Motif ID: NFIL3.p2

Z-value: 0.777


Transcription factors associated with NFIL3.p2:

Gene SymbolEntrez IDGene Name
NFIL3 4783 nuclear factor, interleukin 3 regulated

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFIL3chr9_-_93225961-0.758.9e-04Click!


Activity profile for motif NFIL3.p2.

activity profile for motif NFIL3.p2


Sorted Z-values histogram for motif NFIL3.p2

Sorted Z-values for motif NFIL3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFIL3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_3936460 0.992 NM_001961
EEF2
eukaryotic translation elongation factor 2
chr10_+_95838801 0.924 NM_001165979
PLCE1
phospholipase C, epsilon 1
chr6_+_72979234 0.909 NM_001168407
NM_001168408
RIMS1

regulating synaptic membrane exocytosis 1

chr22_+_42900168 0.788 NM_001137605
PARVG
parvin, gamma
chr17_-_46140015 0.783 NM_052855
ANKRD40
ankyrin repeat domain 40
chr9_-_94338072 0.720 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr22_-_34564611 0.718 RPL41P5
ribosomal protein L41 pseudogene 5
chr9_+_15542871 0.700 NM_173550
C9orf93
chromosome 9 open reading frame 93
chr1_+_24713396 0.690 RCAN3
RCAN family member 3
chr17_+_38250122 0.645 NM_001158
NM_009590
AOC2

amine oxidase, copper containing 2 (retina-specific)

chr10_+_18589589 0.582 NM_000724
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr7_-_31347032 0.581 NM_022728
NEUROD6
neurogenic differentiation 6
chr14_+_61532293 0.574 NM_031914
SYT16
synaptotagmin XVI
chr9_+_27514311 0.550 NM_020124
IFNK
interferon, kappa
chr14_-_76958984 0.545 NM_138791
NM_001113475
C14orf148

chromosome 14 open reading frame 148

chr4_-_74307637 0.527 ANKRD17
ankyrin repeat domain 17
chr13_-_32678142 0.514 NM_052851
STARD13
StAR-related lipid transfer (START) domain containing 13
chr12_+_54316910 0.492 NM_206899
OR10P1
olfactory receptor, family 10, subfamily P, member 1
chr1_+_11171967 0.482 NM_021146
ANGPTL7
angiopoietin-like 7
chr1_+_47305633 0.482 NM_178134
CYP4Z1
cytochrome P450, family 4, subfamily Z, polypeptide 1
chr20_-_48980858 0.475 NM_015339
NM_181442
ADNP

activity-dependent neuroprotector homeobox

chr5_-_137876416 0.469 ETF1
eukaryotic translation termination factor 1
chr5_+_140227951 0.467 NM_018902
NM_031861
PCDHA11

protocadherin alpha 11

chrX_+_41191630 0.458 NM_022567
NYX
nyctalopin
chr7_+_89681069 0.451 NM_001040666
STEAP2
six transmembrane epithelial antigen of the prostate 2
chr4_+_47403107 0.450


chr6_-_133076873 0.442 NM_004666
VNN1
vanin 1
chr2_-_178461710 0.439 NM_001077196
PDE11A
phosphodiesterase 11A
chr4_+_146820805 0.427 NM_001080531
C4orf51
chromosome 4 open reading frame 51
chr8_-_11891168 0.423 NM_001033019
DEFB134
defensin, beta 134
chr4_+_88187215 0.420 AFF1
AF4/FMR2 family, member 1
chr11_+_35596310 0.416 NM_014344
FJX1
four jointed box 1 (Drosophila)
chr7_-_111216180 0.416 DOCK4
dedicator of cytokinesis 4
chr11_+_122936246 0.396 GRAMD1B
GRAM domain containing 1B
chr5_-_94443300 0.389 NM_001002796
MCTP1
multiple C2 domains, transmembrane 1
chr10_-_95350949 0.382 NM_006744
RBP4
retinol binding protein 4, plasma
chr9_+_17568952 0.380 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr15_-_47042932 0.379 NM_203349
SHC4
SHC (Src homology 2 domain containing) family, member 4
chr1_-_6218576 0.374 ICMT
isoprenylcysteine carboxyl methyltransferase
chr10_+_91077581 0.369 NM_001549
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr17_+_36515166 0.349 NM_001146041
KRTAP4-9
keratin associated protein 4-9
chr11_-_10487212 0.347 NM_001190702
MTRNR2L8
MT-RNR2-like 8
chr11_+_122936145 0.347 GRAMD1B
GRAM domain containing 1B
chr17_-_59204622 0.347 CCDC47
coiled-coil domain containing 47
chr21_+_17841297 0.343 CXADR
coxsackie virus and adenovirus receptor
chr13_+_96797290 0.342


chr5_-_52441044 0.332 NM_004531
MOCS2
molybdenum cofactor synthesis 2
chr4_+_3341521 0.332 NM_198227
RGS12
regulator of G-protein signaling 12
chr2_-_99472843 0.329 REV1
REV1 homolog (S. cerevisiae)
chr17_-_38979178 0.326 NM_001079675
ETV4
ets variant 4
chr3_-_195670256 0.322 NM_024524
ATP13A3
ATPase type 13A3
chr7_-_122627235 0.304 NM_022444
SLC13A1
solute carrier family 13 (sodium/sulfate symporters), member 1
chr1_-_6218554 0.300 ICMT
isoprenylcysteine carboxyl methyltransferase
chr14_+_19458580 0.297 NM_001005483
OR4K5
olfactory receptor, family 4, subfamily K, member 5
chr17_-_59204685 0.296 NM_020198
CCDC47
coiled-coil domain containing 47
chr2_+_201464884 0.293 NM_001142356
NIF3L1
NIF3 NGG1 interacting factor 3-like 1 (S. pombe)
chr7_-_143597313 0.288 NM_198495
CTAGE4
CTAGE8
CTAGE family, member 4
CTAGE family, member 8
chr3_-_78749633 0.285 ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr18_+_30875297 0.285 NM_014268
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr19_+_46189022 0.281 NM_000767
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr2_+_148319033 0.281 NM_001616
ACVR2A
activin A receptor, type IIA
chr12_-_51360439 0.278 NM_006121
KRT1
keratin 1
chr3_+_130014957 0.275 RAB7A
RAB7A, member RAS oncogene family
chr8_-_17599438 0.272 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr4_+_74921136 0.270 NM_002993
CXCL6
chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)
chr7_-_141048358 0.266 NM_001080392
KIAA1147
KIAA1147
chr17_-_36528113 0.259 NM_033059
KRTAP4-11
keratin associated protein 4-11
chr20_+_36643251 0.259 NM_001018082
ADIG
adipogenin
chr12_-_7487989 0.259 NM_174941
CD163L1
CD163 molecule-like 1
chr17_-_60439764 0.248 GNA13
guanine nucleotide binding protein (G protein), alpha 13
chr12_-_123568781 0.248


chr15_-_63871492 0.245 DENND4A
DENN/MADD domain containing 4A
chr16_+_7322751 0.243 NM_145891
NM_145892
NM_145893
RBFOX1


RNA binding protein, fox-1 homolog (C. elegans) 1


chr2_-_40510923 0.242 NM_001112800
NM_001112801
NM_021097
SLC8A1


solute carrier family 8 (sodium/calcium exchanger), member 1


chrX_-_131375217 0.238 NM_001170701
NM_001170702
NM_001170703
MBNL3


muscleblind-like 3 (Drosophila)


chr10_+_85994788 0.237 NM_001012720
NM_001012722
NM_002921
RGR


retinal G protein coupled receptor


chr4_-_70115037 0.235 NM_001073
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr2_-_99472910 0.234 NM_001037872
NM_016316
REV1

REV1 homolog (S. cerevisiae)

chr5_-_79982584 0.233 NM_001190470
MTRNR2L2
MT-RNR2-like 2
chr5_+_175041069 0.229 NM_022304
HRH2
histamine receptor H2
chr1_-_151614681 0.225 NM_005621
S100A12
S100 calcium binding protein A12
chrX_+_38548016 0.225 NM_021242
MID1IP1
MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))
chr7_+_115650240 0.224 NM_152829
TES
testis derived transcript (3 LIM domains)
chr10_+_98054074 0.224 NM_001017520
NM_004088
DNTT

deoxynucleotidyltransferase, terminal

chr3_+_62280435 0.223 NM_020685
C3orf14
chromosome 3 open reading frame 14
chr9_-_103237851 0.223 NM_000035
ALDOB
aldolase B, fructose-bisphosphate
chr1_-_54183833 0.222 NM_016126
HSPB11
heat shock protein family B (small), member 11
chr1_+_7766966 0.219 PER3
period homolog 3 (Drosophila)
chr1_+_40611955 0.216 NM_022733
SMAP2
small ArfGAP2
chr7_-_37923040 0.214 NM_003014
SFRP4
secreted frizzled-related protein 4
chr12_+_58369392 0.214 NM_004731
SLC16A7
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr1_+_161305188 0.211 NM_005613
RGS4
regulator of G-protein signaling 4
chr22_+_40416492 0.211 NM_001142964
C22orf46
chromosome 22 open reading frame 46
chr11_+_6823458 0.206 NM_178168
OR10A5
olfactory receptor, family 10, subfamily A, member 5
chr1_+_40612016 0.204 SMAP2
small ArfGAP2
chr5_-_147996769 0.198 NM_001040169
NM_001040172
NM_001040173
NM_199453
HTR4



5-hydroxytryptamine (serotonin) receptor 4



chr17_+_36493927 0.195 NM_033061
KRTAP4-7
keratin associated protein 4-7
chr13_+_96672541 0.193 NM_144778
NM_207304
MBNL2

muscleblind-like 2 (Drosophila)

chr11_+_93394025 0.191 NM_001098672
HEPHL1
hephaestin-like 1
chr17_+_55269974 0.190


chr11_-_83661878 0.189 NM_001142700
DLG2
discs, large homolog 2 (Drosophila)
chr10_-_14412813 0.187 NM_018027
FRMD4A
FERM domain containing 4A
chr17_+_55098280 0.185 CLTC
clathrin, heavy chain (Hc)
chr17_-_34209671 0.183 NM_003559
PIP4K2B
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr5_+_86712376 0.182


chr4_-_96689373 0.181 NM_003728
UNC5C
unc-5 homolog C (C. elegans)
chr6_+_154449334 0.181 NM_001145287
OPRM1
opioid receptor, mu 1
chr2_-_202811459 0.181 NM_001005781
NM_001005782
NM_003352
SUMO1


SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)


chr1_-_177106702 0.178 NM_004673
ANGPTL1
angiopoietin-like 1
chr5_-_94442941 0.172 MCTP1
multiple C2 domains, transmembrane 1
chr6_-_26151863 0.172 NM_021062
HIST1H2BB
histone cluster 1, H2bb
chr1_+_57093030 0.170 NM_000562
C8A
complement component 8, alpha polypeptide
chr12_-_90029328 0.169 LUM
lumican
chr6_+_7347878 0.167 NM_153005
RIOK1
RIO kinase 1 (yeast)
chr2_-_86276102 0.166 IMMT
inner membrane protein, mitochondrial
chr13_-_37070862 0.165 NM_001135934
NM_001135935
NM_001135936
NM_006475
POSTN



periostin, osteoblast specific factor



chr6_-_132073849 0.164 NM_001145659
CTAGE9
CTAGE family, member 9
chr1_+_194887630 0.164 NM_000186
NM_001014975
CFH

complement factor H

chr19_+_46189124 0.163 CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr2_-_127817143 0.163 NM_006609
MAP3K2
mitogen-activated protein kinase kinase kinase 2
chr19_+_46286207 0.162 NM_000766
CYP2A13
cytochrome P450, family 2, subfamily A, polypeptide 13
chr21_-_30796278 0.162 NM_181611
KRTAP19-5
keratin associated protein 19-5
chr1_-_42157077 0.159 NM_001127714
NM_024503
HIVEP3

human immunodeficiency virus type I enhancer binding protein 3

chr1_+_86785346 0.159 NM_012128
CLCA4
chloride channel accessory 4
chr6_+_158654890 0.159


chr3_+_73193499 0.153 NM_018029
EBLN2
endogenous Borna-like N element-2
chr5_+_172415891 0.153 NM_001168393
NM_001168394
NM_153607
C5orf41


chromosome 5 open reading frame 41


chr9_+_71009746 0.152 NM_001170415
NM_001170416
TJP2

tight junction protein 2 (zona occludens 2)

chr19_-_58486686 0.152 NM_033341
BIRC8
baculoviral IAP repeat containing 8
chrX_-_77037563 0.152 NM_032121
MAGT1
magnesium transporter 1
chr16_-_54424517 0.151 NM_001025194
NM_001025195
NM_001266
CES1


carboxylesterase 1


chr9_+_96561750 0.150 NM_001193329
C9orf3
chromosome 9 open reading frame 3
chr2_-_188021117 0.150 NM_005795
CALCRL
calcitonin receptor-like
chr10_-_64698831 0.149 NM_004241
JMJD1C
jumonji domain containing 1C
chr3_-_192063158 0.145 NM_001146686
GEMC1
geminin coiled-coil domain-containing protein 1
chr1_+_202033273 0.144 NM_001174108
ZBED6
zinc finger, BED-type containing 6
chr3_+_171167243 0.142 NM_003262
SEC62
SEC62 homolog (S. cerevisiae)
chr8_-_91066060 0.141 NM_002485
NBN
nibrin
chr11_-_62539857 0.141 NM_001184732
NM_001184733
NM_001184736
NM_004254
SLC22A8



solute carrier family 22 (organic anion transporter), member 8



chr4_-_69218909 0.139 NM_001076
UGT2B15
UDP glucuronosyltransferase 2 family, polypeptide B15
chr15_+_91244422 0.138 NM_001042572
NM_001271
CHD2

chromodomain helicase DNA binding protein 2

chr10_-_82039158 0.137 NM_000429
MAT1A
methionine adenosyltransferase I, alpha
chr15_+_91244563 0.137 CHD2
chromodomain helicase DNA binding protein 2
chr6_-_123999640 0.134 NM_006073
TRDN
triadin
chr18_+_19826734 0.134 NM_153211
TTC39C
tetratricopeptide repeat domain 39C
chr7_+_134114701 0.134 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr4_-_186815116 0.134 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr6_+_167445284 0.133 NM_004367
CCR6
chemokine (C-C motif) receptor 6
chr22_-_48607199 0.133 BRD1
bromodomain containing 1
chr8_-_72437020 0.133 NM_000503
EYA1
eyes absent homolog 1 (Drosophila)
chr22_+_25347927 0.133 NM_001886
CRYBA4
crystallin, beta A4
chr1_+_144152864 0.129 TXNIP
thioredoxin interacting protein
chr9_+_83748234 0.129 NM_207416
FAM75D3
family with sequence similarity 75, member D3
chr12_+_15955499 0.129 DERA
deoxyribose-phosphate aldolase (putative)
chr11_+_64551472 0.127 NM_013306
NM_147777
SNX15

sorting nexin 15

chr17_-_1195096 0.127 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr4_+_77214886 0.127 NM_001130016
NM_001179
ART3

ADP-ribosyltransferase 3

chr1_+_227506751 0.126 NM_006542
SPHAR
S-phase response (cyclin related)
chr8_-_130868315 0.126 NM_031415
GSDMC
gasdermin C
chr2_-_192420168 0.125 NM_004657
SDPR
serum deprivation response
chr2_-_224611568 0.123 NM_001136530
SERPINE2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr8_+_67751007 0.123 NM_019607
C8orf44
chromosome 8 open reading frame 44
chr1_+_177261627 0.122 FAM20B
family with sequence similarity 20, member B
chr3_-_102888090 0.121 NM_000986
RPL24
ribosomal protein L24
chr21_-_14840506 0.117 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr1_+_148089251 0.117 NM_001040874
NM_003516
HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr9_+_32773496 0.116 NM_212558
TMEM215
transmembrane protein 215
chr10_+_90474280 0.116 NM_001080518
LIPK
lipase, family member K
chr8_-_102286695 0.116 ZNF706
zinc finger protein 706
chr1_+_177261678 0.116 NM_014864
FAM20B
family with sequence similarity 20, member B
chr9_-_32540818 0.114 TOPORS
topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
chr12_-_73889777 0.112 NM_139136
NM_139137
NM_153748
KCNC2


potassium voltage-gated channel, Shaw-related subfamily, member 2


chr1_+_210805319 0.111 NM_001030287
ATF3
activating transcription factor 3
chr2_+_161701711 0.111 NM_004180
NM_133484
TANK

TRAF family member-associated NFKB activator

chr7_+_143511480 0.110 NM_198495
CTAGE4
CTAGE8
CTAGE family, member 4
CTAGE family, member 8
chr5_+_140235114 0.109 NM_018903
NM_031864
PCDHA12

protocadherin alpha 12

chr6_-_66346417 0.109 NM_198283
EYS
eyes shut homolog (Drosophila)
chr6_-_132987106 0.109 NM_001033080
TAAR2
trace amine associated receptor 2
chr1_+_151081953 0.109 NM_001128600
LCE6A
late cornified envelope 6A
chr7_+_143646150 0.107 NM_001005287
NM_001001802
OR2A1
OR2A42
olfactory receptor, family 2, subfamily A, member 1
olfactory receptor, family 2, subfamily A, member 42
chr3_+_103029523 0.107 NM_001005474
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr2_+_169637255 0.106 NM_001142270
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr12_-_44407515 0.106 LOC400027
hypothetical LOC400027
chr2_-_86276015 0.105 IMMT
inner membrane protein, mitochondrial
chr6_+_64289585 0.105 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr1_+_176577228 0.105 NM_004841
RASAL2
RAS protein activator like 2
chr8_+_67568044 0.105 NM_152765
C8orf46
chromosome 8 open reading frame 46
chr12_+_54106304 0.103 NM_001005183
OR6C76
olfactory receptor, family 6, subfamily C, member 76
chr17_-_23965305 0.102 NM_001174103
SGK494
uncharacterized serine/threonine-protein kinase SgK494
chr7_+_142723340 0.102 NM_000083
CLCN1
chloride channel 1, skeletal muscle
chr2_-_45648608 0.102 SRBD1
S1 RNA binding domain 1
chr1_-_154988045 0.101 HDGF
hepatoma-derived growth factor
chr11_+_65026382 0.099


chr4_-_157006827 0.099 NM_017419
ACCN5
amiloride-sensitive cation channel 5, intestinal
chrX_+_79562601 0.098 NM_152630
FAM46D
family with sequence similarity 46, member D
chr3_+_188568861 0.098 NM_022147
RTP4
receptor (chemosensory) transporter protein 4
chr16_+_74868676 0.098 NM_033401
CNTNAP4
contactin associated protein-like 4
chr8_-_103735194 0.097 NM_001032282
KLF10
Kruppel-like factor 10
chrX_+_56772391 0.097 LOC550643
hypothetical LOC550643
chr4_+_70180805 0.094 NM_053039
UGT2B28
UDP glucuronosyltransferase 2 family, polypeptide B28

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.24 5.63e-03 GO:0008202 steroid metabolic process
5.23 1.02e-02 GO:0034754 cellular hormone metabolic process
1.52 4.86e-02 GO:0042221 response to chemical stimulus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
3.32 1.87e-03 GO:0045111 intermediate filament cytoskeleton
3.41 4.21e-03 GO:0005882 intermediate filament
1.55 5.30e-03 GO:0005576 extracellular region
1.79 1.16e-02 GO:0044421 extracellular region part
1.89 1.78e-02 GO:0005615 extracellular space
2.63 4.09e-02 GO:0042598 vesicular fraction

Gene overrepresentation in function category:

enrichment   p-value GO term description
26.71 2.83e-02 GO:0047023 androsterone dehydrogenase activity
5.48 3.00e-02 GO:0005507 copper ion binding
7.63 3.44e-02 GO:0016229 steroid dehydrogenase activity