• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: PDX1.p2

Z-value: 0.535

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_+_62835759	0.683	NM_014495	ANGPTL3	angiopoietin-like 3
chr6_-_133076873	0.538	NM_004666	VNN1	vanin 1
chr2_-_165768798	0.471	NM_001081676 NM_001081677 NM_006922	SCN3A	sodium channel, voltage-gated, type III, alpha subunit
chr6_-_52060327	0.417	NM_138694 NM_170724	PKHD1	polycystic kidney and hepatic disease 1 (autosomal recessive)
chr5_-_119768430	0.387
chr17_-_36890877	0.383	NM_002280	KRT35	keratin 35
chr21_+_44844924	0.367	NM_198689	KRTAP10-7	keratin associated protein 10-7
chr4_+_109033868	0.357	NM_001136257 NM_152621	SGMS2	sphingomyelin synthase 2
chr3_+_176059763	0.345	NM_207015	NAALADL2	N-acetylated alpha-linked acidic dipeptidase-like 2
chr5_+_147628567	0.344	NM_001040129	SPINK13	serine peptidase inhibitor, Kazal type 13 (putative)
chr3_-_21767819	0.343	NM_024697	ZNF385D	zinc finger protein 385D
chr4_-_69116839	0.315	NM_001077	UGT2B17	UDP glucuronosyltransferase 2 family, polypeptide B17
chr4_+_86615275	0.295	NM_001025616	ARHGAP24	Rho GTPase activating protein 24
chr6_-_31215089	0.283	NM_014069	PSORS1C2	psoriasis susceptibility 1 candidate 2
chr16_-_69114931	0.276	NM_001195139 NM_015386	COG4	component of oligomeric golgi complex 4
chr10_-_62002672	0.274		ANK3	ankyrin 3, node of Ranvier (ankyrin G)
chr18_-_45630154	0.258		MYO5B	myosin VB
chr4_+_123380569	0.254		KIAA1109	KIAA1109
chr7_-_128330615	0.254		KCP	kielin/chordin-like protein
chr15_+_46285789	0.250	NM_000338 NM_001184832	SLC12A1	solute carrier family 12 (sodium/potassium/chloride transporters), member 1
chr8_+_76614757	0.223	NM_004133	HNF4G	hepatocyte nuclear factor 4, gamma
chr6_+_72979234	0.217	NM_001168407 NM_001168408	RIMS1	regulating synaptic membrane exocytosis 1
chr6_-_26151863	0.214	NM_021062	HIST1H2BB	histone cluster 1, H2bb
chr18_+_606671	0.207	NM_199167	CLUL1	clusterin-like 1 (retinal)
chr8_-_17624304	0.187	NM_001166393	MTUS1	microtubule associated tumor suppressor 1
chr3_+_116824840	0.176	NM_001130064 NM_002045	GAP43	growth associated protein 43
chr10_+_116687904	0.169	NM_139169	TRUB1	TruB pseudouridine (psi) synthase homolog 1 (E. coli)
chr15_-_42756377	0.166	NM_001145112	PATL2	protein associated with topoisomerase II homolog 2 (yeast)
chr10_+_63478974	0.165		ARID5B	AT rich interactive domain 5B (MRF1-like)
chr14_-_76958984	0.164	NM_138791 NM_001113475	C14orf148	chromosome 14 open reading frame 148
chr1_+_36409277	0.160		MAP7D1	MAP7 domain containing 1
chr1_+_157246305	0.158	NM_005531	IFI16	interferon, gamma-inducible protein 16
chr1_+_184532027	0.157	NM_001127708 NM_001127709 NM_001127710 NM_005807	PRG4	proteoglycan 4
chr12_-_48902692	0.155	NM_001113547	LIMA1	LIM domain and actin binding 1
chr9_-_8723893	0.152	NM_001040712 NM_001171025 NM_130391 NM_130392 NM_130393	PTPRD	protein tyrosine phosphatase, receptor type, D
chr3_-_145049853	0.150	NM_173653	SLC9A9	solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr1_+_69998445	0.150	NM_020794	LRRC7	leucine rich repeat containing 7
chr16_+_69115189	0.146	NM_012426	SF3B3	splicing factor 3b, subunit 3, 130kDa
chr1_+_161305188	0.145	NM_005613	RGS4	regulator of G-protein signaling 4
chr16_+_69115227	0.142		SF3B3	splicing factor 3b, subunit 3, 130kDa
chr6_-_134540666	0.138	NM_001143677	SGK1	serum/glucocorticoid regulated kinase 1
chr16_+_69115225	0.136		SF3B3	splicing factor 3b, subunit 3, 130kDa
chr2_+_113452066	0.130	NM_019618	IL1F9	interleukin 1 family, member 9
chr12_-_119938667	0.109	NM_022895	C12orf43	chromosome 12 open reading frame 43
chr21_-_44824907	0.109	NM_198694	KRTAP10-5	keratin associated protein 10-5
chrX_+_77041612	0.108	NM_001866	COX7B	cytochrome c oxidase subunit VIIb
chrX_+_110252960	0.107	NM_001128168 NM_001128172 NM_001128173	PAK3	p21 protein (Cdc42/Rac)-activated kinase 3
chr22_-_16070778	0.106	NM_017424	CECR1	cat eye syndrome chromosome region, candidate 1
chr1_+_78858675	0.104	NM_006820	IFI44L	interferon-induced protein 44-like
chr8_-_81155564	0.103	NM_001025252	TPD52	tumor protein D52
chr12_-_119938593	0.101		C12orf43	chromosome 12 open reading frame 43
chr1_+_161305558	0.101	NM_001113381	RGS4	regulator of G-protein signaling 4
chr10_+_118177371	0.100	NM_001011709	PNLIPRP3	pancreatic lipase-related protein 3
chr1_-_33613729	0.098	NM_198040	PHC2	polyhomeotic homolog 2 (Drosophila)
chr6_-_41362370	0.098	NM_018643	TREM1	triggering receptor expressed on myeloid cells 1
chr1_+_28637247	0.096	NM_023923	PHACTR4	phosphatase and actin regulator 4
chr3_+_101720753	0.093		TMEM45A	transmembrane protein 45A
chr7_+_116182676	0.092
chr7_-_92615593	0.090	NM_152703	SAMD9L	sterile alpha motif domain containing 9-like
chr2_-_158008763	0.089	NM_004288	CYTIP	cytohesin 1 interacting protein
chr12_+_79362256	0.089	NM_001145026	PTPRQ	protein tyrosine phosphatase, receptor type, Q
chr5_+_140698537	0.088	NM_018915 NM_032009	PCDHGA2	protocadherin gamma subfamily A, 2
chr4_+_77575276	0.083	NM_020859	SHROOM3	shroom family member 3
chr14_+_20580224	0.077	NM_032572	RNASE7	ribonuclease, RNase A family, 7
chr3_+_199363633	0.077	NM_001145248	FAM157A	family with sequence similarity 157, member A
chr14_-_46882144	0.077	NM_182830	MDGA2	MAM domain containing glycosylphosphatidylinositol anchor 2
chr3_+_35658852	0.077	NM_016300	ARPP21	cAMP-regulated phosphoprotein, 21kDa
chr6_-_131333173	0.076		EPB41L2	erythrocyte membrane protein band 4.1-like 2
chr1_-_20122638	0.076	NM_014589	PLA2G2E	phospholipase A2, group IIE
chr10_+_90474280	0.076	NM_001080518	LIPK	lipase, family member K
chr12_-_102968044	0.075	NM_031302	GLT8D2	glycosyltransferase 8 domain containing 2
chr2_+_105799354	0.073		NCK2	NCK adaptor protein 2
chr18_-_49944986	0.073		MBD2	methyl-CpG binding domain protein 2
chr17_+_7900926	0.072
chr4_+_53975597	0.070		FIP1L1	FIP1 like 1 (S. cerevisiae)
chr1_+_40635058	0.070	NM_001198980	SMAP2	small ArfGAP2
chr22_-_23665312	0.067	NM_001001663	TMEM211	transmembrane protein 211
chr12_-_54150188	0.066	NM_001005499	OR6C70	olfactory receptor, family 6, subfamily C, member 70
chr6_-_138581319	0.065	NM_021635	PBOV1	prostate and breast cancer overexpressed 1
chr8_-_17599438	0.065	NM_020749	MTUS1	microtubule associated tumor suppressor 1
chr11_+_55162409	0.064	NM_001004124	OR4P4	olfactory receptor, family 4, subfamily P, member 4
chr7_+_143423073	0.063	NM_001004135	OR2A12	olfactory receptor, family 2, subfamily A, member 12
chr9_+_33614214	0.063		ANXA2P2	annexin A2 pseudogene 2
chr1_+_157676135	0.056	NM_012351	OR10J1	olfactory receptor, family 10, subfamily J, member 1
chr11_+_61732715	0.054	NM_002407	SCGB2A1	secretoglobin, family 2A, member 1
chr6_+_144654565	0.053	NM_007124	UTRN	utrophin
chr18_+_59374372	0.052	NM_080474	SERPINB12	serpin peptidase inhibitor, clade B (ovalbumin), member 12
chr7_+_93373755	0.050	NM_021955	GNGT1	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr1_-_150463292	0.050	NM_001009931	HRNR	hornerin
chr9_+_124416768	0.049	NM_012364	OR1Q1	olfactory receptor, family 1, subfamily Q, member 1
chr2_-_99412694	0.048		REV1	REV1 homolog (S. cerevisiae)
chr7_-_44195405	0.047	NM_000162	GCK	glucokinase (hexokinase 4)
chr19_-_56229808	0.046	NM_019598 NM_145894 NM_145895	KLK12	kallikrein-related peptidase 12
chr1_-_150328153	0.046	NM_001008536	TCHHL1	trichohyalin-like 1
chrX_+_118592879	0.045		UBE2A	ubiquitin-conjugating enzyme E2A (RAD6 homolog)
chr17_-_36409632	0.045	NM_031959	KRTAP3-2	keratin associated protein 3-2
chr9_+_33016482	0.044		DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1
chr21_-_30631882	0.043	NM_001077711	KRTAP27-1	keratin associated protein 27-1
chr3_+_149930656	0.043	NM_032049	AGTR1	angiotensin II receptor, type 1
chr17_-_36418869	0.042	NM_031958	KRTAP3-1	keratin associated protein 3-1
chr6_+_147566559	0.042		STXBP5	syntaxin binding protein 5 (tomosyn)
chr2_+_169634330	0.042		DHRS9	dehydrogenase/reductase (SDR family) member 9
chr10_-_56230953	0.042	NM_001142763 NM_001142764 NM_001142765 NM_001142766 NM_001142767 NM_001142768 NM_001142769 NM_001142770 NM_001142771 NM_001142772 NM_001142773 NM_033056	PCDH15	protocadherin-related 15
chrX_+_118592568	0.041		UBE2A	ubiquitin-conjugating enzyme E2A (RAD6 homolog)
chr13_-_109236897	0.041	NM_003749	IRS2	insulin receptor substrate 2
chr18_+_29573152	0.040		ASXL3	additional sex combs like 3 (Drosophila)
chr4_+_74500748	0.039		ALB	albumin
chr3_-_110155237	0.038	NM_005459	GUCA1C	guanylate cyclase activator 1C
chr1_-_161379606	0.037		RGS5	regulator of G-protein signaling 5
chr8_+_92330691	0.037	NM_052832 NM_134266	SLC26A7	solute carrier family 26, member 7
chr17_-_39499527	0.036		LSM12	LSM12 homolog (S. cerevisiae)
chr3_+_11153778	0.035	NM_001098213	HRH1	histamine receptor H1
chr1_-_202402043	0.034	NM_000537	REN	renin
chr10_+_94584449	0.034	NM_001013848	EXOC6	exocyst complex component 6
chr12_+_74071145	0.033	NM_152436	GLIPR1L2	GLI pathogenesis-related 1 like 2
chr10_+_86174665	0.033		FAM190B	family with sequence similarity 190, member B
chr5_-_142795269	0.033	NM_001018074 NM_001018075 NM_001018077	NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr2_-_46988449	0.032		MCFD2	multiple coagulation factor deficiency 2
chr3_+_185253528	0.032	NM_130770	HTR3C	5-hydroxytryptamine (serotonin) receptor 3, family member C
chr4_-_39199527	0.031		UGDH	UDP-glucose 6-dehydrogenase
chr11_+_6823458	0.030	NM_178168	OR10A5	olfactory receptor, family 10, subfamily A, member 5
chr17_-_45629401	0.029
chr9_-_21218132	0.029	NM_021268	IFNA17	interferon, alpha 17
chr17_-_7023378	0.028	NM_001197216 NM_001671	ASGR1	asialoglycoprotein receptor 1
chr2_+_24660849	0.028	NM_003743 NM_147223 NM_147233	NCOA1	nuclear receptor coactivator 1
chr4_-_24590867	0.028	NM_173463	CCDC149	coiled-coil domain containing 149
chr12_+_10074542	0.027	NM_207345	CLEC9A	C-type lectin domain family 9, member A
chr11_-_4893468	0.025	NM_001005238	OR51G2	olfactory receptor, family 51, subfamily G, member 2
chr1_+_151456683	0.025	NM_001195571	PRR9	proline rich 9
chr1_-_246869181	0.024	NM_001001827	OR2T35	olfactory receptor, family 2, subfamily T, member 35
chr14_-_80934523	0.024	NM_033104	STON2	stonin 2
chr8_+_11877238	0.023	NM_001033017	DEFB135	defensin, beta 135
chr21_-_30666417	0.022	NM_181621	KRTAP13-2	keratin associated protein 13-2
chr1_-_156657279	0.021	NM_001004476	OR10K2	olfactory receptor, family 10, subfamily K, member 2
chr18_-_28247193	0.021
chr12_+_74071116	0.021		GLIPR1L2	GLI pathogenesis-related 1 like 2
chr11_-_66201894	0.021		RBM4B	RNA binding motif protein 4B
chr12_-_10853940	0.020	NM_023917	TAS2R9	taste receptor, type 2, member 9
chr11_-_62213946	0.020	NM_203422	LRRN4CL	LRRN4 C-terminal like
chrX_+_99786044	0.019		SRPX2	sushi-repeat containing protein, X-linked 2
chr1_-_245942679	0.019	NM_001005286	OR6F1	olfactory receptor, family 6, subfamily F, member 1
chr18_+_54039730	0.019	NM_001144966	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr5_+_140181405	0.018	NM_018908 NM_031501	PCDHA5	protocadherin alpha 5
chr12_-_52306348	0.018	NM_001130060 NM_006856	ATF7	activating transcription factor 7
chr12_+_4700012	0.017	NM_017417	GALNT8	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 8 (GalNAc-T8)
chr4_-_140280031	0.017	NM_201999	ELF2	E74-like factor 2 (ets domain transcription factor)
chr9_+_81377419	0.017		TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr1_-_230717850	0.016	NM_020808	SIPA1L2	signal-induced proliferation-associated 1 like 2
chr17_+_18566060	0.016	NM_001037330	TRIM16L	tripartite motif containing 16-like
chr1_-_157772420	0.016	NM_001004469	OR10J5	olfactory receptor, family 10, subfamily J, member 5
chr2_+_204440753	0.016	NM_001037631 NM_005214	CTLA4	cytotoxic T-lymphocyte-associated protein 4
chr1_+_57093030	0.015	NM_000562	C8A	complement component 8, alpha polypeptide
chrX_+_48572226	0.015	NM_181532	ERAS	ES cell expressed Ras
chr4_-_170314382	0.015		SH3RF1	SH3 domain containing ring finger 1
chr6_-_46933901	0.015		GPR116	G protein-coupled receptor 116
chr5_-_180099663	0.015	NM_001001657	OR2Y1	olfactory receptor, family 2, subfamily Y, member 1
chr17_-_36444626	0.015	NM_030966	KRTAP1-3	keratin associated protein 1-3
chr7_+_156128431	0.015	NM_001184997	RNF32	ring finger protein 32
chr2_+_227900471	0.014	NM_020194	MFF	mitochondrial fission factor
chr21_-_45173061	0.013	NM_001127491	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr6_-_29563657	0.013	NM_052967	MAS1L	MAS1 oncogene-like
chr12_+_10351683	0.012	NM_002262 NM_007334	KLRD1	killer cell lectin-like receptor subfamily D, member 1
chr14_-_57133361	0.012	NM_001080455	SLC35F4	solute carrier family 35, member F4
chr1_-_31251315	0.011		PUM1	pumilio homolog 1 (Drosophila)
chr11_-_5130174	0.011	NM_012375	OR52A1	olfactory receptor, family 52, subfamily A, member 1
chr5_+_140207540	0.011	NM_014005 NM_031857	PCDHA9	protocadherin alpha 9
chr12_+_21417068	0.011	NM_000415	IAPP	islet amyloid polypeptide
chr2_+_17861266	0.011	NM_001105569	MSGN1	mesogenin 1
chr2_+_38746742	0.010		GALM	galactose mutarotase (aldose 1-epimerase)
chr3_-_152517204	0.010	NM_023915	GPR87	G protein-coupled receptor 87
chr3_+_35697432	0.010	NM_198399	ARPP21	cAMP-regulated phosphoprotein, 21kDa
chr1_-_153915867	0.010
chr18_+_54039818	0.010		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr11_+_89458765	0.009	NM_001143975	UBTFL1	upstream binding transcription factor, RNA polymerase I-like 1
chr6_-_39180390	0.009		C6orf64	chromosome 6 open reading frame 64
chrX_+_123307812	0.009	NM_001114937 NM_002351	SH2D1A	SH2 domain containing 1A
chr7_-_11643113	0.009		THSD7A	thrombospondin, type I, domain containing 7A
chr17_-_36113502	0.008	NM_019016	KRT24	keratin 24
chr17_-_39499463	0.007		LSM12	LSM12 homolog (S. cerevisiae)
chr6_+_158653679	0.007	NM_001007466 NM_020245	TULP4	tubby like protein 4
chr10_+_70650064	0.006	NM_025130	HKDC1	hexokinase domain containing 1
chrX_+_48978870	0.006	NM_014008	CCDC22	coiled-coil domain containing 22
chr17_+_73511843	0.005	NM_001142640 NM_018996	TNRC6C	trinucleotide repeat containing 6C
chr2_-_218516950	0.005	NM_022648	TNS1	tensin 1
chr17_-_1195096	0.005		PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr7_+_120752656	0.004	NM_016087	WNT16	wingless-type MMTV integration site family, member 16
chr1_+_84382575	0.003		PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr20_+_43423990	0.003	NM_001197129	SYS1	SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chrX_-_131375217	0.002	NM_001170701 NM_001170702 NM_001170703	MBNL3	muscleblind-like 3 (Drosophila)
chr3_-_139315011	0.002	NM_001170538	DZIP1L	DAZ interacting protein 1-like
chr17_+_35372751	0.002	NM_178171	GSDMA	gasdermin A
chr11_-_5279750	0.002	NM_033179	OR51B4	olfactory receptor, family 51, subfamily B, member 4
chr3_-_115826481	0.001	NM_001164346	ZBTB20	zinc finger and BTB domain containing 20
chr9_+_96561750	0.001	NM_001193329	C9orf3	chromosome 9 open reading frame 3
chr4_+_95595419	0.001		PDLIM5	PDZ and LIM domain 5
chr11_-_57883117	0.000	NM_001005489	OR5B17	olfactory receptor, family 5, subfamily B, member 17

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
3.67	4.74e-03	GO:0007606	sensory perception of chemical stimulus
3.85	5.29e-03	GO:0007608	sensory perception of smell
2.64	4.17e-02	GO:0007600	sensory perception

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.62	3.04e-03	GO:0071944	cell periphery
5.40	5.93e-03	GO:0005882	intermediate filament
1.56	1.52e-02	GO:0005886	plasma membrane
4.68	1.80e-02	GO:0045111	intermediate filament cytoskeleton

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
4.03	7.53e-04	GO:0004984	olfactory receptor activity
2.68	5.68e-03	GO:0004930	G-protein coupled receptor activity
1.87	2.40e-02	GO:0004871	signal transducer activity
1.87	2.40e-02	GO:0060089	molecular transducer activity
1.96	3.04e-02	GO:0004872	receptor activity