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Motif ID: NKX3-2.p2

Z-value: 1.587

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_-_238861830	1.633	NM_022817	PER2	period homolog 2 (Drosophila)
chr8_+_32905027	1.546
chr2_+_17585462	1.463		VSNL1	visinin-like 1
chr2_+_228386800	1.401	NM_001130046 NM_004591	CCL20	chemokine (C-C motif) ligand 20
chr16_-_71650034	1.376	NM_001164766	ZFHX3	zinc finger homeobox 3
chr5_+_68746694	1.162	NM_001038603	MARVELD2	MARVEL domain containing 2
chr3_+_48482213	1.151	NM_016381 NM_033629	TREX1	three prime repair exonuclease 1
chr2_+_171280944	1.125		SP5	Sp5 transcription factor
chr16_+_55963883	1.111		CX3CL1	chemokine (C-X3-C motif) ligand 1
chr14_+_61653827	1.102		FLJ43390	hypothetical LOC646113
chr16_+_55963899	1.026	NM_002996	CX3CL1	chemokine (C-X3-C motif) ligand 1
chr14_-_20642214	1.010
chr2_+_17585287	0.982	NM_003385	VSNL1	visinin-like 1
chr2_-_136005238	0.972	NM_032143	ZRANB3	zinc finger, RAN-binding domain containing 3
chr3_+_48482625	0.963		TREX1	three prime repair exonuclease 1
chr3_+_106568430	0.960		ALCAM	activated leukocyte cell adhesion molecule
chr3_+_106568334	0.938	NM_001627	ALCAM	activated leukocyte cell adhesion molecule
chr14_-_22840249	0.896
chr14_+_30098079	0.894	NM_017769	G2E3	G2/M-phase specific E3 ubiquitin protein ligase
chr3_+_106568243	0.886		ALCAM	activated leukocyte cell adhesion molecule
chr8_+_123863075	0.866	NM_014943	ZHX2	zinc fingers and homeoboxes 2
chr10_-_105604942	0.865	NM_014631	SH3PXD2A	SH3 and PX domains 2A
chr14_-_23781328	0.859		TINF2	TERF1 (TRF1)-interacting nuclear factor 2
chr16_-_66523255	0.857	NM_001907	CTRL	chymotrypsin-like
chr17_+_55854636	0.853	NM_181707	C17orf64	chromosome 17 open reading frame 64
chr8_-_145132582	0.844	NM_032789	PARP10	poly (ADP-ribose) polymerase family, member 10
chr12_+_79995927	0.837	NM_024560	ACSS3	acyl-CoA synthetase short-chain family member 3
chr2_+_148495043	0.808	NM_018328	MBD5	methyl-CpG binding domain protein 5
chr13_+_112825113	0.804	NM_000504	F10	coagulation factor X
chr20_-_21442663	0.803	NM_002509	NKX2-2	NK2 homeobox 2
chr2_+_136005423	0.799	NM_015361	R3HDM1	R3H domain containing 1
chr8_+_123863169	0.790		ZHX2	zinc fingers and homeoboxes 2
chr2_-_70634129	0.785	NM_001099691 NM_003236	TGFA	transforming growth factor, alpha
chr5_+_35653702	0.744	NM_024867 NM_144722	SPEF2	sperm flagellar 2
chr10_+_123862430	0.740		TACC2	transforming, acidic coiled-coil containing protein 2
chr6_+_32114060	0.738	NM_000500 NM_001128590	CYP21A2	cytochrome P450, family 21, subfamily A, polypeptide 2
chr2_+_85665041	0.735	NM_006634	VAMP5	vesicle-associated membrane protein 5 (myobrevin)
chr12_+_56406296	0.730		LOC100130776	hypothetical LOC100130776
chr14_-_34414277	0.727		BAZ1A	bromodomain adjacent to zinc finger domain, 1A
chr13_+_75232797	0.725	NM_015842	LMO7	LIM domain 7
chr1_-_94779727	0.721	NM_001178096 NM_001993	F3	coagulation factor III (thromboplastin, tissue factor)
chr6_-_52060327	0.719	NM_138694 NM_170724	PKHD1	polycystic kidney and hepatic disease 1 (autosomal recessive)
chr16_+_49139694	0.715	NM_033119	NKD1	naked cuticle homolog 1 (Drosophila)
chr12_-_47604930	0.708	NM_001143781	FKBP11	FK506 binding protein 11, 19 kDa
chr2_+_201462294	0.700	NM_001136039 NM_001142355 NM_021824	NIF3L1	NIF3 NGG1 interacting factor 3-like 1 (S. pombe)
chr7_+_29200636	0.684	NM_004067	CHN2	chimerin (chimaerin) 2
chr14_-_23874083	0.679	NM_001198568 NM_001198592 NM_139247	ADCY4	adenylate cyclase 4
chr20_-_22513050	0.670	NM_021784	FOXA2	forkhead box A2
chr20_-_49852353	0.670	NM_020436	SALL4	sal-like 4 (Drosophila)
chr2_+_101981888	0.668	NM_173343	IL1R2	interleukin 1 receptor, type II
chr17_+_43165608	0.666	NM_013351	TBX21	T-box 21
chr16_-_87244896	0.664	NM_000101	CYBA	cytochrome b-245, alpha polypeptide
chr2_-_74588293	0.657	NM_032673	PCGF1	polycomb group ring finger 1
chr16_+_65790514	0.654	NM_024712	ELMO3	engulfment and cell motility 3
chr6_+_131190237	0.648	NM_001195597	LOC285733	hypothetical LOC285733
chr5_-_121440704	0.647	NM_001178102	LOX	lysyl oxidase
chr4_+_114190233	0.646	NM_001148 NM_020977	ANK2	ankyrin 2, neuronal
chr20_-_33793507	0.635		RBM39	RNA binding motif protein 39
chr9_+_77695334	0.633	NM_001190482 NM_006200	PCSK5	proprotein convertase subtilisin/kexin type 5
chr12_+_94861201	0.630	NM_152435	AMDHD1	amidohydrolase domain containing 1
chr6_-_16869579	0.629	NM_000332 NM_001128164	ATXN1	ataxin 1
chr14_-_34414241	0.627		BAZ1A	bromodomain adjacent to zinc finger domain, 1A
chr14_-_34414201	0.626		BAZ1A	bromodomain adjacent to zinc finger domain, 1A
chr16_-_87535106	0.624	NM_175931	CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr6_-_138935359	0.623	NM_020464	NHSL1	NHS-like 1
chr2_-_75641535	0.620		FAM176A	family with sequence similarity 176, member A
chr3_-_55490442	0.619		WNT5A	wingless-type MMTV integration site family, member 5A
chr6_+_26153590	0.613	NM_003531	HIST1H3C	histone cluster 1, H3c
chr20_-_22512893	0.609		FOXA2	forkhead box A2
chr19_+_40322231	0.607	NM_005031	FXYD1	FXYD domain containing ion transport regulator 1
chr12_+_14409875	0.597	NM_018179	ATF7IP	activating transcription factor 7 interacting protein
chr6_-_128883125	0.596	NM_002844 NM_001135648	PTPRK	protein tyrosine phosphatase, receptor type, K
chr20_-_33793591	0.589		RBM39	RNA binding motif protein 39
chr3_-_191522886	0.588	NM_021101	CLDN1	claudin 1
chr2_-_197499584	0.583	NM_024989	PGAP1	post-GPI attachment to proteins 1
chr2_-_37727472	0.578		CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3
chr15_+_97462675	0.572	NM_015286 NM_145728	SYNM	synemin, intermediate filament protein
chr19_-_4468715	0.571	NM_001080400	PLIN4	perilipin 4
chr10_-_123343761	0.561	NM_001144916	FGFR2	fibroblast growth factor receptor 2
chr14_+_20527971	0.560		METTL17	methyltransferase like 17
chr1_-_94475840	0.558	NM_004815	ARHGAP29	Rho GTPase activating protein 29
chr2_+_201099093	0.558	NM_001160033 NM_001160046 NM_152524	SGOL2	shugoshin-like 2 (S. pombe)
chr7_-_11838260	0.556	NM_015204	THSD7A	thrombospondin, type I, domain containing 7A
chr20_-_42249631	0.550	NM_020433 NM_175913	JPH2	junctophilin 2
chr2_-_168812132	0.542	NM_013233	STK39	serine threonine kinase 39
chr14_-_20642629	0.541	NM_001102454	ZNF219	zinc finger protein 219
chr14_-_22127902	0.541		DAD1	defender against cell death 1
chr17_-_70131389	0.541	NM_181449	CD300E	CD300e molecule
chr3_+_2115449	0.535		CNTN4	contactin 4
chr8_+_121206478	0.531	NM_021110	COL14A1	collagen, type XIV, alpha 1
chr22_+_39404940	0.531	NM_005297	MCHR1	melanin-concentrating hormone receptor 1
chr2_-_75641587	0.529	NM_001135032	FAM176A	family with sequence similarity 176, member A
chr1_-_94475504	0.525		ARHGAP29	Rho GTPase activating protein 29
chr3_+_113061330	0.524		PHLDB2	pleckstrin homology-like domain, family B, member 2
chr2_+_96295751	0.522		CIAO1	cytosolic iron-sulfur protein assembly 1
chr14_-_53491019	0.521	NM_130851	BMP4	bone morphogenetic protein 4
chr2_+_225973845	0.519	NM_020864	KIAA1486	KIAA1486
chr6_-_41823056	0.517	NM_001166424 NM_002630	PGC	progastricsin (pepsinogen C)
chr9_+_111582317	0.514	NM_053016 NM_007203 NM_147150	PALM2 PALM2-AKAP2	paralemmin 2 PALM2-AKAP2 readthrough
chr8_+_120497732	0.513	NM_002514	NOV	nephroblastoma overexpressed gene
chr6_-_149847809	0.511	NM_207360	ZC3H12D	zinc finger CCCH-type containing 12D
chr10_-_16604009	0.511	NM_001010908	C1QL3	complement component 1, q subcomponent-like 3
chr8_+_85258007	0.510	NM_001100392 NM_001100393	RALYL	RALY RNA binding protein-like
chr14_-_34413831	0.506		BAZ1A	bromodomain adjacent to zinc finger domain, 1A
chr8_+_11599119	0.506	NM_002052	GATA4	GATA binding protein 4
chr12_-_15265490	0.505	NM_001190726 NM_032918	RERG	RAS-like, estrogen-regulated, growth inhibitor
chr12_-_6355165	0.504	NM_001038	SCNN1A	sodium channel, nonvoltage-gated 1 alpha
chr3_-_55490401	0.503		WNT5A	wingless-type MMTV integration site family, member 5A
chr17_+_71154240	0.502	NM_001162997	LOC100130933	hypothetical protein LOC100130933
chr6_+_96570565	0.499	NM_006581	FUT9	fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
chr12_+_51979721	0.499	NM_021640	C12orf10	chromosome 12 open reading frame 10
chr4_+_89597257	0.499	NM_016323	HERC5	hect domain and RLD 5
chr8_-_122722674	0.497	NM_005328	HAS2	hyaluronan synthase 2
chr3_-_81893604	0.494	NM_000158	GBE1	glucan (1,4-alpha-), branching enzyme 1
chr2_+_238200922	0.492	NM_001137550	LRRFIP1	leucine rich repeat (in FLII) interacting protein 1
chrX_+_38305634	0.491	NM_004615	TSPAN7	tetraspanin 7
chr13_-_110066694	0.489
chr20_+_2309553	0.489	NM_198994	TGM6	transglutaminase 6
chr2_-_96295443	0.488		TMEM127	transmembrane protein 127
chr14_-_34943574	0.488	NM_020529	NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr5_-_134899537	0.486	NM_006161	NEUROG1	neurogenin 1
chr7_-_100751643	0.485	NM_001130820 NM_001130821 NM_001130822 NM_022777	RABL5	RAB, member RAS oncogene family-like 5
chr10_-_71575953	0.485		TYSND1	trypsin domain containing 1
chr10_+_59942874	0.485	NM_001080512	BICC1	bicaudal C homolog 1 (Drosophila)
chr20_-_1922701	0.485	NM_001190899 NM_001190898 NM_024411	PDYN	prodynorphin
chr3_-_121445831	0.481	NM_001168271 NM_153002	GPR156	G protein-coupled receptor 156
chr2_-_101134146	0.481	NM_001102426	TBC1D8	TBC1 domain family, member 8 (with GRAM domain)
chr10_+_96295511	0.478	NM_018063	HELLS	helicase, lymphoid-specific
chr16_-_67930974	0.475	NM_032382	COG8	component of oligomeric golgi complex 8
chr17_-_40348378	0.474	NM_001131019 NM_002055	GFAP	glial fibrillary acidic protein
chr14_-_21014871	0.474	NM_032846	RAB2B	RAB2B, member RAS oncogene family
chr4_-_164754106	0.472	NM_017923	MARCH1	membrane-associated ring finger (C3HC4) 1
chr17_+_18796202	0.471	NM_001042450 NM_152351	SLC5A10	solute carrier family 5 (sodium/glucose cotransporter), member 10
chr3_+_113061218	0.469	NM_001134439	PHLDB2	pleckstrin homology-like domain, family B, member 2
chr17_-_31332568	0.469	NM_004590	CCL16	chemokine (C-C motif) ligand 16
chr20_-_33793593	0.467	NM_004902 NM_184234	RBM39	RNA binding motif protein 39
chr20_+_43425153	0.464	NM_001099791 NM_033542	SYS1-DBNDD2 SYS1	SYS1-DBNDD2 read-through transcript SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr20_-_16501911	0.464	NM_024704	KIF16B	kinesin family member 16B
chr12_+_54361596	0.461	NM_152637	METTL7B	methyltransferase like 7B
chr5_-_35083996	0.459	NM_031900	AGXT2	alanine--glyoxylate aminotransferase 2
chr16_-_80602546	0.458	NM_145168	SDR42E1	short chain dehydrogenase/reductase family 42E, member 1
chr3_+_112876212	0.457	NM_001185106 NM_153268	PLCXD2	phosphatidylinositol-specific phospholipase C, X domain containing 2
chr16_-_28528780	0.456	NM_001055 NM_177529	SULT1A1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr12_-_47605478	0.455	NM_001143782 NM_016594	FKBP11	FK506 binding protein 11, 19 kDa
chr19_-_53365371	0.453	NM_000234	LIG1	ligase I, DNA, ATP-dependent
chr2_-_201461945	0.453	NM_032472 NM_130906	PPIL3	peptidylprolyl isomerase (cyclophilin)-like 3
chr2_+_218833982	0.452	NM_001077191 NM_001077194 NM_170699	GPBAR1	G protein-coupled bile acid receptor 1
chr7_+_90177082	0.452		CDK14	cyclin-dependent kinase 14
chr12_+_54361685	0.451		METTL7B	methyltransferase like 7B
chr14_-_23686269	0.450		PSME2	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr16_-_45735403	0.449	NM_018092	NETO2	neuropilin (NRP) and tolloid (TLL)-like 2
chr14_+_23633101	0.449	NM_001018073 NM_004563	PCK2	phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr11_+_12355600	0.448	NM_018222	PARVA	parvin, alpha
chr11_-_122357545	0.447	NM_001098169	BSX	brain-specific homeobox
chr3_+_113061296	0.447		PHLDB2	pleckstrin homology-like domain, family B, member 2
chr22_-_22714230	0.447	NM_000853	GSTT1	glutathione S-transferase theta 1
chr14_+_23700261	0.446	NM_006084	IRF9	interferon regulatory factor 9
chr16_-_45735333	0.446		NETO2	neuropilin (NRP) and tolloid (TLL)-like 2
chr2_+_48395271	0.446	NM_002158	FOXN2	forkhead box N2
chr6_-_27387989	0.445	NM_033482	POM121L2	POM121 membrane glycoprotein-like 2
chr3_-_81893308	0.440		GBE1	glucan (1,4-alpha-), branching enzyme 1
chr2_-_148495642	0.440	NM_181742	ORC4	origin recognition complex, subunit 4
chr3_-_185578621	0.439	NM_000460 NM_001177597 NM_001177598	THPO	thrombopoietin
chr18_-_46068048	0.439		CXXC1	CXXC finger protein 1
chr13_+_25726755	0.437	NM_001260	CDK8	cyclin-dependent kinase 8
chr8_+_123863224	0.436		ZHX2	zinc fingers and homeoboxes 2
chr7_-_50596238	0.436	NM_000790	DDC	dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr9_-_124715392	0.435	NM_006626	ZBTB6	zinc finger and BTB domain containing 6
chr14_+_21015198	0.435		TOX4	TOX high mobility group box family member 4
chr2_-_24123726	0.432	NM_001142319 NM_025203	C2orf44	chromosome 2 open reading frame 44
chr14_+_71469538	0.430	NM_004296	RGS6	regulator of G-protein signaling 6
chr12_+_81604752	0.430		TMTC2	transmembrane and tetratricopeptide repeat containing 2
chr2_-_189752575	0.427	NM_000393	COL5A2	collagen, type V, alpha 2
chr3_-_114947330	0.426		NAA50	N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr14_-_21014666	0.420	NM_001163380	RAB2B	RAB2B, member RAS oncogene family
chr6_-_5952096	0.419		NRN1	neuritin 1
chr9_-_26882713	0.418	NM_001167575 NM_024828	C9orf82	chromosome 9 open reading frame 82
chr1_+_107484151	0.417	NM_001113226 NM_001113228 NM_014917	NTNG1	netrin G1
chr4_-_84475328	0.416	NM_001166498 NM_006665	HPSE	heparanase
chr2_-_191723978	0.414		STAT4	signal transducer and activator of transcription 4
chr2_-_68952006	0.413	NM_014482	BMP10	bone morphogenetic protein 10
chr2_-_220144427	0.413		OBSL1	obscurin-like 1
chr14_+_21015168	0.412	NM_014828	TOX4	TOX high mobility group box family member 4
chr6_-_149847718	0.412		ZC3H12D	zinc finger CCCH-type containing 12D
chr10_+_91451313	0.410	NM_016195	KIF20B	kinesin family member 20B
chr3_-_184363126	0.409		LAMP3	lysosomal-associated membrane protein 3
chr4_-_24641404	0.408	NM_018176	LGI2	leucine-rich repeat LGI family, member 2
chr20_+_5839973	0.408	NM_001819	CHGB	chromogranin B (secretogranin 1)
chr2_+_190753833	0.408	NM_001042519 NM_032321	C2orf88	chromosome 2 open reading frame 88
chr2_+_241903395	0.407	NM_001008491 NM_006155	SEPT2	septin 2
chr18_-_46068003	0.406		CXXC1	CXXC finger protein 1
chr7_+_96473225	0.405	NM_005222	DLX6	distal-less homeobox 6
chr2_-_74460933	0.405	NM_001135040 NM_001190837 NM_004082	DCTN1	dynactin 1
chr8_-_99375739	0.405	NM_024759	NIPAL2	NIPA-like domain containing 2
chr7_+_80145461	0.405		CD36	CD36 molecule (thrombospondin receptor)
chr3_-_81893492	0.404		GBE1	glucan (1,4-alpha-), branching enzyme 1
chr14_+_105024576	0.402		CRIP1	cysteine-rich protein 1 (intestinal)
chr2_+_219141761	0.402	NM_005444	RQCD1	RCD1 required for cell differentiation1 homolog (S. pombe)
chr2_-_74588006	0.401		PCGF1	polycomb group ring finger 1
chr9_-_21984329	0.400		CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.31	1.02e-03	GO:0007399	nervous system development
1.10	4.51e-03	GO:0065007	biological regulation
1.44	4.72e-03	GO:0045595	regulation of cell differentiation
1.45	7.84e-03	GO:0032989	cellular component morphogenesis
1.37	9.32e-03	GO:0022008	neurogenesis
1.23	9.36e-03	GO:0048869	cellular developmental process
1.36	1.01e-02	GO:0050793	regulation of developmental process
1.20	1.03e-02	GO:0048518	positive regulation of biological process
1.06	1.31e-02	GO:0009987	cellular process
1.63	1.38e-02	GO:0060284	regulation of cell development
1.10	1.44e-02	GO:0050789	regulation of biological process
1.36	1.92e-02	GO:0048699	generation of neurons
1.27	2.29e-02	GO:0009653	anatomical structure morphogenesis
1.22	2.48e-02	GO:0030154	cell differentiation
1.38	2.88e-02	GO:2000026	regulation of multicellular organismal development
1.20	3.15e-02	GO:0048519	negative regulation of biological process
1.43	3.23e-02	GO:0000902	cell morphogenesis

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.05	2.23e-02	GO:0044424	intracellular part
1.05	2.46e-02	GO:0005622	intracellular

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.13	2.17e-06	GO:0005515	protein binding
1.45	5.78e-03	GO:0008092	cytoskeletal protein binding
1.05	1.09e-02	GO:0005488	binding