_-_87535106 5.136 NM_175931
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr8_-_143805371 4.215 LOC100288181
hypothetical LOC100288181
chr22_-_30072217 3.857 NM_014323
NM_032050
NM_032051
NM_032052
PATZ1



POZ (BTB) and AT hook containing zinc finger 1



chr15_+_77511912 3.403 NM_015206
KIAA1024
KIAA1024
chr22_-_30072329 3.308 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr10_-_128884411 3.028 NM_001039762
FAM196A
family with sequence similarity 196, member A
chr12_-_56418295 2.984 NM_001122772
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr3_+_191714533 2.898 NM_001167928
NM_001167929
NM_001167930
NM_001167931
NM_002182
NM_134470
IL1RAP





interleukin 1 receptor accessory protein





chr21_+_41461924 2.794 BACE2
beta-site APP-cleaving enzyme 2
chr9_+_90339835 2.773 NM_001161625
NM_145283
NXNL2

nucleoredoxin-like 2

chr22_-_30071761 2.731 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr13_+_97593469 2.387 FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr13_+_97593411 2.363 NM_001001715
NM_005766
FARP1

FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)

chr7_-_27136876 2.360 NM_002141
HOXA4
homeobox A4
chr13_-_100125103 2.358 NM_001079669
NM_032813
TMTC4

transmembrane and tetratricopeptide repeat containing 4

chr3_+_160964574 2.355 SCHIP1
schwannomin interacting protein 1
chr2_+_207016525 2.335 NM_003812
ADAM23
ADAM metallopeptidase domain 23
chr3_-_127677451 2.294 NM_001040653
NM_025112
ZXDC

ZXD family zinc finger C

chr8_-_82186832 2.253 NM_018440
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr13_-_25523164 2.233 NM_001007538
SHISA2
shisa homolog 2 (Xenopus laevis)
chr1_+_218930542 2.215 C1orf115
chromosome 1 open reading frame 115
chr10_+_129595349 2.145 PTPRE
protein tyrosine phosphatase, receptor type, E
chr8_+_32525269 2.142 NM_001160002
NM_001160004
NM_001160005
NM_001160007
NM_001160008
NM_004495
NM_013956
NM_013957
NM_013958
NM_013960
NM_013964
NRG1










neuregulin 1










chr11_-_63292688 2.124 NM_001144936
C11orf95
chromosome 11 open reading frame 95
chr11_+_17697685 2.089 NM_002478
MYOD1
myogenic differentiation 1
chr13_-_27967215 2.065 NM_001159920
NM_001160030
NM_001160031
NM_002019
FLT1



fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)



chr3_-_185025989 2.064 NM_024871
MAP6D1
MAP6 domain containing 1
chr15_-_76890626 2.062 NM_014272
ADAMTS7
ADAM metallopeptidase with thrombospondin type 1 motif, 7
chr12_+_56406296 2.040 LOC100130776
hypothetical LOC100130776
chr4_+_187302988 2.017 NM_015398
FAM149A
family with sequence similarity 149, member A
chr1_-_226661089 2.015 NM_145214
TRIM11
tripartite motif containing 11
chr8_+_143805595 1.999 NM_016647
C8orf55
chromosome 8 open reading frame 55
chr1_+_226937732 1.981 RHOU
ras homolog gene family, member U
chr22_-_30071565 1.971 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr1_+_33494745 1.946 NM_152493
ZNF362
zinc finger protein 362
chr8_-_145881968 1.928 ARHGAP39
Rho GTPase activating protein 39
chr4_+_42094612 1.928 NM_001080505
SHISA3
shisa homolog 3 (Xenopus laevis)
chr1_+_226937424 1.907 NM_021205
RHOU
ras homolog gene family, member U
chr1_+_208472817 1.906 NM_019605
SERTAD4
SERTA domain containing 4
chrX_-_151996613 1.886 NM_032882
PNMA6A
paraneoplastic antigen like 6A
chr11_+_110675175 1.842 NM_001136105
C11orf93
chromosome 11 open reading frame 93
chr21_+_41461597 1.822 NM_012105
NM_138991
NM_138992
BACE2


beta-site APP-cleaving enzyme 2


chr11_+_46325457 1.822 NM_003646
DGKZ
diacylglycerol kinase, zeta
chr9_-_93751900 1.821 NM_004560
ROR2
receptor tyrosine kinase-like orphan receptor 2
chr16_+_19087035 1.787 NM_016524
SYT17
synaptotagmin XVII
chr13_-_76358433 1.779 NM_138444
KCTD12
potassium channel tetramerisation domain containing 12
chr7_+_89678935 1.758 NM_152999
NM_001040665
STEAP2

six transmembrane epithelial antigen of the prostate 2

chr2_-_39040981 1.751 LOC375196
hypothetical LOC375196
chr13_-_76358370 1.746 KCTD12
potassium channel tetramerisation domain containing 12
chr12_+_130878870 1.717 NM_016155
MMP17
matrix metallopeptidase 17 (membrane-inserted)
chr14_+_95575319 1.703 C14orf132
chromosome 14 open reading frame 132
chr4_-_186629841 1.702 NM_001145411
NM_152775
CCDC110

coiled-coil domain containing 110

chr6_+_142664490 1.680 NM_001032394
NM_001032395
NM_020455
NM_198569
GPR126



G protein-coupled receptor 126



chr2_+_202607554 1.680 NM_003507
FZD7
frizzled homolog 7 (Drosophila)
chr10_-_33663984 1.651 NRP1
neuropilin 1
chr17_+_17525497 1.634 NM_030665
RAI1
retinoic acid induced 1
chr17_+_17525571 1.634


chr15_-_99276933 1.628


chr10_-_92607397 1.625 HTR7
5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)
chr3_-_135575925 1.625 NM_016201
AMOTL2
angiomotin like 2
chr10_+_71232281 1.624 COL13A1
collagen, type XIII, alpha 1
chr5_-_146869811 1.618 NM_001197294
DPYSL3
dihydropyrimidinase-like 3
chr1_-_3437834 1.618 MEGF6
multiple EGF-like-domains 6
chr15_+_99276982 1.612 NM_024652
LRRK1
leucine-rich repeat kinase 1
chr20_+_6696744 1.607 NM_001200
BMP2
bone morphogenetic protein 2
chr13_-_100125028 1.604 TMTC4
transmembrane and tetratricopeptide repeat containing 4
chr10_+_23768203 1.590 NM_001145373
OTUD1
OTU domain containing 1
chr15_+_66658626 1.584 NM_006091
CORO2B
coronin, actin binding protein, 2B
chr16_-_55016872 1.573 NM_001144
AMFR
autocrine motility factor receptor
chr5_-_138758783 1.552 NM_001161546
LOC389333
hypothetical protein LOC389333
chr11_+_35596310 1.544 NM_014344
FJX1
four jointed box 1 (Drosophila)
chr10_-_92607650 1.539 NM_000872
NM_019859
NM_019860
HTR7


5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)


chrX_+_118486390 1.534 NM_001152
SLC25A5
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr7_+_3307445 1.533 NM_152744
SDK1
sidekick homolog 1, cell adhesion molecule (chicken)
chr1_-_1274618 1.522 DVL1
dishevelled, dsh homolog 1 (Drosophila)
chr6_+_159510416 1.513 NM_032532
FNDC1
fibronectin type III domain containing 1
chr3_-_127677400 1.509 ZXDC
ZXD family zinc finger C
chr18_-_44731078 1.504 NM_001190821
NM_005904
SMAD7

SMAD family member 7

chr12_-_122201237 1.502 PITPNM2
phosphatidylinositol transfer protein, membrane-associated 2
chr22_-_49310827 1.501 NM_001169111
NM_005138
SCO2

SCO cytochrome oxidase deficient homolog 2 (yeast)

chr9_+_99785405 1.494 ANP32B
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr2_+_120820140 1.492 NM_002193
INHBB
inhibin, beta B
chr5_-_146869613 1.490 DPYSL3
dihydropyrimidinase-like 3
chr11_-_788196 1.485 NM_001191061
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr9_-_94936319 1.469 NM_004148
NINJ1
ninjurin 1
chr5_+_65927895 1.467 NM_001164664
NM_198828
MAST4

microtubule associated serine/threonine kinase family member 4

chr14_+_102128844 1.465 NM_015156
RCOR1
REST corepressor 1
chr7_-_27206249 1.461 NM_000522
HOXA13
homeobox A13
chr14_+_105028614 1.454 NM_001134875
NM_001134876
C14orf80

chromosome 14 open reading frame 80

chr2_+_238060602 1.451 NM_001042467
NM_024101
MLPH

melanophilin

chr22_+_47350781 1.447 NM_015381
FAM19A5
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr10_+_119292699 1.431


chrX_+_118486419 1.429 SLC25A5
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr13_-_105985313 1.429 NM_004093
EFNB2
ephrin-B2
chr9_-_139437534 1.427 NM_017820
EXD3
exonuclease 3'-5' domain containing 3
chr11_+_76455574 1.419 NM_004055
CAPN5
calpain 5
chr6_+_72653369 1.413 NM_014989
RIMS1
regulating synaptic membrane exocytosis 1
chr9_-_133605037 1.412 RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr9_+_90796169 1.409 NM_005226
S1PR3
sphingosine-1-phosphate receptor 3
chr9_+_99785465 1.381 ANP32B
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr19_+_58733144 1.376 NM_001079906
ZNF331
zinc finger protein 331
chr20_-_4752067 1.369 NM_014737
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr6_+_89912464 1.365 NM_001010853
PM20D2
peptidase M20 domain containing 2
chr16_+_82559600 1.365 NM_019065
NECAB2
N-terminal EF-hand calcium binding protein 2
chr2_-_204108151 1.364 NM_203365
NM_213589
RAPH1

Ras association (RalGDS/AF-6) and pleckstrin homology domains 1

chr7_+_55999559 1.357 NM_001483
GBAS
glioblastoma amplified sequence
chr7_+_150442652 1.356 AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr19_-_5291700 1.354 NM_002850
NM_130853
NM_130854
NM_130855
PTPRS



protein tyrosine phosphatase, receptor type, S



chr2_-_207739815 1.352 KLF7
Kruppel-like factor 7 (ubiquitous)
chr7_-_42243142 1.348 NM_000168
GLI3
GLI family zinc finger 3
chr17_+_45008473 1.347 NXPH3
neurexophilin 3
chr6_-_40663089 1.346 NM_020737
LRFN2
leucine rich repeat and fibronectin type III domain containing 2
chr16_+_55230078 1.344 NM_005946
MT1A
metallothionein 1A
chr3_+_61522219 1.342 NM_002841
PTPRG
protein tyrosine phosphatase, receptor type, G
chr21_-_43671355 1.334 NM_173354
SIK1
salt-inducible kinase 1
chr20_+_34206070 1.329 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr2_-_110230642 1.322 MALL
mal, T-cell differentiation protein-like
chr15_+_89300973 1.315 RCCD1
RCC1 domain containing 1
chr9_+_99785277 1.314 NM_006401
ANP32B
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr2_+_25118417 1.307 NM_014971
EFR3B
EFR3 homolog B (S. cerevisiae)
chr8_-_121893468 1.303 NM_021021
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr6_+_17389752 1.302 NM_001143942
RBM24
RNA binding motif protein 24
chr14_+_101097440 1.288 NM_001362
DIO3
deiodinase, iodothyronine, type III
chr17_-_72093739 1.287 NM_006456
ST6GALNAC2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr13_-_39075200 1.282 LHFP
lipoma HMGIC fusion partner
chr9_-_139437471 1.282 EXD3
exonuclease 3'-5' domain containing 3
chr3_+_50167424 1.273 SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr3_+_16901455 1.262 NM_001144382
PLCL2
phospholipase C-like 2
chr7_-_138316393 1.261 NM_001164665
NM_020910
KIAA1549

KIAA1549

chr1_-_1274160 1.254 NM_004421
DVL1
dishevelled, dsh homolog 1 (Drosophila)
chr7_-_81910956 1.251 NM_000722
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr17_-_8474733 1.251 NM_005964
MYH10
myosin, heavy chain 10, non-muscle
chr16_+_1763185 1.239 NM_001010865
EME2
essential meiotic endonuclease 1 homolog 2 (S. pombe)
chr13_-_40138607 1.238 NM_002015
FOXO1
forkhead box O1
chr15_+_29406335 1.237 NM_015995
KLF13
Kruppel-like factor 13
chr1_+_218930250 1.235 NM_024709
C1orf115
chromosome 1 open reading frame 115
chr14_+_85069217 1.235


chr5_+_132111034 1.232 NM_001039780
CCNI2
cyclin I family, member 2
chr10_+_124210980 1.232 NM_002775
HTRA1
HtrA serine peptidase 1
chr16_-_55016803 1.231 AMFR
autocrine motility factor receptor
chr9_-_131444098 1.231 NM_017873
NM_177999
ASB6

ankyrin repeat and SOCS box containing 6

chr1_-_15784048 1.220 NM_024758
AGMAT
agmatine ureohydrolase (agmatinase)
chr13_+_97593711 1.199 FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr2_+_28469199 1.198 FOSL2
FOS-like antigen 2
chr12_-_122584381 1.197 RILPL1
Rab interacting lysosomal protein-like 1
chr2_-_31214868 1.197


chr8_-_97242119 1.192 NM_001001557
GDF6
growth differentiation factor 6
chr21_+_41461962 1.191 BACE2
beta-site APP-cleaving enzyme 2
chr21_+_32706615 1.183 NM_058187
C21orf63
chromosome 21 open reading frame 63
chr5_-_45731588 1.179 HCN1
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr4_-_122213018 1.168 NM_024574
C4orf31
chromosome 4 open reading frame 31
chr3_+_61522310 1.165 PTPRG
protein tyrosine phosphatase, receptor type, G
chr7_-_81910740 1.164 CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr17_-_73867748 1.159 NM_003955
SOCS3
suppressor of cytokine signaling 3
chr12_-_122321640 1.158 CDK2AP1
cyclin-dependent kinase 2 associated protein 1
chr2_+_28469172 1.157 FOSL2
FOS-like antigen 2
chr12_-_29827952 1.154 NM_001193451
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chrX_-_57953578 1.149 NM_007156
ZXDA
zinc finger, X-linked, duplicated A
chr10_+_134060681 1.141 NM_001098637
NM_138499
PWWP2B

PWWP domain containing 2B

chr4_+_148872902 1.140 NM_024605
ARHGAP10
Rho GTPase activating protein 10
chr11_-_787955 1.139 NM_001191060
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr20_+_13150417 1.137 NM_080826
ISM1
isthmin 1 homolog (zebrafish)
chr19_+_1397268 1.135 APC2
adenomatosis polyposis coli 2
chr11_+_119887630 1.134 LOC100293636
GRIK4
hypothetical protein LOC100293636
glutamate receptor, ionotropic, kainate 4
chr19_+_54309423 1.131 NM_022165
LIN7B
lin-7 homolog B (C. elegans)
chr6_+_53767251 1.127 LRRC1
leucine rich repeat containing 1
chr18_-_490583 1.124 NM_130386
COLEC12
collectin sub-family member 12
chr20_-_3714905 1.119 NM_001810
CENPB
centromere protein B, 80kDa
chr19_+_7651706 1.118 NM_001042462
TRAPPC5
trafficking protein particle complex 5
chr2_-_230287442 1.113 NM_139072
DNER
delta/notch-like EGF repeat containing
chr15_+_97010219 1.110 NM_000875
IGF1R
insulin-like growth factor 1 receptor
chr11_-_114880275 1.110 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr10_+_6284845 1.109 NM_004566
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr10_-_44200458 1.106 NM_000609
NM_001033886
NM_001178134
NM_199168
CXCL12



chemokine (C-X-C motif) ligand 12



chr6_-_13595751 1.099 NM_018988
GFOD1
glucose-fructose oxidoreductase domain containing 1
chr13_-_29067795 1.098 NM_003045
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr12_-_122322117 1.096 NM_004642
CDK2AP1
cyclin-dependent kinase 2 associated protein 1
chr11_-_2863536 1.089 NM_000076
NM_001122630
NM_001122631
CDKN1C


cyclin-dependent kinase inhibitor 1C (p57, Kip2)


chr4_+_3738093 1.086 NM_000683
ADRA2C
adrenergic, alpha-2C-, receptor
chr8_-_134653194 1.086 NM_003033
NM_173344
ST3GAL1

ST3 beta-galactoside alpha-2,3-sialyltransferase 1

chr10_+_124211353 1.079 HTRA1
HtrA serine peptidase 1
chr22_-_41913075 1.079 TTLL12
tubulin tyrosine ligase-like family, member 12
chr9_-_133396444 1.078 NM_001135954
NM_031432
UCK1

uridine-cytidine kinase 1

chr22_+_35745740 1.077 MPST
mercaptopyruvate sulfurtransferase
chrX_+_149282097 1.075 NM_001177465
MAMLD1
mastermind-like domain containing 1
chr12_+_131774225 1.066 NM_018663
PXMP2
peroxisomal membrane protein 2, 22kDa
chr11_-_17366781 1.064 NM_000525
KCNJ11
potassium inwardly-rectifying channel, subfamily J, member 11
chr21_+_44699796 1.060 NM_030891
LRRC3
leucine rich repeat containing 3
chr17_-_60346042 1.058 LRRC37A3
leucine rich repeat containing 37, member A3
chr17_+_32924049 1.058 NM_007026
DUSP14
dual specificity phosphatase 14
chr7_+_148590152 1.054 NM_001195220
ZNF783
zinc finger family member 783
chr10_-_30065760 1.052 SVIL
supervillin
chr2_+_85834111 1.052 NM_032827
ATOH8
atonal homolog 8 (Drosophila)
chr10_-_135088065 1.051 NM_001012508
SPRN
shadow of prion protein homolog (zebrafish)
chr17_-_59131194 1.044 LIMD2
LIM domain containing 2
chr9_+_115265827 1.040 NM_017790
RGS3
regulator of G-protein signaling 3
chr19_+_54309443 1.038 LIN7B
lin-7 homolog B (C. elegans)
chr12_-_131773972 1.037 NM_006231
POLE
polymerase (DNA directed), epsilon
chr2_+_242322645 1.033 NM_152783
D2HGDH
D-2-hydroxyglutarate dehydrogenase
chr2_-_110230822 1.032 MALL
mal, T-cell differentiation protein-like

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.51 2.38e-20 GO:0007399 nervous system development
1.59 1.96e-15 GO:0022008 neurogenesis
1.59 1.01e-14 GO:0048699 generation of neurons
1.26 1.93e-13 GO:0007275 multicellular organismal development
1.29 3.20e-13 GO:0048731 system development
1.09 1.36e-12 GO:0009987 cellular process
1.39 2.03e-12 GO:0023051 regulation of signaling
1.23 2.42e-12 GO:0032502 developmental process
1.25 3.45e-11 GO:0048856 anatomical structure development
1.38 8.50e-11 GO:0009653 anatomical structure morphogenesis
1.39 1.07e-10 GO:0009966 regulation of signal transduction
1.58 1.15e-10 GO:0030182 neuron differentiation
1.32 1.25e-10 GO:0030154 cell differentiation
1.30 2.29e-10 GO:0048523 negative regulation of cellular process
1.30 5.41e-10 GO:0048869 cellular developmental process
1.71 5.85e-10 GO:0048812 neuron projection morphogenesis
1.14 1.29e-09 GO:0050794 regulation of cellular process
1.65 1.44e-09 GO:0000904 cell morphogenesis involved in differentiation
1.12 1.59e-09 GO:0065007 biological regulation
1.55 1.59e-09 GO:0045595 regulation of cell differentiation
1.71 2.12e-09 GO:0007409 axonogenesis
1.27 4.21e-09 GO:0048519 negative regulation of biological process
1.68 5.64e-09 GO:0048667 cell morphogenesis involved in neuron differentiation
1.21 5.89e-09 GO:0023052 signaling
1.55 6.82e-09 GO:0007167 enzyme linked receptor protein signaling pathway
1.63 9.22e-09 GO:0031175 neuron projection development
1.45 1.57e-08 GO:0048468 cell development
1.12 1.65e-08 GO:0050789 regulation of biological process
1.76 2.57e-08 GO:0007411 axon guidance
1.44 7.16e-08 GO:0050793 regulation of developmental process
1.40 1.10e-07 GO:0010646 regulation of cell communication
1.59 1.16e-07 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.52 1.77e-07 GO:0032989 cellular component morphogenesis
1.55 2.31e-07 GO:0048666 neuron development
1.58 2.42e-07 GO:0048858 cell projection morphogenesis
1.58 2.70e-07 GO:0032990 cell part morphogenesis
1.51 3.85e-07 GO:0030030 cell projection organization
1.28 4.27e-07 GO:0048583 regulation of response to stimulus
1.53 4.36e-07 GO:0000902 cell morphogenesis
1.19 1.08e-06 GO:0007165 signal transduction
1.19 1.17e-06 GO:0016043 cellular component organization
1.24 1.26e-06 GO:0048522 positive regulation of cellular process
1.34 1.39e-06 GO:0051239 regulation of multicellular organismal process
1.70 1.56e-06 GO:0060284 regulation of cell development
1.68 1.90e-06 GO:0045597 positive regulation of cell differentiation
1.45 2.11e-06 GO:2000026 regulation of multicellular organismal development
1.22 3.51e-06 GO:0048518 positive regulation of biological process
1.56 6.08e-06 GO:0048646 anatomical structure formation involved in morphogenesis
1.59 7.62e-06 GO:0009968 negative regulation of signal transduction
1.18 7.71e-06 GO:0071840 cellular component organization or biogenesis
1.56 1.02e-05 GO:0023057 negative regulation of signaling
1.56 1.24e-05 GO:0010648 negative regulation of cell communication
1.56 1.37e-05 GO:0051094 positive regulation of developmental process
1.44 1.73e-05 GO:0009790 embryo development
1.70 2.22e-05 GO:0051960 regulation of nervous system development
1.74 2.44e-05 GO:0050767 regulation of neurogenesis
1.21 2.59e-05 GO:0071842 cellular component organization at cellular level
1.22 4.38e-05 GO:0042221 response to chemical stimulus
2.01 4.63e-05 GO:0030111 regulation of Wnt receptor signaling pathway
1.25 5.70e-05 GO:0007166 cell surface receptor linked signaling pathway
1.15 5.86e-05 GO:0051716 cellular response to stimulus
1.58 6.15e-05 GO:0043009 chordate embryonic development
1.49 1.31e-04 GO:0048585 negative regulation of response to stimulus
1.57 1.34e-04 GO:0009792 embryo development ending in birth or egg hatching
1.53 1.56e-04 GO:0040008 regulation of growth
1.34 1.57e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.48 1.66e-04 GO:0007417 central nervous system development
1.34 1.77e-04 GO:0042127 regulation of cell proliferation
1.44 1.93e-04 GO:0009887 organ morphogenesis
1.65 2.20e-04 GO:0035295 tube development
1.19 2.30e-04 GO:0071841 cellular component organization or biogenesis at cellular level
1.74 5.07e-04 GO:0045664 regulation of neuron differentiation
1.51 5.76e-04 GO:0008285 negative regulation of cell proliferation
1.52 6.42e-04 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.59 7.29e-04 GO:0022603 regulation of anatomical structure morphogenesis
1.93 7.45e-04 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.35 9.09e-04 GO:0051128 regulation of cellular component organization
1.91 1.03e-03 GO:0022604 regulation of cell morphogenesis
1.39 1.17e-03 GO:0042325 regulation of phosphorylation
1.34 1.26e-03 GO:0006351 transcription, DNA-dependent
1.67 1.44e-03 GO:0002009 morphogenesis of an epithelium
1.20 1.81e-03 GO:0065008 regulation of biological quality
1.98 2.21e-03 GO:0010720 positive regulation of cell development
1.53 2.64e-03 GO:0007389 pattern specification process
1.39 2.66e-03 GO:0001932 regulation of protein phosphorylation
1.37 2.78e-03 GO:0019220 regulation of phosphate metabolic process
1.37 2.78e-03 GO:0051174 regulation of phosphorus metabolic process
1.58 2.89e-03 GO:0001944 vasculature development
2.08 2.90e-03 GO:0060828 regulation of canonical Wnt receptor signaling pathway
1.30 2.95e-03 GO:0009605 response to external stimulus
1.63 3.01e-03 GO:0001558 regulation of cell growth
1.45 3.26e-03 GO:0072358 cardiovascular system development
1.45 3.26e-03 GO:0072359 circulatory system development
1.60 3.49e-03 GO:0045596 negative regulation of cell differentiation
1.10 3.66e-03 GO:0044237 cellular metabolic process
1.25 3.83e-03 GO:0035556 intracellular signal transduction
1.32 4.55e-03 GO:0040011 locomotion
1.36 5.17e-03 GO:0009719 response to endogenous stimulus
1.55 5.23e-03 GO:0048729 tissue morphogenesis
1.70 6.27e-03 GO:0035239 tube morphogenesis
3.54 6.28e-03 GO:0002040 sprouting angiogenesis
1.61 8.25e-03 GO:0003002 regionalization
1.35 8.39e-03 GO:0009890 negative regulation of biosynthetic process
1.52 9.10e-03 GO:0001501 skeletal system development
1.40 9.15e-03 GO:0051253 negative regulation of RNA metabolic process
1.40 1.05e-02 GO:0045892 negative regulation of transcription, DNA-dependent
1.35 1.06e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.37 1.33e-02 GO:0010629 negative regulation of gene expression
1.20 1.35e-02 GO:0006464 protein modification process
1.14 1.46e-02 GO:0031323 regulation of cellular metabolic process
1.14 1.51e-02 GO:0060255 regulation of macromolecule metabolic process
1.20 1.54e-02 GO:0048513 organ development
1.47 1.67e-02 GO:0007420 brain development
1.63 1.70e-02 GO:0001701 in utero embryonic development
1.36 1.99e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.45 2.12e-02 GO:0007264 small GTPase mediated signal transduction
1.12 2.13e-02 GO:0044260 cellular macromolecule metabolic process
1.24 2.22e-02 GO:0010033 response to organic substance
1.27 2.23e-02 GO:0006793 phosphorus metabolic process
1.27 2.23e-02 GO:0006796 phosphate metabolic process
1.66 2.34e-02 GO:0014070 response to organic cyclic compound
1.36 2.52e-02 GO:0009725 response to hormone stimulus
2.01 2.58e-02 GO:0050769 positive regulation of neurogenesis
1.46 2.68e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.54 2.85e-02 GO:0001568 blood vessel development
1.13 2.98e-02 GO:0080090 regulation of primary metabolic process
1.19 3.20e-02 GO:0043412 macromolecule modification
1.48 3.84e-02 GO:0051093 negative regulation of developmental process
1.33 4.16e-02 GO:0010628 positive regulation of gene expression
1.38 4.27e-02 GO:0006935 chemotaxis
1.38 4.27e-02 GO:0042330 taxis
1.78 4.45e-02 GO:0010975 regulation of neuron projection development
1.09 4.49e-02 GO:0044238 primary metabolic process
1.34 4.52e-02 GO:0051172 negative regulation of nitrogen compound metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.09 6.87e-14 GO:0044424 intracellular part
1.08 2.40e-13 GO:0005622 intracellular
1.12 1.46e-11 GO:0005737 cytoplasm
1.03 6.35e-05 GO:0044464 cell part
1.03 6.77e-05 GO:0005623 cell
1.06 1.45e-03 GO:0043226 organelle
1.06 1.83e-03 GO:0043229 intracellular organelle
1.73 2.53e-03 GO:0005912 adherens junction
1.17 6.03e-03 GO:0005829 cytosol
1.06 6.42e-03 GO:0043227 membrane-bounded organelle
1.06 7.46e-03 GO:0043231 intracellular membrane-bounded organelle
1.17 7.87e-03 GO:0044459 plasma membrane part
1.09 8.32e-03 GO:0044444 cytoplasmic part
1.33 1.37e-02 GO:0030054 cell junction
1.40 1.53e-02 GO:0045202 synapse
1.61 2.15e-02 GO:0070161 anchoring junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.13 9.09e-11 GO:0005515 protein binding
1.07 1.53e-10 GO:0005488 binding
1.33 2.98e-05 GO:0001071 nucleic acid binding transcription factor activity
1.33 2.98e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.39 1.33e-04 GO:0043565 sequence-specific DNA binding
1.73 1.58e-04 GO:0010843 promoter binding
1.70 2.26e-04 GO:0000975 regulatory region DNA binding
1.70 2.26e-04 GO:0001067 regulatory region nucleic acid binding
1.70 2.26e-04 GO:0044212 transcription regulatory region DNA binding
1.30 3.07e-04 GO:0030528 transcription regulator activity
1.49 4.96e-03 GO:0016563 transcription activator activity
1.87 5.76e-03 GO:0019207 kinase regulator activity
1.46 8.23e-03 GO:0042578 phosphoric ester hydrolase activity
1.92 9.08e-03 GO:0019887 protein kinase regulator activity
1.94 1.89e-02 GO:0019199 transmembrane receptor protein kinase activity
1.26 2.20e-02 GO:0030234 enzyme regulator activity
1.50 3.90e-02 GO:0016791 phosphatase activity