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Motif ID: PAX2.p2

Z-value: 1.415

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr3_+_141136691	1.202	NM_022131	CLSTN2	calsyntenin 2
chr15_+_41597097	0.997	NM_002373	MAP1A	microtubule-associated protein 1A
chr16_+_2503994	0.993		ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr16_+_29726962	0.951		MAZ	MYC-associated zinc finger protein (purine-binding transcription factor)
chr11_+_66915997	0.907	NM_004584	RAD9A	RAD9 homolog A (S. pombe)
chr20_+_43953428	0.894		CTSA	cathepsin A
chr12_+_28234657	0.881
chr17_-_39556535	0.872	NM_001015053 NM_005474	HDAC5	histone deacetylase 5
chr10_+_69314347	0.864	NM_012238	SIRT1	sirtuin 1
chr17_-_39556483	0.859		HDAC5	histone deacetylase 5
chr16_-_5023914	0.803		NAGPA	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr16_-_5023934	0.802	NM_016256	NAGPA	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr10_-_3817418	0.801	NM_001160124 NM_001160125 NM_001300	KLF6	Kruppel-like factor 6
chr1_+_221168388	0.786	NM_032890	DISP1	dispatched homolog 1 (Drosophila)
chr1_+_159550789	0.767	NM_001035511 NM_001035512 NM_001035513 NM_003001	SDHC	succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
chrX_-_102205736	0.750		BEX1	brain expressed, X-linked 1
chr6_-_33493898	0.732		CUTA	cutA divalent cation tolerance homolog (E. coli)
chr17_-_38081967	0.715	NM_024927	PLEKHH3	pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr1_-_153477511	0.692		GBA	glucosidase, beta, acid
chr12_-_113330574	0.682	NM_000192 NM_080717	TBX5	T-box 5
chr11_-_107598538	0.679	NM_002519	NPAT	nuclear protein, ataxia-telangiectasia locus
chr2_-_176575171	0.672	NM_030650	KIAA1715	KIAA1715
chr19_-_10287673	0.671	NM_001031734	FDX1L	ferredoxin 1-like
chr17_-_7078304	0.667		DVL2	dishevelled, dsh homolog 2 (Drosophila)
chr6_-_33494042	0.656	NM_001014433 NM_001014837 NM_001014838 NM_001014840 NM_015921	CUTA	cutA divalent cation tolerance homolog (E. coli)
chr10_-_123347493	0.648	NM_000141 NM_001144917 NM_001144918 NM_001144919 NM_022970	FGFR2	fibroblast growth factor receptor 2
chr6_+_31016755	0.643	NM_080870	DPCR1	diffuse panbronchiolitis critical region 1
chr1_-_153477673	0.639	NM_001171812 NM_000157	GBA	glucosidase, beta, acid
chr1_+_152460381	0.624		UBAP2L	ubiquitin associated protein 2-like
chr11_-_107598472	0.623		NPAT	nuclear protein, ataxia-telangiectasia locus
chr15_+_57696200	0.618		GCNT3	glucosaminyl (N-acetyl) transferase 3, mucin type
chrX_-_102205752	0.614	NM_018476	BEX1	brain expressed, X-linked 1
chr12_+_15926681	0.613		STRAP	serine/threonine kinase receptor associated protein
chr16_+_56219802	0.602	NM_001145771 NM_001145772 NM_001145773 NM_201524 NM_201525	GPR56	G protein-coupled receptor 56
chr6_-_33493640	0.600		CUTA	cutA divalent cation tolerance homolog (E. coli)
chr12_-_8993460	0.589		M6PR	mannose-6-phosphate receptor (cation dependent)
chr11_+_61479182	0.569		BEST1	bestrophin 1
chr6_-_33493792	0.569		CUTA	cutA divalent cation tolerance homolog (E. coli)
chr3_+_141136896	0.569		CLSTN2	calsyntenin 2
chr5_+_148766632	0.567		LOC728264	hypothetical LOC728264
chr12_+_15926743	0.553		STRAP	serine/threonine kinase receptor associated protein
chr7_-_149201696	0.546		LOC401431	hypothetical LOC401431
chr17_-_75735354	0.546	NM_014740	EIF4A3	eukaryotic translation initiation factor 4A3
chr20_+_37024383	0.544	NM_001190809 NM_021931	DHX35	DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr13_+_112704077	0.539		MCF2L	MCF.2 cell line derived transforming sequence-like
chr17_-_7078399	0.538		DVL2	dishevelled, dsh homolog 2 (Drosophila)
chr17_+_75851984	0.529
chr6_+_127629677	0.524	NM_030963	RNF146	ring finger protein 146
chr1_+_32485404	0.519	NM_032648	FAM167B	family with sequence similarity 167, member B
chr1_-_152797760	0.514		UBE2Q1	ubiquitin-conjugating enzyme E2Q family member 1
chr19_-_41237486	0.513	NM_152658	THAP8	THAP domain containing 8
chr16_+_29726931	0.509		MAZ	MYC-associated zinc finger protein (purine-binding transcription factor)
chr16_+_87765661	0.504	NM_004933	CDH15	cadherin 15, type 1, M-cadherin (myotubule)
chr6_-_37061920	0.499		MTCH1	mitochondrial carrier homolog 1 (C. elegans)
chr6_-_32121784	0.499	NM_032470	TNXB	tenascin XB
chr7_-_45117797	0.490		TBRG4	transforming growth factor beta regulator 4
chr7_-_45117822	0.489	NM_004749 NM_030900 NM_199122	TBRG4	transforming growth factor beta regulator 4
chr11_-_59140192	0.487	NM_002556	OSBP	oxysterol binding protein
chr6_-_37061908	0.483		MTCH1	mitochondrial carrier homolog 1 (C. elegans)
chr6_+_36670113	0.483		SRSF3	serine/arginine-rich splicing factor 3
chr1_-_152797820	0.474		UBE2Q1	ubiquitin-conjugating enzyme E2Q family member 1
chr3_-_48569213	0.473	NM_004567	PFKFB4	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr6_+_89847183	0.472		PNRC1	proline-rich nuclear receptor coactivator 1
chr20_+_46971618	0.471	NM_006420	ARFGEF2	ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr6_+_36670117	0.464		SRSF3	serine/arginine-rich splicing factor 3
chr17_-_34603577	0.460		CACNB1	calcium channel, voltage-dependent, beta 1 subunit
chr16_+_30952350	0.458		STX4	syntaxin 4
chr16_+_30952382	0.452	NM_004604	STX4	syntaxin 4
chr6_+_89847019	0.450	NM_006813	PNRC1	proline-rich nuclear receptor coactivator 1
chr14_+_67156323	0.450	NM_001172	ARG2	arginase, type II
chr12_+_51932136	0.448	NM_032889	MFSD5	major facilitator superfamily domain containing 5
chr19_+_45996881	0.447	NM_080732	EGLN2	egl nine homolog 2 (C. elegans)
chr6_-_37061902	0.446		MTCH1	mitochondrial carrier homolog 1 (C. elegans)
chr1_-_202595666	0.444	NM_014935	PLEKHA6	pleckstrin homology domain containing, family A member 6
chr6_+_32229771	0.444		PPT2-EGFL8 PPT2	PPT2-EGFL8 read-through transcript palmitoyl-protein thioesterase 2
chr1_-_152797767	0.444		UBE2Q1	ubiquitin-conjugating enzyme E2Q family member 1
chr12_+_51932173	0.441		MFSD5	major facilitator superfamily domain containing 5
chr2_-_136311219	0.441	NM_002299	LCT	lactase
chr2_-_128285136	0.435		WDR33	WD repeat domain 33
chr20_+_35240844	0.434	NM_001135771 NM_002951	RPN2	ribophorin II
chr6_+_36670067	0.434	NM_003017	SRSF3	serine/arginine-rich splicing factor 3
chr14_+_67156405	0.434		ARG2	arginase, type II
chr6_-_37061924	0.431	NM_014341	MTCH1	mitochondrial carrier homolog 1 (C. elegans)
chr4_+_81337663	0.427	NM_001099403	PRDM8	PR domain containing 8
chr17_-_7078446	0.426	NM_004422	DVL2	dishevelled, dsh homolog 2 (Drosophila)
chr12_+_52696908	0.424	NM_014620 NM_153693	HOXC4 HOXC6	homeobox C4 homeobox C6
chr2_-_128285214	0.423	NM_001006622 NM_001006623 NM_018383	WDR33	WD repeat domain 33
chr12_+_70434927	0.423		RAB21	RAB21, member RAS oncogene family
chr2_+_135392857	0.421	NM_001241 NM_058241	CCNT2	cyclin T2
chr3_-_151963607	0.421		SIAH2	seven in absentia homolog 2 (Drosophila)
chr11_+_65236261	0.415		KAT5	K(lysine) acetyltransferase 5
chr1_+_210525397	0.414		PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha
chr6_-_37061897	0.411		MTCH1	mitochondrial carrier homolog 1 (C. elegans)
chr22_+_38213174	0.409	NM_001098270	MGAT3	mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr20_-_47965393	0.408		SPATA2	spermatogenesis associated 2
chr11_+_61279436	0.407	NM_013279	C11orf9	chromosome 11 open reading frame 9
chr12_+_55148567	0.406	NM_207344	SPRYD4	SPRY domain containing 4
chr19_-_40696393	0.404	NM_001126056 NM_001126057 NM_001126058 NM_001190347 NM_001190348 NM_001190349 NM_033317	DMKN	dermokine
chrX_-_100549444	0.401		GLA	galactosidase, alpha
chr6_+_18263514	0.400	NM_153042	KDM1B	lysine (K)-specific demethylase 1B
chr11_+_65236064	0.399	NM_006388 NM_182709 NM_182710	KAT5	K(lysine) acetyltransferase 5
chr12_+_15926554	0.399	NM_007178	STRAP	serine/threonine kinase receptor associated protein
chr8_-_71743973	0.398	NM_016027	LACTB2	lactamase, beta 2
chr16_+_2503915	0.397		ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr16_+_2504001	0.397		ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr1_+_200358594	0.395	NM_004767	GPR37L1	G protein-coupled receptor 37 like 1
chr15_+_57696016	0.395		GCNT3	glucosaminyl (N-acetyl) transferase 3, mucin type
chr9_-_103289154	0.394	NM_032342	C9orf125	chromosome 9 open reading frame 125
chr11_+_107598768	0.393	NM_000051	ATM	ataxia telangiectasia mutated
chr6_-_31938572	0.391	NM_000434	NEU1	sialidase 1 (lysosomal sialidase)
chr12_+_40117751	0.390	NM_013377	PDZRN4	PDZ domain containing ring finger 4
chr19_+_41237597	0.389	NM_001083961 NM_173636	WDR62	WD repeat domain 62
chr6_-_99979850	0.389	NM_015491 NM_032870	SFRS18	splicing factor, arginine/serine-rich 18
chr4_+_120029426	0.388	NM_001128933 NM_001128934 NM_133477	SYNPO2	synaptopodin 2
chr9_-_109291866	0.387	NM_004235	KLF4	Kruppel-like factor 4 (gut)
chr20_+_35240936	0.385		RPN2	ribophorin II
chr10_-_93382735	0.385		PPP1R3C	protein phosphatase 1, regulatory (inhibitor) subunit 3C
chr12_+_51932252	0.383		MFSD5	major facilitator superfamily domain containing 5
chr17_-_77474597	0.379	NM_032711	MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chr16_+_29725665	0.377
chr12_-_8993515	0.375	NM_002355	M6PR	mannose-6-phosphate receptor (cation dependent)
chr17_+_1586034	0.374		WDR81	WD repeat domain 81
chr2_+_54195913	0.374	NM_138448	ACYP2	acylphosphatase 2, muscle type
chr2_-_170259105	0.372	NM_001085447	C2orf77	chromosome 2 open reading frame 77
chr8_+_98772537	0.370		MTDH	metadherin
chr13_+_112704051	0.369		MCF2L	MCF.2 cell line derived transforming sequence-like
chr20_+_43953606	0.369		CTSA	cathepsin A
chr4_+_144325502	0.368	NM_032557	USP38	ubiquitin specific peptidase 38
chr20_+_2744947	0.366	NM_001167670	LOC100288797	hypothetical protein LOC100288797
chr6_-_31853027	0.365	NM_025258	C6orf27	chromosome 6 open reading frame 27
chr12_+_70434920	0.364	NM_014999	RAB21	RAB21, member RAS oncogene family
chr3_-_9895471	0.363		CIDEC	cell death-inducing DFFA-like effector c
chr17_+_37864466	0.363		ATP6V0A1	ATPase, H+ transporting, lysosomal V0 subunit a1
chr13_+_112704028	0.362		MCF2L	MCF.2 cell line derived transforming sequence-like
chr19_+_10673105	0.360	NM_031209	QTRT1	queuine tRNA-ribosyltransferase 1
chr17_+_37864441	0.357		ATP6V0A1	ATPase, H+ transporting, lysosomal V0 subunit a1
chr7_-_104696678	0.354	NM_182691	SRPK2	SRSF protein kinase 2
chr12_-_56432375	0.353		CDK4	cyclin-dependent kinase 4
chr17_+_37864401	0.352		ATP6V0A1	ATPase, H+ transporting, lysosomal V0 subunit a1
chr11_-_82460531	0.352	NM_014488	RAB30	RAB30, member RAS oncogene family
chr19_+_45996940	0.352		EGLN2	egl nine homolog 2 (C. elegans)
chr1_-_159413833	0.351	NM_003779	B4GALT3	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
chr6_-_37062193	0.351		MTCH1	mitochondrial carrier homolog 1 (C. elegans)
chr11_+_58103212	0.351		ZFP91-CNTF ZFP91	ZFP91-CNTF readthrough transcript zinc finger protein 91 homolog (mouse)
chrX_-_39921525	0.350	NM_001123383 NM_001123384	BCOR	BCL6 corepressor
chr16_-_87646856	0.350
chrX_-_7855400	0.349	NM_004650	PNPLA4	patatin-like phospholipase domain containing 4
chr17_+_37864423	0.346		ATP6V0A1	ATPase, H+ transporting, lysosomal V0 subunit a1
chr2_-_20115269	0.346	NM_014713	LAPTM4A	lysosomal protein transmembrane 4 alpha
chr9_-_89779180	0.345		CDK20	cyclin-dependent kinase 20
chr11_+_2881080	0.344		SLC22A18	solute carrier family 22, member 18
chr14_-_38971370	0.344	NM_203301	FBXO33	F-box protein 33
chr3_-_151963577	0.343		SIAH2	seven in absentia homolog 2 (Drosophila)
chr17_+_37864425	0.342		ATP6V0A1	ATPase, H+ transporting, lysosomal V0 subunit a1
chr6_+_17501589	0.342	NM_006366	CAP2	CAP, adenylate cyclase-associated protein, 2 (yeast)
chr17_+_37864383	0.342	NM_001130020 NM_001130021 NM_005177	ATP6V0A1	ATPase, H+ transporting, lysosomal V0 subunit a1
chr12_-_56432377	0.337		CDK4	cyclin-dependent kinase 4
chr17_+_37864431	0.336		ATP6V0A1	ATPase, H+ transporting, lysosomal V0 subunit a1
chr18_+_58533597	0.334	NM_194449	PHLPP1	PH domain and leucine rich repeat protein phosphatase 1
chr6_-_53321545	0.333		ELOVL5	ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)
chr12_-_121276513	0.333		DIABLO	diablo homolog (Drosophila)
chr17_+_56831951	0.332	NM_005994	TBX2	T-box 2
chr6_+_33044353	0.330
chr8_-_71743908	0.328		LACTB2	lactamase, beta 2
chr7_-_158304062	0.328		ESYT2	extended synaptotagmin-like protein 2
chr1_-_118273728	0.324	NM_001135589 NM_017686	GDAP2	ganglioside induced differentiation associated protein 2
chr15_-_47042932	0.324	NM_203349	SHC4	SHC (Src homology 2 domain containing) family, member 4
chr2_+_135392879	0.322		CCNT2	cyclin T2
chr1_-_6585268	0.321		KLHL21	kelch-like 21 (Drosophila)
chr12_-_90096275	0.321	NM_133504 NM_133505 NM_133506 NM_133507	DCN	decorin
chr1_-_118273701	0.321		GDAP2	ganglioside induced differentiation associated protein 2
chr19_-_41236959	0.320		THAP8	THAP domain containing 8
chr1_-_155374756	0.319		ETV3	ets variant 3
chr17_-_59204622	0.318		CCDC47	coiled-coil domain containing 47
chr11_-_74740298	0.317	NM_004041 NM_020251	ARRB1	arrestin, beta 1
chr20_+_61337679	0.317	NM_022161 NM_139317	BIRC7	baculoviral IAP repeat containing 7
chr22_+_18388633	0.317		C22orf25	chromosome 22 open reading frame 25
chr3_+_11153778	0.316	NM_001098213	HRH1	histamine receptor H1
chr3_-_185578621	0.315	NM_000460 NM_001177597 NM_001177598	THPO	thrombopoietin
chr2_-_8895129	0.314	NM_020738	KIDINS220	kinase D-interacting substrate, 220kDa
chr19_+_54149941	0.314		BAX	BCL2-associated X protein
chr4_+_144325533	0.314		USP38	ubiquitin specific peptidase 38
chr22_+_18388602	0.313	NM_152906	C22orf25	chromosome 22 open reading frame 25
chr3_+_159845086	0.312		GFM1	G elongation factor, mitochondrial 1
chr1_+_210275541	0.311	NM_016448	DTL	denticleless homolog (Drosophila)
chr20_+_43953372	0.311		CTSA	cathepsin A
chr16_-_65510230	0.311	NM_004062	CDH16	cadherin 16, KSP-cadherin
chr2_-_20114881	0.310		LAPTM4A	lysosomal protein transmembrane 4 alpha
chr19_+_54149843	0.310	NM_004324 NM_138761 NM_138763 NM_138764	BAX	BCL2-associated X protein
chr6_-_53321658	0.310		ELOVL5	ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)
chr2_-_217267742	0.309		IGFBP5	insulin-like growth factor binding protein 5
chr3_+_159845067	0.308		GFM1	G elongation factor, mitochondrial 1
chr20_+_43953331	0.308		CTSA	cathepsin A
chr20_+_43952997	0.307	NM_000308 NM_001127695 NM_001167594	CTSA	cathepsin A
chr17_-_44226595	0.307	NM_173623	TTLL6	tubulin tyrosine ligase-like family, member 6
chr9_-_13269562	0.307		MPDZ	multiple PDZ domain protein
chr1_-_154205675	0.306		ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr1_-_234834410	0.305	NM_018072	HEATR1	HEAT repeat containing 1
chr1_-_57204208	0.304	NM_000066	C8B	complement component 8, beta polypeptide
chr16_+_5023672	0.304		LOC100507589	hypothetical LOC100507589

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.10	5.64e-08	GO:0009987	cellular process
1.26	2.25e-05	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.23	6.68e-05	GO:0006807	nitrogen compound metabolic process
1.23	8.49e-05	GO:0034641	cellular nitrogen compound metabolic process
1.18	3.48e-04	GO:0044260	cellular macromolecule metabolic process
1.27	4.40e-04	GO:0090304	nucleic acid metabolic process
1.16	6.10e-04	GO:0043170	macromolecule metabolic process
1.13	7.92e-04	GO:0044237	cellular metabolic process
1.47	8.34e-04	GO:0046907	intracellular transport
1.28	2.01e-03	GO:0010467	gene expression
1.11	6.29e-03	GO:0008152	metabolic process
1.28	6.49e-03	GO:0016070	RNA metabolic process
1.34	1.55e-02	GO:0051649	establishment of localization in cell
1.67	1.93e-02	GO:0032870	cellular response to hormone stimulus
1.31	2.04e-02	GO:0033036	macromolecule localization

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.11	1.27e-13	GO:0044424	intracellular part
1.11	4.06e-13	GO:0005622	intracellular
1.13	5.24e-11	GO:0043229	intracellular organelle
1.12	5.93e-11	GO:0043226	organelle
1.14	1.57e-10	GO:0043231	intracellular membrane-bounded organelle
1.14	1.76e-10	GO:0043227	membrane-bounded organelle
1.14	8.26e-10	GO:0005737	cytoplasm
1.18	2.93e-08	GO:0044422	organelle part
1.17	1.25e-07	GO:0044444	cytoplasmic part
1.18	1.35e-07	GO:0044446	intracellular organelle part
1.14	2.40e-04	GO:0005634	nucleus
1.18	1.60e-03	GO:0032991	macromolecular complex
1.23	3.77e-03	GO:0005829	cytosol
1.22	4.41e-03	GO:0044428	nuclear part
1.21	6.10e-03	GO:0031974	membrane-enclosed lumen
1.18	6.59e-03	GO:0043234	protein complex
1.21	8.61e-03	GO:0043233	organelle lumen
1.21	8.89e-03	GO:0070013	intracellular organelle lumen
1.21	1.37e-02	GO:0031090	organelle membrane
1.26	2.80e-02	GO:0005739	mitochondrion
1.22	3.21e-02	GO:0031981	nuclear lumen

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.22	5.66e-19	GO:0005515	protein binding
1.09	5.35e-09	GO:0005488	binding
1.38	2.37e-02	GO:0019899	enzyme binding
1.52	4.19e-02	GO:0000988	protein binding transcription factor activity
1.52	4.19e-02	GO:0000989	transcription factor binding transcription factor activity